San Diego County, CA Commercial Real Estate for Sale

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Mixed-Use Property with Residence
Updated: Sep 25
Mixed-Use Property with Residence

2971 Imperial Avenue, San Diego, CA 92102

$1,080,000
1,775 sqft 0.13 AC lot
Remodeled detached residence with 3 bedrooms and 2.5 bathrooms
Separate commercial building faces Imperial Avenue
Approximately 5,600‑square‑foot lot zoned CN‑1‑3
Complete Communities Housing Solutions Tier 3 area; qualifying projects may offer up to 6.5 FAR
Covered patio and gated driveway with alley access
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Multifamily Property With Detached Units
Updated: Sep 10
Multifamily Property With Detached Units

4159 38th St, San Diego, CA 92105

$999,000
1,386 sqft 0.08 AC lot
Three detached living spaces on a 0.0804‑acre lot
1,386 square feet with 3 bedrooms, 1.5 bathrooms, and in‑unit laundry in the primary residence
Additional dwellings include 1 bedroom and 1 bathroom each
RM‑2‑5 zoning
Built in 1926 with a composition roof
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26-Unit Apartment Building
26-Unit Apartment Building

4017 42nd St, San Diego, CA 92105

$8,995,000
9,112 sqft

A master NNN lease with a nonprofit operator is in place.

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Office Building with Covered Patio
Office Building with Covered Patio

2419 El Cajon, San Diego, CA 92104

$2,500,000
5,000 sqft 0.16 AC lot

An existing architectural office pairs open work areas and a glass-walled conference room with outdoor space beneath a pergola.

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Three-Unit Storefront Building
Three-Unit Storefront Building

1025-29 E Valley Pkwy, Escondido, CA 92025

$1,500,000
2,400 sqft

Single-story commercial property with separately accessed spaces and C-6 zoning along E Valley Parkway.

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Office Building with Covered Patio
Office Building with Covered Patio

2419 El Cajon, San Diego, CA 92104

$2,500,000
0.16 AC lot

An open-plan interior pairs gallery and work areas with a glass conference room and sheltered outdoor space.

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Two-Unit Office Building
Two-Unit Office Building

651-53 E. Valley Packway, Escondido, CA 92025

$725,000
0.07 AC lot

Separate office suites include parking behind the building and professional-use potential.

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Auto Body Shop Building
Auto Body Shop Building

951 Broadway, Chula Vista, CA 91911

$2,500,000
6,750 sqft 0.59 AC lot

An existing automotive business occupies a substantial building with a separate lot.

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Freestanding Drive-Through Restaurant
Freestanding Drive-Through Restaurant

8213 Broadway, Lemon Grove, CA 91945

$1,100,000
0.16 AC lot

Established restaurant property with monument signage, dedicated parking, and commercial zoning.

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Mixed-Use Building with Retail Space
Mixed-Use Building with Retail Space

3580 Adams Ave, San Diego, CA 92116

$2,600,000
3,690 sqft 0.15 AC lot

Retail space and five apartments share the property, with alley access and on-site parking.

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6-Bay Auto Shop
6-Bay Auto Shop

729 D Street, Ramona, CA 92065

$1,250,000
4,000 sqft 0.25 AC lot

CMU and steel construction, multiple lifts, and secondary alley access support automotive service operations.

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Mixed-Use Storefront Property
Mixed-Use Storefront Property

3275 Euclid, San Diego, CA 92105

$900,000
0.11 AC lot

Corner-lot commercial property with storefront space and separate entrances.

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Upgraded Mixed-Use Property
Upgraded Mixed-Use Property

110 Maple, San Diego, CA 92103

$4,810,000
3,750 sqft 0.13 AC lot

Five-unit corner asset combines professional office space with remodeled residential units and shared landscaped courtyard.

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Penthouse Office Suite
Penthouse Office Suite

1350 Columbia St, San Diego, CA 92101

$3,875,000
6,678 sqft

The ninth-floor workspace includes collaborative seating, a glass-enclosed conference room, phone pods, and a hospitality bar.

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Corner Commercial Land
Corner Commercial Land

Jamacha Blvd, Spring Valley, CA 91977

$539,000
0.36 AC lot

Flat, tree-free land with R I AND Commercial zoning at Jamacha Blvd and Concepcion.

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Vineyard and Winery with Tasting Room
Vineyard and Winery with Tasting Room

34680 Highway 79, Warner Springs, CA 92086

$2,200,000
5,000 sqft 40.00 AC lot

Vineyard property with wine production, hospitality, event, lodging, and residential improvements.

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Circle K Ground-Leased NNN Property
Circle K Ground-Leased NNN Property

746 Main Street, Chula Vista, CA 91911

$4,444,000
4,625 sqft

A corporate Circle K lease assigns zero landlord responsibilities under an absolute NNN structure.

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Mixed-Use Property with Rental Units
Mixed-Use Property with Rental Units

2560-66 Alpine Blvd, Alpine, CA 91901

$2,300,000
2.24 AC lot

Two legal lots combine residential rentals with a commercial storefront along Alpine Boulevard.

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Mixed-Use Property with Residence
Mixed-Use Property with Residence

2971 Imperial Ave, San Diego, CA 92102

$1,080,000
700 sqft 0.13 AC lot

A detached home and separate Imperial Ave commercial building occupy a gated site with alley access.

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Equestrian Property with Water Wells
Equestrian Property with Water Wells

42355 Fresz Road, Aguanga, CA 92536

$725,000
29.43 AC lot

Two parcels include a manufactured home, horse facilities, and open acreage with lake, mountain, and valley views.

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Auto Repair Shop with Equipment
Auto Repair Shop with Equipment

301 16th St, San Diego, CA 92101

$1,492,000
1,926 sqft 0.10 AC lot

The existing automotive service setup includes repair equipment, three-phase power, and on-site parking.

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Remodeled 4-Unit Quadplex
Remodeled 4-Unit Quadplex

6979-85 Lisbon St, San Diego, CA 92114

$1,450,000
0.09 AC lot

All four residences are occupied and professionally managed, with remodeled interiors and central heating and air conditioning.

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Fenced-Yard Flex Space
Fenced-Yard Flex Space

9220 Jamacha Road, Spring Valley, CA 91977

$2,200,000
3,600 sqft 0.30 AC lot

M54 zoning supports industrial use, with office and warehouse areas plus utility connections already in place.

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Five-Suite Mixed-Use Property
Five-Suite Mixed-Use Property

2344 Highway 67, Ramona, CA 92065

$1,295,000
0.70 AC lot

The property has commercial zoning, on-site parking, and five suites.

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San Diego County, CA Commercial Real Estate Market Trends and Statistics

Explore 926 commercial real estate for sale in San Diego County, CA, showcased through 926 active listings on our real estate platform. These investment opportunities span a total of 27,182,689 square feet of properties for sale, with an estimated market value of $1,046,621,164.

Sale prices for business properties in San Diego County, CA start at $35,000, averaging $2,153,541, and reaching up to $42,220,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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