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    Sikeston, MO
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    Sikeston, MO Retail Space for Sale

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    Miner, MO Bertrand, MO East Prairie, MO Charleston, MO Benton, MO Essex, MO Oran, MO Bloomfield, MO
    Historic Two-Story Downtown Retail Building
    Updated: Feb 25
    Historic Two-Story Downtown Retail Building

    124 E Front Street, Sikeston, MO 63801

    $275,000
    14,642 sqft 0.22 AC lot
    2‑story downtown Sikeston building originally built in 1915
    Historic brick construction with high ceilings
    Ground floor includes two existing leases
    Flat roof with forced‑air heating and central air cooling (electric)
    Utilities: natural gas available; public water and public sewer
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    Retail and Office Buildings with Drive-Through
    Updated: Oct 16, 2025
    Retail and Office Buildings with Drive-Through

    1018 Linn Street, Sikeston, MO 63801

    $550,000
    4.20 AC lot
    Two Morton buildings on site: office building ~24x48 with a 15x48 covered porch, plus shop building ~48x75
    Shop building features 2 sets of drive‑through doors and 2 walk‑through doors and 11‑foot walls
    Property includes irrigation and is served by public water; cable is available
    Utilities/amenities listed: natural gas heating and wall unit cooling
    Construction and building finishes include metal siding and concrete flooring
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    Shadow-Anchored NNN Shopping Center
    Shadow-Anchored NNN Shopping Center

    1209-1215 S Main St, Sikeston, MO 63801

    $3,750,000
    49,173 sqft

    Multi-tenant NNN shopping center anchored by nearby Walmart and Lowe’s, with retailers including Harbor Freight, CATO, and Hibbett Sports.

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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 77 Potential Opportunities for your consideration. Besides 3 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 69 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Retail Space For Sale
    Retail Space For Sale

    45 S Kingshighway, Cape Girardeau, MO 63703

    $2,900,000

    Retail property offered for sale at 45 S Kingshighway in Cape Girardeau, Missouri.

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    Commercial Building with Highway Frontage
    Commercial Building with Highway Frontage

    1113 E. Marshall, Charleston, MO 63834

    $99,900
    2,121 sqft

    Commercial building ready for renovation, featuring 300+ feet of highway frontage and 2+ acres for additional commercial use.

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    Retail Space in Charleston, MO
    Retail Space in Charleston, MO

    601 S Main Street, Charleston, MO 63834

    Contact for pricing

    Retail space available for lease in Charleston, Missouri.

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    Retail Space in Cape Girardeau
    Retail Space in Cape Girardeau

    3049 William Street, Cape Girardeau, MO 63703

    Contact for pricing

    Retail space available for lease in Cape Girardeau, Missouri.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    PUD-Zoned Commercial Land with Frontage
    PUD-Zoned Commercial Land with Frontage

    3229 State Road 207, Elkton, FL 32033

    $1,599,000
    2.07 AC lot

    2.07-acre PUD-zoned parcel on State Hwy 207 with 360 feet of frontage and an on-site renovated 2012 home.

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    Off-Market Properties in Sikeston, MO

    Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    614 Virginia St
    RETAIL STORES (PERSONAL SERVICES)

    614 Virginia St, Sikeston, MO 63801-3308

    Value Estimation by Request
    5,096 sqft 0.99 AC lot
    View details
    845 Malone Ave
    RETAIL STORES (PERSONAL SERVICES)

    845 Malone Ave, Sikeston, MO 63801

    Value Estimation by Request
    27,207 sqft 1.61 AC lot
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    612 Matthews Ave
    RETAIL STORES (PERSONAL SERVICES)

    612 Matthews Ave, Sikeston, MO 63801

    Value Estimation by Request
    9,134 sqft 0.59 AC lot
    View details
    136 Frnt St
    RETAIL STORES (PERSONAL SERVICES)

    136 Frnt St, Sikeston, MO 63801

    Value Estimation by Request
    1,700 sqft 0.06 AC lot
    View details
    625 Greer Ave
    RETAIL STORES (PERSONAL SERVICES)

    625 Greer Ave, Sikeston, MO 63801-3233

    Value Estimation by Request
    2,520 sqft 0.14 AC lot
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    101 Ranney St
    RETAIL STORES (PERSONAL SERVICES)

    101 Ranney St, Sikeston, MO 63801-4256

    Value Estimation by Request
    3,404 sqft 0.67 AC lot
    View details
    Sikeston, MO 63801
    RETAIL STORES (PERSONAL SERVICES)

    Sikeston, MO 63801

    Value Estimation by Request
    2,376 sqft 1.21 AC lot
    View details
    903 Malone Ave
    RETAIL STORES (PERSONAL SERVICES)

    903 Malone Ave, Sikeston, MO 63801-2425

    Value Estimation by Request
    2,604 sqft 0.58 AC lot
    View details
    616 Virginia St
    RETAIL STORES (PERSONAL SERVICES)

    616 Virginia St, Sikeston, MO 63801-3308

    Value Estimation by Request
    2,000 sqft 0.59 AC lot
    View details
    603 Davis Blvd
    RETAIL STORES (PERSONAL SERVICES)

    603 Davis Blvd, Sikeston, MO 63801-1958

    Value Estimation by Request
    4,920 sqft 1.45 AC lot
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    Malone W Ave
    RETAIL STORES (PERSONAL SERVICES)

    Malone W Ave, Sikeston, MO 63801

    Value Estimation by Request
    2,112 sqft 0.41 AC lot
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    2105 Malone Ave, Unit 2107
    RETAIL STORES (PERSONAL SERVICES)

    2105 Malone Ave, Sikeston, MO 63801-3733

    Unit 2107
    Value Estimation by Request
    12,777 sqft 0.89 AC lot
    View details
    1592 State Hwy H H
    RETAIL STORES (PERSONAL SERVICES)

    1592 State Hwy H H, Sikeston, MO 63801-8220

    Value Estimation by Request
    2,604 sqft 5.77 AC lot
    View details
    Ctr E St
    RETAIL STORES (PERSONAL SERVICES)

    Ctr E St, Sikeston, MO 63801

    Value Estimation by Request
    3,975 sqft 0.22 AC lot
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    507 Greer Ave
    RETAIL STORES (PERSONAL SERVICES)

    507 Greer Ave, Sikeston, MO 63801-3023

    Value Estimation by Request
    780 sqft 0.04 AC lot
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    821 Malone Ave
    RETAIL STORES (PERSONAL SERVICES)

    821 Malone Ave, Sikeston, MO 63801

    Value Estimation by Request
    2,538 sqft 1.04 AC lot
    View details
    106 Frnt St
    RETAIL STORES (PERSONAL SERVICES)

    106 Frnt St, Sikeston, MO 63801-8592

    Value Estimation by Request
    4,360 sqft 0.12 AC lot
    View details
    1401 Malone Ave
    RETAIL STORES (PERSONAL SERVICES)

    1401 Malone Ave, Sikeston, MO 63801-3411

    Value Estimation by Request
    31,804 sqft 2.53 AC lot
    View details
    112 Frnt St
    RETAIL STORES (PERSONAL SERVICES)

    112 Frnt St, Sikeston, MO 63801

    Value Estimation by Request
    3,380 sqft 0.11 AC lot
    View details
    806 Kingshighway St
    RETAIL STORES (PERSONAL SERVICES)

    806 Kingshighway St, Sikeston, MO 63801-5919

    Value Estimation by Request
    3,528 sqft 0.19 AC lot
    View details
    516 Wilson St
    RETAIL STORES (PERSONAL SERVICES)

    516 Wilson St, Sikeston, MO 63801-1953

    Value Estimation by Request
    1,070 sqft 0.13 AC lot
    View details

    Sikeston, MO Retail Space Market Trends and Statistics

    Explore 72 retail space for sale in Sikeston, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 63,815 square feet of properties for sale, with an estimated market value of $4,025,000.

    Sale prices for retail space in Sikeston, MO start at $275,000, averaging $2,012,500, and reaching up to $3,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Shopping centers 3
    Storefront properties 3
    Grocery and convenience stores 1

    Demographics Overview

    Population 22K
    Population Growth (5Y) -3.7%
    Median Household Income $55,945
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Sikeston submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63801 $557.4K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Total CRE Inventory on Market (SF)

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