Advertise
    Santee, SC

    Santee, SC Commercial Real Estate for Sale

    Notify Me
    List
    Map
    Vance, SC Summerton, SC Elloree, SC Holly Hill, SC Eutawville, SC Cameron, SC Bowman, SC Manning, SC
    16 properties
    Sort:
    Commercial Building with Self-Storage Units
    Updated: Jul 1, 2025
    Commercial Building with Self-Storage Units

    9158 Old Number Six Highway, Santee, SC 29142

    $1,900,000
    3,282 sqft 1.00 AC lot
    Commercial building built to accommodate two separate businesses, with a second story for offices or storage
    Rear includes 22 storage units currently rented for full‑time use
    Located about 2,500 linear feet from Hwy 195 on Highway 6 at the corner to Somerset homes and across from the entrance to Santee‑Cooper Resort
    Frame construction with vinyl flooring and a basement
    Heating: electric (heating); cooling: heat pump
    View details
    Land in Established Santee Community
    Updated: Oct 6, 2025
    Land in Established Santee Community

    Ellexlee Road, Santee, SC 29142

    $150,000
    5.00 AC lot
    Established community offering a welcoming atmosphere.
    Prime location at coordinates -80.48261, 33.45493.
    Phone available, making communication easy.
    View details
    Wooded Commercial Land
    Wooded Commercial Land

    Five Chop Road, Santee, SC 29142

    Contact for pricing
    0.47 AC lot

    Wooded commercial parcel between an Interstate 95 ramp and U.S. Route 301, with interstate exposure and constrained development potential.

    View details
    See what stands out in Orangeburg County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

    Cap Rate available after sign in
    NOI available after sign in
    Local Demand available after sign in
    Prime Commercial Land in Santee
    Prime Commercial Land in Santee

    656 Bass Drive, Santee, SC 29142

    $339,000
    4.65 AC lot

    Shovel-ready land near I-95, ideal for retail development.

    View details
    Residential Land in Gated Resort
    Residential Land in Gated Resort

    110 Cooper Drive, Santee, SC 29142

    $85,000
    0.54 AC lot

    Build in a gated lakeside golf community with established amenities and mature trees on a sizeable lot.

    View details
    Gated Lake Marion Golf Community Lot
    Gated Lake Marion Golf Community Lot

    128 Cooper Circle, Santee, SC 29142

    $85,000
    0.48 AC lot

    Build your home on a wooded homesite within a gated golf resort minutes from I-95 and Lake Marion.

    View details
    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Prime Santee Land Opportunity
    Prime Santee Land Opportunity

    Highway 301 & 15, Santee, SC 29142

    $1,255,000
    18.17 AC lot

    18-acre corner tract near I-95 in Santee, SC.

    View details
    Undeveloped Land Parcel
    Undeveloped Land Parcel

    38-200 Laval Road, Santee, SC 29142

    $80,000
    304,920 sqft 7.00 AC lot

    7-acre undeveloped land parcel is offered for sale off Laval Road.

    View details
    Prime Corner Lot in Santee
    Prime Corner Lot in Santee

    Highway 15 And 301, Santee, SC 29142

    $1,545,000
    22.04 AC lot

    Highly visible acreage near I-95, ideal for development.

    View details
    Prime Commercial Land Near I-95
    Prime Commercial Land Near I-95

    676 Bass Dr, Santee, SC

    Contact for pricing
    1.51 AC lot

    Shovel-ready land near I-95, ideal for retail development.

    View details
    Freestanding Retail Property For Sale
    Freestanding Retail Property For Sale

    100 Bass Dr, Santee, SC

    Contact for pricing
    9,993 sqft 1.69 AC lot

    Freestanding retail property with investment-grade tenant Dollar Tree.

    View details
    Three-Unit Mixed-Use Building
    Three-Unit Mixed-Use Building

    2204 Bass Drive, Santee, SC 29030

    Contact for pricing

    Renovated commercial building with adaptable interiors, paved parking, and multiple utility options.

    View details
    Waterfront Development Land
    Waterfront Development Land

    332 Bass Dr, Santee, SC 29142

    Contact for pricing

    Wooded waterfront acreage overlooks Chapel Branch and Santee State Park.

    View details
    Cleared Commercial Land
    Cleared Commercial Land

    8640 Old Number Six Hwy, Santee, SC 29142

    Contact for pricing

    General Commercial zoning with water, sewer, and power capacity already in place.

    View details
    NNN Property with Corporate Lease
    NNN Property with Corporate Lease

    101 William Clark Blvd, Santee, SC 29142

    Contact for pricing

    Fully leased retail asset with a corporate guarantee, extended renewal options, and limited landlord responsibilities.

    View details
    Commercial Land with Interstate Access
    Commercial Land with Interstate Access

    8842 Old Number Six Hwy, Santee, SC 29142

    Contact for pricing

    Commercial land offering access from both roads and a connection to the interstate.

    View details
    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 16 Active listings in Santee, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 56 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Commercial Land with Highway Frontage
    Commercial Land with Highway Frontage

    4 Old Number Six Highway, Vance, SC 29163

    $229,900
    121,097 sqft

    Partially cleared land includes two curb cuts and direct highway access for future site planning.

    View details
    Land
    Land

    00 Cooper Lane, Summerton, SC 29148

    $74,000
    52,272 sqft

    Commercial land · 52,272 SF

    View details
    Zoned Residential or Commercial Land
    Zoned Residential or Commercial Land

    Cooper Lane (fronts Hwy 301 St Paul Road) lot: #13, Summerton, SC 29148

    $74,000
    1.19 AC lot

    1.19-acre parcel with 100 feet of frontage on Hwy 301/15 near an I-95 interchange.

    View details
    Farmland Tract Off Highway
    Farmland Tract Off Highway

    3 Old Number Six Highway, Vance, SC 29163

    $79,990

    For-sale farmland tract located along Old Number Six Hwy near Westberry Dr in Orangeburg County.

    View details

    Off-Market Properties in Santee, SC

    Consider similar Off-Market properties in Santee, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    Hwy 6th 6
    WHOLESALE OUTLET, DISCOUNT STORE

    Hwy 6th 6, Santee, SC 29142

    $105,000
    Estimated value
    10,168 sqft 1.78 AC lot
    View details
    657 Bass Dr
    FINANCIAL BUILDING

    657 Bass Dr, Santee, SC 29142

    $180,000
    Estimated value
    2,761 sqft 0.88 AC lot
    View details
    8832 Old Number 6th Hwy
    MOTEL

    8832 Old Number 6th Hwy, Santee, SC 29142

    Value Estimation by Request
    4,388 sqft 1.30 AC lot
    View details
    8842 Old Number 6th Hwy
    OFFICE BUILDING

    8842 Old Number 6th Hwy, Santee, SC 29142

    Value Estimation by Request
    1,003 sqft 0.41 AC lot
    View details
    748 Bass Dr
    AUTO REPAIR, GARAGE

    748 Bass Dr, Santee, SC 29142-8941

    $140,000
    Estimated value
    2,400 sqft 0.92 AC lot
    View details
    8909 Old Number 6th Hwy
    CONVENIENCE STORE

    8909 Old Number 6th Hwy, Santee, SC 29142-8606

    $280,000
    Estimated value
    5,880 sqft 1.28 AC lot
    View details
    2202 Bass Dr
    RETAIL STORES (PERSONAL SERVICES)

    2202 Bass Dr, Santee, SC 29142

    $190,000
    Estimated value
    2,028 sqft 0.71 AC lot
    View details
    8779 Old Number 6th Hwy
    OFFICE BUILDING

    8779 Old Number 6th Hwy, Santee, SC 29142

    $650,000
    Estimated value
    1,944 sqft 0.30 AC lot
    View details

    Santee, SC Commercial Real Estate Market Trends and Statistics

    Explore 72 commercial real estate for sale in Santee, SC, showcased through 16 active listings on our real estate platform. These investment opportunities span a total of 318,195 square feet of properties for sale, with an estimated market value of $5,439,000.

    Sale prices for business properties in Santee, SC start at $80,000, averaging $679,875, and reaching up to $1,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Demographics Overview

    Population 4,658
    Population Growth (5Y) -10.2%
    Median Household Income $50,673
    College Educated 32.1%

    High-Yield Neighborhoods for Investment

    Identify Santee submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29142 $604.3K

    Listings Trend

    New vs delisted commercial listings in Orangeburg County

    New Delisted

    Need Help?

    Reach out if you need assistance with Realmo tools or have questions about your listings

    Contact Us

    Browse Commercial real estate for Sale Near Santee, SC

    Popular Searches in Santee, SC

    Popular Categories

    Most Searched ZIP Codes in Santee, SC

    • 29142
    • 29030

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!