Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Seneca, SC Commercial Real Estate for Lease

    16 results
    List
    Map
    Seneca Office Space For Lease
    $1,500 / Mo
    26,136 SF

    Seneca Office Space For Lease

    865 Old Clemson Hwy, Seneca, SC 29678

    Two-level office building suitable for various businesses, near Clemson.

    • Suitable for various business types, including medical/dental offices.
    • Two levels with separate entrances and restrooms, offering flexible leasing options (entire building or individual floors).
    • Located in close proximity to Clemson and Seneca.
    • Lower level features 3 offices, conference room, and reception area (Lease: $1,750.00 NNN).
    • Upper level offers 5 offices and a reception area (Lease: $2,900.00 NNN).
    Updated: Feb 27
    View details
    Office Space Near Clemson
    $4,000 / Mo
    26,136 SF

    Office Space Near Clemson

    865 Old Clemson Hwy, Seneca, SC 29678

    Two-level office building suitable for various businesses, near Clemson.

    • Close proximity to Clemson and Seneca
    • Suitable for various business types and offices
    • Potential conversion to medical or dental office
    • Two levels with separate entrances
    • Multiple offices and restrooms on each level
    Updated: Feb 27
    View details
    Office Space in Seneca, SC
    $2,500 / Mo
    26,136 SF

    Office Space in Seneca, SC

    Commercial office space available for lease in Seneca, South Carolina.

    865 Old Clemson Hwy, Seneca, SC 29678
    View details
    Seneca Retail/Office Space Available
    $1,700 / Mo

    Seneca Retail/Office Space Available

    Retail/office space for lease in Seneca, SC. Renovated and visible.

    1109 Jennings Ave, Seneca, SC 29768
    View details
    Commercial Land on US Highway
    $72,000
    63,162 SF

    Commercial Land on US Highway

    1.45 acre commercial land for ground lease in Seneca, SC.

    994 Us 123 Hwy, Seneca, SC 29678
    View details
    Retail Space Near Clemson University
    $21 SF/Yr

    Retail Space Near Clemson University

    End-cap retail space with drive-thru potential near Clemson University.

    1085 Old Clemson Hwy, Seneca, SC 29672
    View details
    Retail Space Available For Lease
    $1,150 / Mo

    Retail Space Available For Lease

    Retail space available for lease on Clemson Boulevard, Seneca, SC.

    10139A Clemson Blvd, Seneca, SC 29678
    View details
    Retail Opportunity Near Walmart
    Contact for pricing

    Retail Opportunity Near Walmart

    Retail space available for lease, GL, or build-to-suit.

    1637 Sandifer Blvd, Seneca, SC 29678
    View details
    Retail Opportunity Near Walmart
    Contact for pricing

    Retail Opportunity Near Walmart

    Retail space available for lease near Walmart and hospital.

    1637 Sandifer Blvd, Seneca, SC 29678
    View details
    Retail Property on Main Corridor
    Contact for pricing
    7,250 SF

    Retail Property on Main Corridor

    Retail property with excellent visibility and heavy traffic.

    1592 Sandifer Blvd, Seneca, SC 29678
    View details
    Applewood Shopping Center Opportunity
    Contact for pricing
    244,693 SF

    Applewood Shopping Center Opportunity

    High-traffic retail center near Clemson University

    201 Applewood Center Pl, Seneca, SC 29678
    View details
    Seneca Office/Retail Space Available
    $15 SF/Yr
    4,800 SF

    Seneca Office/Retail Space Available

    Office and retail spaces for lease in Seneca, South Carolina.

    12019 North Radio Station Rd, Seneca, SC 29678
    View details
    Applewood Shopping Center: Seneca, SC
    $22 SF/Yr
    245,000 SF

    Applewood Shopping Center: Seneca, SC

    Prime Seneca Retail Space Available

    285 Applewood Center Pl, Seneca, SC 29678
    View details
    Restaurant Space Near Oconee Medical
    Contact for pricing
    16,000 SF

    Restaurant Space Near Oconee Medical

    1,600 SF 2nd Gen Restaurant Space Available For Rent.

    201-273 Applewood Center Pl, Seneca, SC 29678
    View details
    Land Near Oconee Medical Center
    Contact for pricing

    Land Near Oconee Medical Center

    Commercial land for rent near medical center and Clemson University.

    15516 Wells Hwy, Seneca, SC 29678
    View details
    Retail Space Near Oconee Medical
    Contact for pricing
    1,600 SF

    Retail Space Near Oconee Medical

    Retail space available near Oconee Medical Center and Clemson University.

    101 Applewood Center Pl, Seneca, SC 29678
    View details
    Based on your search, we've compiled 71 Potential Opportunities for your consideration. Besides 16 Active listings in Seneca, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 51 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail/Restaurant Space Near Clemson University
    Contact for pricing
    3,500 SF

    Retail/Restaurant Space Near Clemson University

    Retail/restaurant space with dedicated parking and lake access.

    894 Tiger Blvd, Clemson, SC 29631
    View details
    Downtown Clemson Retail Space Available
    $2,800 / Mo

    Downtown Clemson Retail Space Available

    Retail space in downtown Clemson, formerly a coffee shop.

    382 College Ave Unit, Clemson, SC 29631
    View details
    Move-in Ready Office Space
    $2,200 / Mo
    15,246 SF

    Move-in Ready Office Space

    Well-maintained office space in established professional park, ready for occupancy.

    111 N Earle St, Walhalla, SC 29691
    View details
    Remodeled Restaurant Space on Main
    $2,000 / Mo
    2,614 SF

    Remodeled Restaurant Space on Main

    Prime restaurant property in a high-traffic, growing tourist area.

    100 W Main St, Walhalla, SC 29691
    View details

    Explore Similar Spaces for Sale in Seneca, SC

    Consider Similar Space for Sale. We found 51 Spaces in Nearby Locations matching your search parameters.

    Seneca Commercial Property with Expansion Potential
    $687,500
    3.95 Acres

    Seneca Commercial Property with Expansion Potential

    High-visibility commercial property ideal for storage, sales, or service center.

    298 Worth St, Seneca, SC 29678
    View details
    Established Hibachi Restaurant for Sale
    $219,000

    Established Hibachi Restaurant for Sale

    Turnkey Hibachi restaurant with existing lease and equipment included.

    1510 Blue Ridge Blvd, Seneca, SC 29672
    View details
    Commercial Property on Radio Station Rd
    $250,000
    0.63 Acres

    Commercial Property on Radio Station Rd

    Commercial property with road frontage, suitable for business location.

    11081 N Radio Station Rd, Seneca, SC 29678
    View details
    Seneca Retail/Warehouse Opportunity
    $1,800,000
    1.01 Acres

    Seneca Retail/Warehouse Opportunity

    All brick/concrete building with existing tenants and expansion potential.

    518 N 1 St, Seneca, SC 29678
    View details
    Historical Brick Building in Seneca
    $999,949

    Historical Brick Building in Seneca

    Three-level, 15,600 SF building in Seneca's Opportunity Zone.

    235 Main St, Seneca, SC 29678
    View details
    Turn-Key Restaurant Franchise Opportunity
    $1,900,000
    0.78 Acres

    Turn-Key Restaurant Franchise Opportunity

    Turn-key national franchise restaurant with real estate for sale.

    1053 By Pass 123 Byp, Seneca, SC 29678
    View details
    Prime Commercial Land Opportunity
    $545,000
    2.65 Acres

    Prime Commercial Land Opportunity

    2.65-acre commercial parcel in high-growth area, ideal for development.

    1800 Sandifer Blvd, Seneca, SC 29678
    View details
    Commercial Land in Seneca, SC
    $325,000
    1.29 Acres

    Commercial Land in Seneca, SC

    Corner lot near downtown Seneca, suitable for various commercial uses.

    911 North 1St St, Seneca, SC 29678
    View details

    Seneca, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Seneca, SC with 67 listings featured on our commercial real estate exchange. The current inventory includes 16,296,144,480 square feet of properties with an estimated lease value of $77 SF/Yr.

    Estimated lease rates for Commercial real estate in Seneca, SC begin at $0.69 SF/Yr, with an average of $11 SF/Yr and extend to $22 SF/Yr.
    List
    Map

    Browse Commercial real estate for Lease Near Seneca, SC

    Popular Searches in Seneca, SC

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!