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Chillicothe, OH

Mixed-Use

Chillicothe, OH Mixed-use Properties for Sale

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Mount Vernon, OH Kingston, OH South Salem, OH

Downtown Chillicothe Mixed-Use Building

Updated: Sep 3, 2025

Downtown Chillicothe Mixed-Use Building

13 W 2ND ST, Chillicothe, OH 45602

$214,900

2,200 sqft

Prime downtown Chillicothe location on the historic Union Block.
High‑visibility retail space on the main level for steady foot traffic.
Mixed‑use potential: retail space plus apartment or office space upstairs.
Opportunity to generate additional income from upstairs space.
Charming historic details.

This listing looks promising.

Here's a quick look at some key insights for

13 W 2ND ST, Chillicothe, OH 45602

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Est. Cap Rate

7.6%
Above avg (5.9%)
Est. NOI

$16K
Annual
Price @ 7% Cap

$233K
Above asking
Last Sold

Jan 2023
$400K
Property Type

Retail Stores
Built 1942

View Property Analytics

Renovated Mixed-Use Building For Sale

Updated: Jan 27

Renovated Mixed-Use Building For Sale

7 Saint Andrews Blvd, Chillicothe, OH 45601

$650,000

4,832 sqft

High traffic count of 20,000 vehicles per day and strong visibility due to its LOCATION ON HISTORIC US ROUTE 50.
4,832 SF FULLY RENOVATED mixed‑use building suitable for commercial or residential re‑development.
Zoned commercial, offering significant potential for various business ventures.
Prime retail location adjacent to the Chillicothe Country Club and near established businesses like Chipotle and Bob Evans.
Ample paved parking lot for customers and employees.

Downtown Chillicothe Mixed-Use Investment

Downtown Chillicothe Mixed-Use Investment

11 W 2ND ST, Chillicothe, OH 45601

$214,900

2,200 sqft

Versatile building in historic Union Block with retail and residential potential.

Mixed-Use Corner Retail and Apartment

Mixed-Use Corner Retail and Apartment

275 N High St, Chillicothe, OH 45601

$450,000

2,600 sqft

Renovated street-level retail space with multiple entrances and an upper two-bedroom apartment, plus rear parking access.

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 4 Active listings in Chillicothe, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 3 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Versatile Commercial Property in Portsmouth

Versatile Commercial Property in Portsmouth

826 Gay St., Portsmouth, OH 45662

$264,500

2,208 sqft · 0.14 AC lot

High-visibility commercial property with versatile layout and living space.

Portsmouth Mixed-Use Commercial Property

Portsmouth Mixed-Use Commercial Property

2629 Scioto Trail, Portsmouth, OH 45662

$499,000

1,432 sqft · 1.07 AC lot

Commercial property with office space and apartments in Portsmouth, OH.

Versatile Commercial Space in Columbus

Versatile Commercial Space in Columbus

1115 Lawrence Drive, Columbus, OH 43207

$325,000

2,200 sqft

Move-in ready 2,200 SF commercial space with high visibility.

Retail Space on Parsons Avenue

Retail Space on Parsons Avenue

1351 Parsons Ave, Columbus, OH 43206

$1,250,000

9,660 sqft

Retail space for sale or lease with ample parking.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Versatile Land Parcel For Sale

Versatile Land Parcel For Sale

13223 Pleasant Valley Road, Chillicothe, OH 45601

$1,250,000

2,652,804 sqft · 61.40 AC lot

61.39 acres with commercial, agricultural, and subdivision potential.

Commercial Land Development Opportunity

Commercial Land Development Opportunity

2139-2121 Sonora Drive, Grove City, OH 43123

$890,000

84,942 sqft · 1.95 AC lot

1.95 acres of C-2 zoned land in Grove City.

Development Land in Jeffersonville, Ohio

Development Land in Jeffersonville, Ohio

12838 State Route 41, Jeffersonville, OH 43128

$4,426,629

88.71 AC lot

88.71 acres of land suitable for development.

High-Traffic Corner Location Land

High-Traffic Corner Location Land

4375 Refugee Road, Columbus, OH 43232

$3,900,000

1,092 sqft · 2.00 AC lot

Land with high visibility and new zoning for multiple uses.

Off-Market Properties in Chillicothe, OH

Consider similar Off-Market properties in Chillicothe, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

37-39 Paint St St

Mixed-use properties

37-39 Paint St St, Chillicothe, OH 45601

Value Estimation by Request

1075 Western Ave Ave

Mixed-use properties

1075 Western Ave Ave, Chillicothe, OH 45601

Value Estimation by Request

2,487 sqft

Chillicothe, OH 45601

Land

Chillicothe, OH 45601

Value Estimation by Request

15.90 AC lot

Chillicothe, OH Mixed-Use Properties Market Trends and Statistics

Explore 7 mixed-use properties for sale in Chillicothe, OH, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 11,832 square feet of properties for sale, with an estimated market value of $1,529,800.

Sale prices for multi use buildings in Chillicothe, OH start at $214,900, averaging $382,450, and reaching up to $650,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 56K

Population Growth (5Y) -0.5%

Median Household Income $57,430

College Educated 24.4%

High-Yield Neighborhoods for Investment

Identify Chillicothe submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
45601	$432.5K

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Ross County

New Delisted

Property Size Breakdown

The majority of commercial real estate listings in Chillicothe fall within the 100,000+ square foot range.

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