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    Roanoke, VA Medical Office Space for Lease

    12 results
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    Brambleton Avenue Commercial Space Available
    $22 SF/Yr
    1,700 SF

    Brambleton Avenue Commercial Space Available

    5002 Brambleton Ave, Roanoke, VA 24018

    1,700 SF space suitable for medical, office, or retail.

    • High‑traffic location on Brambleton Ave with 26,000 vehicles per day
    • Versatile 1,700 SF space suitable for medical, professional office, or retail use
    • Previously a dental office, featuring 4 operatories, reception area, 2 bathrooms, office, sterilization area, and break room
    • Close proximity to the new Publix site and established neighborhoods
    • Located in a desirable area of southwest county
    Updated: Mar 6
    View details
    Prime Commercial Space in Roanoke
    $12 SF/Yr
    10,923 SF

    Prime Commercial Space in Roanoke

    2727 Franklin Rd, Roanoke, VA

    Modern, versatile office space in Roanoke's Innovation Corridor.

    • Prime location in Roanoke's Innovation Corridor, near medical, research, and professional facilities.
    • Excellent connectivity with direct access to I‑581 and U.S. 220.
    • High visibility on Franklin Road with approximately 28,000 AADT.
    • Ample parking for clients and employees.
    • Modern and versatile space with customizable floor plans.
    Updated: Jul 29, 2025
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    Retail Space Near Valley View
    Contact for pricing
    6,900 SF

    Retail Space Near Valley View

    Endcap space for sale or lease near Valley View Mall.

    1920 Valley View Blvd NW, Roanoke, VA 24012
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    Roanoke Office and Medical Space
    $16 SF/Yr
    1,152 SF

    Roanoke Office and Medical Space

    Office and medical space in Roanoke's growth corridor.

    1315 2nd St SW, Roanoke, VA
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    New Class A Office Space
    Contact for pricing
    6,500 SF

    New Class A Office Space

    Newly constructed medical/professional office space for lease in Roanoke County.

    3090 Electric Rd, Roanoke, VA
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    First Floor Office Suite
    $14 SF/Yr
    3,000 SF

    First Floor Office Suite

    Office suite for rent with high visibility and ample parking.

    5304 Indian Grave Rd, Roanoke, VA
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    Medical/Professional Office Space Available
    $19 SF/Yr
    3,000 SF

    Medical/Professional Office Space Available

    3,000 SF medical/professional office space for lease.

    375 Hershberger Rd, Roanoke, VA
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    Office Space in Prime Location
    $15 SF/Yr
    2,023 SF

    Office Space in Prime Location

    Ready-to-use office suites in a demographically affluent Roanoke neighborhood.

    3241 Electric Rd, Roanoke, VA
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    Roanoke Office Space For Lease
    $11 SF/Yr
    1,912 SF

    Roanoke Office Space For Lease

    Ready-to-use office suites in a well-located Roanoke office park.

    3247 Electric Rd, Roanoke, VA
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    Professional Office Space For Lease
    $12 SF/Yr
    957 SF

    Professional Office Space For Lease

    Customizable office suites in affluent Roanoke neighborhood, recently renovated.

    3243 Electric Rd, Roanoke, VA
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    Office or Medical Space Available
    $17 SF/Yr
    1,800 SF

    Office or Medical Space Available

    Office or medical space for lease in Roanoke, Virginia.

    4633 Brambleton Ave, Roanoke, VA
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    Office Building Near Valley View
    Contact for pricing

    Office Building Near Valley View

    Office building near Valley View Mall with ample parking.

    5060 Valley View Blvd NW, Roanoke, VA 24012
    View details
    Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 12 Active listings in Roanoke, VA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Move-in Ready Medical Office Condo
    $1.00 SF/Yr

    Move-in Ready Medical Office Condo

    Former dental/medical office space with existing infrastructure in Staunton, VA.

    1557 COMMERCE AVE, Staunton, VA 24401
    View details
    Move-in Ready Medical Office Condo
    $1.00 SF/Yr

    Move-in Ready Medical Office Condo

    Former dental/medical office space with existing infrastructure.

    1557 COMMERCE AVE, Staunton, VA 24401
    View details
    North Greensboro Office/Medical Space
    $14 SF/Yr
    1,760 SF

    North Greensboro Office/Medical Space

    Office or medical space for lease in north Greensboro.

    2704-2722 N Church St, Greensboro, NC
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    Medical Office Space Available
    Contact for pricing

    Medical Office Space Available

    Medical office space for rent with easy highway access.

    3200 Horse Pen Creek Rd, Greensboro, NC 27410
    View details

    Explore Similar Spaces for Sale in Roanoke, VA

    Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

    Updated Commercial Space with Parking
    $299,950
    0.22 Acres

    Updated Commercial Space with Parking

    Remodeled commercial space with parking near airport and retail.

    5111 Airport Rd NW, Roanoke, VA 24012
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    Roanoke Medical Office For Sale
    $1,300,000
    0.44 Acres

    Roanoke Medical Office For Sale

    Professional office space in South Roanoke location near hospitals.

    2118 Rosalind Ave SW, Roanoke, VA 24014
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    Medical/Office Building Near Valley View
    Contact for pricing
    60,055 SF

    Medical/Office Building Near Valley View

    60,055 RSF medical/office building adjacent to Valley View Mall.

    4910 Valley View Boulevard Northwest, Roanoke, VA 24012
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    Medical/Office Building in Roanoke County
    $1,250,000
    5,678 SF

    Medical/Office Building in Roanoke County

    5,678 SF medical/office building on 1.15 acre site.

    5303 Indian Grave Rd, Roanoke, VA
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    South Roanoke Office/Medical Opportunity
    $1,750,000
    6,631 SF

    South Roanoke Office/Medical Opportunity

    Office or medical building near Carilion Roanoke Memorial Hospital.

    301 McClanahan St - SW, Roanoke, VA
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    South Roanoke Office/Medical Building For Sale
    $1,750,000
    6,631 SF

    South Roanoke Office/Medical Building For Sale

    Office or medical building in South Roanoke with parking.

    301 McClanahan St SW, Roanoke, VA 24014
    View details
    Medical Office Building For Rent
    $1,150,000
    3,391 SF

    Medical Office Building For Rent

    Southwest County medical office building with two suites available.

    5100-5104 Bernard Dr, Roanoke, VA
    View details
    Roanoke Office Building with Views
    $1,350,000
    10,129 SF

    Roanoke Office Building with Views

    10,129 SF office building with valley views for sale.

    7851-7857 Enon Dr, Roanoke, VA
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in Upper St Clair
    $50,000

    Prime Land in Upper St Clair

    Commercial land for lease in Upper St Clair, PA.

    2585 Maple Lane, Upper St Clair, PA 15241
    View details
    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details
    Prime Commercial Lot For Rent
    $7,500 /Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details

    Roanoke, VA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Roanoke, VA with 12 listings featured on our commercial real estate exchange. The current inventory includes 475,805,880 square feet of properties with an estimated lease value of $12 SF/Yr.

    Estimated lease rates for Medical Office Space in Roanoke, VA begin at $12 SF/Yr, with an average of $12 SF/Yr and extend to $12 SF/Yr.
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    Popular Searches in Roanoke, VA

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    Most Searched ZIP Codes in Roanoke, VA

    • 24012
    • 24018

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