Natick, MA Commercial Real Estate for Lease

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57 properties
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Third-Floor Office Suite
Updated: Jul 8
Third-Floor Office Suite

3-34 Main St, Natick, MA 01760

$19.25 SF/Yr
3,705 sqft
Third‑floor office suite in an elevator building
Mix of private offices and open collaborative workspace
Kitchenette and two bathrooms within the suite
Located in Natick Center at 3‑34 Main St
Walkable access to shops, restaurants, and public transportation
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Renovated Office Suite with Elevator
Updated: Jun 19
Renovated Office Suite with Elevator

210-4 Mechanic St, Natick, MA 01760

$1,500/Mo
950 sqft
Fully renovated Class A/B office building with elevator service and ADA‑compliant access
Available suite includes a private reception/waiting area
Abundant natural light and attractive window lines throughout the available space
Common lavatories available
Ample on‑site parking for tenants and visitors
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Natick Center Commercial Space Available
Natick Center Commercial Space Available

31 S Main St #B2, Natick, MA 01760

$900/Mo
625 sqft

Lower level commercial space in Natick Center for rent.

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Second-Floor Office Unit
Second-Floor Office Unit

209 West Central Street, #216, Natick, MA 01760

$20 SF/Yr
315 sqft

Bright, efficient layout includes a reception area and private office for a small business or individual.

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Second-Floor Office Suite
Second-Floor Office Suite

216-209 W Central St, Natick, MA 01760

$20 SF/Yr
315 sqft

Compact workspace with reception and a private office for a small business or individual.

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Natick Commercial Space For Lease
Natick Commercial Space For Lease

R-63 Washington Ave, Natick, MA 01760

$1,700/Mo
1,500 sqft

1,500 Sq Ft light industrial/commercial space for lease.

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Natick Office/Fitness Space Available
Natick Office/Fitness Space Available

19 Willow St, Natick, MA 01760

$21 SF/Yr
7,000 sqft

7000 SF space suitable for office or fitness use.

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Furnished Flex Lab & Office
Furnished Flex Lab & Office

5 Strathmore Rd, Natick, MA 01760

Contact for pricing
10,000 sqft

Fully furnished flex layout with office and R&D/testing/assembly space, plus loading dock and ample on-site parking.

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Lab/Office Sublease Space
Lab/Office Sublease Space

1 Strathmore Road, Natick, MA 01760

Contact for pricing
10,201 sqft

Sublease-ready lab/office space with convenient highway access and proximity to the airport for corporate and R&D teams.

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Large Lot Retail Space
Large Lot Retail Space

321 Speen St, Natick, MA 01760

Contact for pricing
16,000 sqft 15.71 AC lot

Standalone retail space with ample land area available for lease in Natick, MA.

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Coworking Office and Lab Space
Coworking Office and Lab Space

21 Strathmore Rd, Natick, MA 01760

$2,000/Mo per office

Move-in ready coworking suite with shared conference rooms and kitchens, plus a loading dock and ample parking.

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Downtown Street-Level Retail Suites
Downtown Street-Level Retail Suites

45 E Central St, Natick, MA 01760

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4,000 sqft

Flexible suites for retail, office, medical, education, and showroom uses with on-site and nearby parking options.

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Furnished Office Suite
Furnished Office Suite

204a-4 Mechanic St, Natick, MA 01760

$1,000/Mo

Furnished office suite in a modern elevator-served building with ample on-site parking.

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Retail, Medical, Office Space Available
Retail, Medical, Office Space Available

69 East Central Street, Natick, MA 01760

Contact for pricing
8,920 sqft

First floor retail, medical, and office space for lease.

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Flexible Office and Flex Space
Flexible Office and Flex Space

209 West Central St, Natick, MA 01760

$20 SF/Yr

Flexible space available immediately with on-site elevator service and plenty of parking for car-dependent access.

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Natick Office Space for Rent
Natick Office Space for Rent

5 Commonwealth Road, Natick, MA 01760

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2,090 sqft

2,090 SF office space available in Natick, MA.

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Street-Level Retail Storefronts
Street-Level Retail Storefronts

45 E Central St, Natick, MA 01760

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1,966 sqft

Street-level retail suites available in downtown Natick, steps from the MBTA, with on-site surface parking and EV chargers.

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Retail Space with High Ceilings
Retail Space with High Ceilings

1-23 Main St, Natick, MA 01760

Contact for pricing
1,600 sqft

Retail and office spaces in a signature downtown building with 12' to 14' ceilings.

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Renovated Office Building with Elevator
Renovated Office Building with Elevator

4 Mechanic St 200, Natick, MA 01760

$1,500/Mo
0.99 AC lot

Modern office suites with reception area, walkable to downtown.

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Commercial Land with Street-Level Retail
Commercial Land with Street-Level Retail

45 E Central St, Natick, MA 01760

Contact for pricing
2,850 sqft

Flexible space for retail, office, medical, education, and showroom uses steps from the Natick MBTA Station.

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Renovated Three-Story Office Building
Renovated Three-Story Office Building

220 N Main St, Natick, MA 01760

Contact for pricing
3,400 sqft

Renovated office building offers modern upgrades, on-site showers, and ample surface parking across three stories.

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Renovated Office Suites with High Ceilings
Renovated Office Suites with High Ceilings

1-23 Main Street & 2 Summer Street, Natick, MA 01760

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Victorian-era office building with renovated suites, soaring ceilings, and modern systems in downtown Natick’s landmark setting.

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Flexible Office Suite Layouts
Flexible Office Suite Layouts

209 W Central St, Natick, MA 01760

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Available office suites offer private offices, open work areas, conference rooms, and reception spaces with multiple floor plan options.

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Retail Space in Sherwood Plaza
Retail Space in Sherwood Plaza

1276-1290 Worcester St, Natick, MA

Contact for pricing
8,008 sqft 5.01 AC lot

Retail property for lease in a high-traffic shopping center.

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Natick, MA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Natick, MA with 57 listings featured on our commercial real estate exchange. The current inventory includes 521,451 square feet of properties with an estimated lease value of $150.08.

Estimated lease rates for Commercial real estate in Natick, MA begin at $13.60 SF/Yr, with an average of $18.76 SF/Yr and extend to $21 SF/Yr.
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