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    Sikeston, MO Mixed-use Properties for Sale

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    Saint Louis, MO Kansas City, MO Louis, MO
    Historic Downtown Mixed-Use Opportunity
    $299,000
    14,642 SF

    Historic Downtown Mixed-Use Opportunity

    124 E Front Street, Sikeston, MO 63801

    Two-story historic building in downtown Sikeston with modern potential.

    • Prime downtown location in a high‑visibility, high‑foot‑traffic area
    • Value‑add opportunity with a blank canvas upstairs for customization
    • Existing leases on the ground floor provide immediate income
    • Historic building (built in 1915) with unique character
    • Close proximity to retail, professional services, and restaurants
    Updated: Mar 12
    View details
    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 1 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 5 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Commercial Property For Sale
    $295,000
    2,920 SF

    Versatile Commercial Property For Sale

    High-visibility commercial property with flexible layout and spacious attached warehouse.

    225 Clark Avenue, Cape Girardeau, MO 63701
    View details
    Remodeled Commercial Property in Charleston
    $350,000
    4,173 SF

    Remodeled Commercial Property in Charleston

    Turnkey commercial property with residential zoning in prime location.

    506 S Main Street, Charleston, MO 63834
    View details
    Broadway Commercial Space with Apartment
    $280,000
    5,100 SF

    Broadway Commercial Space with Apartment

    Versatile investment opportunity with remodeled apartment and commercial space.

    520 Broadway Street, Cape Girardeau, MO 63701
    View details
    Remodeled Mixed-Use Property For Sale
    $425,000
    4,173 SF

    Remodeled Mixed-Use Property For Sale

    Turnkey, remodeled mixed-use property with commercial/residential zoning.

    506 S Main Street, Charleston, MO 63834
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    9-Acre Development Opportunity in Union
    $220,500
    9.00 Acres

    9-Acre Development Opportunity in Union

    Undeveloped 9-acre tract near I-69 interchange, ideal for development.

    Reese Alexander Road, Union City, TN 38261
    View details
    Prime Corner Lot Near Walmart
    $150,000
    1.09 Acres

    Prime Corner Lot Near Walmart

    1.09-acre commercial lot near Walmart, I-69, and restaurants.

    0000 Middle Road, Fulton, KY 42041
    View details
    Paducah Commercial Land For Sale
    $825,000
    4.10 Acres

    Paducah Commercial Land For Sale

    4.10-acre commercial land in a thriving retail corridor.

    5269 Hinkleville Road, Paducah, KY 42001
    View details
    Prime Commercial Development Opportunity
    $825,000
    12.00 Acres

    Prime Commercial Development Opportunity

    12-acre commercial land near Strawberry Hills development.

    4231 Hansen Road, Paducah, KY 42001
    View details

    Explore Off-Market Properties in Sikeston, MO

    Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    State Hwy Aa

    State Hwy Aa

    STORE/OFFICE (MIXED USE) • 4,100 SF
    Value Estimation by Request
    State Hwy Aa, Sikeston, MO 63801
    View details
    Main St

    Main St

    Mixed-use properties • 2.14 Acres
    Value Estimation by Request
    0 Main St, Sikeston, MO 63801
    View details
    604 Smith Ave

    604 Smith Ave

    STORE/OFFICE (MIXED USE) • 2,160 SF
    Value Estimation by Request
    604 Smith Ave, Sikeston, MO 63801-5250
    View details
    116 Kingshighway St

    116 Kingshighway St

    STORES & APARTMENTS • 4,720 SF
    Value Estimation by Request
    116 Kingshighway St, Sikeston, MO 63801-4139
    View details
    132 Frnt St

    132 Frnt St

    STORES & APARTMENTS • 4,920 SF
    Value Estimation by Request
    132 Frnt St, Sikeston, MO 63801
    View details

    Sikeston, MO Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 6 mixed-use properties for sale in Sikeston, MO on our real estate platform. These investment opportunities span a total of 123,572 square feet of properties for sale, with an estimated market value of $299,000.

    Sale prices for multi use buildings in Sikeston, MO start at $0.00, averaging $49,833, and reaching up to $299,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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