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    San Diego, CA Mixed-use Properties for Sale

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    Three-Story Mixed-Use Building
    Updated: Mar 11
    Three-Story Mixed-Use Building

    2368 2nd AVE, San Diego, CA 92101

    $2,669,000
    3,800 sqft 0.13 AC lot
    3,800‑square‑foot, three‑story mixed‑use building
    0.1251‑acre parcel in San Diego, CA 92101
    Mixed‑use zoning supports commercial and residential configurations
    Independent floor access with private ingress and egress
    Onsite parking included
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    Mixed-Use Property With Five Units
    Updated: Jun 2
    Mixed-Use Property With Five Units

    110 Maple, San Diego, CA 92103

    $4,890,000
    3,750 sqft 0.13 AC lot
    Five‑unit configuration with one professional office and four residential units
    3,750 square feet on a 0.1285‑acre corner parcel
    Two residential units rebuilt in 2024
    New electrical, plumbing, insulation, HVAC, meters, and fire sprinkler system
    Dual street frontage at 1st Ave and Maple St
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    Corner-Lot Mixed-Use Property
    Corner-Lot Mixed-Use Property

    3275 Euclid, San Diego, CA 92105

    $900,000
    0.11 AC lot

    Versatile storefront property with separate business and private-access entrances in a transit-oriented commercial setting.

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    Mixed-Use Property with Residence
    Mixed-Use Property with Residence

    4741 Point Loma Avenue, San Diego, CA 92107

    $2,295,000
    3,376 sqft

    Three-part configuration combines commercial suites with a two-level upper residence.

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    Remodeled Mixed-Use Property
    Remodeled Mixed-Use Property

    825-829 Washington St., San Diego, CA 92103

    $1,189,000
    1,778 sqft 0.03 AC lot

    Three-unit office and retail property with updated building systems and finishes.

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    Three-Story Mixed-Use Building
    Three-Story Mixed-Use Building

    2368 2nd Ave, San Diego, CA 92101

    $2,669,000
    3,800 sqft

    Three-story mixed-use building features independently accessible floors with private in- and egress and onsite parking.

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    Updated Mixed-Use Office-Retail Building
    Updated Mixed-Use Office-Retail Building

    3675 Voltaire St, San Diego, CA 92106

    $4,500,000
    11,060 sqft

    Retail space at grade is paired with offices above in a flexible commercial layout.

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    Mixed-Use Property with Auto Uses
    Mixed-Use Property with Auto Uses

    1235 Cushman Ave, San Diego, CA 92110

    $5,950,000
    12,650 sqft

    Automotive operations and a one-bedroom apartment occupy the property, with month-to-month tenancy in place.

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    Mixed-Use Restaurant and Office Property
    Mixed-Use Restaurant and Office Property

    4475 Mission Bouleard, San Diego, CA 92109

    $31,000,000
    38,103 sqft 1.43 AC lot

    Combines ground-floor retail and restaurants with executive office suites above.

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    Mixed-Use Property in Opportunity Zone
    Mixed-Use Property in Opportunity Zone

    4170 Fairmount Ave, San Diego, CA 92105

    $999,000
    1,404 sqft

    Mixed-use property with high foot traffic in City Heights.

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    Mixed-Use Property with Retail Units
    Mixed-Use Property with Retail Units

    3651 55 Ocean View Boulevard, San Diego, CA 92113

    $700,000
    3,450 sqft 0.15 AC lot

    A five-unit mixed-use building with three retail spaces and two 1-bedroom units, built in 1926.

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    Bankers Hill Mixed-Use Opportunity
    Bankers Hill Mixed-Use Opportunity

    2368 2nd AVE, San Diego, CA 92101

    $2,849,000
    3,800 sqft

    Three-story mixed-use property in Bankers Hill near Balboa Park.

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    Mixed-Use Property in Opportunity Zone
    Mixed-Use Property in Opportunity Zone

    3651 55 Ocean View Boulevard, San Diego, CA 92113

    $795,000
    3,450 sqft 0.16 AC lot

    Five-unit mixed-use property with redevelopment potential in San Diego.

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    Mixed-Use Property with Alley Access
    Mixed-Use Property with Alley Access

    1434-44 Garnet Ave, San Diego, CA 92109

    $1,995,000
    1,622 sqft 0.14 AC lot

    Retail/office space includes a detached studio and rear open area.

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    Corner-Lot Mixed-Use Building
    Corner-Lot Mixed-Use Building

    2754 Imperial Avenue, San Diego, CA 92102

    Contact for pricing
    4,272 sqft 0.13 AC lot

    Private offices, four restrooms, a kitchenette, and on-site parking accommodate flexible commercial occupancy.

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    Signalized Corner Mixed-Use Property
    Signalized Corner Mixed-Use Property

    1075 ROSECRANS ST SAN DIEGO CA 92106-3044, San Diego, CA 92106

    Contact for pricing
    4,209 sqft 0.22 AC lot

    CC 4-2 zoning supports retail, office, residential, and hospitality applications.

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    Single-Tenant Mixed-Use Building
    Single-Tenant Mixed-Use Building

    2317 Hotel Circle South, San Diego, CA 92108

    Contact for pricing
    9,240 sqft 1.86 AC lot

    Two-story retail and office asset with CO-2-2 zoning and on-site parking.

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    Freestanding Mixed-Use Lab Building
    Freestanding Mixed-Use Lab Building

    9955 Mesa Rim Rd, San Diego, CA 92121

    Contact for pricing
    15,853 sqft 5.45 AC lot

    Renovation plans include facade and landscaping upgrades, with warehouse and laboratory infrastructure already in place.

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    Mixed-Use Building with Residential Units
    Mixed-Use Building with Residential Units

    4702-4714 University Ave, San Diego, CA 92105

    Contact for pricing
    11,517 sqft 0.45 AC lot

    Mixed-use improvements include four vacant one-bedroom, one-bath residential units.

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    Mixed-Use Investment in La Playa
    Mixed-Use Investment in La Playa

    1051-65 Rosecrans Street, San Diego, CA 92106

    Contact for pricing
    7,600 sqft

    Mixed-use property in Point Loma with retail and residential units.

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    Mixed-Use Automotive Property
    Mixed-Use Automotive Property

    1235 Cushman Ave # 1235, San Diego, CA 92110

    Contact for pricing
    12,650 sqft

    Commercial property combines established automotive uses with a one-bedroom apartment and month-to-month tenancy.

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    Three-Building Mixed-Use Property
    Three-Building Mixed-Use Property

    2329 India Street, San Diego, CA 92101

    Contact for pricing
    4,274 sqft

    Mixed-use offering with three separate buildings and on-site parking stalls for operational flexibility.

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    Mixed-Use Building with Vacant Office
    Mixed-Use Building with Vacant Office

    901 Fourth Ave, San Diego, CA 92101

    Contact for pricing
    14,000 sqft 0.34 AC lot

    Corner property combines retail, office, and entertainment uses with adaptive-reuse plans for the upper level.

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    Remodeled Hillcrest Office & Retail
    Remodeled Hillcrest Office & Retail

    825 Washington St., San Diego, CA 92103

    $1,189,000
    0.03 AC lot

    Remodeled office and retail space in dynamic Hillcrest neighborhood.

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    San Diego, CA Mixed-Use Properties Market Trends and Statistics

    Explore 72 mixed-use properties for sale in San Diego, CA, showcased through 69 active listings on our real estate platform. These investment opportunities span a total of 433,864 square feet of properties for sale, with an estimated market value of $93,711,900.

    Sale prices for multi use buildings in San Diego, CA start at $624,000, averaging $3,748,476, and reaching up to $31,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Live-work space 14

    Demographics Overview

    Population 1.38M
    Population Growth (5Y) -2.1%
    Median Household Income $109,172
    College Educated 31.4%

    High-Yield Neighborhoods for Investment

    Identify San Diego submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    92113 $1.1M
    92105 $1.8M
    92114 $1.9M
    92101 $2.4M
    92103 $4.2M

    Taxes & Financing

    Tax Rate (average for all types) 1.17%
    Property Tax per SF $13.93 per SF
    Tax Rate vs County Average 0.03 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in San Diego County

    New Delisted

    Total CRE Inventory on Market (SF)

    Property Size Breakdown

    The majority of commercial real estate listings in San Diego fall within the 100,000+ square foot range.

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    Browse Mixed-use properties for Sale Near San Diego, CA

    Popular Searches in San Diego, CA

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    Most Searched ZIP Codes in San Diego, CA

    • 92101
    • 92103
    • 92113
    • 92104
    • 92106
    • 92110
    • 92105
    • 92109
    • 92102
    • 92107
    • 92037
    • 92121

    Featured San Diego Real Estate Agencies

    Realmo connects you with licensed San Diego CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Century 21 Horizon
    4134 Adams Ave., #101 San Diego, CA 92116
    Phone: 16192805888
    www.century21horizon.com
    Hacienda Realty
    4683 Pt. Loma Ave. San Diego, CA 92107
    Phone: 16194174493
    www.haciendasd.com

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