Add Listing
    Sikeston, MO
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price
    $
    $

    Sikeston, MO Commercial Real Estate for Sale

    Notify Me
    List
    Map
    Miner, MO Bertrand, MO East Prairie, MO
    32 results
    Sikeston Commercial Property For Sale
    $699,900
    2,196 SF
    Sikeston Commercial Property For Sale

    1207 W Malone Avenue, Sikeston, MO 63801

    Commercial property in Sikeston, Missouri, suitable for retail or automotive.
    • Durable construction featuring aluminum siding, brick, and concrete.
    • Cooling system equipped with ceiling fan(s) and electric cooling.
    • Secure exterior with security lights.
    • Features tile and ceramic tile flooring.
    • Comes with a freezer.
    Updated: May 4
    View details
    Sikeston Car Wash with Expansion Potential
    $1,000,000
    40,511 SF
    Sikeston Car Wash with Expansion Potential

    531 N Main Street, Sikeston, MO 63780

    Turnkey car wash with expansion potential in high-demand market.
    • Significant expansion/redevelopment potential due to additional land.
    • Turnkey operation with all new equipment, ensuring lower overhead.
    • Established monthly membership program provides recurring revenue and operational stability.
    • Excellent visibility and strong traffic exposure.
    • Complements existing carwash (MLS 26000082) capturing a broader customer base and reinforcing brand presence.
    Updated: Jan 8
    View details
    Sikeston Carwash with High Visibility
    $1,250,000
    40,946 SF
    Sikeston Carwash with High Visibility

    Turnkey carwash with high traffic, visibility, and recurring revenue.

    900 S Main Street, Sikeston, MO 63801

    View details
    Historic Downtown Sikeston Retail Opportunity
    $275,000
    14,642 SF
    Historic Downtown Sikeston Retail Opportunity

    Two-story retail space in high-traffic downtown Sikeston.

    124 E Front Street, Sikeston, MO 63801

    View details
    Downtown Sikeston Commercial Office Building
    $279,000
    4,273 SF
    Downtown Sikeston Commercial Office Building

    Commercial property with endless business opportunities in downtown Sikeston.

    202 S Kingshighway Street, Sikeston, MO 63801

    View details
    Multi-Tenant Storage and Commercial Space
    $549,000
    1.30 Acres
    Multi-Tenant Storage and Commercial Space

    For sale investment property with leased commercial spaces and 35 storage units on a 1.3-acre lot.

    2008 & 2010 N Main Street, Sikeston, MO 63801

    View details
    Remodeled Commercial Building in Sikeston
    $775,000
    1.67 Acres
    Remodeled Commercial Building in Sikeston

    Remodeled commercial building suitable for single or multiple tenants.

    210 S Kingshighway Street, Sikeston, MO 63801

    View details
    Sikeston Warehouse with Highway Access
    $1,100,000
    24,700 SF
    Sikeston Warehouse with Highway Access

    Large warehouse with easy access to I-55 and I-57.

    300 Matthews Lane, Sikeston, MO 63801

    View details
    Sikeston Commercial Property For Sale
    $650,000
    1.28 Acres
    Sikeston Commercial Property For Sale

    Prime commercial location with high visibility and established business history.

    1105 S Main Street, Sikeston, MO 63801

    View details
    Sikeston Retail Property For Sale
    $550,000
    1,150 SF
    Sikeston Retail Property For Sale

    Established family-owned business with high visibility for over 30 years.

    1018 Linn Street, Sikeston, MO 63801

    View details
    Historical Building in Downtown Sikeston
    $269,000
    6,321 SF
    Historical Building in Downtown Sikeston

    Two-story historic building in downtown Sikeston, ideal for investors.

    112 Front Street, Sikeston, MO 63801

    View details
    Prime Land Off I-55
    $1,200,000
    22.84 Acres
    Prime Land Off I-55

    22+ acre vacant land with high visibility and traffic.

    2338 S Acres Drive, Sikeston, MO 63801

    View details
    Sikeston Industrial Warehouse on 8+ Acres
    $350,000
    10,000 SF
    Sikeston Industrial Warehouse on 8+ Acres

    Industrial warehouse with I-55 frontage, ideal for logistics or distribution.

    608b State Highway H, Sikeston, MO 63801

    View details
    Sikeston Commercial Building Investment Opportunity
    $979,500
    11,000 SF
    Sikeston Commercial Building Investment Opportunity

    High-visibility commercial building with income and upside potential.

    808 E Wakefield Ave, Sikeston, MO 63801

    View details
    Historic Downtown Mixed-Use Opportunity
    $299,000
    14,642 SF
    Historic Downtown Mixed-Use Opportunity

    Two-story historic building in downtown Sikeston with modern potential.

    124 E Front Street, Sikeston, MO 63801

    View details
    Neighborhood Center with Established Businesses
    Contact for pricing
    7,364 SF
    Neighborhood Center with Established Businesses

    Neighborhood center with high traffic, visibility, and established businesses.

    1100 - 1105 S. Main, Sikeston, MO 63801

    View details
    Commercial Land on Highway 61
    $144,000
    1.01 Acres
    Commercial Land on Highway 61

    Commercial land on high-traffic route near Sikeston Industrial Park.

    103 Grove Estates, Sikeston, MO 63801

    View details
    Prime Land I-55 Exit 69
    $1,200,000
    994,910 SF
    Prime Land I-55 Exit 69

    High-traffic vacant land suitable for retail or restaurant development.

    2338 South Acres Drive, Sikeston, MO 63801

    View details
    Commercial Land in Sikeston, MO
    $400,000
    2.63 Acres
    Commercial Land in Sikeston, MO

    2.63 acres in booming retail and hospitality area.

    109 Stallcup Drive, Sikeston, MO 63801

    View details
    Sikeston Commercial Property with Income
    $290,000
    4,244 SF
    Sikeston Commercial Property with Income

    Commercial building, duplex, and storage on 1.22 acres.

    101-103 Donald Fulton Dr, Sikeston, MO 63801

    View details
    Commercial Land in Retail Area
    $500,000
    1.05 Acres
    Commercial Land in Retail Area

    1.05 acres of commercial land for development in Sikeston.

    1209 Lawrence, Sikeston, MO 63801

    View details
    Commercial Land in Sikeston, MO
    $500,000
    1.24 Acres
    Commercial Land in Sikeston, MO

    1.24 acre commercial lot near apartments and retail.

    1201 Lawrence, Sikeston, MO 63801

    View details
    Commercial Land Ready For Development
    $199,000
    2.00 Acres
    Commercial Land Ready For Development

    Two-acre commercial lot available for development in Sikeston, Missouri.

    224 S Interstate Drive, Sikeston, MO 63801

    View details
    Commercial Building in High Traffic
    $400,000
    7,100 SF
    Commercial Building in High Traffic

    7100 sq ft commercial building in high traffic area.

    1218 Linn St, Sikeston, MO 63801

    View details

    Sikeston, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Sikeston, MO, showcased through 32 active listings on our real estate platform. These investment opportunities span a total of 1,217,581 square feet of properties for sale, with an estimated market value of $10,191,400.

    Sale prices for business properties in Sikeston, MO start at $269,000, averaging $679,426, and reaching up to $1,250,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Property Size Breakdown

    The majority of commercial real estate listings in Sikeston fall within the 25,000 to 50,000 square foot range.

    Demographics Overview

    Population 22K
    Population Growth (5Y) -3.7%
    Median Household Income $55,945
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Sikeston submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    Sikeston $813.4K
    Scott City $1M

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Need Help?

    Reach out if you need assistance with Realmo tools or have questions about your listings

    Browse Commercial real estate for Sale Near Sikeston, MO

    Popular Searches in Sikeston, MO

    Popular Categories

    Most Searched ZIP Codes in Sikeston, MO

    • 63801
    • 63780

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!