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    Anderson County, SC Commercial Real Estate for Lease

    52 results
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    Historic Building in Pendleton Square
    $3,100 / Mo

    Historic Building in Pendleton Square

    102 Exchange St, Pendleton, SC 29670

    Iconic building in vibrant Pendleton, SC, near Clemson University.

    • Prominent location on the vibrant Town Square in Pendleton, SC.
    • Historic building with planned authentic restoration and modern updates.
    • Currently leased to retail and professional office businesses, providing immediate income.
    • Close proximity to Clemson University.
    • Located in a charming town business district with restaurants, art galleries, bakeries, and gift shops.
    Updated: Dec 26, 2025
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    Class A Office Space
    $3,400 / Mo

    Class A Office Space

    2315 N Main St, Anderson, SC 29621

    Professional office suite for rent in Anderson, SC.

    • Prime Main Street location ideal for high‑visibility professional business.
    • Class A office building with included maintenance, electric, and water.
    • Versatile 2,800 sq ft suite suitable for medical or professional use.
    • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
    • Includes a welcoming reception area and large parking space.
    Updated: Dec 9, 2025
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    Downtown Anderson Commercial Space Available
    $1,500 / Mo
    2,614 SF

    Downtown Anderson Commercial Space Available

    Versatile 1,300 SF space in historic downtown Anderson.

    122 W Whitner St, Anderson, SC 29624
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    Industrial Building in Anderson, SC
    $5,500 / Mo

    Industrial Building in Anderson, SC

    Industrial building suitable for wholesale distribution in Anderson, SC.

    1821 S Mcduffie St, Anderson, SC 29624
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    Market Fair Shopping Center: Prime Retail Space
    Contact for pricing
    33,000 SF

    Market Fair Shopping Center: Prime Retail Space

    33,000 SF Retail Space - Anderson County

    3795 Clemson Blvd, Anderson, SC 29621
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    Main Street Retail Mall Opportunity
    $1.00 SF/Yr
    190,000 SF

    Main Street Retail Mall Opportunity

    Anderson, SC Shopping Mall - 190,000 SF

    3131 Main St, Anderson, SC 29621
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    Schmid Plaza Road Warehouse
    $3 SF/Yr
    149,555 SF

    Schmid Plaza Road Warehouse

    Anderson, SC industrial space available

    201 Schmid Plaza Rd, Anderson, SC 29624
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    Belton Assisted Living Facility
    $12 SF/Yr
    6,700 SF

    Belton Assisted Living Facility

    Rare 6,700 SF Assisted Living

    250 Union High Dr, Belton, SC 29627
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    Anderson Retail Strip - For Lease
    $10 SF/Yr
    29,040 SF

    Anderson Retail Strip - For Lease

    High-visibility retail spaces available

    1402 River St, Anderson, SC 29624
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    Anderson Mall Retail Space For Lease
    Contact for pricing
    576,450 SF

    Anderson Mall Retail Space For Lease

    High-traffic retail space in Anderson, SC.

    3131 Main St, Anderson, SC 29621
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    Oak Point Plaza Executive Suites
    $20 SF/Yr
    57,107 SF

    Oak Point Plaza Executive Suites

    Anderson, SC Office Space Available

    4120-4126 Clemson Blvd, Anderson, SC 29621
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    Anderson Retail Space - Fritz Drive
    Contact for pricing
    15,000 SF

    Anderson Retail Space - Fritz Drive

    Prime Anderson SC Retail Opportunity

    128 Fritz Dr, Anderson, SC 29621
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    Downtown Anderson Retail Space
    $10 SF/Yr
    5,300 SF

    Downtown Anderson Retail Space

    Iconic 5,300 sqft space, prime location.

    110 Greenville St, Anderson, SC 29621
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    Belvedere Plaza Retail Space For Lease
    Contact for pricing
    151,985 SF

    Belvedere Plaza Retail Space For Lease

    Anderson, SC Shopping Center Opportunity

    3100 Main St, Anderson, SC 29621
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    Belton Office Building For Lease
    Contact for pricing
    1,345 SF

    Belton Office Building For Lease

    1,345 sq ft Office Space in Belton, SC

    250 Union High Dr, Belton, SC 29627
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    Prime Anderson County Retail Space
    $4 SF/Yr
    54,150 SF

    Prime Anderson County Retail Space

    Grocery-anchored retail center; multiple spaces available.

    605 Main St, Belton, SC 29627
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    Anderson SC Shopping Center
    Contact for pricing
    80,097 SF

    Anderson SC Shopping Center

    High-traffic retail space available.

    3420 Clemson Blvd, Anderson, SC 29621
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    Pelzer Industrial Barn Lease
    $3 SF/Yr
    31,000 SF

    Pelzer Industrial Barn Lease

    Spacious barn & office, ideal for various uses.

    186 Woodville Rd, Pelzer, SC 29669
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    Prime Anderson Office Space
    $25 SF/Yr
    1,212 SF

    Prime Anderson Office Space

    1,800 sq ft Office in High-Traffic Area

    1107 Fant St, Anderson, SC 29621
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    Clemson Blvd Retail Center
    $15 SF/Yr
    8,400 SF

    Clemson Blvd Retail Center

    Anderson, SC: 1,500 SF Available

    4132 Clemson Blvd, Anderson, SC 29621
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    Pendleton Industrial Warehouse Space
    $3 SF/Yr
    420,000 SF

    Pendleton Industrial Warehouse Space

    Large warehouse space available for lease or sale.

    290 Old Anderson Rd, Pendleton, SC 29670
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    Prime Anderson Industrial Space
    Contact for pricing
    125,000 SF

    Prime Anderson Industrial Space

    Modern Manufacturing/Warehouse, 125,000 SF

    230 Masters Blvd, Anderson, SC 29626
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    Retail Space in Power Center
    Contact for pricing
    1,200 SF

    Retail Space in Power Center

    Retail space available in a busy power center.

    172 Station Dr, Anderson, SC 29621
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    Industrial Space Near I-85
    Contact for pricing
    25,000 SF

    Industrial Space Near I-85

    25,000 SF industrial space with I-85 frontage.

    9 Red Fox Blvd, Williamston, SC 29697
    View details

    Anderson County, SC Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Anderson County, SC with 151 listings featured on our commercial real estate exchange. The current inventory includes 43,673,499,940 square feet of properties with an estimated lease value of $248 SF/Yr.

    Estimated lease rates for Commercial Real Estate in Anderson County, SC begin at $1.00 SF/Yr, with an average of $10 SF/Yr and extend to $25 SF/Yr.

    In Anderson County, SC, current lease rates show:

    • Retail properties positioned at $9
    • Industrial properties measuring $7
    • Office Properties & Spaces assessed at $15
    • Other warehouses calculated at $7
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    Browse Commercial real estate for Lease Near Anderson, SC

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