Sikeston, MO
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    Sikeston, MO Office Spaces for Lease

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    Charleston, MO Scott City, MO Advance, MO
    12 listings
    Downtown Sikeston Office Space Available
    $4,500/Mo
    4,273 SF
    Downtown Sikeston Office Space Available

    202 S Kingshighway Street, Sikeston, MO 63801

    Commercial property in downtown Sikeston ready to be leased.
    • Prime downtown Sikeston location on a corner lot.
    • Large 7,638 sq ft building suitable for various business purposes.
    • Handicap accessible with ramp, parking, and restrooms.
    • Includes 15 parking spaces (2 handicap accessible).
    • Flexible layout with reception area, open space, offices, conference room, and break room.
    Updated: Feb 5
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    Remodeled Office Space For Lease
    $658/Mo
    1,000 SF
    Remodeled Office Space For Lease

    210 S Kingshighway Suite 200, Sikeston, MO 63801

    Recently remodeled office space with private office and bath.
    • Recently remodeled: Enjoy new flooring, paint, electrical, and lighting throughout the entire building.
    • Versatile open space: Approximately 1000 square feet of open area.
    • Private office: Includes a dedicated private office space.
    • Separate bath: Features a private and separate bathroom.
    • Common area adjacency: Adjoins a common area suitable for a waiting room or receptionist.
    Updated: May 11
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    Remodeled Office Space Available
    $790/Mo
    1,200 SF
    Remodeled Office Space Available

    Recently remodeled office space with private office and storage.

    210 S Kingshighway Suite 300, Sikeston, MO 63801

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    Remodeled Office Space Available
    $546/Mo
    800 SF
    Remodeled Office Space Available

    Recently remodeled office space with flexible layout in Sikeston, MO.

    210 S Kingshighway Suite 100, Sikeston, MO 63801

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    Sikeston Office Suite For Rent
    $3,625/Mo
    2,000 SF
    Sikeston Office Suite For Rent

    Recently-built office suite with four offices, bathroom, and kitchenette.

    912 S Main Street, Sikeston, MO 63801

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    Private Office in Remodeled Building
    $305/Mo
    Private Office in Remodeled Building

    Single office space ideal for professionals or entrepreneurs.

    210 S Kingshighway Suite 600, Sikeston, MO 63801

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    New Office/Retail Center on Main
    $1,950/Mo
    2,600 SF
    New Office/Retail Center on Main

    Prime location with excellent traffic and visibility.

    600 N. Main Street, Sikeston, MO 63801

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    New Retail/Office Space Available
    $1,950/Mo
    1,300 SF
    New Retail/Office Space Available

    Prime location with high traffic and ample parking.

    E-600 N Main Street, Sikeston, MO 63801

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    Professional Space Near Main Intersection
    $2,000/Mo
    Professional Space Near Main Intersection

    Prime location, high visibility, and flexible floor plan.

    1226 Linn St, Suite C, Sikeston, MO 63801

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    Professional Space Near Main Intersection
    $1,000/Mo
    Professional Space Near Main Intersection

    Prime location, high visibility, and flexible floor plan.

    1226 Linn St, Suite D, Sikeston, MO 63801

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    Sikeston Medical/Office Space Available
    Contact for pricing
    Sikeston Medical/Office Space Available

    Multi-tenant commercial building near Missouri Delta Medical Center.

    808 E Wakefield Ave, Sikeston, MO 63801

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    Medical Office Space Sublease
    $16 SF/Yr
    2,631 SF
    Medical Office Space Sublease

    2,631 SF medical office space available for sublease.

    1124 N Main Street, Sikeston, MO 63801

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    Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 12 Active listings in Sikeston, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Suite in Cape Girardeau
    $5,641/Mo
    6,770 SF
    Office Suite in Cape Girardeau

    Office suite with high visibility and traffic in Cape Girardeau.

    450 Siemers Drive, Cape Girardeau, MO 63701

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    Versatile Showroom, Office, and Shop
    $12,000/Mo
    8,516 SF
    Versatile Showroom, Office, and Shop

    8,516 SF building with high visibility and multiple drive-throughs.

    229 Airport Rd, Scott City, MO 63780

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    Retail Building in High-Traffic Area
    $4 SF/Yr
    Retail Building in High-Traffic Area

    Freestanding retail building with high visibility near major retailers.

    33554 MO-25, Advance, MO 63730

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    Commercial Space For Lease
    Contact for pricing
    Commercial Space For Lease

    Commercial space available for lease at 3049 William St.

    3049 William St, Cape Girardeau, MO 63703

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    Similar Spaces for Sale in Sikeston, MO

    Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

    Historic Two-Story Commercial Building
    $190,000
    6,321 SF
    Historic Two-Story Commercial Building

    Built in 1915, this two-story property features high ceilings and downtown parking for flexible creative and service uses.

    112 Front Street, Sikeston, MO 63801

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    Downtown Sikeston Commercial Office Building
    $279,000
    4,273 SF
    Downtown Sikeston Commercial Office Building

    Commercial property with endless business opportunities in downtown Sikeston.

    202 S Kingshighway Street, Sikeston, MO 63801

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    Remodeled Commercial Building in Sikeston
    $775,000
    1.67 Acres
    Remodeled Commercial Building in Sikeston

    Remodeled commercial building suitable for single or multiple tenants.

    210 S Kingshighway Street, Sikeston, MO 63801

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    Configurable Office Building with Parking
    $250,000
    Configurable Office Building with Parking

    Versatile office building offers flexible suite configuration, multiple private entrances, and on-site parking for staff and visitors.

    713 Tanner, Sikeston, MO 63801

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    Flex-Industrial Headquarters Facility
    $449,500
    19,498 SF
    Flex-Industrial Headquarters Facility

    Multi-parcel flex facility combining office infrastructure with a full-length drive-through warehouse for operations and distribution.

    205 S New Madrid St, Sikeston, MO 63801

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    Sikeston Commercial Building Investment Opportunity
    $979,500
    11,000 SF
    Sikeston Commercial Building Investment Opportunity

    High-visibility commercial building with income and upside potential.

    808 E Wakefield Ave, Sikeston, MO 63801

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    Historic Downtown Mixed-Use Opportunity
    $299,000
    14,642 SF
    Historic Downtown Mixed-Use Opportunity

    Two-story historic building in downtown Sikeston with modern potential.

    124 E Front Street, Sikeston, MO 63801

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    Commercial Building in High Traffic
    $400,000
    7,100 SF
    Commercial Building in High Traffic

    7100 sq ft commercial building in high traffic area.

    1218 Linn St, Sikeston, MO 63801

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Office Development Land For Lease
    Contact for pricing
    4,000 SF
    Office Development Land For Lease

    2.43 acres for office development with build-to-suit opportunity.

    1323 Strawfloor Drive, Jonesboro, AR 72401

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    Collinsville Commercial Space For Lease
    $5,000/Mo
    5,000 SF
    Collinsville Commercial Space For Lease

    Versatile commercial space in Collinsville, available immediately.

    1902 Vandalia Street, Collinsville, IL 62234

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    Commercial Land For Lease
    $12,500/Mo
    Commercial Land For Lease

    Prime commercial land for lease in high-traffic Rolla location.

    626 Bishop Avenue S, Rolla, MO 65401

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    High-Traffic Commercial Land in Rolla
    $7,500/Mo
    High-Traffic Commercial Land in Rolla

    0.61 acre commercial land in high-traffic area for lease.

    704 N Bishop Avenue, Rolla, MO 65401

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    Sikeston, MO Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Sikeston, MO with 12 listings featured on our commercial real estate exchange. The current inventory includes 15,924 square feet of properties with an estimated lease value of $132 SF/Yr.

    Estimated lease rates for Office Spaces in Sikeston, MO begin at $7 SF/Yr, with an average of $14 SF/Yr and extend to $30 SF/Yr.
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