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    Sikeston, MO
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    Sikeston, MO Retail Properties & Spaces for Lease

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    Tunnel Car Wash Property
    Updated: Aug 27
    Tunnel Car Wash Property

    900 S Main Street, Sikeston, MO 63801

    $4,800/Mo
    0.94 AC lot
    Operating tunnel car wash
    0.94 acres
    Built in 2016
    Brick construction
    Metal roof
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    Finished Office Suite with Kitchenette
    Updated: Sep 23, 2025
    Finished Office Suite with Kitchenette

    912 S Main Street, Sikeston, MO 63801

    $3,625/Mo
    Four finished offices within a 2020‑built strip center
    Bathroom and kitchenette with free‑standing refrigerator, table, and chairs
    Two entrances support regular public access
    Forced‑air heating and central air
    Parking lot with accessible approach and ramp
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    New Retail/Office Space Available
    New Retail/Office Space Available

    E-600 N Main Street, Sikeston, MO 63801

    $1,950/Mo
    1,300 sqft

    Prime location with high traffic and ample parking.

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    Flexible Office Suite
    Flexible Office Suite

    1226 Linn Street Suite C, Sikeston, MO 63801

    $1,500/Mo

    Adaptable layout supports office, studio, or showroom operations.

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    Neighborhood Shopping Center
    Neighborhood Shopping Center

    1103-1102 S Main Street, Sikeston, MO 63801

    $3,682/Mo

    Center features multiple entrances, off-street parking, and established Tractor Supply and Ruler Foods businesses.

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    Neighborhood Shopping Center
    Neighborhood Shopping Center

    1105-1102 S Main St, Sikeston, MO 63801

    $2,214/Mo

    The center includes Tractor Supply and Ruler Foods businesses, off-street parking, and multiple entrances.

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    Retail Space in Sikeston, MO
    Retail Space in Sikeston, MO

    925-1077 Malone Ave, Sikeston, MO

    Contact for pricing
    2,900 sqft 8.68 AC lot

    Retail space available in grocery store anchored shopping center.

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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 7 Active listings in Sikeston, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

    Retail properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Building with Drive-Through Window
    Retail Building with Drive-Through Window

    5 S Kingshighway, Cape Girardeau, MO 63703

    $8,707/Mo
    3,483 sqft 0.80 AC lot

    Drive-through retail building with off-street paved parking on C2-zoned land, adjacent to major retailers.

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    Charleston Retail or Office Space
    Charleston Retail or Office Space

    114 W Commercial, Charleston, MO 63834

    $6 SF/Yr
    3,028 sqft

    Retail or office space with excellent visibility and parking.

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    Ground-Level Storefront Space
    Ground-Level Storefront Space

    326 S Mount Auburn Rd, Cape Girardeau, MO 63703

    $1,750/Mo

    Retail space offers direct entry, on-site parking, and monument signage along Mount Auburn.

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    Shopping Center Retail Space
    Shopping Center Retail Space

    1 Villa Shopping Ctr, New Madrid, MO 63869

    $6 SF/Yr

    Three leasable units are offered within an established center serving a mix of retail, personal-service, and food users.

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    Similar Spaces for Sale in Sikeston, MO

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Historic Two-Story Storefront
    Historic Two-Story Storefront

    124 E Front St, Sikeston, MO 63801

    $275,000
    14,642 sqft

    Downtown commercial building with leased ground-floor space and an unfinished upper level.

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    Historic Two-Story Storefront
    Historic Two-Story Storefront

    124 E Front Street, Sikeston, MO 63801

    $275,000
    14,642 sqft 0.22 AC lot

    Brick commercial building with leased ground-floor space and an open upper level.

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    Historic Two-Story Storefront
    Historic Two-Story Storefront

    112 Front Street, Sikeston, MO 63801

    $190,000
    0.11 AC lot

    Brick construction, public water, and central air serve this downtown commercial property.

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    Metal-Sided Gas Station Property
    Metal-Sided Gas Station Property

    133 W Malone Avenue, Sikeston, MO 63801

    $299,000
    0.22 AC lot

    Metal-sided commercial property with documented gas station operations through 2022.

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    Shadow-Anchored NNN Shopping Center
    Shadow-Anchored NNN Shopping Center

    1209-1215 S Main St, Sikeston, MO 63801

    Contact for pricing
    49,173 sqft

    Multi-tenant NNN shopping center anchored by nearby Walmart and Lowe’s, with retailers including Harbor Freight, CATO, and Hibbett Sports.

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    Gas Station for Redevelopment
    Gas Station for Redevelopment

    133 W Malone Ave, Sikeston, MO 63801

    $299,000

    Gas station site in downtown Sikeston that served the community from 2012 to 2022.

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    Sikeston, MO Retail properties & Spaces Lease Rates & Market Statistics

    Explore 7 Retail properties & Spaces for lease in Sikeston, MO on Realmo, a commercial real estate exchange covering the Sikeston area. The current inventory totals 4,200 square feet of properties.

    Asking lease rates for Retail properties & Spaces in Sikeston start at $18 SF/Yr, average $18 SF/Yr, and reach $18 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $18 SF/Yr is 16% above the Missouri state average of $15.50 SF/Yr.

    Sikeston accounts for 88% of the 8 retail properties & spaces currently available across Scott County, where a nearby market includes Scott City.

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