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    Chillicothe, OH
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    Chillicothe, OH Retail Space for Sale

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    Kingston, OH Londonderry, OH South Salem, OH
    Downtown Chillicothe Mixed-Use Building
    $214,900
    2,200 SF
    Downtown Chillicothe Mixed-Use Building

    13 W 2ND ST, Chillicothe, OH 45602

    Versatile building in historic downtown Chillicothe with retail and residential/office potential.
    • Prime downtown Chillicothe location on the historic Union Block.
    • High‑visibility retail space on the main level for steady foot traffic.
    • Mixed‑use potential: retail space plus apartment or office space upstairs.
    • Opportunity to generate additional income from upstairs space.
    • Charming historic details.
    Updated: Sep 3, 2025
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    Renovated Mixed-Use Building For Sale
    $650,000
    4,832 SF
    Renovated Mixed-Use Building For Sale

    7 Saint Andrews Blvd, Chillicothe, OH 45601

    Renovated mixed-use building with high visibility and ample parking.
    • High traffic count of 20,000 vehicles per day and strong visibility due to its LOCATION ON HISTORIC US ROUTE 50.
    • 4,832 SF FULLY RENOVATED mixed‑use building suitable for commercial or residential re‑development.
    • Zoned commercial, offering significant potential for various business ventures.
    • Prime retail location adjacent to the Chillicothe Country Club and near established businesses like Chipotle and Bob Evans.
    • Ample paved parking lot for customers and employees.
    Updated: Jan 27
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    Downtown Chillicothe Mixed-Use Investment
    $214,900
    2,200 SF
    Downtown Chillicothe Mixed-Use Investment

    Versatile building in historic Union Block with retail and residential potential.

    11 W 2ND ST, Chillicothe, OH 45601

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    Prime Retail Ground Lease Opportunity
    Contact for pricing
    1.35 Acres
    Prime Retail Ground Lease Opportunity

    1.35 acre commercial land in high-traffic retail corridor.

    1487 Bridge Street, Chillicothe, OH 45601

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    Retail Space on Bridge Street
    Contact for pricing
    Retail Space on Bridge Street

    NNN lease opportunity in Chillicothe, with high visibility.

    27 Bridge Street, Chillicothe, OH 45601

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    Based on your search, we've compiled 77 Potential Opportunities for your consideration. Besides 5 Active listings in Chillicothe, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 67 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Commercial Space on Corner Lot
    $240,000
    8,752 SF
    Versatile Commercial Space on Corner Lot

    8752 sq ft commercial space on busy corner lot.

    2758 State Route 41, Bainbridge, OH 45612

    View details
    Retail Space with Drive-Thru Canopy
    $250,000
    2,520 SF
    Retail Space with Drive-Thru Canopy

    2,520 SF retail space with finished lower level.

    125 Jefferson Street, Greenfield, OH 45123

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    Versatile Commercial Space on State Route
    $250,000
    8,752 SF
    Versatile Commercial Space on State Route

    Corner lot commercial building suitable for warehouse, retail, or office.

    2758 State Route 41 S, Bainbridge, OH 45612

    View details
    Spacious Retail Space For Sale
    $180,000
    6,000 SF
    Spacious Retail Space For Sale

    6000+ sq ft retail space, great location, motivated seller.

    1026 Jefferson Street, Greenfield, OH 45123

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime PUD-Zoned Land Opportunity
    $1,599,000
    900 SF
    Prime PUD-Zoned Land Opportunity

    2.07 acres of PUD-zoned land in a growing corridor.

    3229 State Road 207, Elkton, FL 32033

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    Off-Market Properties in Chillicothe, OH

    Consider similar Off-Market properties in Chillicothe, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    19 2nd St
    RETAIL STORES (PERSONAL SERVICES)
    1,000 SF Lot: 0.03 Acres
    Value Estimation by Request

    19 2nd St, Chillicothe, OH 45601-3111

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    19 2nd St
    RETAIL STORES (PERSONAL SERVICES)
    2,400 SF Lot: 0.01 Acres
    Value Estimation by Request

    19 2nd St, Chillicothe, OH 45601-2524

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    1050 Main St
    RETAIL STORES (PERSONAL SERVICES)
    9,100 SF Lot: 1.08 Acres
    Estimated value
    $1,540,000

    1050 Main St, Chillicothe, OH 45601-2848

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    20 Main St
    RETAIL STORES (PERSONAL SERVICES)
    1,482 SF Lot: 0.06 Acres
    Value Estimation by Request

    20 Main St, Chillicothe, OH 45601-2503

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    375 Marietta Rd
    RETAIL STORES (PERSONAL SERVICES)
    1,704 SF Lot: 0.70 Acres

    375 Marietta Rd, Chillicothe, OH 45601-9433

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    31 Paint St
    RETAIL STORES (PERSONAL SERVICES)
    1,136 SF Lot: 0.08 Acres
    Value Estimation by Request

    31 Paint St, Chillicothe, OH 45601-3211

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    1404 Brg St
    RETAIL STORES (PERSONAL SERVICES)
    40,180 SF Lot: 1.56 Acres
    Value Estimation by Request

    1404 Brg St, Chillicothe, OH 45601-4101

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    13110 State Rte 772
    RETAIL STORES (PERSONAL SERVICES)
    960 SF Lot: 0.40 Acres
    Value Estimation by Request

    13110 State Rte 772, Chillicothe, OH 45601-9293

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    465 Western Ave
    RETAIL STORES (PERSONAL SERVICES)
    5,580 SF Lot: 0.51 Acres
    Value Estimation by Request

    465 Western Ave, Chillicothe, OH 45601-2243

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    761 Main St
    RETAIL STORES (PERSONAL SERVICES)
    666 SF Lot: 0.10 Acres
    Value Estimation by Request

    761 Main St, Chillicothe, OH 45601-3506

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    State Rte 50
    RETAIL STORES (PERSONAL SERVICES)
    10,032 SF Lot: 1.01 Acres
    Value Estimation by Request

    State Rte 50, Chillicothe, OH 45601

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    711 High St
    RETAIL STORES (PERSONAL SERVICES)
    2,508 SF Lot: 0.12 Acres
    Value Estimation by Request

    711 High St, Chillicothe, OH 45601-1441

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    11437 County Rd 550
    RETAIL STORES (PERSONAL SERVICES)
    1,536 SF Lot: 1.50 Acres
    Value Estimation by Request

    11437 County Rd 550, Chillicothe, OH 45601-9787

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    46 Mulberry St
    RETAIL STORES (PERSONAL SERVICES)
    1,464 SF Lot: 0.04 Acres
    Value Estimation by Request

    46 Mulberry St, Chillicothe, OH 45601-2511

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    21 2nd St
    RETAIL STORES (PERSONAL SERVICES)
    1,650 SF Lot: 0.14 Acres
    Value Estimation by Request

    21 2nd St, Chillicothe, OH 45601-2524

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    86 Walnut St
    RETAIL STORES (PERSONAL SERVICES)
    2,440 SF Lot: 0.14 Acres
    Value Estimation by Request

    86 Walnut St, Chillicothe, OH 45601-2420

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    760 Brg St
    RETAIL STORES (PERSONAL SERVICES)
    3,936 SF Lot: 0.92 Acres
    Estimated value
    $815,000

    760 Brg St, Chillicothe, OH 45601-2672

    View details
    132 Main St
    RETAIL STORES (PERSONAL SERVICES)
    2,568 SF Lot: 0.07 Acres
    Value Estimation by Request

    132 Main St, Chillicothe, OH 45601-2508

    View details
    12 Water St
    RETAIL STORES (PERSONAL SERVICES)
    1,935 SF Lot: 0.04 Acres
    Value Estimation by Request

    12 Water St, Chillicothe, OH 45601-2421

    View details

    Chillicothe, OH Retail Space Investment Opportunities Market Analysis

    Explore 72 retail space for sale in Chillicothe, OH, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 9,232 square feet of properties for sale, with an estimated market value of $1,079,800.

    Sale prices for retail space in Chillicothe, OH start at $214,900, averaging $359,933, and reaching up to $650,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Shopping centers 4
    Storefront properties 3
    Auto shops 1
    Automotive properties 1

    Property Size Breakdown

    The majority of commercial real estate listings in Chillicothe fall within the 100,000+ square foot range.

    Demographics Overview

    Population 56K
    Population Growth (5Y) -0.5%
    Median Household Income $57,430
    College Educated 24.4%

    High-Yield Neighborhoods for Investment

    Identify Chillicothe submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    45601 $216.2K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

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    Most Searched ZIP Codes in Chillicothe, OH

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