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    Chillicothe, OH Office Properties & Spaces for Sale

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    Cleveland, OH Columbus, OH Cincinnati, OH
    Mixed-Use Asset in Chillicothe, OH
    $239,000

    Mixed-Use Asset in Chillicothe, OH

    83-85 Main Street, Chillicothe, OH 45601

    Versatile mixed-use property with income potential and repositioning opportunities.

    • Strong income potential with immediate cash flow from four existing tenants.
    • Flexible mixed‑use property (2,800 SF) suitable for retail, office, service, or residential use.
    • Spacious second‑floor residential unit ideal for owner‑occupancy or rental income.
    • Ample on‑site parking with 15+ spaces.
    • Value‑add upside through reconfiguration of the first floor.
    Updated: Mar 31
    View details
    High-Traffic Commercial Property in Chillicothe
    $169,900
    1,496 SF

    High-Traffic Commercial Property in Chillicothe

    945 E Main Street, Chillicothe, OH 45601

    Versatile commercial building on East Main Street with high visibility.

    • High‑traffic location on East Main Street in Chillicothe.
    • Versatile building suitable for office, retail, or studio.
    • Large glass storefront providing excellent natural light and signage exposure.
    • Numerous off‑street parking spaces.
    • Large, open‑concept layout offering a blank canvas for customization.
    Updated: Apr 7
    View details
    Based on your search, we've compiled 238 Potential Opportunities for your consideration. Besides 2 Active listings in Chillicothe, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 228 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Lancaster East Side Office Building
    $475,000
    3,445 SF

    Lancaster East Side Office Building

    Former medical office with remodeled interior and upstairs apartment.

    435 E Main Street, Lancaster, OH 43130
    View details
    High-Visibility Commercial Building on Highway
    $550,000
    2,183 SF

    High-Visibility Commercial Building on Highway

    2,183 sq ft commercial building on 1.2-acre lot.

    24955 US Highway 23 S, Circleville, OH 43113
    View details
    Iconic Lancaster Mixed-Use Building
    $549,222
    6,538 SF

    Iconic Lancaster Mixed-Use Building

    Historic building with office and residential spaces in Lancaster.

    355 E Main Street, Lancaster, OH 43130
    View details
    Renovated Flex-Warehouse on 1.5 Acres
    Contact for pricing
    3,200 SF

    Renovated Flex-Warehouse on 1.5 Acres

    Newly renovated 3,200 SF flex-warehouse on 1.5 acres.

    22840 Canal Road, Circleville, OH 43113
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Land in Jackson
    $1,000,000
    22.00 Acres

    Prime Development Land in Jackson

    22 acres of high-traffic land near Walmart.

    0 Main and Ballard Street, Jackson, OH 45640
    View details
    Riverfront Commercial Land Opportunity
    $319,000
    7.43 Acres

    Riverfront Commercial Land Opportunity

    7.43 acre commercial land parcel along the Hocking River.

    Chieftain Drive, Logan, OH 43138
    View details
    Prime Corner Lot in Ohio
    $225,000
    1.03 Acres

    Prime Corner Lot in Ohio

    One-acre corner lot suitable for commercial development in Canal Winchester.

    Chesterville Drive, Canal Winchester, OH 43110
    View details
    Prime Commercial Land on I-270
    $799,900
    4.32 Acres

    Prime Commercial Land on I-270

    Vacant commercial lots with high visibility and frontage on I-270.

    1800 Georgesville Square Drive, Columbus, OH 43228
    View details

    Explore Off-Market Properties in Chillicothe, OH

    Consider similar Off-Market properties in Chillicothe, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    90 Main St

    90 Main St

    OFFICE BUILDING • 416 SF
    Value Estimation by Request
    90 Main St, Chillicothe, OH 45601-3103
    View details
    10 Dun Rd

    10 Dun Rd

    MEDICAL BUILDING • 2,182 SF
    Value Estimation by Request
    10 Dun Rd, Chillicothe, OH 45601-1101
    View details
    20-22 2nd St

    20-22 2nd St

    OFFICE BUILDING • 1,100 SF
    Value Estimation by Request
    20-22 2nd St, Chillicothe, OH 45601
    View details
    23 Paint St

    23 Paint St

    PROFESSIONAL BUILDING (MULTI-STORY) • 738 SF
    Value Estimation by Request
    23 Paint St, Chillicothe, OH 45601-3211
    View details
    19 Paint St

    19 Paint St

    OFFICE BUILDING • 990 SF
    Value Estimation by Request
    19 Paint St, Chillicothe, OH 45601-3116
    View details
    36 Walnut St

    36 Walnut St

    MEDICAL BUILDING • 3,453 SF
    Value Estimation by Request
    36 Walnut St, Chillicothe, OH 45601-3114
    View details
    154 Brg St

    154 Brg St

    MEDICAL BUILDING • 391 SF
    Value Estimation by Request
    154 Brg St, Chillicothe, OH 45601
    View details
    72 Paint St

    72 Paint St

    OFFICE BUILDING • 4,860 SF
    Value Estimation by Request
    72 Paint St, Chillicothe, OH 45601-2418
    View details
    77 Main St

    77 Main St

    MEDICAL BUILDING • 828 SF
    Value Estimation by Request
    77 Main St, Chillicothe, OH 45601-3104
    View details
    60 Riverside St

    60 Riverside St

    PROFESSIONAL BUILDING (MULTI-STORY) • 5,500 SF
    Value Estimation
    $530,000
    60 Riverside St, Chillicothe, OH 45601-2584
    View details
    192 Paint St

    192 Paint St

    MEDICAL BUILDING • 1,584 SF
    Value Estimation by Request
    192 Paint St, Chillicothe, OH 45601-3827
    View details
    377 Gtwy Dr

    377 Gtwy Dr

    PROFESSIONAL BUILDING (MULTI-STORY) • 2,400 SF
    Value Estimation
    $1,790,000
    377 Gtwy Dr, Chillicothe, OH 45601-3976
    View details
    126 4th St

    126 4th St

    OFFICE BUILDING • 1,600 SF
    Value Estimation by Request
    126 4th St, Chillicothe, OH 45601-3363
    View details
    78 Mulberry St

    78 Mulberry St

    OFFICE BUILDING • 720 SF
    Value Estimation by Request
    78 Mulberry St, Chillicothe, OH 45601-3321
    View details
    3 Medical Dr

    3 Medical Dr

    PROFESSIONAL BUILDING (MULTI-STORY) • 2,682 SF
    Value Estimation
    $550,000
    3 Medical Dr, Chillicothe, OH 45601-8603
    View details
    20700 Us Hwy 23

    20700 Us Hwy 23

    OFFICE BUILDING • 12,000 SF
    Value Estimation
    $2,270,000
    20700 Us Hwy 23, Chillicothe, OH 45601-9016
    View details
    20700 Us Hwy 23

    20700 Us Hwy 23

    PROFESSIONAL BUILDING (MULTI-STORY) • 3,360 SF
    Value Estimation
    $2,270,000
    20700 Us Hwy 23, Chillicothe, OH 45601-9016
    View details
    2179 Anderson Sta Rd

    2179 Anderson Sta Rd

    PROFESSIONAL BUILDING (MULTI-STORY) • 1,432 SF
    Value Estimation
    $3,470,000
    2179 Anderson Sta Rd, Chillicothe, OH 45601-8856
    View details
    72 2nd St

    72 2nd St

    OFFICE BUILDING • 540 SF
    Value Estimation by Request
    72 2nd St, Chillicothe, OH 45601-3110
    View details
    Cor Walnut

    Cor Walnut

    OFFICE BUILDING • 2,715 SF
    Value Estimation by Request
    Cor Walnut, Chillicothe, OH 45601
    View details
    106 Walnut St

    106 Walnut St

    OFFICE BUILDING • 976 SF
    Value Estimation by Request
    106 Walnut St, Chillicothe, OH 45601-3220
    View details
    94 2nd St

    94 2nd St

    OFFICE BUILDING • 1,352 SF
    Value Estimation by Request
    94 2nd St, Chillicothe, OH 45601-2523
    View details

    Chillicothe, OH Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 230 office properties & spaces for sale in Chillicothe, OH on our real estate platform. These investment opportunities span a total of 20,530,786 square feet of properties for sale, with an estimated market value of $56,300,000.

    Sale prices for office spaces in Chillicothe, OH start at $60,000, averaging $325,433, and reaching up to $3,470,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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