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    Chillicothe, OH Commercial Real Estate for Sale

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    23 results
    Commercial Land in Bustling Corridor
    $525,000
    3.72 Acres

    Commercial Land in Bustling Corridor

    0 Pawnee Road, Chillicothe, OH 45601

    3.72-acre commercial parcel in Chillicothe's heart, primed for development.

    • 3.72‑acre commercial parcel in Chillicothe's commercial corridor
    • Dual access points from Bridge Street and Pawnee Road
    • Flat, undeveloped land
    • Suitable for retail centers
    • Suitable for office buildings
    Updated: Mar 4
    View details
    High-Traffic Commercial Property in Chillicothe
    $169,900
    1,496 SF

    High-Traffic Commercial Property in Chillicothe

    945 E Main Street, Chillicothe, OH 45601

    Versatile commercial building on East Main Street with high visibility.

    • High‑traffic location on East Main Street in Chillicothe.
    • Versatile building suitable for office, retail, or studio.
    • Large glass storefront providing excellent natural light and signage exposure.
    • Numerous off‑street parking spaces.
    • Large, open‑concept layout offering a blank canvas for customization.
    Updated: Apr 7
    View details
    Renovated Commercial Property on Western
    $399,000
    1,848 SF

    Renovated Commercial Property on Western

    Updated commercial property on Western Avenue in Chillicothe, Ohio.

    2111 Western Ave., Chillicothe, OH 45601
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    Mixed-Use Asset in Chillicothe, OH
    $239,000

    Mixed-Use Asset in Chillicothe, OH

    Versatile mixed-use property with income potential and repositioning opportunities.

    83-85 Main Street, Chillicothe, OH 45601
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    Main Street Investment Opportunity
    $550,000
    5,244 SF

    Main Street Investment Opportunity

    High-visibility commercial building with established tenants in a prime location.

    946-954 E Main Street, Chillicothe, OH 45601
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    Prime Retail Ground Lease Opportunity
    Contact for pricing
    1.35 Acres

    Prime Retail Ground Lease Opportunity

    1.35 acre commercial land in high-traffic retail corridor.

    1487 Bridge Street, Chillicothe, OH 45601
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    Commercial Land on US-23
    $325,000
    7.86 Acres

    Commercial Land on US-23

    7.86 acre commercial parcel with high visibility on US-23.

    US-23, Chillicothe, OH 45601
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    Versatile Land in Chillicothe, OH
    $350,000
    20.90 Acres

    Versatile Land in Chillicothe, OH

    Land with commercial, agricultural, and subdivision potential.

    13223 Pleasant Valley Road, Chillicothe, OH 45601
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    Versatile Land in Chillicothe, OH
    $950,000
    40.00 Acres

    Versatile Land in Chillicothe, OH

    Multi-use land with road frontage and utilities in Chillicothe.

    13223 Pleasant Valley Road, Chillicothe, OH 45601
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    Chillicothe Equestrian Estate For Sale
    $574,000
    2,400 SF

    Chillicothe Equestrian Estate For Sale

    11.8-acre mini equestrian estate near Chillicothe, Ohio.

    141 Delano Rd., Chillicothe, OH 45601
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    Retail Space on Bridge Street
    Contact for pricing

    Retail Space on Bridge Street

    NNN lease opportunity in Chillicothe, with high visibility.

    27 Bridge Street, Chillicothe, OH 45601
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    Downtown Chillicothe Mixed-Use Building
    $214,900
    2,200 SF

    Downtown Chillicothe Mixed-Use Building

    Versatile building in historic downtown Chillicothe with retail and residential/office potential.

    13 W 2ND ST, Chillicothe, OH 45602
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    Renovated Mixed-Use Building For Sale
    $650,000
    4,832 SF

    Renovated Mixed-Use Building For Sale

    Renovated mixed-use building with high visibility and ample parking.

    7 Saint Andrews Blvd, Chillicothe, OH 45601
    View details
    Downtown Chillicothe Mixed-Use Investment
    $214,900
    2,200 SF

    Downtown Chillicothe Mixed-Use Investment

    Versatile building in historic Union Block with retail and residential potential.

    11 W 2ND ST, Chillicothe, OH 45601
    View details
    Commercial Land on US Route
    $325,000
    7.86 Acres

    Commercial Land on US Route

    7.86-acre commercial parcel with high visibility on US Route 23.

    US Rt 23, Chillicothe, OH 45601
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    Buildable Land in Adena School
    $175,000
    10.00 Acres

    Buildable Land in Adena School

    10 flat acres ideal for building or recreation.

    14839 Westfall Road LOT 20, Chillicothe, OH 45601
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    Tim Hortons | White Castle Lease
    $2,020,000
    5,424 SF

    Tim Hortons | White Castle Lease

    Ground lease investment with long-term tenants in prime location.

    1000-1020 N Bridge St, Chillicothe, OH 45601
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    Prime Retail Site on Western
    $439,000

    Prime Retail Site on Western

    0.71-acre retail site with high traffic and visibility.

    1318 Western Ave, Chillicothe, OH 45601
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    31.26 Acre Industrial Development Site
    Contact for pricing

    31.26 Acre Industrial Development Site

    Shovel-ready industrial site with rail access and utilities.

    33630 Old Route 35, Chillicothe, OH 45601
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    Prime Land Near Fairgrounds
    Contact for pricing
    9.06 Acres

    Prime Land Near Fairgrounds

    High visibility land ideal for commercial or mixed-use development.

    Fairgrounds Rd, Chillicothe, OH
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    Renovated Commercial Property on Western
    $300,000
    1,848 SF

    Renovated Commercial Property on Western

    Renovated commercial property on busy Western Ave in Chillicothe.

    2111 Western Avenue, Chillicothe, OH 45601
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    New Chipotle with Drive-Thru
    $2,552,631
    2,325 SF

    New Chipotle with Drive-Thru

    New Chipotle with drive-thru in growing Ross County.

    6 St Andrews Blvd, Chillicothe, OH
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    Two-Tenant Retail Building For Sale
    $5,801,000
    72,010 SF

    Two-Tenant Retail Building For Sale

    Two-tenant retail building with long-term leases in Chillicothe, Ohio.

    1470 N Bridge St, Chillicothe, OH
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 23 Active Listings in Chillicothe, OH, we suggest to view alternatives - similar 2005 Off-Market properties to explore as potential leads.

    Explore Off-Market Properties in Chillicothe, OH

    Consider similar Off-Market properties in Chillicothe, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    19 2nd St

    19 2nd St

    RETAIL STORES (PERSONAL SERVICES) • 1,000 SF
    Value Estimation by Request
    19 2nd St, Chillicothe, OH 45601-3111
    View details

    Chillicothe, OH Commercial Real Estate Investment Opportunities Market Analysis

    Explore 2028 commercial real estate for sale in Chillicothe, OH, showcased through 23 active listings on our real estate platform. These investment opportunities span a total of 99,979 square feet of properties for sale, with an estimated market value of $13,047,331.

    Sale prices for business properties in Chillicothe, OH start at $169,900, averaging $1,304,733, and reaching up to $5,801,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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