Lowell, MA Commercial Real Estate for Lease

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48 properties
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Standalone Retail Space with Office
Updated: Jun 16, 2025
Standalone Retail Space with Office

183 Appleton St, Lowell, MA 01852

$2,000/Mo
Highly visible, well‑traveled downtown location
Off‑street parking for customers and staff
600 sq ft standalone retail space
Private office area
Employee bathroom
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Historic Office Suite with Conference Room
Updated: May 28
Historic Office Suite with Conference Room

40 Church Street # 200, Lowell, MA 01852

$15 SF/Yr
5,000 sqft
Historic office suite built in 1890 with lots of natural light and high ceilings
Suite includes seven offices, including an executive office and a large conference room
Break area plus exclusive tenant bathrooms
Handicap accessible with parking available in a private lot
LRTA bus stop is across the street
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Ground-Level Creative Office Suite
Ground-Level Creative Office Suite

201 Canal St C1, Lowell, MA 01852

$12 SF/Yr
5,000 sqft

Newly constructed suite with private entrance, open workspace, multi-purpose rooms, and a walkout patio with canal views.

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Downtown Office Suite with Private Entry
Downtown Office Suite with Private Entry

27 Prescott St 2, Lowell, MA 01852

$12 SF/Yr
4,000 sqft

Suite 2 offers a private entrance, reception, multiple offices, conference space, and modern amenities for professional use.

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Historic Office Suite with Parking
Historic Office Suite with Parking

200-40 Church St, Lowell, MA 01852

$15 SF/Yr
5,100 sqft

Historic office space with natural light, private offices, conference room, and exclusive restrooms plus on-site parking.

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Third-Floor Office Suite with Elevator
Third-Floor Office Suite with Elevator

320321-1 Merrimack St, Lowell, MA 01854

$750/Mo
422 sqft

Two-office suite on the third floor with elevator access, well suited for professional services needing downtown presence.

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Third-Floor Office Suite
Third-Floor Office Suite

1 Merrimack Street # 320/321, Lowell, MA 01852

$750/Mo
422 sqft

Office suite with two offices on the 3rd floor and elevator access, totaling 422 sq. ft.

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Flex Space with Grade-Level Access
Flex Space with Grade-Level Access

101-663 Lawrence St, Lowell, MA 01852

$10 SF/Yr
10,000 sqft

First-floor flex space blends warehouse and office areas with convenient grade-level garage door loading for a variety of operations.

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First-Floor Flex Space with Garage Door
First-Floor Flex Space with Garage Door

663 Lawrence St # 101, Lowell, MA 01852

$10 SF/Yr
10,000 sqft

Versatile first-floor layout combines warehouse, production, storage, and office areas with grade-level garage door access.

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Renovated Office Suite with Perimeter Offices
Renovated Office Suite with Perimeter Offices

500-55 Middle St, Lowell, MA 01852

$16 SF/Yr
4,500 sqft

Move-in ready suite with open work areas, nine windowed offices, and a conference room in a secured historic building.

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Renovated Office Suite with Windows
Renovated Office Suite with Windows

55 Middle Street, #500, Lowell, MA 01852

$16 SF/Yr
4,500 sqft

Move-in ready suite features an open layout, nine perimeter offices, and a conference room with kitchenette.

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First-Floor Flex Office Space
First-Floor Flex Office Space

595 Pawtucket Blvd #A, Lowell, MA 01854

$18 SF/Yr
1,700 sqft

First-floor suite with flexible layout, elevator service, and handicap accessibility in a highly visible commercial setting.

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Second-Floor Office Suite
Second-Floor Office Suite

1201 Westford St, #U-1, Lowell, MA 01851

$2,400/Mo
2,326 sqft

Move-in-ready second-floor office suite with five private offices, open work area, dedicated restrooms, and on-site parking.

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Retail Storefront with Off-Street Parking
Retail Storefront with Off-Street Parking

113b-115 Chelmsford St, Lowell, MA 01851

$1,100/Mo
540 sqft

Storefront retail space with off-street parking and minisplit system on a high-traffic Lowell corridor.

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First-Floor Private Office Suite
First-Floor Private Office Suite

463 Merrimack # 109, Lowell, MA 01852

$495/Mo
144 sqft

First-floor private office suite with reception, conference room, break/copy area, and restrooms in a shared setting.

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Office Suite with Classroom Space
Office Suite with Classroom Space

55 Middle Street, Unit 401, Lowell, MA 01852

$20 SF/Yr
3,432 sqft

Fourth-floor office suite includes classroom-style space and an adjoining lounge with abundant natural light.

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Historic Office Suite with Parking
Historic Office Suite with Parking

40 Church Street, Unit 200, Lowell, MA 01852

$15 SF/Yr
5,000 sqft

Unit 200 features seven private offices, a large conference room, and exclusive tenant restrooms with on-site private parking.

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Mixed-Use Commercial Space Available
Mixed-Use Commercial Space Available

225 Stedman Street #13, Lowell, MA 01851

$2,800/Mo
1,980 sqft

Two-story mixed-use space with office and light industrial areas.

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Third-Floor Medical Office Suite
Third-Floor Medical Office Suite

33 Bartlett Street, #303, Lowell, MA 01852

$2,500/Mo
1,394 sqft

Turnkey suite with exam rooms and an in-suite restroom, positioned within a medical office building connected to Lowell General Hospital.

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First-Floor Private Office Suite
First-Floor Private Office Suite

106-463 Merrimack St, Lowell, MA 01852

$495/Mo
144 sqft

First-floor private office includes reception, shared conference room, kitchen/break/copy area, and rest rooms.

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Elevator-Served Medical Office Suite
Elevator-Served Medical Office Suite

847 Rogers St, Lowell, MA 01852

$14 SF/Yr
4,344 sqft

Second-floor medical office suite with elevator access, reception, private perimeter offices, and an open cubicle/workstation area.

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Historic Downtown Office Space Available
Historic Downtown Office Space Available

40-44 Church St, Lowell, MA

$18 SF/Yr
5,000 sqft

Handicap accessible office space in historic downtown Lowell building.

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Medical Office Suite with Exam Rooms
Medical Office Suite with Exam Rooms

21 George St, #303, Lowell, MA 01852

$2,500/Mo

Suite includes five exam/treatment rooms with sinks and plumbing, plus a waiting area and multiple support work areas.

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Renovated Retail Office Flex Suite
Renovated Retail Office Flex Suite

31 First Street Boulevard, Unit Retail, Lowell, MA 01850

$13 SF/Yr
25,730 sqft

First-floor suite offers storefront exposure, open workspace, private offices, and conference room with on-site parking.

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Lowell, MA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Lowell, MA with 48 listings featured on our commercial real estate exchange. The current inventory includes 115,778 square feet of properties with an estimated lease value of $513.99 /Mo.

Estimated lease rates for Commercial real estate in Lowell, MA begin at $10 SF/Yr, with an average of $19.04 SF/Yr and extend to $41.25 SF/Yr.
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