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    Santee, SC
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    Santee, SC Commercial Real Estate for Sale

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    Vance, SC Summerton, SC Elloree, SC
    13 results
    Highway Commercial Property with Storage
    $1,900,000
    3,282 SF

    Highway Commercial Property with Storage

    9158 Old Number Six Highway, Santee, SC 29142

    Commercial building with storage units near I-95 in Santee.

    • High visibility location near Highway 6 and I‑95.
    • Commercial property designed for two separate businesses.
    • 22 storage units at the rear of the property currently rented.
    • Second story suitable for offices or storage.
    • Located near Somerset homes and across from Santee‑Cooper Resort entrance.
    Updated: Jul 1, 2025
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    Prime Santee Land Opportunity
    $1,255,000
    18.17 Acres

    Prime Santee Land Opportunity

    Highway 301 & 15, Santee, SC 29142

    18-acre corner tract near I-95 in Santee, SC.

    • Highly visible 18‑acre corner tract at the intersection of Highways 301 and 15, offering outstanding exposure.
    • Located just off I‑95 (Exit 97) in Santee, SC, providing easy access to major transportation routes.
    • Proximity to Lake Marion recreation and golf courses, enhancing the area's appeal.
    • Comprised of five contiguous parcels, offering flexibility for development.
    • Primarily open and tillable land with minimal wooded area, simplifying development.
    Updated: Feb 2
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    Prime Corner Lot in Santee
    $1,545,000
    22.04 Acres

    Prime Corner Lot in Santee

    Highly visible acreage near I-95, ideal for development.

    Highway 15 And 301, Santee, SC 29142
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    Freestanding Retail Property For Sale
    $1,394,000
    9,993 SF

    Freestanding Retail Property For Sale

    Freestanding retail property with investment-grade tenant Dollar Tree.

    100 Bass Dr, Santee, SC
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    Santee Commercial Land For Sale
    Contact for pricing
    0.47 Acres

    Santee Commercial Land For Sale

    0.47-acre commercial parcel in high-traffic Santee corridor.

    Five Chop Road, Santee, SC 29142
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    Prime Commercial Land Near I-95
    $705,000
    1.51 Acres

    Prime Commercial Land Near I-95

    Shovel-ready land near I-95, ideal for retail development.

    676 Bass Dr, Santee, SC
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    Land in Established Santee Community
    $150,000
    5.00 Acres

    Land in Established Santee Community

    5-acre land parcel in an established Santee, SC community.

    Ellexlee Road, Santee, SC 29142
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    Santee Commercial Land Near I-95
    $339,000

    Santee Commercial Land Near I-95

    4.65 acres of commercial land near I-95 in Santee, SC.

    656 Bass Drive, Santee, SC 29142
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    Santee Cooper Resort Land
    $85,000
    0.54 Acres

    Santee Cooper Resort Land

    Land in gated golf community near Lake Marion.

    110 Cooper Drive, Santee, SC 29142
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    Santee Cooper Resort Land
    $85,000
    0.48 Acres

    Santee Cooper Resort Land

    Gated golf community lot near Lake Marion.

    128 Cooper Circle, Santee, SC 29142
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    Drive-Thru Restaurant Ground Lease
    $2,152,000
    1,920 SF

    Drive-Thru Restaurant Ground Lease

    Net ground lease opportunity with experienced operator in Santee, SC.

    8832 Old Number Six Hwy, Santee, SC 29142
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    Commercial Land Near I-95
    $705,000
    3.14 Acres

    Commercial Land Near I-95

    Shovel-ready commercial land in high-traffic area near I-95.

    0 Bass Drive/Hwy 301, Santee, SC
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    Land Near Santee Development Ready
    $189,900
    21.00 Acres

    Land Near Santee Development Ready

    21 acre tract near Santee, SC, suitable for development.

    Graveyard Rock Road lot: 3, Santee, SC 29142
    View details
    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 13 Active listings in Santee, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 59 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Lakefront Land on Lake Marion
    $699,000
    2.20 Acres

    Lakefront Land on Lake Marion

    2.2 acres with 487 feet of pristine waterfront.

    3226 Francis Marion Boulevard, Summerton, SC 29148
    View details
    Downtown Elloree Mixed-Use Property
    $475,000
    6,060 SF

    Downtown Elloree Mixed-Use Property

    Commercial/Residential property with retail space and rental income potential.

    2701 Cleveland Street, Elloree, SC 29047
    View details
    Elloree Land Near Lake Marion
    $120,000
    6.43 Acres

    Elloree Land Near Lake Marion

    6.4-acre tract near Elloree, SC, close to Lake Marion.

    Old Hwy 6, Elloree, SC 29047
    View details
    Lake Marion Waterfront Development Opportunity
    $3,500,000
    3,200 SF

    Lake Marion Waterfront Development Opportunity

    2.255-acre waterfront parcel on Lake Marion with development potential.

    2110 Princess Pond Road, Summerton, SC 29148
    View details

    Off-Market Properties in Santee, SC

    Consider similar Off-Market properties in Santee, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    Hwy 6th 6
    WHOLESALE OUTLET, DISCOUNT STORE
    10,168 SF Lot: 1.78 Acres
    Estimated value
    $1,110,000

    Hwy 6th 6, Santee, SC 29142

    View details
    657 Bass Dr
    FINANCIAL BUILDING
    2,761 SF Lot: 0.88 Acres
    Value Estimation by Request

    657 Bass Dr, Santee, SC 29142

    View details
    8832 Old Number 6th Hwy
    MOTEL
    4,388 SF Lot: 1.30 Acres

    8832 Old Number 6th Hwy, Santee, SC 29142

    View details
    8842 Old Number 6th Hwy
    OFFICE BUILDING
    1,003 SF Lot: 0.41 Acres
    Value Estimation by Request

    8842 Old Number 6th Hwy, Santee, SC 29142

    View details
    748 Bass Dr
    AUTO REPAIR, GARAGE
    2,400 SF Lot: 0.92 Acres
    Value Estimation by Request

    748 Bass Dr, Santee, SC 29142-8941

    View details
    8909 Old Number 6th Hwy
    CONVENIENCE STORE
    5,880 SF Lot: 1.28 Acres
    Value Estimation by Request

    8909 Old Number 6th Hwy, Santee, SC 29142-8606

    View details
    2202 Bass Dr
    RETAIL STORES (PERSONAL SERVICES)
    2,028 SF Lot: 0.71 Acres
    Value Estimation by Request

    2202 Bass Dr, Santee, SC 29142

    View details
    8779 Old Number 6th Hwy
    OFFICE BUILDING
    1,944 SF Lot: 0.30 Acres
    Estimated value
    $650,000

    8779 Old Number 6th Hwy, Santee, SC 29142

    View details
    800 Bass Dr
    RETAIL STORES (PERSONAL SERVICES)
    5,760 SF Lot: 0.82 Acres
    Value Estimation by Request

    800 Bass Dr, Santee, SC 29142-8923

    View details
    Hutch Dr
    COMMERCIAL (GENERAL)
    12,000 SF Lot: 5.00 Acres
    Estimated value
    $1,320,000

    Hutch Dr, Santee, SC 29142

    View details
    Hwy 301
    OFFICE BUILDING
    3,948 SF Lot: 1.02 Acres
    Value Estimation by Request

    Hwy 301, Santee, SC 29142

    View details

    Santee, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Santee, SC, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 15,199 square feet of properties for sale, with an estimated market value of $5,785,000.

    Sale prices for business properties in Santee, SC start at $339,000, averaging $1,446,250, and reaching up to $2,152,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 4,658
    Population Growth (5Y) -10.2%
    Median Household Income $50,673
    College Educated 32.1%

    High-Yield Neighborhoods for Investment

    Identify Santee submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    29142 $770.1K

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