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    Santee, SC Commercial Real Estate for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    15 results
    Highway Commercial Property with Storage
    $1,900,000
    3,282 SF

    Highway Commercial Property with Storage

    9158 Old Number Six Highway, Santee, SC 29142

    Commercial building with storage units near I-95 in Santee.

    • High visibility location near Highway 6 and I‑95.
    • Commercial property designed for two separate businesses.
    • 22 storage units at the rear of the property currently rented.
    • Second story suitable for offices or storage.
    • Located near Somerset homes and across from Santee‑Cooper Resort entrance.
    Updated: Jul 1, 2025
    View details
    Santee Commercial Land For Sale
    Contact for pricing
    0.47 Acres

    Santee Commercial Land For Sale

    Five Chop Road, Santee, SC 29142

    0.47-acre commercial parcel in high-traffic Santee corridor.

    • Located in a high‑traffic corridor between I‑95 and U.S. Route 301.
    • Strong visibility from Interstate 95.
    • 0.47‑acre wooded parcel.
    • Strategically located for investment.
    • Near the Lake Marion area.
    Updated: Mar 10
    View details
    Commercial Land in Santee, SC
    $289,900
    3.02 Acres

    Commercial Land in Santee, SC

    3.02 acres of commercially zoned land with road frontage.

    2212 State Park Road, Santee, SC 29142
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    Prime Santee Land Opportunity
    $1,500,000
    18.17 Acres

    Prime Santee Land Opportunity

    Highly visible 18-acre corner tract near I-95 in Santee, SC.

    Highway 301 & 15, Santee, SC 29142
    View details
    Prime Corner Lot in Santee
    $1,950,000
    22.04 Acres

    Prime Corner Lot in Santee

    Highly visible acreage near I-95, ideal for development.

    Highway 15 And 301, Santee, SC 29142
    View details
    Santee Cooper Resort Land
    $85,000
    0.54 Acres

    Santee Cooper Resort Land

    Land in gated golf community near Lake Marion.

    110 Cooper Drive unit: 7, Santee, SC 29142
    View details
    Santee Cooper Resort Land
    $85,000
    0.48 Acres

    Santee Cooper Resort Land

    Gated golf community lot near Lake Marion.

    128 Cooper Circle unit: 3, Santee, SC 29142
    View details
    Land in Established Santee Community
    $150,000
    5.00 Acres

    Land in Established Santee Community

    5-acre land parcel in an established Santee, SC community.

    Ellexlee Road, Santee, SC 29142
    View details
    Santee Commercial Land Near I-95
    $339,000

    Santee Commercial Land Near I-95

    4.65 acres of commercial land near I-95 in Santee, SC.

    656 Bass Drive, Santee, SC 29142
    View details
    Prime Commercial Land Near I-95
    $339,000
    1.51 Acres

    Prime Commercial Land Near I-95

    Shovel-ready land near I-95, ideal for retail development.

    676 Bass Dr, Santee, SC
    View details
    Freestanding Retail Property For Sale
    $1,394,000
    9,993 SF

    Freestanding Retail Property For Sale

    Freestanding retail property with investment-grade tenant Dollar Tree.

    100 Bass Dr, Santee, SC
    View details
    Commercial Land Near I-95
    $705,000
    3.14 Acres

    Commercial Land Near I-95

    Shovel-ready commercial land in high-traffic area near I-95.

    0 Bass Drive/Hwy 301, Santee, SC
    View details
    Drive-Thru Restaurant Ground Lease
    $2,152,000
    1,920 SF

    Drive-Thru Restaurant Ground Lease

    Net ground lease opportunity with experienced operator in Santee, SC.

    8832 Old Number Six Hwy, Santee, SC 29142
    View details
    Land Near Santee Development Ready
    $189,900
    21.00 Acres

    Land Near Santee Development Ready

    21 acre tract near Santee, SC, suitable for development.

    Graveyard Rock Road lot: 3, Santee, SC 29142
    View details
    Prime Commercial Land in Santee
    $705,000

    Prime Commercial Land in Santee

    Shovel-ready land near I-95, ideal for retail development.

    656 Bass Dr, Santee, SC 29142
    View details
    Based on your search, we've compiled 269 Potential Opportunities for your consideration. Besides 15 Active listings in Santee, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 250 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Downtown Elloree Mixed-Use Property
    $475,000
    6,060 SF

    Downtown Elloree Mixed-Use Property

    Commercial/Residential property with retail space and rental income potential.

    2701 Cleveland Street, Elloree, SC 29047
    View details
    Cleared Commercial Land For Sale
    $285,000
    3.88 Acres

    Cleared Commercial Land For Sale

    3.88 AC of cleared commercial land near major roads.

    2710 Old State Rd, Cameron, SC
    View details
    Cleared Commercial Land For Sale
    $105,000
    1.41 Acres

    Cleared Commercial Land For Sale

    1.41 AC corner parcel near I-26 & I-95.

    2718 Old State Rd, Cameron, SC
    View details
    Downtown Elloree Retail Building
    $145,000
    6,000 SF

    Downtown Elloree Retail Building

    Over 6,000 sqft retail building in downtown Elloree.

    2726 Cleveland St, Elloree, SC 29047
    View details

    Explore Off-Market Properties in Santee, SC

    Consider similar Off-Market properties in Santee, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    Hwy 6th 6

    Hwy 6th 6

    WHOLESALE OUTLET, DISCOUNT STORE • 10,168 SF
    Value Estimation
    $1,110,000
    Hwy 6th 6, Santee, SC 29142
    View details
    657 Bass Dr

    657 Bass Dr

    FINANCIAL BUILDING • 2,761 SF
    Value Estimation by Request
    657 Bass Dr, Santee, SC 29142
    View details
    8832 Old Number 6th Hwy

    8832 Old Number 6th Hwy

    MOTEL • 4,388 SF
    Value Estimation by Request
    8832 Old Number 6th Hwy, Santee, SC 29142
    View details
    8842 Old Number 6th Hwy

    8842 Old Number 6th Hwy

    OFFICE BUILDING • 1,003 SF
    Value Estimation by Request
    8842 Old Number 6th Hwy, Santee, SC 29142
    View details
    748 Bass Dr

    748 Bass Dr

    AUTO REPAIR, GARAGE • 2,400 SF
    Value Estimation by Request
    748 Bass Dr, Santee, SC 29142-8941
    View details
    8909 Old Number 6th Hwy

    8909 Old Number 6th Hwy

    CONVENIENCE STORE • 5,880 SF
    Value Estimation by Request
    8909 Old Number 6th Hwy, Santee, SC 29142-8606
    View details
    2202 Bass Dr

    2202 Bass Dr

    RETAIL STORES (PERSONAL SERVICES) • 2,028 SF
    Value Estimation by Request
    2202 Bass Dr, Santee, SC 29142
    View details
    8779 Old Number 6th Hwy

    8779 Old Number 6th Hwy

    OFFICE BUILDING • 1,944 SF
    Value Estimation
    $650,000
    8779 Old Number 6th Hwy, Santee, SC 29142
    View details
    800 Bass Dr

    800 Bass Dr

    RETAIL STORES (PERSONAL SERVICES) • 5,760 SF
    Value Estimation by Request
    800 Bass Dr, Santee, SC 29142-8923
    View details

    Santee, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 265 commercial real estate for sale in Santee, SC, showcased through 15 active listings on our real estate platform. These investment opportunities span a total of 3,103,650 square feet of properties for sale, with an estimated market value of $6,149,800.

    Sale prices for business properties in Santee, SC start at $85,000, averaging $768,725, and reaching up to $1,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Commercial real estate for Sale Near Santee, SC

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    Most Searched ZIP Codes in Santee, SC

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