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    San Luis Obispo, CA Medical Office Space for Sale

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    Santa Margarita, CA Avila Beach, CA Los Osos, CA
    Corner Office Building with Private Deck
    $995,000
    1,444 SF
    Corner Office Building with Private Deck

    102 Santa Rosa 104, San Luis Obispo, CA 93405

    Two-unit office property with a private deck and uncovered parking, suited for professional or medical users.
    • Approximately 1,444‑SF corner office building configured into 2 separate units
    • Each unit has its own office space, storage, common area, and restrooms
    • Approximately 228‑SF private deck overlooking San Luis Creek
    • Cooling: central air
    • Convenient uncovered parking for tenants and visitors
    Updated: Jun 9
    View details
    Mixed-Use Commercial Property Near Courthouse
    $1,395,000
    Mixed-Use Commercial Property Near Courthouse

    1022 Mill St, San Luis Obispo, CA 93401

    Mixed-use commercial property with flexible office space and on-site parking.
    • Prime location near downtown San Luis Obispo, Highway 101, the County Courthouse, and major professional corridors.
    • Mixed‑use commercial property with a separate rear unit, offering multiple income streams or flexible workspace.
    • Flexible office configurations suitable for various professional uses.
    • On‑site parking and an outdoor patio area, enhancing tenant appeal and marketability.
    • High walk score (86) indicating convenient access to amenities.
    Updated: Apr 24
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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 2 Active listings in San Luis Obispo, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 70 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Arroyo Grande Commercial Sale Opportunity
    $699,000
    1,751 SF
    Arroyo Grande Commercial Sale Opportunity

    Versatile space suitable for medical or professional office uses.

    1577 El Camino Real, Arroyo Grande, CA 93420

    View details
    Versatile Medical/Professional Office Space
    $699,000
    Versatile Medical/Professional Office Space

    Adaptable space for medical or professional use, convenient location.

    1577 El Camino Real, Arroyo Grande, CA 93420

    View details
    Templeton Office Suite For Sale
    $185,000
    1,200 SF
    Templeton Office Suite For Sale

    Professional office suite in Templeton, near Twin Cities Hospital.

    1050 Las Tablas Rd 5, Templeton, CA 93465

    View details
    Medical Office Condo Near Hospital
    Contact for pricing
    1,272 SF
    Medical Office Condo Near Hospital

    Medical office condo with backup power system near Twin Cities Hospital.

    1105 Road Unit E Unit E, Templeton, CA 93465

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Professional Office Land Opportunity
    $999,000
    20,000 SF
    Professional Office Land Opportunity

    Approximately 4 acres of flat land in prime business zone.

    Road, Templeton, CA 93465

    View details
    Visalia Commercial Land Opportunity
    $269,500
    18,152 SF
    Visalia Commercial Land Opportunity

    Unimproved parcel for custom headquarters in Visalia's professional hub.

    4242 West Mineral King Avenue, Visalia, CA 93291

    View details
    Visalia Land Parcel Opportunity
    $239,500
    15,581 SF
    Visalia Land Parcel Opportunity

    Unimproved land parcel for custom professional headquarters in Visalia, CA.

    4232 West Mineral King Avenue, Visalia, CA 93291

    View details
    Vacant Lot Near Medical Center
    $199,900
    0.34 Acres
    Vacant Lot Near Medical Center

    Commercial land near Fresno Community Regional Medical Center and Hwy 41.

    704 N Fresno Street, Fresno, CA 93701

    View details

    Off-Market Properties in San Luis Obispo, CA

    Consider similar Off-Market properties in San Luis Obispo, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    15 Santa Rosa St
    MEDICAL BUILDING
    1,746 SF Lot: 0.38 Acres
    Value Estimation by Request

    15 Santa Rosa St, San Luis Obispo, CA 93405-1811

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    100 Casa St Ste B
    MEDICAL BUILDING
    2,625 SF Lot: 0.06 Acres
    Estimated value
    $1,415,000

    100 Casa St Ste B, San Luis Obispo, CA 93405-8803

    View details
    71 Zaca Ln
    MEDICAL BUILDING
    11,697 SF Lot: 0.78 Acres

    71 Zaca Ln, San Luis Obispo, CA 93401-7300

    View details
    21 Santa Rosa St Ste, Unit 50
    MEDICAL BUILDING
    2,148 SF Lot: 0.05 Acres
    Estimated value
    $1,005,000
    Unit 50

    21 Santa Rosa St Ste, San Luis Obispo, CA 93405-5808

    View details
    1551 Bishop St Ste, Unit 240
    MEDICAL BUILDING
    2,277 SF Lot: 0.05 Acres
    Estimated value
    $1,250,000
    Unit 240

    1551 Bishop St Ste, San Luis Obispo, CA 93401-4661

    View details
    1551 Bishop St Ste, Unit 440
    MEDICAL BUILDING
    1,132 SF Lot: 0.08 Acres
    Value Estimation by Request
    Unit 440

    1551 Bishop St Ste, San Luis Obispo, CA 93401-4663

    View details
    1545 Higuera St
    MEDICAL BUILDING
    Estimated value
    $1,200,000

    1545 Higuera St, San Luis Obispo, CA 93401-2917

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    1147 Marsh St
    MEDICAL BUILDING
    4,235 SF Lot: 0.11 Acres
    Estimated value
    $1,110,000

    1147 Marsh St, San Luis Obispo, CA 93401-3323

    View details
    San Luis Obispo, CA 93401
    MEDICAL BUILDING
    Value Estimation by Request

    San Luis Obispo, CA 93401

    View details
    1250 Peach St Ste J
    MEDICAL BUILDING
    928 SF Lot: 0.03 Acres
    Value Estimation by Request

    1250 Peach St Ste J, San Luis Obispo, CA 93401-2882

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    1250 Peach St Ste C
    MEDICAL BUILDING
    928 SF Lot: 0.02 Acres
    Value Estimation by Request

    1250 Peach St Ste C, San Luis Obispo, CA 93401-2873

    View details
    1245 Broad St
    MEDICAL BUILDING
    4,313 SF Lot: 0.16 Acres
    Estimated value
    $1,985,000

    1245 Broad St, San Luis Obispo, CA 93401-3907

    View details
    990 Boysen Ave
    MEDICAL BUILDING
    1,861 SF Lot: 0.22 Acres
    Estimated value
    $935,000

    990 Boysen Ave, San Luis Obispo, CA 93405-1313

    View details
    1941 Johnson Ave
    MEDICAL BUILDING
    36,194 SF Lot: 2.11 Acres
    Estimated value
    $1,385,000

    1941 Johnson Ave, San Luis Obispo, CA 93401-4163

    View details
    1304 Ella St Ste C
    MEDICAL BUILDING
    6,144 SF Lot: 0.42 Acres
    Estimated value
    $1,345,000

    1304 Ella St Ste C, San Luis Obispo, CA 93401-4167

    View details
    140 Casa St
    MEDICAL BUILDING
    2,219 SF Lot: 0.20 Acres
    Estimated value
    $1,270,000

    140 Casa St, San Luis Obispo, CA 93405-1804

    View details
    1551 Bishop St Ste, Unit 320
    MEDICAL BUILDING
    751 SF Lot: 0.04 Acres
    Value Estimation by Request
    Unit 320

    1551 Bishop St Ste, San Luis Obispo, CA 93401-4637

    View details
    683 California Blvd Ste, Unit 110
    MEDICAL BUILDING
    4,046 SF Lot: 0.24 Acres
    Estimated value
    $1,720,000
    Unit 110

    683 California Blvd Ste, San Luis Obispo, CA 93401-2582

    View details
    1551 Bishop St Ste, Unit 250
    MEDICAL BUILDING
    1,132 SF Lot: 0.03 Acres
    Estimated value
    $560,000
    Unit 250

    1551 Bishop St Ste, San Luis Obispo, CA 93401-4661

    View details
    891 Pismo St
    MEDICAL BUILDING
    2,048 SF Lot: 0.12 Acres
    Estimated value
    $680,000

    891 Pismo St, San Luis Obispo, CA 93401-4017

    View details
    1551 Bishop St Ste, Unit 410
    MEDICAL BUILDING
    1,978 SF Lot: 0.05 Acres
    Estimated value
    $875,000
    Unit 410

    1551 Bishop St Ste, San Luis Obispo, CA 93401-4663

    View details
    1551 Bishop St Ste, Unit 430
    MEDICAL BUILDING
    1,070 SF Lot: 0.02 Acres
    Estimated value
    $520,000
    Unit 430

    1551 Bishop St Ste, San Luis Obispo, CA 93401-4663

    View details

    San Luis Obispo, CA Medical Office Space Investment Opportunities Market Analysis

    Explore 72 medical office space for sale in San Luis Obispo, CA on our real estate platform. These investment opportunities span a total of 1,444 square feet of properties for sale, with an estimated market value of $995,000.

    Sale prices for medical spaces in San Luis Obispo, CA start at $995,000, averaging $995,000, and reaching up to $995,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 102
    Medical Office Space 19
    Office buildings 6
    Creative space 2

    Demographics Overview

    Population 79K
    Population Growth (5Y) -12.3%
    Median Household Income $82,388
    College Educated 27.6%

    High-Yield Neighborhoods for Investment

    Identify San Luis Obispo submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    93401 $1.4M

    Taxes & Financing

    Tax Rate (average for all types) 1.14%
    Property Tax per SF $13.51 per SF
    Tax Rate vs County Average 0.01 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in San Luis Obispo County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in San Luis Obispo County

    Retail

    Property Size Breakdown

    The majority of commercial real estate listings in San Luis Obispo fall within the 10,000 to 25,000 square foot range.

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