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Niles, MI Commercial Real Estate for Lease

9 results
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Downtown Niles Private Office Suite
$35 SF/Yr
200 SF

Downtown Niles Private Office Suite

306 E Main St, Niles, MI 49120

Private office suite available in downtown Niles, all utilities included.

  • Private office suite in downtown Niles.
  • Rent of $575/month includes all utilities (except internet).
  • Enjoy central air conditioning.
  • Forced air heating.
  • Features a fireplace.
Updated: Oct 29, 2025
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Downtown Niles Flex Office Space
$12 SF/Yr
1,041 SF

Downtown Niles Flex Office Space

302 E Main St, Niles, MI 49120

Flex office or studio space available in downtown Niles.

  • Open flex office/studio space ideal for remote work or starting a business.
  • Located in downtown Niles.
  • Central air conditioning.
  • Forced air heating.
  • Fireplace included.
Updated: Nov 11, 2025
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Former Restaurant with Extra Parking
$25 SF/Yr
3,140 SF

Former Restaurant with Extra Parking

Restaurant space with additional lot available for sublease.

1295 S 11Th St, Niles, MI 49120
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Simplicity Building: Niles, MI Industrial Space
$4 SF/Yr
497,091 SF

Simplicity Building: Niles, MI Industrial Space

497,091 SF Warehouse/Manufacturing Space Available

901 Wayne St, Niles, MI 49120
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Niles Industrial Plant - 70,946 SF
$3 SF/Yr
70,946 SF

Niles Industrial Plant - 70,946 SF

Large Manufacturing Space Available

1313 Airport Rd, Niles, MI 49120
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Niles, MI Office Suites Available
$15 SF/Yr
15,800 SF

Niles, MI Office Suites Available

Downtown Niles office space, flexible sizes.

306 Main St, Niles, MI 49120
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Retail Space with Drive-Thru Potential
$19 SF/Yr
3,000 SF

Retail Space with Drive-Thru Potential

Retail space with high traffic and national co-tenants.

2714 S 11Th St, Niles, MI 49120
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Retail Space with Drive-Thru Potential
$19 SF/Yr
3,000 SF

Retail Space with Drive-Thru Potential

Retail space with high traffic and drive-thru potential.

2726 S 11Th St, Niles, MI 49120
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Industrial Space Available for Lease
$5 SF/Yr
25,000 SF

Industrial Space Available for Lease

25,000 square foot industrial property for lease.

2232 South 11Th St, Niles, MI 49120
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Based on your search, we've compiled 40 Potential Opportunities for your consideration. Besides 9 Active listings in Niles, MI, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 27 Properties for Sales.

Explore Commercial Real Estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Wedgewood Plaza Retail Center
$8 SF/Yr
152,334 SF

Wedgewood Plaza Retail Center

South Bend, IN Strip Mall - High Traffic Location

50630 State Hwy 933, South Bend, IN 46637
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South Bend Auto Repair Site
$40 SF/Yr
3,000 SF

South Bend Auto Repair Site

3,000 SF Freestanding Building, High Traffic

50860 State Hwy 933, South Bend, IN 46637
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Industrial Space for Rent
$4 SF/Yr
33,000 SF

Industrial Space for Rent

Industrial property in Buchanan, Michigan, offering flexible space and loading docks.

600 Cecil St, Buchanan, MI 49107
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Multi-Use Commercial Property in Buchanan
$5 SF/Yr
10,914 SF

Multi-Use Commercial Property in Buchanan

Versatile property suitable for distribution, manufacturing, offices, retail.

402 S Oak St, Buchanan, MI 49107
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Explore Similar Spaces for Sale in Niles, MI

Consider Similar Space for Sale. We found 27 Spaces in Nearby Locations matching your search parameters.

Historic Niles Building with Gym
$975,000
11,696 SF

Historic Niles Building with Gym

Fully occupied historic building in downtown Niles with steady income.

115 E Main St, Niles, MI 49120
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Adaptable Office/Medical Space Near Downtown
$950,000
5,280 SF

Adaptable Office/Medical Space Near Downtown

Updated office/medical space near downtown Niles and the hospital.

122 Grant St, Niles, MI 49120
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Niles Commercial Property with Acreage
$650,000
8,600 SF

Niles Commercial Property with Acreage

Versatile commercial property with multiple buildings and flexible space.

1115 Stateline Rd, Niles, MI 49120
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Versatile Commercial Building in Niles
$399,000
3,680 SF

Versatile Commercial Building in Niles

3,600+ sq. ft. commercial building in downtown Niles, MI

920 Lambert St, Niles, MI 49120
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Commercially Zoned Building in Niles
$179,900
2,430 SF

Commercially Zoned Building in Niles

Office, retail, distribution, storage, or professional service use.

224 N 4Th St, Niles, MI 49120
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Niles Grow Facility on 4+ Acres
$495,000
40,000 SF

Niles Grow Facility on 4+ Acres

Niles, Michigan grow facility with greenhouses on over 4 acres.

1430 S 3Rd St, Niles, MI 49120
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Versatile Commercial Property on High-Traffic Street
$515,000
3,200 SF

Versatile Commercial Property on High-Traffic Street

40x80 commercial property with live/work space and ample parking.

2604 S 11Th St, Niles, MI 49120
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Entertainment Center with Bowling Alley
$2,000,000
17,628 SF

Entertainment Center with Bowling Alley

Family-friendly entertainment center with bowling, arcade, sports bar.

2732 S 11Th St, Niles, MI 49120
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Retail Property in Niles, MI
$250,000
7,280 SF

Retail Property in Niles, MI

Retail property available for sale in Niles, Michigan.

2314 N 5Th St, Niles, MI 49120
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Wheelchair Accessible Multi-Unit Property
$690,000
5,791 SF

Wheelchair Accessible Multi-Unit Property

Well-maintained triplex with retail potential, near Notre Dame.

2639 S 3Rd St, Niles, MI 49120
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Wheelchair Accessible Multi-Unit Property
$690,000

Wheelchair Accessible Multi-Unit Property

Well-maintained triplex with upgrades, potential for retail or business.

2639 S 3Rd St, Niles, MI 49120
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Updated Niles Triplex with Accessibility
$690,000
5,791 SF

Updated Niles Triplex with Accessibility

Triplex with upgrades, income potential, and wheelchair accessibility.

2639 S 3Rd St, Niles, MI 49120
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Well-Maintained Home on Double Lot
$50,000

Well-Maintained Home on Double Lot

1988 manufactured home with updates, carport, and storage sheds.

1950 S 13Th St, Niles, MI 49120
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Updated Mobile Home in Park
$60,000

Updated Mobile Home in Park

Updated 3-bedroom, 2-bath mobile home in a peaceful park.

2006 Ontario Rd, Niles, MI 49120
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High-Traffic Retail Opportunity For Sale
$800,000

High-Traffic Retail Opportunity For Sale

Prime retail location with high visibility and accessibility.

2645 S 11Th St, Niles, MI 49120
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Niles, MI Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Niles, MI with 36 listings featured on our commercial real estate exchange. The current inventory includes 27,286,855,200 square feet of properties with an estimated lease value of $168 SF/Yr.

Estimated lease rates for Commercial Real Estate in Niles, MI begin at $3 SF/Yr, with an average of $15 SF/Yr and extend to $35 SF/Yr.

In Niles, MI, current lease rates show:

  • Individual retail properties positioned at $19
  • Industrial properties measuring $6
  • Office Properties & Spaces assessed at $19
  • Retail properties calculated at $19
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