Lowell, MA Commercial Real Estate for Lease

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81 properties
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Remodeled Specialty Property
Updated: Oct 14
Remodeled Specialty Property

230 Cumberland Road, Lowell, MA 01850

$3,000/Mo
0.11 AC lot
Remodeled commercial space on the first floor
Off‑street parking available
0.11‑acre parcel
Building constructed in 1940
Zoning designation: TTF
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Mixed-Use Building with Gymnasium
Updated: Sep 28
Mixed-Use Building with Gymnasium

8 Kirk St, Lowell, MA 01852

$12 SF/Yr
Large gymnasium or assembly area
Full kitchen
Six additional rooms
B1 zoning
Under construction; listed year built of 2026
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Mixed-Use Property with Storefronts
Mixed-Use Property with Storefronts

408 Suffolk St., Lowell, MA 01854

$15 SF/Yr
6,039 sqft

Planned street-level space includes mechanical systems and bathrooms, with additional fit-out work at the tenant’s expense.

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Multi-Office Professional Suite
Multi-Office Professional Suite

135 Jackson St., Lowell, MA 01852

$13 SF/Yr
7,118 sqft

A flexible office layout combines private work areas, conference rooms, reception, and support space in downtown Lowell.

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Renovated Medical Office Suite
Renovated Medical Office Suite

33 Bartlett St Unit 303, Lowell, MA 01852

$1,900/Mo
1,394 sqft

Third-floor clinical space with exam rooms, reception, kitchenette, restroom, elevator access, and on-campus parking.

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Neighborhood Retail Storefront
Neighborhood Retail Storefront

189 E Merrimack St 2, Lowell, MA 01852

$1,100/Mo
500 sqft

Compact commercial space in an NB-zoned district with strong walkability and public transit access.

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Ground-Floor Creative Office
Ground-Floor Creative Office

201 Canal Street C1, Lowell, MA 01852

$12 SF/Yr
5,000 sqft

An adaptable suite pairs a private entrance with multi-purpose rooms and a dedicated outdoor patio.

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Historic Office Suite with Conference Room
Historic Office Suite with Conference Room

40 Church Street # 200, Lowell, MA 01852

$15 SF/Yr
5,000 sqft

Historic office suite offering seven offices, a large conference room, natural light, and exclusive tenant bathrooms.

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Elevator-Served Office Suite
Elevator-Served Office Suite

27 Prescott St 2, Lowell, MA 01852

$12 SF/Yr
4,000 sqft

A private-entry suite combines dedicated offices, meeting space, and support rooms in a downtown Lowell building.

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Historic Office Suite with Parking
Historic Office Suite with Parking

200-40 Church St, Lowell, MA 01852

$15 SF/Yr
5,100 sqft

Historic office space with natural light, private offices, conference room, and exclusive restrooms plus on-site parking.

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Neighborhood Business Storefront
Neighborhood Business Storefront

189 E Merrimack Street, Unit 2, Lowell, MA 01852

$1,100/Mo
500 sqft

Retail space in Lowell’s NB zoning district at 189 E Merrimack Street.

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Ground-Level Creative Office Space
Ground-Level Creative Office Space

201 Canal Street # C1, Lowell, MA 01852

$12 SF/Yr
5,000 sqft

Flexible commercial suite with a private entrance, canal views, and a walkout patio in a newly constructed mixed-use building.

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Renovated Office Suite with Nine Offices
Renovated Office Suite with Nine Offices

55 Middle Street # 500, Lowell, MA 01852

$16 SF/Yr
4,500 sqft

Recently renovated workspace includes a conference room, kitchenette, and windowed perimeter offices.

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Renovated Office Suite with Windows
Renovated Office Suite with Windows

55 Middle Street, Unit 500, Lowell, MA 01852

$16 SF/Yr
4,500 sqft

Move-in ready suite features an open layout, nine perimeter offices, and a conference room with kitchenette.

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Third-Floor Office Suite
Third-Floor Office Suite

1 Merrimack Street 320/321, Lowell, MA 01852

$750/Mo
422 sqft

Office space includes elevator access beside a parking garage and public transportation service.

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Neighborhood Retail Storefront
Neighborhood Retail Storefront

2-189 E Merrimack St, Lowell, MA 01852

$2,100/Mo
500 sqft

Compact retail space in Lowell’s NB zoning district with visibility and pedestrian activity.

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Renovated Office Suite with Perimeter Offices
Renovated Office Suite with Perimeter Offices

500-55 Middle St, Lowell, MA 01852

$16 SF/Yr
4,500 sqft

Move-in ready suite with open work areas, nine windowed offices, and a conference room in a secured historic building.

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Medical Office Near Lowell General
Medical Office Near Lowell General

33 Bartlett St 303, Lowell, MA 01852

$1,900/Mo
1,380 sqft

Turnkey medical office space connected to Lowell General Hospital.

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Retail Storefront
Retail Storefront

2c-189 E Merrimack St, Lowell, MA 01852

$1,100/Mo
500 sqft

The space is within Lowell’s Neighborhood Business (NB) zoning district.

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First-Floor Flex Space
First-Floor Flex Space

663 Lawrence St Unit 101, Lowell, MA 01852

$10 SF/Yr
10,000 sqft

Adaptable industrial and office space with grade-level garage door access and a layout suited to varied operations.

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Historic Office Suite with Classrooms
Historic Office Suite with Classrooms

401-55 Middle St, Lowell, MA 01852

$16 SF/Yr
3,432 sqft

High ceilings, oversized windows, and secure entry support a bright, functional workspace.

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First-Floor Flex Space with Garage Door
First-Floor Flex Space with Garage Door

663 Lawrence St # 101, Lowell, MA 01852

$10 SF/Yr
10,000 sqft

Versatile first-floor layout combines warehouse, production, storage, and office areas with grade-level garage door access.

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Storefront with Private Room
Storefront with Private Room

297 W 6th St, Lowell, MA 01850

$1,600/Mo
550 sqft

The street-level space has an open layout, a separate room, and a private restroom.

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Ground-Level Office Unit
Ground-Level Office Unit

C1-201 Canal St, Lowell, MA

$12.50 SF/Yr
5,000 sqft

Open-plan commercial suite with private entrance, multipurpose rooms, storage, and a canal-view walkout patio.

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Lowell, MA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Lowell, MA with 81 listings featured on our commercial real estate exchange. The current inventory includes 676,754 square feet of properties with an estimated lease value of $649.33.

Estimated lease rates for Commercial real estate in Lowell, MA begin at $3.10 SF/Yr, with an average of $17.55 SF/Yr and extend to $50.40 SF/Yr.
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