Medical Space

Chillicothe, OH Medical Office Space for Lease

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Circleville, OH Piketon, OH
Ambulatory Surgical Center and Medical Offices
Updated: Jun 17
Ambulatory Surgical Center and Medical Offices

1050 River Road, Chillicothe, OH 45601

$29 SF/Yr
Full‑service ambulatory surgical center with 4 ORs and 2 procedure rooms
Across the street from Adena Hospital
Retail visibility on SR 23 with access to patients in Central, South, and Southeast Ohio
Medical office space offered with options to lease or own
Delivery expected in early to mid‑2026
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1 active listing matches your search: Medical Office for lease in Chillicothe, OH. Based on your search, we've also compiled 4 Potential Opportunities for your consideration: 4 spaces in nearby cities.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Office Unit
Office Unit

1015 S Court Street A, Circleville, OH 43113

$1,500/Mo
54–90 people  13,528 sqft  Built 1978

Approximately 1,400 square feet offers a flexible commercial setting for office, retail, or professional use.

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Medical Office Space with Flexible Size
Medical Office Space with Flexible Size

2950 London Groveport Rd, Grove City, OH 43123

Triple net (NNN)
Contact for pricing
2,500–10,500 sqft  Built 2027

Available configurations accommodate medical, office, and select retail uses.

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Flexible Office Suites
Flexible Office Suites

617 Brookhill Lane #300, Circleville, OH 43113

$300/Mo
28–47 people  7,158 sqft  Built 1981

Spaces range from individual offices to larger suites suited to a medical practice, physician’s office, or spa.

Shared kitchen  Conference room  Internet
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Medical Office Space Near Highways
Medical Office Space Near Highways

4207 Gantz Road, Grove City, OH 43123

$16.95 SF/Yr

Built in 2018 with on-site parking and convenient connections to I-71 and I-270.

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Chillicothe, OH Medical Office Space Lease Rates & Market Statistics

Explore 1 Medical Office Space listing for lease in Chillicothe, OH on Realmo, a commercial real estate exchange covering the Chillicothe area.

Asking lease rates for Medical Office Space in Chillicothe start at $29 SF/Yr, average $29 SF/Yr, and reach $29 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $29 SF/Yr, the local average runs 78% above Ohio's state average of $16.27 SF/Yr.

Chillicothe accounts for 100% of the 1 medical office space listing currently available across Ross County. Medical Office Space is one of the more limited space types in Chillicothe, with just 1 listing currently available — a scarcity worth factoring into lease negotiations.

How to lease medical office space in Chillicothe, OH

  1. Map your clinical requirements. List exam rooms, lab or imaging areas, and infrastructure needs. Medical suites demand upgraded plumbing, HVAC, and electrical capacity that ordinary offices lack.
  2. Choose a patient-friendly location. Use Location Intelligence to find Chillicothe, OH areas with strong demand for healthcare, target patient demographics, and check proximity to hospitals and referring physicians.
  3. Verify compliance and parking. Confirm that the space can meet ADA and HIPAA requirements and offers roughly 4.5 parking spaces per 1,000 sq. ft. to handle steady patient flow.
  4. Hire a medical-specialist tenant broker. Healthcare leasing is a niche, so a specialized broker flags zoning, code, and biomedical waste issues that general brokers miss, at no cost to you.
  5. Model the long-term cost. Medical build-outs run $150–250 per sq. ft., pushing leases to 7–10 years. Project the full occupancy cost with the Lease Calculator before committing.
  6. Negotiate healthcare-specific clauses. Secure a strong TI allowance, an exclusivity clause blocking competing practices in the building, a broad use clause, and after-hours access before your attorney signs off.
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