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    Sikeston, MO Retail Space for Sale

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    Saint Louis, MO Kansas City, MO Louis, MO
    Historic Downtown Sikeston Retail Opportunity
    $275,000
    14,642 SF

    Historic Downtown Sikeston Retail Opportunity

    124 E Front Street, Sikeston, MO 63801

    Two-story retail space in high-traffic downtown Sikeston.

    • Prime downtown location with high visibility and foot traffic.
    • Value‑add opportunity with a blank canvas upstairs for customization.
    • Existing leases on the ground floor provide immediate income.
    • Historic building (built in 1915) with unique character.
    • Close proximity to retail, professional services, and restaurants.
    Updated: Feb 25
    View details
    Historical Building in Downtown Sikeston
    $269,000
    6,321 SF

    Historical Building in Downtown Sikeston

    112 Front Street, Sikeston, MO 63801

    Two-story historic building in downtown Sikeston, ideal for investors.

    • Prime downtown location with HIGH VISIBILITY.
    • Historic building BUILT IN 1915 with enduring style.
    • Abundance of parking.
    • Versatile space suitable for investor or business owner.
    • Stately HIGH CEILINGS on both levels.
    Updated: Jan 8
    View details
    Sikeston Commercial Building Investment Opportunity
    $979,500
    11,000 SF

    Sikeston Commercial Building Investment Opportunity

    High-visibility commercial building with income and upside potential.

    808 E Wakefield Ave, Sikeston, MO 63801
    View details
    Based on your search, we've compiled 148 Potential Opportunities for your consideration. Besides 3 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 139 Off-Market properties to explore as potential leads, plus 2 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Charleston Commercial Property on Highway
    $110,000
    2,121 SF

    Charleston Commercial Property on Highway

    Commercial property with existing building and highway frontage in Charleston.

    1113 E. Marshall, Charleston, MO 63834
    View details
    Prime Commercial Space on Mount Auburn
    Contact for pricing
    1,660 SF

    Prime Commercial Space on Mount Auburn

    Versatile commercial space with parking and high visibility.

    326 S. Mount Auburn, Cape Girardeau, MO 63703
    View details
    Retail/Office Space Near I-55
    Contact for pricing

    Retail/Office Space Near I-55

    Prime location near I-55 and West Park Mall.

    3065 William, Cape Girardeau, MO 63703
    View details
    Charleston, MO Commercial Investment Opportunity
    $575,000
    2,134 SF

    Charleston, MO Commercial Investment Opportunity

    High-traffic commercial property suitable for restaurant, retail, or office use.

    11 Truman St, Charleston, MO 63834
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in Growing Corridor
    $1,795,000
    2.07 Acres

    Prime Land in Growing Corridor

    2.07 acres of PUD-zoned land on State Hwy 207.

    3229 State Road 207, Elkton, FL 32033
    View details
    Commercial Land on Busy Roadway
    $750,000
    0.72 Acres

    Commercial Land on Busy Roadway

    Prime commercial land with high visibility and development potential.

    5355 TURNPIKE FEEDER ROAD, Fort Pierce, FL 34945
    View details

    Explore Off-Market Properties in Sikeston, MO

    Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    614 Virginia St

    614 Virginia St

    RETAIL STORES (PERSONAL SERVICES) • 5,096 SF
    Value Estimation by Request
    614 Virginia St, Sikeston, MO 63801-3308
    View details
    845 Malone Ave

    845 Malone Ave

    RETAIL STORES (PERSONAL SERVICES) • 27,207 SF
    Value Estimation by Request
    845 Malone Ave, Sikeston, MO 63801
    View details
    612 Matthews Ave

    612 Matthews Ave

    RETAIL STORES (PERSONAL SERVICES) • 9,134 SF
    Value Estimation by Request
    612 Matthews Ave, Sikeston, MO 63801
    View details
    136 Frnt St

    136 Frnt St

    RETAIL STORES (PERSONAL SERVICES) • 1,700 SF
    Value Estimation by Request
    136 Frnt St, Sikeston, MO 63801
    View details
    625 Greer Ave

    625 Greer Ave

    RETAIL STORES (PERSONAL SERVICES) • 2,520 SF
    Value Estimation by Request
    625 Greer Ave, Sikeston, MO 63801-3233
    View details
    101 Ranney St

    101 Ranney St

    RETAIL STORES (PERSONAL SERVICES) • 3,404 SF
    Value Estimation by Request
    101 Ranney St, Sikeston, MO 63801-4256
    View details
    Sikeston, MO 63801

    Sikeston, MO 63801

    RETAIL STORES (PERSONAL SERVICES) • 2,376 SF
    Value Estimation by Request
    Sikeston, MO 63801
    View details
    903 Malone Ave

    903 Malone Ave

    RETAIL STORES (PERSONAL SERVICES) • 2,604 SF
    Value Estimation by Request
    903 Malone Ave, Sikeston, MO 63801-2425
    View details
    616 Virginia St

    616 Virginia St

    RETAIL STORES (PERSONAL SERVICES) • 2,000 SF
    Value Estimation by Request
    616 Virginia St, Sikeston, MO 63801-3308
    View details
    603 Davis Blvd

    603 Davis Blvd

    RETAIL STORES (PERSONAL SERVICES) • 4,920 SF
    Value Estimation by Request
    603 Davis Blvd, Sikeston, MO 63801-1958
    View details
    Malone W Ave

    Malone W Ave

    RETAIL STORES (PERSONAL SERVICES) • 2,112 SF
    Value Estimation by Request
    Malone W Ave, Sikeston, MO 63801
    View details
    2105 Malone Ave, Unit 2107

    2105 Malone Ave, Unit 2107

    RETAIL STORES (PERSONAL SERVICES) • 12,777 SF
    Value Estimation by Request
    2105 Malone Ave, Sikeston, MO 63801-3733
    View details
    1592 State Hwy H H

    1592 State Hwy H H

    RETAIL STORES (PERSONAL SERVICES) • 2,604 SF
    Value Estimation by Request
    1592 State Hwy H H, Sikeston, MO 63801-8220
    View details
    Ctr E St

    Ctr E St

    RETAIL STORES (PERSONAL SERVICES) • 3,975 SF
    Value Estimation by Request
    Ctr E St, Sikeston, MO 63801
    View details
    507 Greer Ave

    507 Greer Ave

    RETAIL STORES (PERSONAL SERVICES) • 780 SF
    Value Estimation by Request
    507 Greer Ave, Sikeston, MO 63801-3023
    View details
    821 Malone Ave

    821 Malone Ave

    RETAIL STORES (PERSONAL SERVICES) • 2,538 SF
    Value Estimation by Request
    821 Malone Ave, Sikeston, MO 63801
    View details
    106 Frnt St

    106 Frnt St

    RETAIL STORES (PERSONAL SERVICES) • 4,360 SF
    Value Estimation by Request
    106 Frnt St, Sikeston, MO 63801-8592
    View details
    1401 Malone Ave

    1401 Malone Ave

    RETAIL STORES (PERSONAL SERVICES) • 31,804 SF
    Value Estimation by Request
    1401 Malone Ave, Sikeston, MO 63801-3411
    View details
    112 Frnt St

    112 Frnt St

    RETAIL STORES (PERSONAL SERVICES) • 3,380 SF
    Value Estimation by Request
    112 Frnt St, Sikeston, MO 63801
    View details
    806 Kingshighway St

    806 Kingshighway St

    RETAIL STORES (PERSONAL SERVICES) • 3,528 SF
    Value Estimation by Request
    806 Kingshighway St, Sikeston, MO 63801-5919
    View details
    516 Wilson St

    516 Wilson St

    RETAIL STORES (PERSONAL SERVICES) • 1,070 SF
    Value Estimation by Request
    516 Wilson St, Sikeston, MO 63801-1953
    View details

    Sikeston, MO Retail Space Investment Opportunities Market Analysis

    Explore 142 retail space for sale in Sikeston, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 310,446 square feet of properties for sale, with an estimated market value of $4,444,000.

    Sale prices for retail space in Sikeston, MO start at $269,000, averaging $444,400, and reaching up to $565,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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