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    South Carolina Commercial Real Estate for Sale

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    5,568 properties
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    Integrated Heart Center Medical Facility
    Integrated Heart Center Medical Facility

    8 Richland Medical Park Dr, Columbia, SC 29203

    Contact for pricing
    96,190 sqft

    Advanced heart center integrated into Prisma Health Heart Hospital; new roof installed in Q1 2026.

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    Commercial Land Near I-85
    Commercial Land Near I-85

    540 Shelby Highway, Gaffney, SC 29341

    $300,000

    A vacant corner parcel at Exit 96 offers a commercial site along the I-85 corridor in Gaffney.

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    Working Cattle Ranch With Infrastructure
    Working Cattle Ranch With Infrastructure

    1647 Smoak Road, Walterboro, SC 29488

    $1,600,000
    201.24 AC lot

    Established agricultural property with grazing improvements, wooded acreage, trails, water systems, and a permitted future homesite.

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    Commercial Land with Existing Improvements
    Commercial Land with Existing Improvements

    1865 State Road, Summerville, SC 29486

    $1,875,000

    High-exposure tract with an existing residence and storage building, positioned along a growing regional commercial corridor.

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    Signalized-Corner Commercial Land
    Signalized-Corner Commercial Land

    202 Edgefield Road, North Augusta, SC 29841

    $495,000
    0.74 AC lot

    Assemblage of level parcels with public water and sewer in a developed commercial and residential corridor.

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    95-Bed Residential Care Facility
    95-Bed Residential Care Facility

    4206 Moore Duncan Highway, Moore, SC 29369

    $4,250,000
    3.50 AC lot

    Turn-key assisted living facility with 95 beds across five single-floor buildings on a sizable campus.

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    C1 Commercial Land with Parking
    C1 Commercial Land with Parking

    312 E Broad St., Hemingway, SC 29554

    $185,000
    1.80 AC lot

    C1-zoned commercial parcel with existing blacktop parking and a pylon sign.

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    Agricultural Land Tracts
    Agricultural Land Tracts

    01 Hagood Mill Road, Pickens, SC 29671

    $179,000
    25.00 AC lot

    Five roughly 5-acre tracts are offered for sale, allowing room to build and support small-scale farm use.

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    Fenced Agricultural Land
    Fenced Agricultural Land

    1049 Culp Ferguson Road, Lancaster, SC 29720

    $2,775,000
    84.67 AC lot

    Fenced farmland features open fields, pastures, wooded buffers, rolling terrain, and a pond.

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    Hobby Lobby & Kohl’s Anchored Center
    Hobby Lobby & Kohl’s Anchored Center

    1528 Meeting Blvd, Rock Hill, SC 29730

    Contact for pricing
    132,343 sqft

    Multi-tenant retail shopping center anchored by Hobby Lobby and Kohl’s in the Rock Hill, SC retail trade area.

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    Auto Shop with Fenced Yard
    Auto Shop with Fenced Yard

    4 S Washington Avenue, Greenville, SC 29611

    $525,000
    0.28 AC lot

    C-2 highway commercial property with masonry construction, concrete flooring, and a secured rear yard.

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    Commercial Corner Lot with Building
    Commercial Corner Lot with Building

    1425 W Market Street, Anderson, SC 29624

    $89,000
    0.29 AC lot

    The parcel includes a three-room structure with fire and smoke damage and a small bathroom.

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    Mixed-Use Development Lot
    Mixed-Use Development Lot

    25 Maiden Lane, Bluffton, SC 29910

    $450,000

    Create a business with living space near Bluffton’s dining, shopping, waterways, and boat access.

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    Three-Level Live-Work Property
    Three-Level Live-Work Property

    4327 Old Mill Road, Anderson, SC 29623

    $750,000
    0.48 AC lot

    Flexible layout combines residential accommodations with office and flex areas.

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    Multiplex-Ready Residential Development Land
    Multiplex-Ready Residential Development Land

    Rice Street, Latta, SC 29565

    $45,000
    3.88 AC lot

    Nearly 4 acres in Latta with city water and sewer, offering flexible development options for residential or small multifamily uses.

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    Relocatable Specialty Building
    Relocatable Specialty Building

    Lot 12 Easley Bridge Road, Greenville, SC 29611

    $300,000

    The building may be moved at the purchaser’s expense.

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    Innovation District Commercial Land
    Innovation District Commercial Land

    Harrison Bridge Road, Simpsonville, SC 29680

    $873,910
    2.81 AC lot

    Commercial land with available utilities near the Harrison Bridge Road and Fairview Road intersection.

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    Commercial Land Parcel
    Commercial Land Parcel

    00 Five Chop Road, Elloree, SC 29047

    Contact for pricing
    52,272 sqft

    Residential-zoned commercial land located along Hwy 301, positioned for billboard use consideration.

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    Flex Space with Garage
    Flex Space with Garage

    1010 5th Ave. N Suite 106, Surfside Beach, SC 29575

    Contact for pricing
    8,498 sqft

    Office, kitchenette, and restroom with shower complement the garage and storage area.

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    Historic Mixed-Use Downtown Building
    Historic Mixed-Use Downtown Building

    302 Park Avenue SE, Aiken, SC 29801

    $2,500,000

    Two-story law office, renovated salon suite, street-level storefront, detached annex office, and a one-bedroom condominium.

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    Church Facility with Flex Rooms
    Church Facility with Flex Rooms

    911 Main St, Wellford, SC 29385

    $50,000
    1,883 sqft

    A reconfigurable interior includes an open gathering room, kitchen area, two bathrooms, and central HVAC.

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    Commercial Land with Road Frontage
    Commercial Land with Road Frontage

    Whittaker Parkway, Orangeburg, SC 29115

    $299,000
    12.46 AC lot

    Commercial tract with public water and multiple access points for future development.

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    Commercial Land with Existing Improvements
    Commercial Land with Existing Improvements

    4516 Augusta Highway, Gilbert, SC 29054

    $1,100,000

    The parcel includes a house, a metal storage building, and a mobile home, with city water on site.

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    Warehouse with Rail Docks
    Warehouse with Rail Docks

    653 Sc Highway 121, Johnston, SC 29832

    Contact for pricing
    24,000 sqft

    Industrial warehouse offering multiple loading options, a fenced roadside yard, and additional laydown space.

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