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    South Carolina Medical Space for Lease

    10 results
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    Premier Commercial Space on Lady's Island
    $3,800 / Mo
    1,307 SF

    Premier Commercial Space on Lady's Island

    8 Celadon Dr, Beaufort, SC 29907

    Two-story commercial space with high visibility on Sam's Point Road.

    • Maximum visibility and dedicated signage on Sam's Point Road.
    • Versatile, open‑concept layout with approximately 2,250 sq ft of modern, high‑end commercial space.
    • Modified Gross Lease at $4,000/month includes HOA, property taxes, building insurance, water, and trash collection.
    • Ground floor features an open floor plan with polished concrete floors.
    • Upper floor includes a mix of wood flooring, multiple rooms/offices, a private entrance, and a kitchenette.
    Updated: Feb 20
    View details
    Retail Center Renovation in Little River
    $1,913 / Mo
    1,148 SF

    Retail Center Renovation in Little River

    4390 Spa Dr, Little River, SC 29566

    Retail and office spaces available in renovated Little River center.

    • Comprehensive renovation planned for completion in 2027, modernizing the property into a coastal‑inspired retail destination.
    • Flexible demising options allow for tenant spaces ranging from 1,100 SF to over 4,000 SF, accommodating diverse business needs.
    • Designed for a variety of uses including retail, medical, wellness, office, and food‑and‑beverage, broadening potential tenant base.
    • Modern coastal architectural design with enhanced storefront visibility, covered walkways, and a central focal point to attract customers.
    • Approximately 27,000 SF of space across multiple connected structures, including a main building with a second‑floor opportunity.
    Updated: Jan 22
    View details
    Renovated Shopping Center in Forest Acres
    Contact for pricing
    15,630 SF

    Renovated Shopping Center in Forest Acres

    Premier shopping center with upscale tenants in a desirable location.

    2710 Gervais St, Columbia, SC 29204
    View details
    Retail and Office Space Available
    $30 SF/Yr
    1,816 SF

    Retail and Office Space Available

    Retail and medical office spaces for lease in Rock Hill.

    2460 India Hook Rd, Rock Hill, SC 29732
    View details
    New Retail/Office/Medical Space Available
    $35 SF/Yr
    8,450 SF

    New Retail/Office/Medical Space Available

    New retail, office, or medical spaces available in NE Columbia.

    565 Spears Creek Church Rd, Elgin, SC 29045
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    Retail Space in Surfside Beach
    Contact for pricing

    Retail Space in Surfside Beach

    Multi-tenant building for lease in the heart of Surfside Beach.

    Surfside Beach, SC 29575
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    Greer Retail/Office/Medical Space For Rent
    $14 SF/Yr
    2,100 SF

    Greer Retail/Office/Medical Space For Rent

    Flexible 2,100 SF space ideal for retail, office, or medical.

    1317 West Poinsett Street Ext, Greer, SC 29651
    View details
    Pleasantburg Drive Office Building
    Contact for pricing
    1,800 SF

    Pleasantburg Drive Office Building

    1,800 SF office building for lease on 0.48 acres.

    1934 N Pleasantburg Dr, Greenville, SC 29609
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    Medical Office Space For Rent
    Contact for pricing
    3,649 SF

    Medical Office Space For Rent

    New construction medical office space with connection to hospital.

    986 Wellness Way, Fort Mill, SC
    View details
    ParkStone at Indian Land: Prime Retail Space
    Contact for pricing
    12,500 SF

    ParkStone at Indian Land: Prime Retail Space

    High-profile retail & land, Indian Land.

    8004 Shelley Mullis Rd, Fort Mill, SC 29707
    View details
    Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 10 Active listings in South Carolina, we suggest exploring alternatives. Similar 15 Properties for Sales.

    Explore Similar Spaces for Sale in South Carolina

    Consider Similar Space for Sale. We found 15 Spaces in Nearby Locations matching your search parameters.

    Belvedere Office/Activities Center For Sale
    $995,000
    6,889 SF

    Belvedere Office/Activities Center For Sale

    Single-story office building on 2.5 acres, suitable for various uses.

    725 Edgefield Rd, Belvedere, SC 29841
    View details
    Land For Retail/Office/Medical Use
    $135,000
    0.57 Acres

    Land For Retail/Office/Medical Use

    Land suitable for retail, office, or medical development.

    797 E Buena Vista Ave, North Augusta, SC 29841
    View details
    Garners Ferry Road Commercial Building
    $2,250,000
    15,593 SF

    Garners Ferry Road Commercial Building

    High-visibility commercial building with 41 suites, ideal for investment.

    7358 Garners Ferry Rd, Columbia, SC 29209
    View details
    Georgetown Industrial/Medical Remodel Opportunity
    Pending
    $699,000
    16,040 SF

    Georgetown Industrial/Medical Remodel Opportunity

    16,040 SF building on 1.82 acres, prime remodel location.

    2401 North Fraser St, Georgetown, SC 29440
    View details
    Medical Office Building For Sale
    $785,000
    4,900 SF

    Medical Office Building For Sale

    4,900 SF medical office building with significant plumbing infrastructure.

    110 Atrium Way, Columbia, SC 29223
    View details
    Medical Office Suites Near Hospital
    Contact for pricing

    Medical Office Suites Near Hospital

    Medical office suites for lease adjacent to Hilton Head Hospital.

    25 Hospital Center Blvd, Hilton Head Island, SC 29926
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    East Cooper Medical Office Building
    Contact for pricing
    60,809 SF

    East Cooper Medical Office Building

    Medical office building near East Cooper Medical Center for sale.

    1300 Hospital Dr, Mount Pleasant, SC 29464
    View details
    Stand Alone Medical Office Building
    Contact for pricing
    3,600 SF

    Stand Alone Medical Office Building

    Stand-alone medical building on Hilton Head Island, ready for occupancy.

    4101 Main St, Hilton Head Island, SC 29926
    View details
    Highway 170 Retail/Office/Medical Space
    Contact for pricing
    3,970 SF

    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for sale on Highway 170.

    48 Ter Dr, Okatie, SC 29909
    View details
    Medical Office Condo Near Prisma
    $1,980,000
    22,263 SF

    Medical Office Condo Near Prisma

    Class A medical office condo for sale or lease.

    2113 Adams Grv Rd, Columbia, SC 29203
    View details
    Turn-Key Medical Office in Columbia
    Contact for pricing
    9,875 SF

    Turn-Key Medical Office in Columbia

    Class A medical office in NE Columbia with flexible layout.

    229 Longtown Rd, Columbia, SC 29229
    View details
    Adaptable Two-Story Building For Sale
    Contact for pricing
    18,832 SF

    Adaptable Two-Story Building For Sale

    Two-story metal building suitable for office or medical redevelopment.

    7474 Garners Ferry Rd, Columbia, SC 29209
    View details
    Modern Office Campus For Sale
    $16,438,168
    54 SF

    Modern Office Campus For Sale

    Two-building office campus near downtown Charleston and Ashley Landing redevelopment.

    1176 Sam Rittenberg Blvd, Charleston, SC 29407
    View details
    Class A Medical Office Condo
    Contact for pricing
    11,131 SF

    Class A Medical Office Condo

    Class A medical office condo for sale or lease.

    2113 Adams Grv, Columbia, SC 29203
    View details

    South Carolina Medical space Leasing Opportunities Market Analysis

    Explore Medical space leasing options in South Carolina with 25 listings featured on our commercial real estate exchange. The current inventory includes 645,594,050 square feet of properties with an estimated lease value of $133 SF/Yr.

    Estimated lease rates for Medical space in South Carolina begin at $14 SF/Yr, with an average of $26 SF/Yr and extend to $35 SF/Yr.
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