Add Listing
    Anderson, SC
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Anderson, SC Office Units for Lease

    Notify Me
    List
    Map
    Belton, SC Pendleton, SC Williamston, SC
    16 results
    Class A Office Space
    $3,400/Mo
    Class A Office Space

    2315 N Main Street, Anderson, SC 29621

    Professional office suite for rent in Anderson, SC.
    • Prime Main Street location ideal for high‑visibility professional business.
    • Class A office building with included maintenance, electric, and water.
    • Versatile 2,800 sq ft suite suitable for medical or professional use.
    • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
    • Includes a welcoming reception area and large parking space.
    Updated: Nov 13, 2025
    View details
    Retail Space in Whitehall Commons
    $13 SF/Yr
    1,200 SF
    Retail Space in Whitehall Commons

    1486 Pearman Dairy Road, Anderson, SC 29625

    Retail or office space available in a high-traffic area.
    • Located at a high‑traffic intersection (Pearman Dairy Road & Whitehall Road) with combined traffic counts exceeding 35,000 VPD.
    • Excellent visibility and access due to its location at a red light corner behind McDonald's.
    • Benefits from co‑tenancy within Whitehall Commons, a +/- 8400 SF center with a mix of local and regional tenants.
    • Ample parking and multiple points of access for customers.
    • Strong retail trade area with proximity to national brand retailers including McDonald's, Arby's, QuikTrip, and a new Starbucks.
    Updated: Mar 5
    View details
    Office Suite with High-End Finishes
    $18 SF/Yr
    1,800 SF
    Office Suite with High-End Finishes

    Well-finished office suite with private offices, conference space, ample parking, and strong visibility for professional teams.

    1801 North Main Street, Anderson, SC 29621

    View details
    Flex Building with Office, Warehouse
    $4,000/Mo
    3,200 SF
    Flex Building with Office, Warehouse

    Flex building with office and warehouse space for lease.

    109 Old Denver Road, Anderson, SC 29625

    View details
    Miracle Mile Commercial Building
    $9 SF/Yr
    4,000 SF
    Miracle Mile Commercial Building

    Approximately 4000 SF building for lease with high visibility.

    102 Miracle Mile Dr, Anderson, SC 29621

    View details
    Renovated Office Building For Rent
    $1,300/Mo
    1,300 SF
    Renovated Office Building For Rent

    Renovated office building with versatile space for rent.

    1311 South Murray Avenue, Anderson, SC 29624

    View details
    Office Space Near Downtown Anderson
    $1,300/Mo
    900 SF
    Office Space Near Downtown Anderson

    Office suite with three private offices, reception, and kitchenette.

    1214 North Main Street, Anderson, SC 29621

    View details
    Renovated Office/Retail Space Available
    $15 SF/Yr
    1,200 SF
    Renovated Office/Retail Space Available

    Newly renovated 1,200 SF office/retail space for lease.

    1207 Whitehall Road, Anderson, SC 29625

    View details
    Office Space Available for Lease
    $15 SF/Yr
    Office Space Available for Lease

    Office space available for lease in Anderson, SC.

    309 E Greenville St, Anderson, SC 29621

    View details
    Former Bank Branch with Drive-Thru
    $18 SF/Yr
    Former Bank Branch with Drive-Thru

    Former bank branch with drive-thru located near major retailers.

    3898 Liberty Highway, Anderson, SC 29621

    View details
    East Greenville Street Office Space
    Contact for pricing
    2,000 SF
    East Greenville Street Office Space

    Office or medical suite with ample parking and high visibility.

    1403 East Greenville Street, Anderson, SC 29621

    View details
    Office Space with Recent Upgrades
    $5,000/Mo
    4,200 SF
    Office Space with Recent Upgrades

    Office space featuring new exterior paint and resurfaced parking lot.

    120 E West Pkwy, Anderson, SC

    View details
    Office Space Available For Rent
    Contact for pricing
    4,550 SF
    Office Space Available For Rent

    Office space available with 4,550 square feet in Anderson.

    131 Straight Dr, Anderson, SC 29625

    View details
    Professional Office Space Available
    Contact for pricing
    3,000 SF
    Professional Office Space Available

    Well-maintained office park near US 178/N. Main St.

    341 E Beltline Blvd, Anderson, SC

    View details
    Oak Point Plaza Retail Opportunity
    $12 SF/Yr
    57,107 SF
    Oak Point Plaza Retail Opportunity

    Multi-tenant plaza near I-85 and Clemson University for lease.

    4120-4126 Clemson Blvd, Anderson, SC 29621

    View details
    Prime Commercial Space in Anderson
    $14 SF/Yr
    1,200 SF
    Prime Commercial Space in Anderson

    Newly renovated commercial space with high visibility on Pearman Dairy Road.

    1716 Pearman Dairy Rd, Anderson, SC 29625

    View details
    Based on your search, we've compiled 36 Potential Opportunities for your consideration. Besides 16 Active listings in Anderson, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 16 Properties for Sales.

    Office Units for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Piedmont Commercial Office Space
    $1,650/Mo
    Piedmont Commercial Office Space

    1,200 SF office space with high visibility and accessibility.

    2514 River Road, Piedmont, SC 29673

    View details
    Seneca Retail/Office Space Available
    $1,700/Mo
    712 SF
    Seneca Retail/Office Space Available

    Retail/office space for lease in Seneca, SC. Renovated and visible.

    1109 Jennings Ave Unit A, Seneca, SC 29768

    View details
    Seneca Office Space For Lease
    $1,500/Mo
    Seneca Office Space For Lease

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Highway, Seneca, SC 29678

    View details
    Industrial Space Available for Lease
    Contact for pricing
    12,000 SF
    Industrial Space Available for Lease

    12,000 SF industrial space featuring office and warehouse components.

    110 Prosperity Blvd, Piedmont, SC 29673

    View details

    Similar Spaces for Sale in Anderson, SC

    Consider Similar Space for Sale. We found 16 Spaces matching your search parameters.

    Commercial Property Near Downtown Anderson
    $429,000
    0.64 Acres
    Commercial Property Near Downtown Anderson

    Well-maintained flex building with office and warehouse space.

    3499 East River Street, Anderson, SC 29621

    View details
    Warehouse & Flex Space Facility
    $425,000
    3.11 Acres
    Warehouse & Flex Space Facility

    Clear-span warehouse with flex-style potential, roll-up loading, and commercial/industrial zoning for a range of operations.

    109 Waybrook Drive, Anderson, SC 29624

    View details
    Office Building with Multiple Entrances
    $499,000
    0.25 Acres
    Office Building with Multiple Entrances

    Move-in-ready office property with paved front and rear parking, a heated/cooled sunroom, and flexible room layout.

    2006 N Main Street, Anderson, SC 29621

    View details
    Office Cottage Near Downtown Anderson
    $215,000
    1,400 SF
    Office Cottage Near Downtown Anderson

    Office space near downtown, AnMed Hospital, and Anderson University.

    609 Bonham Court, Anderson, SC 29621

    View details
    Versatile Mixed-Use Commercial Property
    $750,000
    0.48 Acres
    Versatile Mixed-Use Commercial Property

    Over 5,000 sq ft commercial property with residential area.

    4327 Old Mill Road, Anderson, SC 29623

    View details
    Anderson Flex Space Opportunity
    $115,999
    2,150 SF
    Anderson Flex Space Opportunity

    2,150 SF flex space near downtown Anderson for sale.

    1819 W Whitner St, Anderson, SC 29624

    View details
    Residential Office with In-Law Suite
    $395,000
    Residential Office with In-Law Suite

    Brick home with finished basement, second kitchen, and separate entrance, offering flexible live/work and professional office potential.

    510 E Calhoun Street, Anderson, SC 29621

    View details
    Prime Corner Lot on Hwy 24
    $799,000
    1.22 Acres
    Prime Corner Lot on Hwy 24

    1.22-acre corner lot ideal for QSR, Retail, or Office.

    00 Hwy 24, Anderson, SC 29626

    View details

    Anderson, SC Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Anderson, SC with 16 listings featured on our commercial real estate exchange. The current inventory includes 74,307 square feet of properties with an estimated lease value of $123 SF/Yr.

    Estimated lease rates for Office Units in Anderson, SC begin at $9 SF/Yr, with an average of $13 SF/Yr and extend to $17 SF/Yr.
    List
    Map

    Popular Searches in Anderson, SC

    Popular Categories

    Most Searched ZIP Codes in Anderson, SC

    • 29621
    • 29625
    • 29624

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!