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Charleston, SC Commercial Real Estate for Lease

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Savannah Highway Retail/Office Space
$30 SF/Yr
4,168 SF

Savannah Highway Retail/Office Space

Freestanding building with excellent visibility and ample parking.

422 Savannah Hwy, Charleston, SC 29407
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Charleston Retail Space with Drive-Thru
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1,952 SF

Charleston Retail Space with Drive-Thru

1,952 SF retail space with drive-thru in Charleston.

221 Spring St, Charleston, SC 29403
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Retail Space Available For Lease
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5,650 SF

Retail Space Available For Lease

Retail property available for lease with 5650 square feet.

1291 Folly Road Blvd, Charleston, SC 29412
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Retail Space Near Harris Teeter
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2,983 SF

Retail Space Near Harris Teeter

Retail space anchored by Harris Teeter in high-growth West Ashley.

3879 W Ashley Cir, Charleston, SC 29414
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Clements Ferry Road Office Space
$20 SF/Yr
1,010 SF

Clements Ferry Road Office Space

Second floor office space available for rent in Charleston.

2414 Clements Ferry Rd, Charleston, SC 29492
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Retail Space on Sam Rittenberg
Contact for pricing

Retail Space on Sam Rittenberg

Retail space in a brick building with high visibility.

2048 Sam Rittenberg Blvd, Charleston, SC 29407
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Downtown Charleston Office Space
$29 SF/Yr

Downtown Charleston Office Space

Office space for rent in Charleston's growing Upper Peninsula.

11 Isabella St, Charleston, SC 29403
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West Ashley Medical Office Space
Contact for pricing
3,000 SF

West Ashley Medical Office Space

3,000 SF office space in the heart of West Ashley.

1027 Physicians Dr, Charleston, SC 29414
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Retail Space on Folly Road
$26 SF/Yr
640 SF

Retail Space on Folly Road

Retail space for lease in a high-traffic shopping center.

915 Folly Rd, Charleston, SC 29412
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Savannah Highway Retail/Office Building
$16 SF/Yr
2,800 SF

Savannah Highway Retail/Office Building

Free-standing 2,800 SF retail or office building for lease.

2413 Savannah Hwy, Charleston, SC 29414
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Renovated Office/Retail Building on East Bay
$30 SF/Yr
3,789 SF

Renovated Office/Retail Building on East Bay

Modern, flexible office/retail space in prime downtown location.

341 East Bay St, Charleston, SC 29401
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Retail Space in Tourist District
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1,876 SF

Retail Space in Tourist District

Retail space in Charleston's premier tourist district.

164 Market St, Charleston, SC 29401
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Class A Office Space Available
$49 SF/Yr
3,851 SF

Class A Office Space Available

Up to 3,851 SF of fully up-fitted Class A office space.

651 Meeting St, Charleston, SC 29403
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Retail Space in Quadrangle Center
$22 SF/Yr
2,000 SF

Retail Space in Quadrangle Center

1,040 SF available in West Ashley shopping center.

630 Skylark Dr, Charleston, SC 29407
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Upper King Street Office Space
$34 SF/Yr
3,204 SF

Upper King Street Office Space

Office space for rent in Charleston's Upper King District.

463 King Street Ext, Charleston, SC 29403
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Retail Space Near Whole Foods
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1,507 SF

Retail Space Near Whole Foods

Retail space available in shopping center anchored by Whole Foods.

1133 Savannah Hwy, Charleston, SC 29407
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Office Space with Harbor Views
$22 SF/Yr
1,600 SF

Office Space with Harbor Views

Corner office suite with views of Charleston Harbor available for rent.

3 Lockwood Dr, Charleston, SC 29401
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Retail/Office Space Near MUSC Health
$32 SF/Yr
1,200 SF

Retail/Office Space Near MUSC Health

Vanilla shell space ideal for retail or office use.

8988 University Blvd, N Charleston, SC 29406
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Office Space Available For Rent
Contact for pricing
3,828 SF

Office Space Available For Rent

Office space for rent, full service, 2,131 square feet.

115 Fairchild St, Charleston, SC 29492
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Office Space Available For Rent
$26 SF/Yr
33,492 SF

Office Space Available For Rent

Office space available for lease with 33492 square feet.

2387 Clements Ferry Rd, Charleston, SC 29492
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Industrial Space Available For Lease
$2 SF/Yr
8,750 SF

Industrial Space Available For Lease

Industrial property featuring 8,750 square feet available for lease.

8008 Dorchester Rd, Charleston, SC 29418
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Explore Similar Spaces for Sale in Charleston, SC

Consider Similar Space for Sale. We found 139 Spaces in Nearby Locations matching your search parameters.

Charleston Medical Property Investment
$1,895,000
5,567 SF

Charleston Medical Property Investment

Thriving medical property in Charleston, SC with favorable lease terms.

2039 Savannah Hwy, Charleston, SC 29407
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Renovated Duplex in Downtown Charleston
$925,000
1,461 SF

Renovated Duplex in Downtown Charleston

Turnkey duplex near MUSC & CofC, completed renovation in 2025.

68 Lee St, Charleston, SC 29403
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King Street Mixed-Use Opportunity
$1,195,000
2,074 SF

King Street Mixed-Use Opportunity

Storefront business with upstairs living in a rapidly growing downtown location.

680 King Street Ext, Charleston, SC 29403
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