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Greenville County, SC Commercial Real Estate for Sale

721 results
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Powdersville Office Building with Retail Potential
$449,000
0.31 Acres

Powdersville Office Building with Retail Potential

3127 Highway 153, Piedmont, SC 29673

2,016 SF office building with retail potential in Powdersville.

  • High‑exposure location with over 200 feet of frontage on Highway 153.
  • Retail potential in addition to office use.
  • Fully handicap accessible with dedicated handicap parking spaces.
  • Median break on Highway 153 allows easy access from both directions.
  • Includes 6 office spaces, 2 restrooms, kitchen, meeting room, and storage.
Updated: Nov 12, 2025
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Retail Space on Saluda Lake
$499,900
0.28 Acres

Retail Space on Saluda Lake

738 Saluda Lake Rd, Greenville, SC 29611

Retail property on 0.28 acres with road frontage.

  • Includes both the business and the building.
  • Strategically located on Saluda Lake Road in a fast‑growing area.
  • .28 acres of level property.
  • Ample parking available.
  • Approximately 81 feet of road frontage on Saluda Lake Road.
Updated: Jul 31, 2025
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Office Building with Billboard Income
$398,500
0.47 Acres

Office Building with Billboard Income

Office property in Greenville, SC with additional billboard income.

1908 N Pleasantburg Dr, Greenville, SC 29609
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Office For Sale Greenville
$935,000
0.25 Acres

Office For Sale Greenville

Office property available for purchase in Greenville, South Carolina.

204 Mills Ave, Greenville, SC 29605
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Eastside Greenville Office Space Available
Contact for pricing
0.10 Acres

Eastside Greenville Office Space Available

Well-maintained office space in a desirable Greenville location.

4010 E North St, Greenville, SC 29615
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Greer Office with Fireplace
$502,000
1,799 SF

Greer Office with Fireplace

Professional office space near downtown Greer with fireplace and ample space.

408 North Main St, Greer, SC 29651
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Commercial Property in Greenville, SC
$335,000
2.00 Acres

Commercial Property in Greenville, SC

Commercial property for sale in Greenville, South Carolina.

50 Gladys Dr, Greenville, SC 29607
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Poinsett Highway Commercial Opportunity
$1,500,000
1.07 Acres

Poinsett Highway Commercial Opportunity

Two buildings on Poinsett Highway with high visibility and versatility.

2518 Poinsett Hwy, Greenville, SC 29609
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New Commercial Unit For Lease
Contact for pricing
2,500 SF

New Commercial Unit For Lease

Brand new commercial unit with versatile space available for lease.

1 Brookside Unit 2 Dr, Travelers Rest, SC 29690
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Downtown Greenville Commercial Building
$275,000
0.06 Acres

Downtown Greenville Commercial Building

Commercial building in downtown Greenville, SC, zoned MX-2.

E Stone Ave, Greenville, SC 29601
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Mixed-Use Commercial Property on White Horse
$440,900
0.35 Acres

Mixed-Use Commercial Property on White Horse

Versatile property with retail, office, and auto service potential.

6035 White Horse Road Ext, Greenville, SC 29611
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Charming Cleveland Cafe and Store
$650,000
1.00 Acre

Charming Cleveland Cafe and Store

Turnkey cafe and general store in scenic mountain foothills.

4000 Geer Hwy, Cleveland, SC 29635
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Updated Office Building in Simpsonville
$1,800,000
0.18 Acres

Updated Office Building in Simpsonville

Updated 2,907 SF building in the heart of Downtown Simpsonville.

131 SE Main St, Simpsonville, SC 29691
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Greenville Retail Storefront with Landmark Mural
$550,000
0.19 Acres

Greenville Retail Storefront with Landmark Mural

Retail storefront in high-traffic location with flexible C-2 zoning.

1714 Easley Bridge Rd, Greenville, SC 29611
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Downtown Greenville Office Space Available
Contact for pricing
1.00 Acre

Downtown Greenville Office Space Available

Office suites available in downtown Greenville, utilities included.

1010 E North St, Greenville, SC 29601
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Greenville Office Near Medical Facilities
$950,000
0.35 Acres

Greenville Office Near Medical Facilities

Premium office space with subdivision potential near Prisma Health.

101 Chapman St, Greenville, SC 29605
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Refreshed Office Building in Greenville
Contact for pricing
0.12 Acres

Refreshed Office Building in Greenville

Refreshed commercial office building in a prime Greenville location.

604 University Rdg, Greenville, SC 29601
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Greenville Commercial Building For Sale
$599,500
0.28 Acres

Greenville Commercial Building For Sale

Commercial building with fenced rear yard in Greenville, SC.

4 S Washington Ave, Greenville, SC 29611
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Commercial Building on Geer Hwy
$275,000
0.18 Acres

Commercial Building on Geer Hwy

Commercial building with ample parking and storage on Geer Hwy.

3037 Geer Hwy, Marietta, SC 29661
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Retail Space on 1.91 Acres
$875,000
1.90 Acres

Retail Space on 1.91 Acres

Retail property on 1.91 acres in Greenville, South Carolina.

738 Saluda Lake Rd, Greenville, SC 29611
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Greer Commercial Property with Garage
$355,000
0.44 Acres

Greer Commercial Property with Garage

Commercial property with auto garage in prime Greer location.

110 Conway Dr, Greer, SC 29651
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Retail Property Near Heritage Park
$889,000
1.27 Acres

Retail Property Near Heritage Park

Well-maintained retail property near Heritage Park and downtown Simpsonville.

827A SE Main St, Simpsonville, SC 29680
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Greenville Flex Industrial/Commercial Property
$1,100,000
0.69 Acres

Greenville Flex Industrial/Commercial Property

8,550 SF flex building in Donaldson Center area.

7 Akron Dr, Greenville, SC 29605
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Professional Office Suite on Pelham
Contact for pricing
0.44 Acres

Professional Office Suite on Pelham

First floor office suite available for sublease through February 2029.

330B Pelham Rd, Greenville, SC 29615
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Greenville County, SC Commercial Real Estate Investment Opportunities Market Analysis

Explore 5000+ commercial real estate investment opportunities in Greenville County, SC with 721 listings featured on our commercial real estate marketplace. The current inventory includes 996,994,923 square feet of properties with an estimated value of $5,143,328,320.

Estimated prices for commercial real estate in Greenville County, SC begin at $30,000, with an average of $772,619 and extend to $25,000,000.

In Greenville County, SC, current investment values show:

  • Retail properties positioned at $737,845
  • Office Properties & Spaces measuring $853,109
  • Other commercial real estate assessed at $724,516
  • Industrial properties calculated at $903,142
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