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    Sikeston, MO Mixed-use Properties for Sale

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    Miner, MO Bertrand, MO East Prairie, MO
    Historic Downtown Mixed-Use Opportunity
    $299,000
    14,642 SF
    Historic Downtown Mixed-Use Opportunity

    124 E Front Street, Sikeston, MO 63801

    Two-story historic building in downtown Sikeston with modern potential.
    • Prime downtown location in a high‑visibility, high‑foot‑traffic area
    • Value‑add opportunity with a blank canvas upstairs for customization
    • Existing leases on the ground floor provide immediate income
    • Historic building (built in 1915) with unique character
    • Close proximity to retail, professional services, and restaurants
    Updated: Mar 12
    View details
    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 1 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 5 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Remodeled Commercial Property in Charleston
    $350,000
    4,173 SF
    Remodeled Commercial Property in Charleston

    Turnkey commercial property with residential zoning in prime location.

    506 S Main Street, Charleston, MO 63834

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    Cape Girardeau Mixed-Use Property
    $1,125,000
    4,000 SF
    Cape Girardeau Mixed-Use Property

    Mixed-use property with shop and residential rental income.

    241 County Road 226, Cape Girardeau, MO 63701

    View details
    Broadway Commercial Space with Apartment
    $280,000
    2,900 SF
    Broadway Commercial Space with Apartment

    Versatile commercial space with remodeled apartment in prime location.

    520 Broadway Street, Cape Girardeau, MO 63701

    View details
    Remodeled Mixed-Use Property For Sale
    $425,000
    4,173 SF
    Remodeled Mixed-Use Property For Sale

    Turnkey, remodeled mixed-use property with commercial/residential zoning.

    506 S Main Street, Charleston, MO 63834

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    9-Acre Development Opportunity in Union
    $220,500
    9.00 Acres
    9-Acre Development Opportunity in Union

    Undeveloped 9-acre tract near I-69 interchange, ideal for development.

    Reese Alexander Road, Union City, TN 38261

    View details
    Highway Frontage Land For Sale
    $149,000
    15.00 Acres
    Highway Frontage Land For Sale

    15 acre commercial land with highway frontage and county water.

    0 SW of US Hwy 67, Neelyville, MO 63901

    View details
    Prime Corner Lot For Sale
    $150,000
    1.09 Acres
    Prime Corner Lot For Sale

    1.09-acre corner lot near Walmart and I-69.

    Middle Road, Fulton, KY 42041

    View details
    Paducah Commercial Land For Sale
    $825,000
    4.10 Acres
    Paducah Commercial Land For Sale

    4.10-acre commercial land in a thriving retail corridor.

    5269 Hinkleville Road, Paducah, KY 42001

    View details

    Off-Market Properties in Sikeston, MO

    Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    State Hwy Aa
    STORE/OFFICE (MIXED USE)
    4,100 SF Lot: 0.21 Acres
    Value Estimation by Request

    State Hwy Aa, Sikeston, MO 63801

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    Main St
    Mixed-use properties
    Lot: 2.14 Acres
    Value Estimation by Request
    Main St

    0 Main St, Sikeston, MO 63801

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    604 Smith Ave
    STORE/OFFICE (MIXED USE)
    2,160 SF Lot: 0.13 Acres
    Value Estimation by Request

    604 Smith Ave, Sikeston, MO 63801-5250

    View details
    116 Kingshighway St
    STORES & APARTMENTS
    4,720 SF Lot: 0.19 Acres
    Value Estimation by Request

    116 Kingshighway St, Sikeston, MO 63801-4139

    View details
    132 Frnt St
    STORES & APARTMENTS
    4,920 SF Lot: 0.17 Acres
    Value Estimation by Request

    132 Frnt St, Sikeston, MO 63801

    View details

    Sikeston, MO Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 6 mixed-use properties for sale in Sikeston, MO on our real estate platform. These investment opportunities span a total of 14,642 square feet of properties for sale, with an estimated market value of $299,000.

    Sale prices for multi use buildings in Sikeston, MO start at $299,000, averaging $299,000, and reaching up to $299,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Property Size Breakdown

    The majority of commercial real estate listings in Sikeston fall within the 25,000 to 50,000 square foot range.

    Demographics Overview

    Population 22K
    Population Growth (5Y) -3.7%
    Median Household Income $55,945
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Sikeston submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    63801 $299K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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