Mesa County, CO Mixed-use properties for Rent & Lease

Updated: Jul 24, 2025

Mixed-Use Property with Vanilla Shell

2388 Patterson Road, Grand Junction, CO 81505

$4,400/Mo

10,775 sqft

10,775 square feet of planned commercial space
New construction with completion targeted by the end of 2026 2nd quarter
Retail or professional office use
Stone and stucco exterior
Vanilla shell interior

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Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 1 Active listings in Mesa County, CO, we suggest exploring alternatives. Similar 20 Properties for Sales.

Similar Spaces for Sale in Mesa County, CO

Consider Similar Space for Sale. We found 20 Spaces matching your search parameters.

Mixed-Use Property with Shop Space

2180 I-70 Frontage Rd, De Beque, CO 81630

$2,800,000

14,000 sqft

Office, two-bay shop, and rear industrial workspace include overhead crane equipment.

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Mixed-Use Office/Retail Building

2497 Highway 6 And 50, Grand Junction, CO 81505

$789,000

0.36 AC lot

Office and retail building with highway frontage near Mesa Mall.

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Mixed-Use Property with Storage

2960 North Ave, Grand Junction, CO 81504

Contact for pricing

4,369 sqft 0.60 AC lot

C-2-zoned property combines office, retail, residential, and dry storage improvements along North Avenue.

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Mixed-Use Property with Medical Improvements

1129 Colorado Avenue, Grand Junction, CO 81501

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25,103 sqft 1.85 AC lot

Multi-parcel commercial asset with existing buildings, paved parking, outdoor areas, and zoning supporting varied mixed-use applications.

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Orchard Mesa Commercial Property

2706 HWY 50, Grand Junction, CO 81503

Contact for pricing

1,440 sqft 0.60 AC lot

Turnkey commercial property with drive-thru, high visibility, and expansion potential.

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Retail and Office Mixed-Use Building

575 25 Road, Grand Junction, CO 81505

$795,000

Positioned near Patterson Road, the property provides convenient access to a major commercial corridor.

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Remodeled Mixed-Use Property

535 N 7th Street, Grand Junction, CO 81501

$998,500

Two updated floors and balcony space support office, medical, residential, and other configurations.

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Mixed-Use Property with Apartment

418 S 7th Street, Grand Junction, CO 81501

$499,000

Downtown commercial property combines a former retail layout, upper-level apartment, warehouse storage, and on-site parking.

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Mixed-Use Property with Stone Fireplace

1043 N River Road, Palisade, CO 81526

$485,000

Interior amenities include a private office, storage room, restrooms, and employee break area.

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Mixed-Use Property With Storage

2960 North Avenue, Grand Junction, CO 81504

$595,000

Office, retail, residential, and dry-storage components occupy a C-2-zoned commercial site.

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Mixed-Use Property with Separate Entrances

1317 N 3rd Street, Grand Junction, CO 81501

$440,000

Two-sided layout with on-site parking, a private yard, and flexible commercial or office use potential.

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Commercial Land with Bungalow

551 E Grand Avenue, Fruita, CO 81521

$425,000

An existing 1925 bungalow occupies a downtown mixed-use parcel suited to neighborhood-friendly commercial activity.

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Industrial Flex Space with Shops

2802 C 3/4 Road, Grand Junction, CO 81501

Contact for pricing

1.14 AC lot

Three contiguous parcels combine shop infrastructure, private offices, and integrated utilities for flexible commercial use.

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Historic School Building

930 Ute Avenue, Grand Junction, CO 81501

$1,700,000

Existing school improvements occupy a substantial downtown parcel with flexibility for future redevelopment concepts.

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Mixed-Use Property with Fuel Station

320 Minter Avenue, De Beque, CO 81630

$450,000

Retail, deli, fuel, and convenience components create a varied commercial operation with both real estate and business offered.

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Mixed-Use Property with Courtyard

2997 North Avenue, Grand Junction, CO 81504

$300,000

Former coffee-house layout includes an exterior pass-through window and front-room receiving area.

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Mixed-Use Hotel Property

2210 Highway 6&50, Grand Junction, CO 81501

$7,400,000

The property brings together guest lodging, a restaurant, leased office suites, and a separately occupied warehouse.

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Shop with Office and Yard

1162 Ute Ave, Grand Junction, CO 81501

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1,296 sqft 0.43 AC lot

Downtown Grand Junction shop with office, yard, and development potential.

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Fruita Commercial Zoned Bungalow

551 E Grand Ave, Fruita, CO 81521

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900 sqft 0.55 AC lot

1925 bungalow in commercial zone with development potential.

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Rectangular Mixed-Use Land

2385 G Road, Grand Junction, CO 81505

$4,250,000

7.81 AC lot

Open commercial land with mixed-use zoning and frontage along G Road in Grand Junction.

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Mesa County, CO Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in Mesa County, CO with 1 listings featured on our commercial real estate exchange. The current inventory includes 10,775 square feet of properties with an estimated lease value of $4.90.

Estimated lease rates for Mixed-use properties in Mesa County, CO average $4.90 SF/Yr.

Featured Mesa County Real Estate Agencies

Realmo connects you with licensed Mesa County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Heiden Homes Realty & Associates

735 Rood Avenue Grand Junction, CO 81501

Phone: 19702457777

Mesa County, CO Mixed-use Properties for Lease

2388 Patterson Road, Grand Junction, CO 81505