Mesa County, CO Mixed-use properties for Rent & Lease

Updated: Jul 24, 2025

Mixed-Use Property with Vanilla Shell

2388 Patterson Road, Grand Junction, CO 81505

$4,400/Mo

10,775 sqft

10,775 square feet of planned commercial space
New construction with completion targeted by the end of 2026 2nd quarter
Retail or professional office use
Stone and stucco exterior
Vanilla shell interior

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Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 1 Active listings in Mesa County, CO, we suggest exploring alternatives. Similar 19 Properties for Sales.

Similar Spaces for Sale in Mesa County, CO

Consider Similar Space for Sale. We found 19 Spaces matching your search parameters.

Orchard Mesa Commercial Property

2706 Highway 50, Grand Junction, CO 81503

$565,000

1,440 sqft 0.60 AC lot

Turnkey commercial property with drive-thru, high visibility, and expansion potential.

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Mixed-Use Office/Retail Building

2497 Highway 6 And 50, Grand Junction, CO 81505

$789,000

0.36 AC lot

Office and retail building with highway frontage near Mesa Mall.

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Commercial Land for Mixed-Use Development

2691 Highway 50, Grand Junction, CO 81503

$429,000

0.58 AC lot

Commercial land on Hwy 50 with utilities in place and multifamily use permitted for an 8-unit apartment complex.

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Commercial Development Land

2691 Highway 50, Grand Junction, CO 81503

$429,000

0.58 AC lot

Highway 50 parcel with public utilities and multifamily development permitted.

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Remodeled Mixed-Use Property

535 N 7th Street, Grand Junction, CO 81501

$1,250,000

Two updated floors and balcony space support office, medical, residential, and other configurations.

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Commercial Flex Building with Residence

321 Pitkin Ave, Grand Junction, CO 81501

Contact for pricing

4,200 sqft

Versatile commercial flex building with residential home in downtown.

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Mixed-Use Property With Storage

2960 North Avenue, Grand Junction, CO 81504

$595,000

Office, retail, residential, and dry-storage components occupy a C-2-zoned commercial site.

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Mixed-Use Property with Stone Fireplace

1043 N River Road, Palisade, CO 81526

$485,000

Interior amenities include a private office, storage room, restrooms, and employee break area.

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Mixed-Use Building with Basement Entrance

303 North Avenue, Grand Junction, CO 81501

$330,000

Standalone commercial property with prominent signage, flexible space, and parking on the lot.

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MU-1 Corner Commercial Land

2810 Bunting Avenue, Grand Junction, CO 81501

$338,000

1.12 AC lot

Corner commercial land with nearby utilities, completed off-site improvements, and mixed-use development potential.

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Historic School Building

930 W Ute Avenue, Grand Junction, CO 81501

$1,900,000

Downtown property combines a substantial school building with an approximately 1.15-acre site.

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Mixed-Use Retail/Office Building

575 25 Road, Grand Junction, CO 81505

$795,000

Commercial space positioned along a busy corridor with convenient Patterson Road access.

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Mixed-Use Property with Fuel Station

320 Minter Avenue, De Beque, CO 81630

$480,000

Retail, deli, fuel, and convenience components create a varied commercial operation with both real estate and business offered.

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Live-Work Space with Two Rooms

346 Main Street, Grand Junction, CO 81501

$1,659,000

Flexible interior includes divided rooms, a half-bath, and glass-panel separation from the residence.

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Commercial Land with Existing Improvements

2379 G Road, Grand Junction, CO 81505

$2,500,000

Mixed Use-zoned acreage includes a fenced shop and office building alongside established medical facilities.

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Mixed-Use Property with Courtyard

2997 North Avenue, Grand Junction, CO 81504

$300,000

Former coffee-house layout includes an exterior pass-through window and front-room receiving area.

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Shop with Office and Yard

1162 Ute Ave, Grand Junction, CO 81501

Contact for pricing

1,296 sqft 0.43 AC lot

Downtown Grand Junction shop with office, yard, and development potential.

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Fruita Commercial Zoned Bungalow

551 E Grand Ave, Fruita, CO 81521

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900 sqft 0.55 AC lot

1925 bungalow in commercial zone with development potential.

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Commercial Land with Existing Bungalow

551 E Grand Avenue, Fruita, CO 81521

$425,000

C-1 zoning includes an existing bungalow and future Downtown Mixed Use designation.

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Mesa County, CO Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in Mesa County, CO with 1 listings featured on our commercial real estate exchange. The current inventory includes 10,775 square feet of properties with an estimated lease value of $4.90.

Estimated lease rates for Mixed-use properties in Mesa County, CO average $4.90 SF/Yr.

Featured Mesa County Real Estate Agencies

Realmo connects you with licensed Mesa County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Heiden Homes Realty & Associates

735 Rood Avenue Grand Junction, CO 81501

Phone: 19702457777

Mesa County, CO Mixed-use Properties for Lease

2388 Patterson Road, Grand Junction, CO 81505