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    Durham County, NC Commercial Real Estate for Lease

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    Charlotte, NC Raleigh, NC Greensboro, NC
    133 results
    NC, Durham - Spaces Mangum Street
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    NC, Durham - 3511 Shannon Road
    $129-$2,998/Mo

    NC, Durham - 3511 Shannon Road

    3511 Shannon Rd, Durham, NC 27707

    Discover many ways to work your way in NC, Durham - 3511 Shannon Road

    • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
    • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
    • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
    • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
    • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
    Updated: Feb 19
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    RTP Imperial
    $129-$3,608/Mo

    RTP Imperial

    4819 Emperor Blvd, Unit 400, Durham, NC 27703

    Discover many ways to work your way in RTP Imperial

    • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
    • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
    • Access HQ' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
    • Impress clients, hold memorable workshops, and deliver a winning pitch in HQ' meeting spaces, fully equipped for gatherings of any size
    • Collaborate with like‑minded professionals and enjoy regular networking and community events with a HQ membership
    Updated: Feb 9
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    Durham Office Space For Lease
    $45,045 SF/Yr
    2,145 SF

    Durham Office Space For Lease

    Flexible office unit with ample parking and recent upgrades.

    1906 Carolina 54, Durham, NC 27713
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    Durham Medical/Office Building for Lease
    $23 SF/Yr
    4,769 SF

    Durham Medical/Office Building for Lease

    Freestanding 4,769 SF building suitable for medical or office use.

    110 E. Carver Street, Durham, NC 27704
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    Professional Office Condos For Lease
    $2,400/Mo
    5,120 SF

    Professional Office Condos For Lease

    Office condos for lease near Duke University Medical Center.

    2741 Campus Walk Ave, Building 400, Durham, NC 27705
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    Versatile Building Available for Lease/Sale
    $3,950,000 SF/Yr
    9,790 SF

    Versatile Building Available for Lease/Sale

    Adaptable building suitable for restaurant, fitness, or office use.

    211 Rigsbee Ave, Durham, NC 27701
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    Prime Medical Office Space Available
    $18 SF/Yr
    2,312 SF

    Prime Medical Office Space Available

    Versatile medical/office space in Durham's thriving North Duke corridor.

    2609 N Duke Street, Durham, NC 27704
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    Plug and Play Lab Space
    $30 SF/Yr
    94,603 SF

    Plug and Play Lab Space

    Move-in ready lab and office space in Durham, NC.

    4025 Stirrup Creek Drive, Durham, NC 27703
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    Roxboro Road Professional Office Space
    $20 SF/Yr
    2,408 SF

    Roxboro Road Professional Office Space

    Office space ideal for professional services and medical offices.

    4210 N. Roxboro Street, Suite 140, Durham, NC 27704
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    Durham Office and Retail Space
    $27 SF/Yr
    16,679 SF

    Durham Office and Retail Space

    Office and retail suites available for lease in Durham.

    404 Hunt Street, Durham, NC 27701
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    Retail Space on N Duke
    $3,000/Mo
    2,400 SF

    Retail Space on N Duke

    Retail space available for rent on N Duke Street.

    3925 N Duke Street 121, Durham, NC 27704
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    RTP Meridian
    $119-$3,403/Mo

    RTP Meridian

    Discover many ways to work your way in RTP Meridian

    2530 Floors, Durham, NC 27713
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    Historic Brick Building in Durham
    $33 SF/Yr
    19,931 SF

    Historic Brick Building in Durham

    Historic 91,168 SF brick building in Durham's Warehouse District.

    333 Liggett Street, Durham, NC 27701
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    Class A Office Space
    $23 SF/Yr
    79,440 SF

    Class A Office Space

    Class A office space for lease in North Durham.

    4321 Medical Park Dr, Durham, NC 27704
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    Office/Medical Building Near Southpoint Mall
    $26 SF/Yr
    18,395 SF

    Office/Medical Building Near Southpoint Mall

    Single-story office/medical building near Southpoint Mall available for lease.

    5501 Fortunes Ridge Drive, Durham, NC 27713
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    Office Space Available For Rent
    $34 SF/Yr
    18,502 SF

    Office Space Available For Rent

    Office space for rent with convenient parking and amenities.

    215 Morris Street, Durham, NC 27701
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    Downtown Durham Office Space Available
    $32 SF/Yr
    25,678 SF

    Downtown Durham Office Space Available

    Suites available in historic Art Deco building, downtown Durham.

    331 W Main Street, Durham, NC 27707
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    Downtown Durham Office Space Available
    $29 SF/Yr
    32,522 SF

    Downtown Durham Office Space Available

    Move-in ready office space in downtown Durham with modern amenities.

    505 S Duke St, Durham, NC 27701
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    Luxury Mixed-Use Development Near Duke
    $25 SF/Yr
    118,000 SF

    Luxury Mixed-Use Development Near Duke

    Class A mixed-use development near Duke University and hospitals.

    2812 & 2816 Erwin Rd |, Durham, NC 27705
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    Durham Flex Space Available
    $13 SF/Yr
    35,000 SF

    Durham Flex Space Available

    35,000 SF flex space for rent in Durham.

    4808 Chin Page Rd, Durham, NC 27703
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    Downtown Durham Office Space Available
    Contact for pricing
    16,692 SF

    Downtown Durham Office Space Available

    Office spaces for lease in the heart of downtown Durham.

    433 W. Main Street, Durham, NC 27701
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    North Durham Retail Space Available
    Contact for pricing
    22,425 SF

    North Durham Retail Space Available

    Retail and restaurant spaces available in North Durham power center.

    3500 North Roxboro Street, Durham, NC 27704
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    Retail Space Near RTP
    $3,232/Mo
    1,168 SF

    Retail Space Near RTP

    Retail space in a vibrant neighborhood center near RTP.

    5125 Nc-55, Durham, NC 27713
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    Durham County, NC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Durham County, NC with 133 listings featured on our commercial real estate exchange. The current inventory includes 714,375 square feet of properties with an estimated lease value of $3,996,264.

    Estimated lease rates for Commercial real estate in Durham County, NC begin at $5 SF/Yr, with an average of $117,537 and extend to $3,950,000.
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