Drug Store

South Carolina Drug Stores for Lease

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Retail Property with Walgreens Lease
Updated: Nov 24, 2025
Retail Property with Walgreens Lease

1537 Charleston Hwy, West Columbia, SC

Contact for pricing
14,820 sqft
Lease is corporately guaranteed by Walgreens Boots Alliance.
Walgreens is the second largest pharmacy retail chain in the United States.
Walgreens operates 9,000+ locations.
Walgreens has annual revenue exceeding $139 billion.
Walgreens is one of the ten largest retailers in the country.
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Retail Space with Drive-Thru
Updated: Nov 5, 2025
Retail Space with Drive-Thru

1535 John C Calhoun, Orangeburg, SC

Contact for pricing
10,725 sqft
Outparcel to a WalMart Neighborhood Market
Former CVS with drive thru, offering ~10,725 SF
Located on the hard corner of John C. Calhoun Drive at Stonewall Jackson Street
Prominent Pylon Sign with Digital Reader Board
Access on John C. Calhoun and Stonewall Jackson
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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 2 Active listings in South Carolina, we suggest exploring alternatives. Similar 13 Properties for Sales.

Similar Spaces for Sale in South Carolina

Consider Similar Space for Sale. We found 13 Spaces matching your search parameters.

Single-Tenant CVS Retail Building
Single-Tenant CVS Retail Building

105 Foothills Center Dr, West Union, SC 29696

$1,630,000
10,000 sqft

A leased pharmacy asset on a long-running NNN structure with a corporate guaranty from CVS Health.

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Two-Unit Medical Office Building
Two-Unit Medical Office Building

110 E Main St, Kingstree, SC 29556

$715,000
7,076 sqft 0.29 AC lot

Two-unit, brick commercial building with 100% occupancy, zoned CC, and included supplemental parking.

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CVS Investment Opportunity in Cayce
CVS Investment Opportunity in Cayce

500 Knox Abbott Drive, Cayce, SC 29033

$5,780,000
11,982 sqft

CVS property near University of South Carolina with stable income.

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Three-Story Mixed-Use Investment Property
Three-Story Mixed-Use Investment Property

651 King Street, Charleston, SC 29403

$4,695,000
4,253 sqft 0.05 AC lot

Newly constructed 2024 mixed-use building with a ground-floor NNN-leased tenant and upper-floor short-term rental units.

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Corporate-Backed NNN Retail Investment
Corporate-Backed NNN Retail Investment

204 HAMPTON AVE, Pickens, SC 29671

$2,421,000

For-sale NNN retail asset offered with a corporate-backed lease structure per broker remarks.

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Tenant-Occupied Pharmacy Retail Building
Tenant-Occupied Pharmacy Retail Building

206 E Main Street, Walhalla, SC 29691

$350,000

2,000 sq ft downtown retail building leased to Walhalla Pharmacy with a recently installed HVAC system.

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New Retail Property For Sale
New Retail Property For Sale

913 E Main Street, Laurens, SC 29360

$2,947,000

New construction retail property with a 15-year lease.

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Corner Retail Storefront Building
Corner Retail Storefront Building

212 Pearl Street, Darlington, SC 29532

Contact for pricing
2,454 sqft

Established storefront building with corner access from two streets and ample paved parking, previously used as a pharmacy.

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Pharmacy Retail Building
Pharmacy Retail Building

121 North Main Street, Woodruff, SC 29388

Contact for pricing

Built in 2002 and currently under a Walgreens purchase with a Walgreens guarantee.

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Retail Storefront Property
Retail Storefront Property

734 N Greenwood, Ware Shoals, SC 29692

Contact for pricing

Retail storefront property available for sale at 734 N Greenwood in Ware Shoals, SC.

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Pharmacy Retail Building with Drive Access
Pharmacy Retail Building with Drive Access

1401 Chapin Rd, Chapin, SC 29036

Contact for pricing

Former Rite Aid property currently tied to a long-term Walgreens lease with three ingress/egress points.

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NNN Drive-Thru Pharmacy & Fuel
NNN Drive-Thru Pharmacy & Fuel

680 Old Greenville Highway, Clemson, SC 29631

Contact for pricing

NNN leased property with a drive-thru pharmacy and detached six-pump fueling station under a Walmart-guaranteed lease.

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Freestanding NNN Walgreens Investment Opportunity
Freestanding NNN Walgreens Investment Opportunity

1101 Hwy 9 Bypass W, Lancaster, SC 29720

$4,235,000
14,820 sqft

NNN Walgreens in fast-growing Charlotte MSA with long-term lease.

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South Carolina Drug stores Market Trends and Statistics

Explore Drug stores leasing options in South Carolina with 2 listings featured on our commercial real estate exchange. The current inventory includes 25,545 square feet of properties.
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