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    Sikeston, MO
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    Sikeston, MO Office Spaces for Lease

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    East Prairie, MO Charleston, MO New Madrid, MO Dexter, MO Scott City, MO
    Finished Office Suite with Kitchenette
    Updated: Jul 12
    Finished Office Suite with Kitchenette

    912 S Main Street, Sikeston, MO 63801

    $3,625/Mo
    Four finished offices within a 2020‑built strip center
    Bathroom and kitchenette with free‑standing refrigerator, table, and chairs
    Two entrances support regular public access
    Forced‑air heating and central air
    Parking lot with accessible approach and ramp
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    New Retail/Office Space Available
    Updated: Mar 2
    New Retail/Office Space Available

    E-600 N Main Street, Sikeston, MO 63801

    $1,950/Mo
    1,300 sqft
    Prime location on N. Main Street
    Exceptional traffic and visibility
    Brand new office/retail center
    1,300 square foot space available
    Ample off‑street parking
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    Flexible Office Suite
    Flexible Office Suite

    1226 Linn Street Suite C, Sikeston, MO 63801

    $1,500/Mo
    Built 1989

    Adaptable layout supports office, studio, or showroom operations.

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    Two-Level Office Building
    Two-Level Office Building

    202 S Kingshighway Street, Sikeston, MO 63801

    $4,500/Mo
    17–28 people  4,273 sqft  Built 1960
    2 private offices  1 meeting room

    The layout includes open work areas, private offices, meeting space, a break room, and access between floors by elevator.

    15 parking spaces
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    4 active listings match your search: Office for lease in Sikeston, MO. Based on your search, we've also compiled 9 Potential Opportunities for your consideration: 4 spaces in nearby cities and 5 properties for sale.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Versatile Showroom, Office, and Shop
    Versatile Showroom, Office, and Shop

    229 Airport Rd, Scott City, MO 63780

    $12,000/Mo
    8,516 sqft  Built 1988

    8,516 SF building with high visibility and multiple drive-throughs.

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    Office Suite with Pylon Signage
    Office Suite with Pylon Signage

    3065 William Street #310, Cape Girardeau, MO 63703

    Triple net (NNN)
    $1,230/Mo
    4–6 people  1,009 sqft
    Highway access

    Utility service is included, excluding voice and data.

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    Office Suite with Signage
    Office Suite with Signage

    3065 William Street #109, Cape Girardeau, MO 63703

    Triple net (NNN)
    $7,075/Mo
    200–333 people  50,000 sqft  Ground Floor

    Ground-floor office space includes utilities, with voice and data service excluded.

    Signage  Pylon highway sign
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    Charleston Retail or Office Space
    Charleston Retail or Office Space

    114 W Commercial, Charleston, MO 63834

    $6 SF/Yr
    3,028 sqft

    Retail or office space with excellent visibility and parking.

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    Similar Spaces for Sale in Sikeston, MO

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Sikeston Commercial Building Investment Opportunity
    Sikeston Commercial Building Investment Opportunity

    808 E Wakefield Ave, Sikeston, MO 63801

    $979,500
    11,000 sqft

    High-visibility commercial building with income and upside potential.

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    Flex Building with Storage Units
    Flex Building with Storage Units

    330 State Highway H, Sikeston, MO 63801

    $799,000
    2.99 AC lot

    Metal flex facility combining warehouse, office, and rear storage components with interstate access.

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    Flex-Industrial Headquarters Facility
    Flex-Industrial Headquarters Facility

    205 S New Madrid St, Sikeston, MO 63801

    $399,000
    19,498 sqft 1.00 AC lot

    Multi-parcel flex facility combining office infrastructure with a full-length drive-through warehouse for operations and distribution.

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    Remodeled Office Building
    Remodeled Office Building

    210 S Kingshighway Street, Sikeston, MO 63801

    $775,000
    1.67 AC lot

    Remodeled brick office property with multiple entrances, updated building systems, and basement space.

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    Historic Two-Story Storefront
    Historic Two-Story Storefront

    112 Front Street, Sikeston, MO 63801

    $190,000
    0.11 AC lot

    Brick construction, public water, and central air serve this downtown commercial property.

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    Sikeston, MO Office Spaces Lease Rates & Market Statistics

    Explore 4 Office Spaces for lease in Sikeston, MO on Realmo, a commercial real estate exchange covering the Sikeston area. The current inventory totals 5,573 square feet of properties.

    Asking lease rates for Office Spaces in Sikeston start at $18 SF/Yr, average $18 SF/Yr, and reach $18 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $18 SF/Yr is 21% below the Missouri state average of $22.92 SF/Yr.

    Sikeston accounts for 80% of the 5 office spaces currently available across Scott County, where a nearby market includes Scott City.

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    Featured Sikeston Real Estate Agencies

    Realmo connects you with licensed Sikeston CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Merideth Real Estate, LLC
    1101 E Malone Avenue Sikeston, MO 63801
    Phone: (573) 620-1794
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