Lee County, FL Hospitality properties for sale

Updated: Jun 24

Mixed-Use Development Site

1025 2nd Street, Fort Myers Beach, FL 33931

$800,000

0.12 AC lot

Commercial lot in downtown Fort Myers Beach near Harbour House at the Inn (adjacent to Times Square).
Downtown commercial zoning allows a range of uses including residential, lodging, office, restaurant, and retail.
Concept provided: commercial ground level with 6 one‑bedroom condo/hotel rooms on the 2nd and 3rd floors.
Year built listed as 1972.

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Updated: May 8

Waterfront Lot with Flexible Zoning

1339 Santos Road, Fort Myers Beach, FL 33931

$1,250,000

0.14 AC lot

5,997+/- sq. ft. waterfront lot with seawall and canal access
Santos Zoning District with allowable uses including office with residential apartment above, duplex, and bed & breakfast
Other allowable uses listed include single‑family residence and a water taxi operation (request the Zoning Verification Letter for complete details)
Located directly across from Lani Kai Island Resort and steps from the beach
In the weekly rental district, supporting short‑term rental use (per listed zoning details)

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Luxury Motorcoach Resort Property

13197 Golden Palms Circle, Fort Myers, FL 33913

$525,000

840 sqft 0.14 AC lot

High-end casita in Golden Palms Luxury Motorcoach Resort.

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Waterfront Resort Property in Matlacha

12200/12210 Shoreview DR, Matlacha, FL 33993

$3,250,000

7,400 sqft 1.00 AC lot

Renovated waterfront resort with rental potential in Matlacha, Florida.

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Waterfront RV Lot with Cabana

13875 Golden Palms Cir lot: 27, Fort Myers, FL 33913

$449,000

840 sqft 0.14 AC lot

Luxury RV lot with custom cabana in gated resort.

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Fort Myers Beach Commercial Lot

1041 3rd Street, Fort Myers Beach, FL 33931

$2,300,000

0.07 AC lot

Double lot in entertainment district, near beach and Margaritaville Resort.

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Lakefront RV Resort Lot with Cabana

13317 Golden Palms Circle, Fort Myers, FL 33913

$499,000

0.14 AC lot

East-facing lakefront lot in a luxury motorcoach resort with a finished coach cabana and resort amenities.

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Sanibel Island Motel Opportunity

706 Donax St, Sanibel, FL 33957

$5,300,000

0.50 AC lot

Two Sanibel Island motels with strong rental income.

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Private Tropical Retreat RV Lot

5750 Burrwood Court, Fort Myers, FL 33905

$132,900

0.20 AC lot

Private RV lot with mature landscaping and comfortable casita.

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Land with Shed in Fort Myers

5465 Cypress Trail Resort Circle, Fort Myers, FL 33905

$200,000

0.08 AC lot

Concrete RV lot with shed and landscaping in Fort Myers.

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I-75 Hotel Building Site

4290 Boatways Rd, Fort Myers, FL 33905

$2,500,000

2.35 AC lot

Hotel building site on I-75, near Cracker Barrel.

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Concrete Lot with Tiki Hut

5151 Cypress Trail Resort Circle, Fort Myers, FL 33905

$200,000

0.07 AC lot

Concrete lot featuring a tiki hut and finished shed.

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Luxury Motor Coach Resort Lot

13149 GOLDEN PALMS Circle, Fort Myers, FL 33913

$525,000

0.14 AC lot

Waterfront lot with casita in Golden Palms Resort.

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Turnkey Motel and Cottages

14621 McGregor Boulevard, Fort Myers, FL 33908

Contact for pricing

7,017 sqft

Turnkey sale featuring 18 units across seven buildings, including cottages and motel rooms.

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Paved RV Lot with Gazebo

10329 Fire Flag Trail, Fort Myers, FL 33905

$200,000

0.07 AC lot

South-facing, completely paved RV lot with a 10x12 gazebo and 10x12 storage shed.

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Fort Myers Lot with Tiki

10212 Yellowtop Trail, Fort Myers, FL 33905

$197,900

0.08 AC lot

Northwest-facing lot with tiki, shed, and landscaping.

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Hospitality Resort Property

1167 Estero Boulevard, Fort Myers Beach, FL 33931

$6,500,000

For sale hospitality property on Estero Boulevard, positioned directly across from a Margaritaville pool.

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Lakefront RV Lot

13815 Golden Palms Circle, Fort Myers, FL 33913

$145,000

0.14 AC lot

Deeded lakefront RV lot within Golden Palms Luxury Motorcoach Resort, offering resort amenities and an on-lot paver pad.

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Updated Boutique Hospitality Property

4330 Bonita Beach Rd, Bonita Springs, FL 34134

$3,495,000

Boutique inn near Bonita Beach with upside potential.

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Mixed-Use Development Lot

1025 2nd Street, Fort Myers Beach, FL 33931

$800,000

Commercial lot in downtown zoning allows for mixed uses including lodging, office, restaurant, retail, and residential.

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Sanibel Island Motel Portfolio

706 Donax Street, Sanibel, FL 33957

$5,300,000

Two nightly-rental motel/hotel properties renovated in 2024 are offered together for ownership.

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Hotel and Duplex Redevelopment Portfolio

4819 Tradewinds Drive, Sanibel, FL 33957

$3,000,000

Cleared Gulf-front hotel and duplex sites positioned for nightly-rental redevelopment on Sanibel Island.

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Beachfront Hotel on Fort Myers

6530 Estero Boulevard, Fort Myers Beach, FL 33931

$15,900,000

1,282 sqft 1.32 AC lot

Direct beachfront 34-room hotel on 1.32 acres.

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Renovated Midscale Hotel Opportunity

4760 S Cleveland Ave, Fort Myers, FL 33907

$10,000,000

Turnkey midscale hotel with 135 operational guest rooms and updated amenities, including an outdoor pool and free breakfast.

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Lee County, FL Hospitality Properties Market Trends and Statistics

Explore 72 hospitality properties for sale in Lee County, FL, showcased through 27 active listings on our real estate platform. These investment opportunities span a total of 10,362 square feet of properties for sale, with an estimated market value of $20,124,000.

Sale prices for hospitality properties in Lee County, FL start at $449,000, averaging $5,031,000, and reaching up to $15,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.