San Diego County, CA Commercial Real Estate for Sale

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Updated: Mar 11

Three-Story Mixed-Use Building

2368 2nd AVE, San Diego, CA 92101

$2,669,000

3,800 sqft 0.13 AC lot

3‑story mixed‑use building with approximately 3,800 square feet
0.1251‑acre parcel at 2368 2nd AVE, San Diego, CA 92101
Independent access to each floor supports separate occupancy or leasing
Mixed‑use zoning accommodates commercial and residential configurations
Mills Act property with tax benefits for qualified owners

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Updated: Feb 5

Three-Unit Storefront Building

1025-29 E Valley Pkwy, Escondido, CA 92025

$1,500,000

2,400 sqft

Three approximately 800 SF units within a single‑story commercial building
Approximately 2,400 SF building on a 7,668 SF lot
Independent front and rear access for each unit
C‑6 (Commercial) zoning designation
Located at 1025‑29 E Valley Pkwy in Escondido

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Two-Unit Office Building

651-53 E. Valley Packway, Escondido, CA 92025

$725,000

0.07 AC lot

Separate office suites include parking behind the building and professional-use potential.

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See what stands out in San Diego County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

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6-Bay Auto Shop

729 D Street, Ramona, CA 92065

$1,250,000

4,000 sqft 0.25 AC lot

CMU and steel construction, multiple lifts, and secondary alley access support automotive service operations.

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26-Unit Apartment Building

4017 42nd St, San Diego, CA 92105

$8,995,000

9,112 sqft

Commercially zoned apartment property with private bathrooms and an existing NNN master lease.

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Upgraded Mixed-Use Property

110 Maple, San Diego, CA 92103

$4,890,000

3,750 sqft 0.13 AC lot

Five-unit corner asset combines professional office space with remodeled residential units and shared landscaped courtyard.

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Freestanding Drive-Through Restaurant

8213 Broadway, Lemon Grove, CA 91945

$1,100,000

0.16 AC lot

Established restaurant property with monument signage, dedicated parking, and commercial zoning.

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Fenced-Yard Flex Space

9220 Jamacha Road, Spring Valley, CA 91977

$2,200,000

3,600 sqft 0.30 AC lot

M54 zoning supports industrial use, with office and warehouse areas plus utility connections already in place.

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Mixed-Use Storefront Property

3275 Euclid, San Diego, CA 92105

$900,000

0.11 AC lot

Corner-lot commercial property with storefront space and separate entrances.

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Vineyard and Winery with Tasting Room

34680 Highway 79, Warner Springs, CA 92086

$2,200,000

5,000 sqft 40.00 AC lot

Vineyard property with wine production, hospitality, event, lodging, and residential improvements.

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Remodeled Restaurant with Mezzanine Storage

113 Grand Ave, Escondido, CA 92025

$1,800,000

3,400 sqft

Full-service kitchen, bar, storage, and rear alley access support restaurant operations.

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Mixed-Use Property with Rental Units

2560-66 Alpine Blvd, Alpine, CA 91901

$2,300,000

2.24 AC lot

Two legal lots combine residential rentals with a commercial storefront along Alpine Boulevard.

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Commercial Infill Land Parcel

47th St, San Diego, CA 92102

$500,000

0.14 AC lot

Vacant commercial-zoned parcel with existing curbs and access to surrounding neighborhoods, businesses, and major roadways.

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Freestanding Office Building

5050 Federal Boulevard, San Diego, CA 92102

$3,300,000

9,930 sqft 0.58 AC lot

Renovated commercial office property with flexible rooms, accessible facilities, gated parking, and an adjoining apartment.

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Corner Commercial Land

Jamacha Blvd, Spring Valley, CA 91977

$539,000

0.36 AC lot

Flat, tree-free land with R I AND Commercial zoning at Jamacha Blvd and Concepcion.

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Nursery Property with Greenhouses

3129 Reche Road, Fallbrook, CA 92028

$1,900,000

8.68 AC lot

Agricultural acreage with existing nursery improvements, shade structures, and electricity available.

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Freestanding Office Building

6334 University Ave, San Diego, CA 92115

$950,000

2,273 sqft

Functional office configuration with reception areas, private rooms, monument signage, rear access, and on-site parking.

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Remodeled Three-Unit Triplex

3050 K St, San Diego, CA 92102

$1,350,000

1,200 sqft

The property carries R-2:MINOR zoning and includes private entrances with alley access for two units.

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Medical Office Condominium Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

$2,113,852

88,872 sqft 3.05 AC lot

Well-maintained four-story medical office building with upgraded interiors and common areas, positioned for healthcare operators.

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Five-Suite Mixed-Use Property

2344 Highway 67, Ramona, CA 92065

$1,295,000

0.70 AC lot

The property has commercial zoning, on-site parking, and five suites.

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Two-Unit Storefront Building

121 123 W. GRAND AVE 2, Escondido, CA 92025

$769,000

1,600 sqft

Single-story commercial building with an art gallery and barber shop.

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Historic Cedar-Sided Mixed-Use Property

780 Main Street, Ramona, CA 92065

$2,300,000

Tenant-occupied commercial building with a varied business mix and private lighted parking in Old Town Ramona.

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Ground-Floor Office Condo Suite

3740 Park Boulevard Cu1, San Diego, CA 92103

$2,100,000

2,360 sqft

Modern ground-floor office condo built in 2007 with private offices, reception, open work areas, and multiple entrances.

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Live-Work Space with Two Offices

2487 Kettner Blvd, San Diego, CA 92101

$1,149,000

1,610 sqft 0.02 AC lot

Commercially zoned property with two kitchens, an upgraded full bath, and mixed-use flexibility for office or residential use.

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San Diego County, CA Commercial Real Estate Market Trends and Statistics

Explore 971 commercial real estate for sale in San Diego County, CA, showcased through 971 active listings on our real estate platform. These investment opportunities span a total of 10,350,731 square feet of properties for sale, with an estimated market value of $1,029,484,795.

Sale prices for business properties in San Diego County, CA start at $35,000, averaging $2,100,989, and reaching up to $23,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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