Mixed-Use

Sikeston, MO Mixed-use Properties for Sale

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Mixed-Use Property with Duplex
Updated: May 21, 2025
Mixed-Use Property with Duplex

101-103 Donald Fulton Dr, Sikeston, MO 63801

$290,000
4,244 sqft 1.22 AC lot
3,124‑square‑foot commercial building with prior daycare, beauty shop, and barber shop uses
Duplex includes two 1‑bedroom, 1‑bath units totaling 1,120 square feet
Both duplex units are rented on a month‑to‑month basis
Additional 900‑square‑foot storage building
1.22‑acre site with concrete parking
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Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 1 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 5 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Mixed-Use Property with Bar & Grill
Mixed-Use Property with Bar & Grill

10 S Spanish Street, Cape Girardeau, MO 63703

$2,500,000
0.65 AC lot

The sale combines an operating hospitality business with residential and commercial spaces.

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Remodeled Mixed-Use Property
Remodeled Mixed-Use Property

506 S Main St, Charleston, MO 63834

$350,000
4,173 sqft

Commercial/residential zoning supports flexible occupancy within a substantially updated building.

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Updated Mixed-Use Building
Updated Mixed-Use Building

506 S Main Street, Charleston, MO 63834

$350,000
4,173 sqft 0.23 AC lot

Brick commercial property with refreshed building systems and zoning supporting commercial and residential use.

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Three-Unit Mixed-Use Property
Three-Unit Mixed-Use Property

401 S West End Boulevard, Cape Girardeau, MO 63703

$299,000
0.15 AC lot

Brick construction combines residential and commercial occupancy with multiple lease arrangements.

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Off-Market Properties in Sikeston, MO

Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

State Hwy Aa
STORE/OFFICE (MIXED USE)

State Hwy Aa, Sikeston, MO 63801

Estimated value: by Request
4,100 sqft 0.21 AC lot
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Main St
Mixed-use properties

0 Main St, Sikeston, MO 63801

Estimated value: by Request
2.14 AC lot
View details
604 Smith Ave
STORE/OFFICE (MIXED USE)

604 Smith Ave, Sikeston, MO 63801-5250

Estimated value: by Request
2,160 sqft 0.13 AC lot
View details
116 Kingshighway St
STORES & APARTMENTS

116 Kingshighway St, Sikeston, MO 63801-4139

Estimated value: by Request
4,720 sqft 0.19 AC lot
View details
132 Frnt St
STORES & APARTMENTS

132 Frnt St, Sikeston, MO 63801

Estimated value: by Request
4,920 sqft 0.17 AC lot
View details

Sikeston, MO Mixed-Use Properties Market Trends and Statistics

Explore 6 mixed-use properties for sale in Sikeston, MO on our real estate platform. These investment opportunities span a total of 4,244 square feet of properties for sale, with an estimated market value of $290,000.

Sale prices for multi use buildings in Sikeston, MO average $290,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 22K
Population Growth (5Y) -3.7%
Median Household Income $55,945
College Educated 31.9%

High-Yield Neighborhoods for Investment

Identify Sikeston submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
63801 $290K

Taxes & Financing

Average Loan-to-Value 65.0%

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in Sikeston fall within the 25,000 to 50,000 square foot range.

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