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    Sikeston, MO Commercial Land for Sale

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    Bertrand, MO Matthews, MO East Prairie, MO
    12 results
    Commercial Land in Sikeston, MO
    $400,000
    2.63 Acres

    Commercial Land in Sikeston, MO

    109 Stallcup Drive, Sikeston, MO 63801

    2.63 acres in booming retail and hospitality area.

    • Premium commercial location in Sikeston's retail and hospitality area.
    • Over 2.5 acres of commercial property.
    • Close proximity to Wal‑Mart Supercenter, new hotels, shopping, and restaurants.
    • Half mile to the intersection of US Highways 60 & 61.
    • Level exterior features.
    Updated: Mar 13
    View details
    Commercial Land on Highway 61
    $144,000
    1.01 Acres

    Commercial Land on Highway 61

    103 Grove Estates, Sikeston, MO 63801

    Commercial land on high-traffic route near Sikeston Industrial Park.

    • High‑traffic location on Highway 61, ideal for business visibility.
    • Zoned C‑1 Neighborhood Shopping District, suitable for retail and personal services.
    • Proximity to Sikeston Industrial Park and Southeast Missouri State University campus.
    • Adjacent to Greenbriar and Fairfield Subdivisions, providing a built‑in customer base.
    • Perfect for office, medical, and professional services.
    Updated: Oct 7, 2025
    View details
    Commercial Land in Retail Area
    $500,000
    1.05 Acres

    Commercial Land in Retail Area

    1.05 acres of commercial land for development in Sikeston.

    1209 Lawrence, Sikeston, MO 63801
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    Commercial Land in Sikeston, MO
    $500,000
    1.24 Acres

    Commercial Land in Sikeston, MO

    1.24 acre commercial lot near apartments and retail.

    1201 Lawrence, Sikeston, MO 63801
    View details
    Commercial Land Ready For Development
    $199,000
    2.00 Acres

    Commercial Land Ready For Development

    Two-acre commercial lot available for development in Sikeston, Missouri.

    224 S Interstate Drive, Sikeston, MO 63801
    View details
    Commercial Land in Sikeston, MO
    $195,000
    0.72 Acres

    Commercial Land in Sikeston, MO

    Vacant, level commercial lot available in Sikeston, Missouri.

    116 Hospitality Drive, Sikeston, MO 63801
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    Prime Land for Commercial Development
    $3,960,000
    88.00 Acres

    Prime Land for Commercial Development

    88 acres at I-55 and I-57, Sikeston, MO.

    0 Ables Road, Sikeston, MO 63801
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    Sikeston Commercial Land Available
    Contact for pricing

    Sikeston Commercial Land Available

    Commercial land available in Sikeston, Missouri.

    1240 S Main Street, Sikeston, MO 63801
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    Prime Land for Commercial Development
    $3,960,000

    Prime Land for Commercial Development

    Commercial land available at I-55 and I-57 interchange.

    Ables Road, Sikeston, MO 63801
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    Commercial Land on South Main
    Contact for pricing
    0.31 Acres

    Commercial Land on South Main

    Highly visible land parcel suitable for retail development.

    1240 S Main St, Sikeston, MO
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    Commercial Land in Retail Area
    $500,000
    1.05 Acres

    Commercial Land in Retail Area

    1.05 acre commercial land for development in Sikeston, Missouri.

    1209 Lawrence, Sikeston, MO 63801
    View details
    Commercial Land on Stallcup Drive
    $500,000
    1.24 Acres

    Commercial Land on Stallcup Drive

    1.24 acre commercial land for sale near retail.

    1201 Lawrence, Sikeston, MO 63801
    View details
    Based on your search, we've compiled 64 Potential Opportunities for your consideration. Besides 12 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 48 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    I-55 Land Parcel Opportunity
    $395,000
    5.00 Acres

    I-55 Land Parcel Opportunity

    5 acre parcel suitable for truck stop or fuel station.

    337 State Highway P, New Madrid, MO 63869
    View details
    Commercial Land in Dexter, MO
    $2,000,000
    2.96 Acres

    Commercial Land in Dexter, MO

    Commercial property suitable for business, subdivision possible.

    0 W Bus Hwy 60, Dexter, MO 63841
    View details
    I-55 Frontage Development Opportunity
    $395,000
    5.00 Acres

    I-55 Frontage Development Opportunity

    5 acre commercial land parcel with I-55 frontage.

    337 State Hwy P, New Madrid, MO 63869
    View details
    Commercial Land on N Outer
    $459,900

    Commercial Land on N Outer

    Commercial land parcel located on N Outer Road.

    16335 N Outer Road, Dexter, MO 63841
    View details

    Off-Market Properties in Sikeston, MO

    Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    538 County Line Rd

    538 County Line Rd

    VACANT COMMERCIAL LAND • 27.30 Acres
    Value Estimation by Request
    538 County Line Rd, Sikeston, MO 63801
    View details
    1157 Main St

    1157 Main St

    VACANT COMMERCIAL LAND • 0.93 Acres
    Value Estimation by Request
    1157 Main St, Sikeston, MO 63801-3102
    View details
    1239 Commerce Dr

    1239 Commerce Dr

    VACANT COMMERCIAL LAND • 3.81 Acres
    Value Estimation by Request
    1239 Commerce Dr, Sikeston, MO 63801-9311
    View details
    1213 Cinema Dr

    1213 Cinema Dr

    VACANT COMMERCIAL LAND • 0.52 Acres
    Value Estimation by Request
    1213 Cinema Dr, Sikeston, MO 63801
    View details
    Cinema Dr

    Cinema Dr

    VACANT COMMERCIAL LAND • 1.24 Acres
    Value Estimation by Request
    Cinema Dr, Sikeston, MO 63801
    View details
    99 Stallcup Dr

    99 Stallcup Dr

    VACANT COMMERCIAL LAND
    Value Estimation by Request
    99 Stallcup Dr, Sikeston, MO 63801-9383
    View details
    807 County Line Rd

    807 County Line Rd

    VACANT COMMERCIAL LAND • 13.70 Acres
    Value Estimation by Request
    807 County Line Rd, Sikeston, MO 63801
    View details
    Harlene St

    Harlene St

    VACANT COMMERCIAL LAND • 5.13 Acres
    Value Estimation by Request
    Harlene St, Sikeston, MO 63801
    View details
    Us Hwy 62

    Us Hwy 62

    VACANT COMMERCIAL LAND • 67.00 Acres
    Value Estimation by Request
    Us Hwy 62, Sikeston, MO 63801
    View details
    Stallcup Dr

    Stallcup Dr

    VACANT COMMERCIAL LAND • 2.65 Acres
    Value Estimation by Request
    Stallcup Dr, Sikeston, MO 63801
    View details
    Stallcup Dr

    Stallcup Dr

    VACANT COMMERCIAL LAND • 1.27 Acres
    Value Estimation by Request
    Stallcup Dr, Sikeston, MO 63801
    View details
    1168 Stallcup Dr

    1168 Stallcup Dr

    VACANT COMMERCIAL LAND • 2.93 Acres
    Value Estimation by Request
    1168 Stallcup Dr, Sikeston, MO 63801
    View details

    Sikeston, MO Commercial Land Investment Opportunities Market Analysis

    Explore 60 commercial land for sale in Sikeston, MO, showcased through 12 active listings on our real estate platform. These investment opportunities span a total of 0 square feet of properties for sale, with an estimated market value of $10,858,000.

    Sale prices for commercial lots in Sikeston, MO start at $0.00, averaging $904,833, and reaching up to $3,960,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Operating Costs & Financing

    Average Loan-to-Value 65.0%

    Leading Commercial Asset Segments

    Residential land & home lots 45
    Commercial land 12
    Industrial land 3

    Sikeston Demographics Overview

    Population 22K
    Population Growth (5Y) -3.7%
    Median Household Income $55,945
    College Educated 31.9%

    High-Yield Neighborhoods for Strategic Investment

    Identify Sikeston submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    63801 $1.1M

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