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    Sikeston, MO Medical Office Space for Sale

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    Miner, MO Bertrand, MO East Prairie, MO
    Sikeston Commercial Building Investment Opportunity
    $979,500
    11,000 SF
    Sikeston Commercial Building Investment Opportunity

    808 E Wakefield Ave, Sikeston, MO 63801

    High-visibility commercial building with income and upside potential.
    • High‑visibility location near Missouri Delta Medical Center with strong daily traffic.
    • Existing cash flow from 2 of 6 currently leased units.
    • Value‑add opportunity with vacant units needing cosmetic updates.
    • Versatile space suitable for medical, office, retail, or professional services.
    • Ample customer parking and easy access.
    Updated: Mar 5
    View details
    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 1 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 9 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Two-Level Office Building For Sale
    $815,000
    9,857 SF
    Two-Level Office Building For Sale

    9,857 SF office building with multiple offices and restrooms.

    10 Doctors Park, Cape Girardeau, MO 63703

    View details
    Cape Girardeau Medical Office Building
    $270,000
    2,546 SF
    Cape Girardeau Medical Office Building

    2,546 SF medical office building in a thriving complex.

    62 Doctors Park, Cape Girardeau, MO 63703

    View details
    NNN Leased Investment Opportunity
    $2,395,000
    11,500 SF
    NNN Leased Investment Opportunity

    Single tenant building leased to the United States Government.

    2620 Perkins Creek Dr - VA CLINIC NNN LEASE, Paducah, KY 42001

    View details
    Single Tenant Investment Property
    $2,150,000
    1.24 Acres
    Single Tenant Investment Property

    Leased to U.S. Department of Veterans Affairs Outpatient Clinic.

    2620 Perkins Creek Dr, Paducah, KY

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land on Highway 61
    $144,000
    1.01 Acres
    Commercial Land on Highway 61

    Commercial land on high-traffic route near Sikeston Industrial Park.

    103 Grove Estates, Sikeston, MO 63801

    View details
    Versatile Commercial Building Near I-55
    $569,900
    3,096 SF
    Versatile Commercial Building Near I-55

    High-traffic location, built in 2017, suitable for diverse businesses.

    5598 Us Highway 61 North, Jackson, MO 63755

    View details
    Paducah Commercial Lot For Sale
    $265,000
    1.17 Acres
    Paducah Commercial Lot For Sale

    1.17 acre commercial lot in high-traffic area.

    2549 New Holt Road, Paducah, KY 42001

    View details
    Benton, KY Commercial Land
    $395,000
    5.17 Acres
    Benton, KY Commercial Land

    High visibility land near I-69, ideal for various businesses.

    501 Old Symsonia Rd, Benton, KY 42025

    View details

    Off-Market Properties in Sikeston, MO

    Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    613 Greer Ave
    MEDICAL BUILDING
    3,468 SF Lot: 0.30 Acres
    Value Estimation by Request

    613 Greer Ave, Sikeston, MO 63801

    View details
    801 Main St
    MEDICAL BUILDING
    2,254 SF Lot: 0.50 Acres
    Value Estimation by Request

    801 Main St, Sikeston, MO 63801-2171

    View details
    607 Main St
    Office Units
    Value Estimation by Request

    607 Main St, Sikeston, MO 63801

    View details
    808 Wakefield Ave
    MEDICAL BUILDING
    9,398 SF Lot: 1.35 Acres

    808 Wakefield Ave, Sikeston, MO 63801-5147

    View details
    1002 Main St
    MEDICAL BUILDING
    1,464 SF Lot: 0.45 Acres
    Value Estimation by Request

    1002 Main St, Sikeston, MO 63801-5044

    View details
    1106 Main St
    MEDICAL BUILDING
    3,369 SF Lot: 1.00 Acre
    Value Estimation by Request

    1106 Main St, Sikeston, MO 63801-5046

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    1012 Main St
    MEDICAL BUILDING
    15,140 SF Lot: 2.20 Acres
    Value Estimation by Request

    1012 Main St, Sikeston, MO 63801-5044

    View details
    710 Lk St
    MEDICAL BUILDING
    990 SF Lot: 0.30 Acres
    Value Estimation by Request

    710 Lk St, Sikeston, MO 63801-2165

    View details
    706 Kingshighway St
    MEDICAL BUILDING
    1,530 SF Lot: 0.26 Acres
    Value Estimation by Request

    706 Kingshighway St, Sikeston, MO 63801-5918

    View details

    Sikeston, MO Medical Office Space Investment Opportunities Market Analysis

    Explore 10 medical office space for sale in Sikeston, MO on our real estate platform. These investment opportunities span a total of 11,000 square feet of properties for sale, with an estimated market value of $979,500.

    Sale prices for medical spaces in Sikeston, MO start at $979,500, averaging $979,500, and reaching up to $979,500 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 12
    Office buildings 4
    Medical Office Space 3

    Demographics Overview

    Population 22K
    Population Growth (5Y) -3.7%
    Median Household Income $55,945
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Sikeston submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    63801 $979.5K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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