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    Chillicothe, OH Mixed-use Properties for Sale

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    Kingston, OH Ray, OH Adelphi, OH
    Mixed-Use Asset in Chillicothe, OH
    $239,000
    2,800 SF

    Mixed-Use Asset in Chillicothe, OH

    83-85 Main Street, Chillicothe, OH 45601

    Versatile mixed-use property with income potential and repositioning opportunities.

    • Strong income potential with immediate cash flow from four existing tenants.
    • Flexible mixed‑use property (2,800 SF) suitable for retail, office, service, or residential use.
    • Spacious second‑floor residential unit ideal for owner‑occupancy or rental income.
    • Ample on‑site parking with 15+ spaces.
    • Value‑add upside through reconfiguration of the first floor.
    Updated: Apr 20
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    Downtown Chillicothe Mixed-Use Building
    $214,900
    2,200 SF

    Downtown Chillicothe Mixed-Use Building

    13 W 2ND ST, Chillicothe, OH 45602

    Versatile building in historic downtown Chillicothe with retail and residential/office potential.

    • Prime downtown Chillicothe location on the historic Union Block.
    • High‑visibility retail space on the main level for steady foot traffic.
    • Mixed‑use potential: retail space plus apartment or office space upstairs.
    • Opportunity to generate additional income from upstairs space.
    • Charming historic details.
    Updated: Sep 3, 2025
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    Renovated Mixed-Use Building For Sale
    $650,000
    4,832 SF

    Renovated Mixed-Use Building For Sale

    Renovated mixed-use building with high visibility and ample parking.

    7 Saint Andrews Blvd, Chillicothe, OH 45601
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    Downtown Chillicothe Mixed-Use Investment
    $214,900
    2,200 SF

    Downtown Chillicothe Mixed-Use Investment

    Versatile building in historic Union Block with retail and residential potential.

    11 W 2ND ST, Chillicothe, OH 45601
    View details
    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 4 Active listings in Chillicothe, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 3 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mixed-Use Building in Circleville, OH
    $424,900
    0.17 Acres

    Mixed-Use Building in Circleville, OH

    Two-story building with apartments and commercial space for sale.

    1002 S Court Street, Circleville, OH 43113
    View details
    Lancaster Mixed-Use Investment Opportunity
    $575,000
    4,960 SF

    Lancaster Mixed-Use Investment Opportunity

    Turnkey mixed-use building with bar and renovated apartments.

    530-532 N Columbus Street, Lancaster, OH 43130
    View details
    High-Visibility Commercial Building on Highway
    $550,000
    2,183 SF

    High-Visibility Commercial Building on Highway

    2,183 sq ft commercial building on 1.2-acre lot.

    24955 US Highway 23 S, Circleville, OH 43113
    View details
    Iconic Lancaster Mixed-Use Building
    $549,222
    6,538 SF

    Iconic Lancaster Mixed-Use Building

    Historic building with office and residential spaces in Lancaster.

    355 E Main Street, Lancaster, OH 43130
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Corner Lot in Ohio
    $225,000
    1.03 Acres

    Prime Corner Lot in Ohio

    One-acre corner lot suitable for commercial development in Canal Winchester.

    Chesterville Drive, Canal Winchester, OH 43110
    View details
    Development Land in Jeffersonville, Ohio
    $4,426,629
    88.71 Acres

    Development Land in Jeffersonville, Ohio

    88.71 acres of land suitable for development.

    12838 State Route 41, Jeffersonville, OH 43128
    View details
    Reynoldsburg Land Development Opportunity
    $529,000
    1.93 Acres

    Reynoldsburg Land Development Opportunity

    Mixed-use land suitable for multifamily and commercial development in Reynoldsburg.

    Tussing Road, Reynoldsburg, OH 43068
    View details
    Pickerington Land with Ponds
    $5,400,000
    60.63 Acres

    Pickerington Land with Ponds

    60+ acre land with woods, farmland, and ponds.

    6725 Blacklick-Eastern Road NW, Pickerington, OH 43147
    View details

    Off-Market Properties in Chillicothe, OH

    Consider similar Off-Market properties in Chillicothe, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    37-39 Paint St St

    37-39 Paint St St

    Mixed-use properties
    Value Estimation by Request
    37-39 Paint St St, Chillicothe, OH 45601
    View details
    1075 Western Ave Ave

    1075 Western Ave Ave

    Mixed-use properties • 2,487 SF
    Value Estimation by Request
    1075 Western Ave Ave, Chillicothe, OH 45601
    View details
    Chillicothe, OH 45601

    Chillicothe, OH 45601

    Land • 15.90 Acres
    Value Estimation by Request
    Chillicothe, OH 45601
    View details

    Chillicothe, OH Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 7 mixed-use properties for sale in Chillicothe, OH, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 12,032 square feet of properties for sale, with an estimated market value of $1,318,800.

    Sale prices for multi use buildings in Chillicothe, OH start at $214,900, averaging $329,700, and reaching up to $650,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

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    Property Size Breakdown

    The majority of commercial real estate listings in Chillicothe fall within the 100,000+ square foot range.

    Demographics Overview

    Population 56K
    Population Growth (5Y) -0.5%
    Median Household Income $57,430
    College Educated 24.4%

    High-Yield Neighborhoods for Strategic Investment

    Identify Chillicothe submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    45601 $368K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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