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    Middlesex County, MA Commercial Real Estate for Lease

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    2,131 properties
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    Second-Floor Office Suite With Elevator
    Updated: Jul 23
    Second-Floor Office Suite With Elevator

    10 High Street, Medford, MA 02155

    $1,500/Mo
    663 sqft
    1,325 SF second‑floor space across two units
    Can be leased separately: Unit #10 and Unit #12
    Large reception area plus spacious conference room
    Kitchen with work space and eating area, plus 3 separate offices
    Elevator access and shared deck with Mystic River views
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    Second-Floor Office Units with Deck
    Updated: Jul 23
    Second-Floor Office Units with Deck

    10 High Street, Medford, MA 02155

    $1,500/Mo
    662 sqft
    Two second‑floor office units totaling 1,325 SF
    Can be leased together or separately
    Unit #10: reception/work/admin area plus conference room
    Unit #12: kitchen/work area plus 3 separate offices
    Elevator access and shared deck with Mystic River views
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    Second-Floor Office Suite with Elevator Access
    Second-Floor Office Suite with Elevator Access

    10 High Street, Medford, MA 02155

    $3,000/Mo
    1,325 sqft

    Flexible second-floor office space with reception, conference room, kitchen area, and three offices, accessible by elevator.

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    Retail Space with Office Use
    Retail Space with Office Use

    222 Arsenal St, Watertown, MA 02472

    $30 SF/Yr
    2,500 sqft

    I-3-zoned commercial space offers a flexible retail-office configuration.

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    Office Suite With Open Workspace
    Office Suite With Open Workspace

    24 Thorndike Street, Cambridge, MA 02141

    $32 SF/Yr
    1,800 sqft 0.13 AC lot

    Move-in ready office accommodation includes private windowed offices, a kitchenette, and dedicated onsite parking available as an option.

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    Furnished Plug-and-Play Office Suite
    Furnished Plug-and-Play Office Suite

    24 Thorndike Street, Cambridge, MA 02141

    $40 SF/Yr
    3,250 sqft

    Configured with open work areas, conference space, private rooms, reception, kitchenette, and two restrooms.

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    Retail Storefront with Ramp Access
    Retail Storefront with Ramp Access

    99 Massachusetts Avenue, Arlington, MA 02474

    $3,500/Mo
    1,051 sqft

    Retail storefront for lease with private entrance ramp and private bathroom in an updated East Arlington setting.

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    Historic Office Units with Elevator
    Historic Office Units with Elevator

    10 Common Road, Ashby, MA 01431

    $1,500/Mo
    3,270 sqft

    Flexible commercial suites in a restored multi-tenant building with onsite parking, storage, signage, and access to shared amenities.

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    Office Units with Private Entrance
    Office Units with Private Entrance

    2 University Road, Cambridge, MA 02138

    $39 SF/Yr
    2,931 sqft 0.43 AC lot

    Flexible office layout with private access, meeting rooms, open work areas, and a shared kitchenette.

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    Retail or Office Space
    Retail or Office Space

    1103 Cambridge Street, Cambridge, MA 02139

    $3,000/Mo
    508 sqft

    New construction commercial suite offered for retail, office, studio, or boutique service use, available September 1.

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    Downtown Main Street Medical Office
    Downtown Main Street Medical Office

    649 Main Street, Waltham, MA 02451

    $27 SF/Yr
    3,890 sqft

    Renovated two-story suite with ADA-compliant restrooms, private treatment/offices, and separate rear access for flexible healthcare use.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    26 New St, Cambridge, MA 02138

    $25 SF/Yr
    3,000 sqft 1.19 AC lot

    Configured with open work areas, private offices, conference rooms, and a kitchen.

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    Office Suite with Natural Light
    Office Suite with Natural Light

    545 Concord Ave, Cambridge, MA 02138

    $40 SF/Yr
    1,925 sqft 0.24 AC lot

    Windowed offices include reception, storage, and a kitchenette within an accessible elevator building.

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    Full-Floor Office Unit
    Full-Floor Office Unit

    6-288 Walnut St, Newton, MA 02460

    $24 SF/Yr
    4,000 sqft

    Renovated professional space with private elevator access, parking, and commuter rail service at the property.

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    Office Suite in Elevator Building
    Office Suite in Elevator Building

    552 Massachusetts Ave, Cambridge, MA 02139

    $45 SF/Yr
    1,250 sqft 0.27 AC lot

    Wheelchair-accessible office suite with 24/7 access, conference room, and kitchenette near Central Square on the MBTA Red Line.

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    Renovated Office Suite
    Renovated Office Suite

    810 Memorial Dr, Cambridge, MA 02139

    $48 SF/Yr
    2,442 sqft 2.77 AC lot

    Third-floor workspace with river views, transit access, shared amenities, and on-site building services.

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    First-Floor Retail Suite
    First-Floor Retail Suite

    1-171 Cambridge St, Burlington, MA 01803

    $3,500/Mo
    4,800 sqft

    Commercial space with on-site parking and convenient connections to Route 3 and I-95/Route 128.

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    Renovated Office Units
    Renovated Office Units

    810 Memorial Dr, Cambridge, MA 02139

    $48 SF/Yr
    443 sqft 2.77 AC lot

    Second-floor offices offer accessible workspace with transit connections, shared amenities, and on-site building services.

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    Flex Office Space with Parking
    Flex Office Space with Parking

    385 Pleasant St, Watertown, MA 02472

    $25 SF/Yr
    3,700 sqft

    Versatile flex/office space with a flexible layout and 15 parking spaces, just across from the Charles River.

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    Class A Office Unit
    Class A Office Unit

    185 Alewife Brook Pkwy, Cambridge, MA 02138

    $45 SF/Yr
    2,080 sqft 0.96 AC lot

    Windowed offices, meeting rooms, open workspace, reception, and kitchenette in an accessible elevator building.

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    Restaurant Space with Bar
    Restaurant Space with Bar

    101 Broadway Road, #19, Dracut, MA 01826

    $5,100/Mo
    5,100 sqft

    Restaurant premises with dining, bar, and kitchen areas within an office and retail plaza on Broadway Road.

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    Office Suite with 24/7 Access
    Office Suite with 24/7 Access

    552 Massachusetts Ave, Cambridge, MA 02139

    $45 SF/Yr
    1,500 sqft 0.27 AC lot

    Office suite with large open area, conference room, three interior offices, and shared kitchen, plus 24/7 card access.

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    Downtown Office Suite with Private Entrance
    Downtown Office Suite with Private Entrance

    27 Prescott St #2, Lowell, MA 01852

    $13 SF/Yr
    4,000 sqft

    Office suite includes private entrance, reception, five offices, conference room, and kitchenette with elevator access.

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    Office Units with Private Entrance
    Office Units with Private Entrance

    6 University Road, Cambridge, MA 02138

    $39 SF/Yr
    2,239 sqft 0.43 AC lot

    Flexible office layout includes multiple enclosed rooms, open workspace, and a kitchenette within PUD-1 zoning.

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    Middlesex County, MA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Middlesex County, MA with 2131 listings featured on our commercial real estate exchange. The current inventory includes 29,251,534 square feet of properties with an estimated lease value of $14,748.

    Estimated lease rates for Commercial real estate in Middlesex County, MA begin at $2.42 SF/Yr, with an average of $30.28 SF/Yr and extend to $250 SF/Yr.
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