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    San Luis Obispo, CA Commercial Real Estate for Sale

    77 results
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    San Luis Obispo Commercial Condo
    $390,000
    2,296 SF

    San Luis Obispo Commercial Condo

    2475 Victoria Ave, San Luis Obispo, CA 93401

    Commercial condo with outdoor patio, ideal for restaurant/café.

    • Large outdoor patio space (1,000 SF) in addition to 1,275 SF interior space.
    • Suitable for restaurant/cafe use due to grease trap and venting systems.
    • Located in Victoria Crossing, a community with 33 existing residential flats.
    • Onsite parking with 11 spaces, in addition to street parking.
    • New construction (built in 2023).
    Updated: Nov 24, 2025
    View details
    6.55 Acres in San Luis Obispo
    Pending
    $1,045,000
    285,318.00 Acres

    6.55 Acres in San Luis Obispo

    Calle Crotalo, San Luis Obispo, CA 93401

    Premium land with water access near downtown San Luis Obispo.

    • 6.55 acres of premium land in a desirable location.
    • Includes a "will serve" letter from Afuero Water Company with two water meter allotments.
    • Opportunity to split the property for a second APN.
    • Minutes from downtown San Luis Obispo (SLO) with easy access to amenities.
    • Surrounded by rolling hills and picturesque views.
    Updated: Feb 18
    View details
    Downtown San Luis Obispo Investment
    $1,150,000
    5,000 SF

    Downtown San Luis Obispo Investment

    Commercial property in downtown San Luis Obispo with investment potential.

    283 Higuera St, San Luis Obispo, CA 93401
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    Winery Production Facility in Edna Valley
    $15,000,000
    43,218 SF

    Winery Production Facility in Edna Valley

    Turnkey winery with high-capacity production and expansion potential.

    4915 Orcutt Rd, San Luis Obispo, CA 93401
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    Agricultural Property with Cannabis Entitlement
    $1,200,000
    123.67 Acres

    Agricultural Property with Cannabis Entitlement

    123.67-acre agricultural property with approved cannabis cultivation permit.

    2675 Cuyama Hwy, San Luis Obispo, CA 93254
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    Spanish-Style Office Building For Sale
    $1,150,000
    1,900 SF

    Spanish-Style Office Building For Sale

    Office building with apartment and courtyard in downtown San Luis Obispo.

    1124 Nipomo St, San Luis Obispo, CA 93401
    View details
    San Luis Obispo Commercial Land
    $3,900,000
    156,380.00 Acres

    San Luis Obispo Commercial Land

    3.59 acres in a planned community, retail potential.

    2040 Prado Rd, San Luis Obispo, CA 93401
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    285-Acre Vineyard and Citrus Ranch
    $6,900,000
    12,153,240.00 Acres

    285-Acre Vineyard and Citrus Ranch

    Premier San Luis Obispo ranch with vineyard, citrus, and rangeland.

    5502 Los Ranchos Rd, San Luis Obispo, CA 93401
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    Profitable Laundromat Business Opportunity
    $799,000

    Profitable Laundromat Business Opportunity

    Established laundromat business with growth potential in prime location.

    2020 Parker St, San Luis Obispo, CA 93401
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    Iconic Restaurant Building in SLO
    $895,000
    2,078 SF

    Iconic Restaurant Building in SLO

    Two-story restaurant property in the heart of downtown San Luis Obispo.

    815 Palm St, San Luis Obispo, CA 93401
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    Historic Ranch Estate Near San Luis Obispo
    $3,450,000
    2,400 SF

    Historic Ranch Estate Near San Luis Obispo

    189-acre ranch with residences, barns, and equestrian facilities.

    1498 O'sconnor Way, San Luis Obispo, CA 93405
    View details
    Modern Office Space Near Airport
    $1,821,150
    4,012 SF

    Modern Office Space Near Airport

    Professional office space near the airport, suitable for medical/office use.

    805 Aerovista Pl, San Luis Obispo, CA 93401
    View details
    Commercial Building with Office Suites
    $4,600,000

    Commercial Building with Office Suites

    Commercial building featuring office suites and warehouse storage space.

    615 Clarion Ct, San Luis Obispo, CA 93401
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    San Luis Obispo Manufacturing Lots
    $315,035

    San Luis Obispo Manufacturing Lots

    Manufacturing lots for sale in San Luis Obispo, California.

    4120 Earthwood Ln, San Luis Obispo, CA
    View details
    San Luis Obispo Manufacturing Lots
    $315,140

    San Luis Obispo Manufacturing Lots

    Manufacturing lots for sale in San Luis Obispo, California.

    4140 Earthwood Ln, San Luis Obispo, CA
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    San Luis Obispo Manufacturing Lots
    $315,385

    San Luis Obispo Manufacturing Lots

    Manufacturing lots for sale in San Luis Obispo, California.

    4145 Earthwood Ln, San Luis Obispo, CA
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    San Luis Obispo Manufacturing Lots
    $315,385

    San Luis Obispo Manufacturing Lots

    Manufacturing lots for sale in San Luis Obispo, California.

    4135 Earthwood Ln, San Luis Obispo, CA
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    San Luis Obispo Leased Investment
    $13,000,000
    34,427 SF

    San Luis Obispo Leased Investment

    34,427 SF commercial property in active commercial corridor.

    855 Aerovista Pl, San Luis Obispo, CA 93401
    View details
    Santa Rosa Professional Building For Sale
    $2,175,000

    Santa Rosa Professional Building For Sale

    Two-unit medical/general office building constructed in 1962.

    1338 Santa Rosa St, San Luis Obispo, CA 93401
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    Medical Office Space Available
    $2,830,000

    Medical Office Space Available

    Prime medical office space with high visibility in San Luis Obispo.

    689 Tank Farm Rd, San Luis Obispo, CA 93401
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    Income-Producing Retail Center For Sale
    $6,995,000

    Income-Producing Retail Center For Sale

    Fully occupied retail center on a busy commercial corridor.

    12300 Los Osos Valley Rd, San Luis Obispo, CA 93405
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    San Luis Obispo Land Parcel
    $838,530

    San Luis Obispo Land Parcel

    Land parcel ready for improvements near Highway 101.

    40154045 Earthwood Ln, San Luis Obispo, CA 93401
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    San Luis Obispo Historic Corner
    $1,300,000

    San Luis Obispo Historic Corner

    Rare opportunity to own a piece of local history.

    2143 Broad St, San Luis Obispo, CA 93401
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    San Luis Obispo Manufacturing Parcel
    $6,900,000

    San Luis Obispo Manufacturing Parcel

    Large manufacturing-zoned parcel with development options and freeway access.

    197 Suburban Rd, San Luis Obispo, CA 93401
    View details

    San Luis Obispo, CA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 52 commercial real estate for sale in San Luis Obispo, CA, showcased through 77 active listings on our real estate platform. These investment opportunities span a total of 19,254,043,156 square feet of properties for sale, with an estimated market value of $19,594,000.

    Sale prices for business properties in San Luis Obispo, CA start at $1,045,000, averaging $3,918,800, and reaching up to $9,999,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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