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    Chillicothe, OH
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    Chillicothe, OH Retail Properties & Spaces for Sale

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    Kingston, OH Londonderry, OH South Salem, OH
    12 results
    High-Traffic Commercial Property on Main
    $159,900
    1,496 SF
    High-Traffic Commercial Property on Main

    945 E Main Street, Chillicothe, OH 45601

    Versatile commercial building in Chillicothe with high visibility.
    • High‑traffic location on East Main Street in Chillicothe.
    • Versatile building suitable for office, retail, or studio.
    • Large glass storefront providing excellent natural light and signage exposure.
    • Numerous off‑street parking spaces.
    • Large, open‑concept layout offering a blank canvas for customization.
    Updated: May 12
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    Main Street Investment Opportunity
    $550,000
    5,244 SF
    Main Street Investment Opportunity

    946-954 E Main Street, Chillicothe, OH 45601

    High-visibility commercial building with established tenants in a prime location.
    • Prime Main Street location with excellent exposure.
    • Immediate income from three established tenants.
    • Strong investment potential in a thriving business district.
    • 5,200+ sq ft commercial building.
    • Solid rental history.
    Updated: Sep 3, 2025
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    Downtown Chillicothe Mixed-Use Building
    $214,900
    2,200 SF
    Downtown Chillicothe Mixed-Use Building

    Versatile building in historic downtown Chillicothe with retail and residential/office potential.

    13 W 2ND ST, Chillicothe, OH 45602

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    Renovated Mixed-Use Building For Sale
    $650,000
    4,832 SF
    Renovated Mixed-Use Building For Sale

    Renovated mixed-use building with high visibility and ample parking.

    7 Saint Andrews Blvd, Chillicothe, OH 45601

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    Downtown Chillicothe Mixed-Use Investment
    $214,900
    2,200 SF
    Downtown Chillicothe Mixed-Use Investment

    Versatile building in historic Union Block with retail and residential potential.

    11 W 2ND ST, Chillicothe, OH 45601

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    Prime Retail Ground Lease Opportunity
    Contact for pricing
    1.35 Acres
    Prime Retail Ground Lease Opportunity

    1.35 acre commercial land in high-traffic retail corridor.

    1487 Bridge Street, Chillicothe, OH 45601

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    Established Tire Business For Sale
    $369,000
    2,020 SF
    Established Tire Business For Sale

    Well-respected tire business on a highly visible corner lot.

    394 N High St, Chillicothe, OH 45601

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    Retail Space on Bridge Street
    Contact for pricing
    Retail Space on Bridge Street

    NNN lease opportunity in Chillicothe, with high visibility.

    27 Bridge Street, Chillicothe, OH 45601

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    Prime Retail Site on Western
    $439,000
    0.71 Acres
    Prime Retail Site on Western

    0.71-acre retail site with high traffic and visibility.

    1318 Western Ave, Chillicothe, OH 45601

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    New Chipotle with Drive-Thru
    $2,552,631
    2,325 SF
    New Chipotle with Drive-Thru

    New Chipotle with drive-thru in growing Ross County.

    6 St Andrews Blvd, Chillicothe, OH

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    Renovated Commercial Property on Western
    $300,000
    1,848 SF
    Renovated Commercial Property on Western

    Renovated commercial property on busy Western Ave in Chillicothe.

    2111 Western Avenue, Chillicothe, OH 45601

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    Two-Tenant Retail Building For Sale
    $5,801,000
    72,010 SF
    Two-Tenant Retail Building For Sale

    Two-tenant retail building with long-term leases in Chillicothe, Ohio.

    1470 N Bridge St, Chillicothe, OH

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 12 Active listings in Chillicothe, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 60 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Commercial Space on Corner Lot
    $240,000
    8,752 SF
    Versatile Commercial Space on Corner Lot

    8752 sq ft commercial space on busy corner lot.

    2758 State Route 41, Bainbridge, OH 45612

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    Mixed-Use Building in Circleville, OH
    $424,900
    0.17 Acres
    Mixed-Use Building in Circleville, OH

    Two-story building with apartments and commercial space for sale.

    1002 S Court Street, Circleville, OH 43113

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    High-Visibility Commercial Building on Highway
    $550,000
    2,183 SF
    High-Visibility Commercial Building on Highway

    2,183 sq ft commercial building on 1.2-acre lot.

    24955 US Highway 23 S, Circleville, OH 43113

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    Versatile Commercial Space on State Route
    $250,000
    8,752 SF
    Versatile Commercial Space on State Route

    Corner lot commercial building suitable for warehouse, retail, or office.

    2758 State Route 41 S, Bainbridge, OH 45612

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Corner Lot on SR 23
    $650,000
    0.86 Acres
    Commercial Corner Lot on SR 23

    Prime commercial land in a high-traffic area, ready to build.

    5050 S Walnut Street, South Bloomfield, OH 43103

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    Highway Commercial Land Available
    $7,000,000
    2,024 SF
    Highway Commercial Land Available

    25 acres of highway commercial land in South Bloomfield, Ohio.

    14337 Highway 23, Ashville, OH 43103

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    South Bloomfield Acreage on US-23
    $15,328,800
    16,109,359 SF
    South Bloomfield Acreage on US-23

    394.84 acres in South Bloomfield near Columbus, OH.

    14337 Highway 23, Ashville, OH 43103

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    Land For Sale
    $4,000,000
    Land For Sale

    Land available in Hocking County.

    11973 Dalton Road, Rockbridge, OH 43149

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    Off-Market Properties in Chillicothe, OH

    Consider similar Off-Market properties in Chillicothe, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    19 2nd St
    RETAIL STORES (PERSONAL SERVICES)
    1,000 SF Lot: 0.03 Acres
    Value Estimation by Request

    19 2nd St, Chillicothe, OH 45601-3111

    View details
    19 2nd St
    RETAIL STORES (PERSONAL SERVICES)
    2,400 SF Lot: 0.01 Acres
    Value Estimation by Request

    19 2nd St, Chillicothe, OH 45601-2524

    View details
    1050 Main St
    RETAIL STORES (PERSONAL SERVICES)
    9,100 SF Lot: 1.08 Acres
    Estimated value
    $1,540,000

    1050 Main St, Chillicothe, OH 45601-2848

    View details
    20 Main St
    RETAIL STORES (PERSONAL SERVICES)
    1,482 SF Lot: 0.06 Acres
    Value Estimation by Request

    20 Main St, Chillicothe, OH 45601-2503

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    10 Riv Trce
    RESTAURANT
    5,521 SF Lot: 2.15 Acres
    Estimated value
    $1,255,000

    10 Riv Trce, Chillicothe, OH 45601-2686

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    375 Marietta Rd
    RETAIL STORES (PERSONAL SERVICES)
    1,704 SF Lot: 0.70 Acres

    375 Marietta Rd, Chillicothe, OH 45601-9433

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    31 Paint St
    RETAIL STORES (PERSONAL SERVICES)
    1,136 SF Lot: 0.08 Acres
    Value Estimation by Request

    31 Paint St, Chillicothe, OH 45601-3211

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    118 2nd St Rear
    PARKING GARAGE, PARKING STRUCTURE
    520 SF Lot: 0.15 Acres
    Value Estimation by Request

    118 2nd St Rear, Chillicothe, OH 45601-3112

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    1492 Brg St
    CAR WASH
    5,685 SF Lot: 1.50 Acres
    Value Estimation by Request

    1492 Brg St, Chillicothe, OH 45601-4101

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    800 Western Ave
    DRIVE-THRU RESTAURANT, FAST FOOD
    2,800 SF Lot: 0.98 Acres
    Value Estimation by Request

    800 Western Ave, Chillicothe, OH 45601-2138

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    1404 Brg St
    RETAIL STORES (PERSONAL SERVICES)
    40,180 SF Lot: 1.56 Acres
    Value Estimation by Request

    1404 Brg St, Chillicothe, OH 45601-4101

    View details
    242 Park St
    AUTO REPAIR, GARAGE
    3,200 SF Lot: 0.12 Acres
    Value Estimation by Request

    242 Park St, Chillicothe, OH 45601-1618

    View details

    Chillicothe, OH Retail Properties & Spaces Investment Opportunities Market Analysis

    Explore 72 retail properties & spaces for sale in Chillicothe, OH, showcased through 12 active listings on our real estate platform. These investment opportunities span a total of 96,975 square feet of properties for sale, with an estimated market value of $11,051,331.

    Sale prices for stores in Chillicothe, OH start at $159,900, averaging $1,105,133, and reaching up to $5,801,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Map

    Top Commercial Asset Segments

    Shopping centers 4
    Storefront properties 3
    Auto shops 1
    Automotive properties 1

    Property Size Breakdown

    The majority of commercial real estate listings in Chillicothe fall within the 100,000+ square foot range.

    Demographics Overview

    Population 56K
    Population Growth (5Y) -0.5%
    Median Household Income $57,430
    College Educated 24.4%

    High-Yield Neighborhoods for Investment

    Identify Chillicothe submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    45601 $298.1K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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