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South Carolina

Hampton County, SC Commercial Real Estate for Sale

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Columbia, SC Greenville, SC Spartanburg, SC Aiken, SC Anderson, SC Rock Hill, SC Myrtle Beach, SC Charleston, SC

28 properties

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Versatile Commercial Property in Yemassee

Updated: Jan 18

Versatile Commercial Property in Yemassee

84 Salkehatchie Road, Yemassee, SC 29945

$293,000

1,638 sqft 0.28 AC lot

Prime commercial location on Salkehatchie Road in Yemassee with Office Commercial District (OCD) zoning, offering versatile business/investment opportunities.
1638 sq ft main floor plus a fully finished 605 sq ft basement with interior and separate exterior access, a rare feature.
Recent system upgrades including a new roof and new HVAC.
Currently operated as a short‑term rental with established income history.
Flexible floor plan supports a range of layout options.

Varnville Commercial Building with Roll-Up Doors

Updated: Apr 4

Varnville Commercial Building with Roll-Up Doors

835 E Palmetto Avenue, Varnville, SC 29944

$169,900

2,800 sqft 1.04 AC lot

Double roll doors on each side for easy access and efficient loading/unloading.
Approximately 70x40 building suitable for a variety of commercial purposes.
Located in Varnville near I‑95, providing convenient access to transportation routes.
1.037 acre lot with ample room for parking.
Includes dedicated office space for administrative tasks.

Yemassee Commercial Property For Sale

Yemassee Commercial Property For Sale

84 Salkehatchie Road, Yemassee, SC 29945

$293,000

1,638 sqft 0.28 AC lot

Commercial property in Yemassee, SC with flexible business or investment uses.

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Industrial Redevelopment Opportunity

Industrial Redevelopment Opportunity

304 Hoover Street N, Hampton, SC 29924

$2,500,000

770,000 sqft 55.00 AC lot

Prime 55-acre industrial site with rail access and incentives.

Multi-Office Building

Multi-Office Building

301 1st Street E, Hampton, SC 29924

$199,000

0.16 AC lot

For sale commercial office building configured for multiple offices with two restrooms and a kitchenette.

Turnkey Restaurant with Taco Truck

Turnkey Restaurant with Taco Truck

104 Lee Avenue, Hampton, SC 29924

$190,000

0.11 AC lot

Fully operational taqueria with loyal following and included taco truck.

Commercial Storefront in Hampton, SC

Commercial Storefront in Hampton, SC

622 Mulberry Street, Hampton, SC 29924

$80,000

2,400 sqft

Corner commercial building in high-traffic area, ideal for business.

Combahee River RV Park Opportunity

Combahee River RV Park Opportunity

16703 Hendersonville Highway, Yemassee, SC 29945

$1,100,000

4.00 AC lot

RV park on 4+ acres with river access.

Yemassee Commercial Truck Terminal

Yemassee Commercial Truck Terminal

1334 Simmons Street, Yemassee, SC 29945

Contact for pricing

18,952 sqft

Truck terminal with warehouse, office, and shop space for sale.

Agricultural Hunting Tract with Homesite

Agricultural Hunting Tract with Homesite

2650 Joe Miley Road, Brunson, SC 29911

$675,000

50.36 AC lot

An agricultural property with a cleared 1.5-acre homesite supported by septic and water permits and an updated plat.

Commercial Property Near Interstate Exit

Commercial Property Near Interstate Exit

61 Charles Frazier Cir, Yemassee, SC 29945

$295,000

1,125 sqft 1.30 AC lot

1.3-acre commercial property with high visibility and convenient access.

Historic Event Center Building

Historic Event Center Building

100 Lightsey Street, Hampton, SC 29924

$297,000

0.51 AC lot

Built in the 1940s and partially renovated for event center use, with split AC units throughout.

Historic Event Center Building

Historic Event Center Building

100 Lightsey Street, Hampton, SC 29924

$274,000

Built in the 1940s and partially renovated for an event center, with split AC units throughout.

Estill Biodiesel Refinery for Sale

Estill Biodiesel Refinery for Sale

519 3rd St, Estill, SC 29918

$3,200,000

8.99 AC lot

8.99-acre biodiesel refinery with rail access and significant storage capacity.

General Commercial Retail Building

General Commercial Retail Building

61 Charles Frazier Circle, Yemassee, SC 29945

$295,000

1,125 sqft 1.30 AC lot

A 1,125-square-foot retail building on two combined lots offers General Commercial zoning and convenient access near major highways.

Commercial Lot Ready for Building

Commercial Lot Ready for Building

201 Elm Street W, Hampton, SC 29924

$89,900

0.50 AC lot

Commercial lot near downtown and courthouse in Hampton, SC.

Industrial Land Near I-95

Industrial Land Near I-95

SC-68, Yemassee, SC 29945

Contact for pricing

1,625.00 AC lot

1,625 acre industrial land tract in Hampton County, South Carolina.

Commercial Acreage in Hampton County

Commercial Acreage in Hampton County

625 Elm Street W, Hampton, SC 29924

$365,000

4.06 AC lot

Commercial acreage suitable for an outparcel plaza on busy Hwy.

Varnville Retail Property on Highway

Varnville Retail Property on Highway

Yemassee Highway, Varnville, SC 29944

$75,000

1,300 sqft 0.68 AC lot

Retail property with store, barn, and shed on large lot.

Commercial Acreage in Hampton County

Commercial Acreage in Hampton County

625 Elm Street W, Hampton, SC 29924

$365,000

4.06 AC lot

Commercial land for outparcel plaza on busy Hwy 278.

Farm and Hunting Land with Pond

Farm and Hunting Land with Pond

1586 Fisher Rd, Varnville, SC 29944

$149,995

9.75 AC lot

Mostly open agricultural fields with shallow pond and paved road frontage, suited for farming, recreation, or a cabin site.

I-95 Development Opportunity, Yemassee

I-95 Development Opportunity, Yemassee

Hwy 21, Yemassee, SC 29945

$689,000

8.80 AC lot

8.8 acres of commercial land with I-95 frontage.

Yemassee Commercial Land For Sale

Yemassee Commercial Land For Sale

3296 Point S Drive, Yemassee, SC 29945

$300,000

1.24 AC lot

Highly visible 1.24 acre commercial land near I-95.

Commercial Land in Hampton, SC

Commercial Land in Hampton, SC

108 Lee Avenue, Hampton, SC 29924

Contact for pricing

0.10 AC lot

Commercial land available in Hampton, South Carolina.

Hampton County, SC Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Hampton County, SC, showcased through 28 active listings on our real estate platform. These investment opportunities span a total of 783,326 square feet of properties for sale, with an estimated market value of $4,075,900.

Sale prices for business properties in Hampton County, SC start at $75,000, averaging $452,877, and reaching up to $2,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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