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    Sikeston, MO Commercial Land for Sale

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    Miner, MO Bertrand, MO East Prairie, MO
    12 listings
    Prime Land Off I-55
    $1,200,000
    22.84 Acres
    Prime Land Off I-55

    2338 S Acres Drive, Sikeston, MO 63801

    22+ acre vacant land with high visibility and traffic.
    • Prime location off I‑55 (Exit 69) with high traffic and exceptional visibility.
    • Over 22 acres of vacant ground suitable for development.
    • Effortless ingress/egress for customers and employees.
    • Surrounded by established retailers and a strong daytime population.
    • Ideal for retail, restaurant/QSR, service, medical, or professional uses.
    Updated: May 26
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    Commercial Land on Highway 61
    $144,000
    1.01 Acres
    Commercial Land on Highway 61

    103 Grove Estates, Sikeston, MO 63801

    Commercial land on high-traffic route near Sikeston Industrial Park.
    • High‑traffic location on Highway 61, ideal for business visibility.
    • Zoned C‑1 Neighborhood Shopping District, suitable for retail and personal services.
    • Proximity to Sikeston Industrial Park and Southeast Missouri State University campus.
    • Adjacent to Greenbriar and Fairfield Subdivisions, providing a built‑in customer base.
    • Perfect for office, medical, and professional services.
    Updated: Oct 7, 2025
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    Commercial Land in Sikeston, MO
    $400,000
    2.63 Acres
    Commercial Land in Sikeston, MO

    2.63 acres in booming retail and hospitality area.

    109 Stallcup Drive, Sikeston, MO 63801

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    Prime Land I-55 Exit 69
    $1,200,000
    994,910 SF
    Prime Land I-55 Exit 69

    High-traffic vacant land suitable for retail or restaurant development.

    2338 South Acres Drive, Sikeston, MO 63801

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    Commercial Land in Retail Area
    $500,000
    1.05 Acres
    Commercial Land in Retail Area

    1.05 acres of commercial land for development in Sikeston.

    1209 Lawrence, Sikeston, MO 63801

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    Commercial Land in Sikeston, MO
    $500,000
    1.24 Acres
    Commercial Land in Sikeston, MO

    1.24 acre commercial lot near apartments and retail.

    1201 Lawrence, Sikeston, MO 63801

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    Commercial Land Ready For Development
    $199,000
    2.00 Acres
    Commercial Land Ready For Development

    Two-acre commercial lot available for development in Sikeston, Missouri.

    224 S Interstate Drive, Sikeston, MO 63801

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    Prime Land for Commercial Development
    $3,960,000
    88.00 Acres
    Prime Land for Commercial Development

    88 acres at I-55 and I-57, Sikeston, MO.

    0 Ables Road, Sikeston, MO 63801

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    Commercial Land in Sikeston, MO
    $195,000
    0.72 Acres
    Commercial Land in Sikeston, MO

    Vacant, level commercial lot available in Sikeston, Missouri.

    116 Hospitality Drive, Sikeston, MO 63801

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    Sikeston Commercial Land Available
    Contact for pricing
    Sikeston Commercial Land Available

    Commercial land available in Sikeston, Missouri.

    1240 S Main Street, Sikeston, MO 63801

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    Prime Land for Commercial Development
    $3,960,000
    Prime Land for Commercial Development

    Commercial land available at I-55 and I-57 interchange.

    Ables Road, Sikeston, MO 63801

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    Commercial Land in Retail Area
    $500,000
    1.05 Acres
    Commercial Land in Retail Area

    1.05 acre commercial land for development in Sikeston, Missouri.

    1209 Lawrence, Sikeston, MO 63801

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    Based on your search, we've compiled 64 Potential Opportunities for your consideration. Besides 12 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 48 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Charleston, MO Commercial Land Opportunity
    $950,000
    11.04 Acres
    Charleston, MO Commercial Land Opportunity

    11.04 acre commercial land with high visibility and access.

    3,5,7,9 Charleston Plaza, Charleston, MO 63834

    View details
    I-55 Land Parcel Opportunity
    $395,000
    5.00 Acres
    I-55 Land Parcel Opportunity

    5 acre parcel suitable for truck stop or fuel station.

    337 State Highway P, New Madrid, MO 63869

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    High-Frontage Retail or Office Building
    $99,900
    2,121 SF
    High-Frontage Retail or Office Building

    Commercial building on a highway-frontage site with space for retail or office redevelopment.

    1113 E. Marshall, Charleston, MO 63834

    View details
    I-55 Frontage Development Opportunity
    $395,000
    5.00 Acres
    I-55 Frontage Development Opportunity

    5 acre commercial land parcel with I-55 frontage.

    337 State Hwy P, New Madrid, MO 63869

    View details

    Off-Market Properties in Sikeston, MO

    Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    538 County Line Rd
    VACANT COMMERCIAL LAND
    Lot: 27.30 Acres
    Value Estimation by Request

    538 County Line Rd, Sikeston, MO 63801

    View details
    1157 Main St
    VACANT COMMERCIAL LAND
    Lot: 0.93 Acres
    Value Estimation by Request

    1157 Main St, Sikeston, MO 63801-3102

    View details
    1239 Commerce Dr
    VACANT COMMERCIAL LAND
    Lot: 3.81 Acres
    Value Estimation by Request

    1239 Commerce Dr, Sikeston, MO 63801-9311

    View details
    1213 Cinema Dr
    VACANT COMMERCIAL LAND
    Lot: 0.52 Acres
    Value Estimation by Request

    1213 Cinema Dr, Sikeston, MO 63801

    View details
    Cinema Dr
    VACANT COMMERCIAL LAND
    Lot: 1.24 Acres
    Value Estimation by Request

    Cinema Dr, Sikeston, MO 63801

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    99 Stallcup Dr
    VACANT COMMERCIAL LAND
    Value Estimation by Request

    99 Stallcup Dr, Sikeston, MO 63801-9383

    View details
    807 County Line Rd
    VACANT COMMERCIAL LAND
    Lot: 13.70 Acres
    Value Estimation by Request

    807 County Line Rd, Sikeston, MO 63801

    View details
    Harlene St
    VACANT COMMERCIAL LAND
    Lot: 5.13 Acres
    Value Estimation by Request

    Harlene St, Sikeston, MO 63801

    View details
    Us Hwy 62
    VACANT COMMERCIAL LAND
    Lot: 67.00 Acres
    Value Estimation by Request

    Us Hwy 62, Sikeston, MO 63801

    View details
    Stallcup Dr
    VACANT COMMERCIAL LAND
    Lot: 2.65 Acres
    Value Estimation by Request

    Stallcup Dr, Sikeston, MO 63801

    View details
    Stallcup Dr
    VACANT COMMERCIAL LAND
    Lot: 1.27 Acres
    Value Estimation by Request

    Stallcup Dr, Sikeston, MO 63801

    View details
    1168 Stallcup Dr
    VACANT COMMERCIAL LAND
    Lot: 2.93 Acres
    Value Estimation by Request

    1168 Stallcup Dr, Sikeston, MO 63801

    View details

    Sikeston, MO Commercial Land Market Trends and Statistics

    Explore 60 commercial land for sale in Sikeston, MO, showcased through 12 active listings on our real estate platform. These investment opportunities span a total of 994,910 square feet of properties for sale, with an estimated market value of $1,200,000.

    Sale prices for commercial lots in Sikeston, MO start at $1,200,000, averaging $1,200,000, and reaching up to $1,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Residential land & home lots 45
    Commercial land 12
    Industrial land 2

    Demographics Overview

    Population 22K
    Population Growth (5Y) -3.7%
    Median Household Income $55,945
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Sikeston submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63801 $1.2M

    Taxes & Financing

    Average Loan-to-Value 65.0%

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