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    Lee County, FL Live-work Space for Sale

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    Fort Myers Live/Work Opportunity
    $3,795,000
    1.06 Acres

    Fort Myers Live/Work Opportunity

    3131 E Riverside Dr, Fort Myers, FL 33916

    Fenced property with security, new roof, and hurricane windows.

    • River Front property with waterfront office sections.
    • Previously approved for PUD high‑rise development by the City.
    • New 175mph hurricane resistant windows with lifetime warranty.
    • New Firestone TPO roof with remaining multi‑year warranty.
    • Completely fenced‑in with security lighting and electronic security coded gate access.
    Updated: Dec 10, 2025
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    Prime Sanibel Commercial Landmark
    $3,295,000
    0.49 Acres

    Prime Sanibel Commercial Landmark

    1446 Periwinkle Way, Sanibel, FL 33957

    Versatile property on Periwinkle Way with business, investment, and lifestyle potential.

    • Prime Periwinkle Way frontage with 150 feet in a high‑traffic commercial corridor.
    • Versatile property featuring a retail building (2,358 sq ft), a residence (2,390 sq ft, 4 bed/2 bath), and a workshop with apartment.
    • Significant income potential through rental of the apartment and/or commercial space.
    • Flexible usage options: retail, office, wellness center, or mixed commercial/residential.
    • Established landmark site with a history of success as the Island Trading Post.
    Updated: Dec 10, 2025
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    Based on your search, we've compiled 4 Potential Opportunities for your consideration. Besides 2 Active listings in Lee County, FL, we suggest exploring several alternatives: plus 2 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Gulfside Corner Parcel
    $1,275,000
    0.11 Acres

    Prime Gulfside Corner Parcel

    Corner parcel near rebuilt Neptune Resort and beach access.

    2330 Estero Blvd, Fort Myers Beach, FL 33931
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    Waterfront Lot in Matlacha, FL
    $474,900
    0.19 Acres

    Waterfront Lot in Matlacha, FL

    Ready-to-build commercial lot with residential potential and waterfront access.

    4225-4227 Pine Island Rd NW, Matlacha, FL 33993
    View details

    Lee County, FL Live-Work Space Investment Opportunities Market Analysis

    Explore 2 live-work space for sale in Lee County, FL on our real estate platform. These investment opportunities span a total of 97,566 square feet of properties for sale, with an estimated market value of $8,240,000.

    Prices for live-work properties in Lee County, FL start at $1,150,000, averaging $2,746,666, and reaching up to $3,795,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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    Browse Live-work space for Sale Near Lee, FL

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