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San Luis Obispo, CA Medical Office Space for Sale

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Two-Unit Medical Office Building
Updated: Apr 21, 2025
Two-Unit Medical Office Building

1338 Santa Rosa Street, San Luis Obispo, CA 93401

$1,950,000
3,861 sqft
Two independent medical office suites in the Santa Rosa Professional Building at 1338‑1340 Santa Rosa Street
Built in 1962 and currently operated as a 2‑unit dental office since construction
Each suite offers approximately 1,930 SF with mirror‑image floorplans
Property features a corner lot and level, rectangular topography
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This listing looks promising.

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1338 Santa Rosa Street, San Luis Obispo, CA 93401

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Turnkey Medical Office Building
Updated: Mar 28
Turnkey Medical Office Building

699 California Blvd, San Luis Obispo, CA 93401

$2,150,000
3,000 sqft
Single‑level 3,000 SF medical office building built in 2005 and rebuilt in 2005
Two separate 1,500 SF suites with floorplans suited for healthcare providers or other professionals
Each suite includes two private ADA‑compliant restrooms, waiting room, and reception area
Multiple exam rooms plus functional back offices and storage areas in each suite
15 on‑site parking spaces for patients and staff
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Medical Condo with Onsite Parking
Medical Condo with Onsite Parking

1250 Peach St H, San Luis Obispo, CA 93401

$525,000
0.03 AC lot

Well-appointed medical condo near Highway 101 with onsite parking.

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Medical Office with Conference Rooms
Medical Office with Conference Rooms

805 Aerovista Pl, San Luis Obispo, CA 93401

Contact for pricing
4,012 sqft

Modern office suite includes seven private offices, an executive conference room, and a full break room.

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Four-Suite Professional Medical Office
Four-Suite Professional Medical Office

894 Meinecke, San Luis Obispo, CA 93405

$1,650,000

Well maintained four-suite office building with long-term tenancies, located one block from Sierra Vista Hospital.

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Medical Office and Executive Suite
Medical Office and Executive Suite

805 Aerovista Pl, San Luis Obispo, CA 93401

Contact for pricing
4,054 sqft

Modern office buildout includes private offices, a conference room, open bullpens, and a break room.

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Medical Office Corner Suite
Medical Office Corner Suite

689 Tank Farm Rd, San Luis Obispo, CA 93401

Contact for pricing
7,727 sqft

Medical office suite with open layout, conference room, kitchenette, and elevator access within a corner location.

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Freestanding Medical Office Building
Freestanding Medical Office Building

3565 S Higuera, San Luis Obispo, CA 93401

Contact for pricing
2,800 sqft

Freestanding former chiropractic office features an efficient layout, generous reception, and 10 on-site parking spaces.

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Medical Office Suite with Exam Rooms
Medical Office Suite with Exam Rooms

1551 Bishop Unit B210, San Luis Obispo, CA 93401

Contact for pricing
1,659 sqft

A 1,659 SF medical office suite with ample parking, including five exam rooms and a reception area.

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Medical Office Suite with Parking
Medical Office Suite with Parking

620 California Unit G, San Luis Obispo, CA 93401

Contact for pricing
3,098 sqft

Medical suite currently configured for pediatric dentistry with on-site parking near Highway 101.

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Leased Medical Surgery Center Suites
Leased Medical Surgery Center Suites

1304 Ella St CD, San Luis Obispo, CA 93401

$3,515,000

Fully leased surgery center plus an administrative office interest, both occupied through 2030.

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Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 11 Active listings in San Luis Obispo, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 61 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Converted Residential Office Building
Converted Residential Office Building

117 E Fesler Street, Santa Maria, CA 93454

$595,000
1,402 sqft 0.17 AC lot

Converted home with multiple private offices, reception area, and onsite parking in Santa Maria.

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End Unit Medical Office Condo
End Unit Medical Office Condo

4555 El Camino Real Unit A, Atascadero, CA 93422

$493,500
2,053 sqft

End unit medical office condo with reception, three offices, two bathrooms, and ample parking within San Anselmo Center.

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Medical Office with Exam Rooms
Medical Office with Exam Rooms

821 E Chapel St, Santa Maria, CA 93454

Contact for pricing
1,306 sqft

Well-appointed medical office suite with exam rooms, waiting and reception areas, and ample parking.

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Medical/Professional Office Building For Sale
Medical/Professional Office Building For Sale

8655 Morro Rd, Atascadero, CA 93422

$1,790,000
0.42 AC lot

Medical/Professional office building with five suites, excellent visibility.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Visalia Commercial Land Opportunity
Visalia Commercial Land Opportunity

4242 West Mineral King Avenue, Visalia, CA 93291

$269,500
18,152 sqft 0.42 AC lot

Unimproved parcel for custom headquarters in Visalia's professional hub.

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Visalia Land Parcel Opportunity
Visalia Land Parcel Opportunity

4232 West Mineral King Avenue, Visalia, CA 93291

$239,500
15,581 sqft 0.36 AC lot

Unimproved land parcel for custom professional headquarters in Visalia, CA.

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Vacant Commercial Development Lot
Vacant Commercial Development Lot

704 N Fresno Street, Fresno, CA 93701

$199,900
0.34 AC lot

Vacant commercial lot near Fresno Community Regional Medical Center and Hwy 41/Tulare Ave exit.

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Ridgecrest Commercial Parcel For Sale
Ridgecrest Commercial Parcel For Sale

067-024-01 N Norma St, Ridgecrest, CA 93555

$89,500
0.39 AC lot

Prime commercial land in a high-growth business hub.

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Off-Market Properties in San Luis Obispo, CA

Consider similar Off-Market properties in San Luis Obispo, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

15 Santa Rosa St
MEDICAL BUILDING

15 Santa Rosa St, San Luis Obispo, CA 93405-1811

Value Estimation by Request
1,746 sqft 0.38 AC lot
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100 Casa St Ste B
MEDICAL BUILDING

100 Casa St Ste B, San Luis Obispo, CA 93405-8803

$1,415,000
Estimated value
2,625 sqft 0.06 AC lot
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71 Zaca Ln
MEDICAL BUILDING

71 Zaca Ln, San Luis Obispo, CA 93401-7300

$2,145,000
Estimated value
11,697 sqft 0.78 AC lot
View details
21 Santa Rosa St Ste, Unit 50
MEDICAL BUILDING

21 Santa Rosa St Ste, San Luis Obispo, CA 93405-5808

Unit 50
$1,005,000
Estimated value
2,148 sqft 0.05 AC lot
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1551 Bishop St Ste, Unit 240
MEDICAL BUILDING

1551 Bishop St Ste, San Luis Obispo, CA 93401-4661

Unit 240
$1,250,000
Estimated value
2,277 sqft 0.05 AC lot
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1551 Bishop St Ste, Unit 440
MEDICAL BUILDING

1551 Bishop St Ste, San Luis Obispo, CA 93401-4663

Unit 440
Value Estimation by Request
1,132 sqft 0.08 AC lot
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1147 Marsh St
MEDICAL BUILDING

1147 Marsh St, San Luis Obispo, CA 93401-3323

$1,110,000
Estimated value
4,235 sqft 0.11 AC lot
View details
1250 Peach St Ste J
MEDICAL BUILDING

1250 Peach St Ste J, San Luis Obispo, CA 93401-2882

Value Estimation by Request
928 sqft 0.03 AC lot
View details
1250 Peach St Ste C
MEDICAL BUILDING

1250 Peach St Ste C, San Luis Obispo, CA 93401-2873

Value Estimation by Request
928 sqft 0.02 AC lot
View details
1245 Broad St
MEDICAL BUILDING

1245 Broad St, San Luis Obispo, CA 93401-3907

$1,985,000
Estimated value
4,313 sqft 0.16 AC lot
View details
990 Boysen Ave
MEDICAL BUILDING

990 Boysen Ave, San Luis Obispo, CA 93405-1313

$935,000
Estimated value
1,861 sqft 0.22 AC lot
View details
1941 Johnson Ave
MEDICAL BUILDING

1941 Johnson Ave, San Luis Obispo, CA 93401-4163

$1,385,000
Estimated value
36,194 sqft 2.11 AC lot
View details
1304 Ella St Ste C
MEDICAL BUILDING

1304 Ella St Ste C, San Luis Obispo, CA 93401-4167

$1,345,000
Estimated value
6,144 sqft 0.42 AC lot
View details

San Luis Obispo, CA Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in San Luis Obispo, CA, showcased through 11 active listings on our real estate platform. These investment opportunities span a total of 30,211 square feet of properties for sale, with an estimated market value of $9,790,000.

Sale prices for medical spaces in San Luis Obispo, CA start at $525,000, averaging $1,958,000, and reaching up to $3,515,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 120
Medical Office Space 26
Office buildings 10
Creative space 4

Demographics Overview

Population 79K
Population Growth (5Y) -12.3%
Median Household Income $82,388
College Educated 27.6%

High-Yield Neighborhoods for Investment

Identify San Luis Obispo submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
93405 $995K
93401 $1.7M

Taxes & Financing

Tax Rate (average for all types) 1.14%
Property Tax per SF $13.51 per SF
Tax Rate vs County Average 0.01 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in San Luis Obispo County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in San Luis Obispo fall within the 10,000 to 25,000 square foot range.

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