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    Hampshire County, MA Commercial Real Estate for Lease

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    121 properties
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    Adaptive Retail Space with Subdivision
    Updated: Jul 24
    Adaptive Retail Space with Subdivision

    61-63 Cowls Road, Amherst, MA 01002

    $24 SF/Yr
    4,038 sqft
    4,038 SF retail space available for lease in The Mill District
    Space can be subdivided to support multiple retail concepts
    Located about 1/2 mile from UMass Amherst
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    Second-Floor Office Suite
    Updated: Jun 11
    Second-Floor Office Suite

    304 Pleasant St, Northampton, MA 01060

    $16 SF/Yr
    3,600 sqft
    Vacant 3,600 SF second‑level office suite with full‑floor, single‑tenant occupancy
    Located at 300 Pleasant Street in Northampton, MA 01060
    Flexible layout suitable for professional, administrative, medical, or office uses
    Lease rate is $4,800 per month plus utilities ($16/SF annually)
    Immediate availability for occupancy
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    Medical Office Suites with Parking
    Medical Office Suites with Parking

    264 Elm St B&c, Northampton, MA 01060

    $22 SF/Yr
    1,285 sqft

    First- and second-floor medical office space with ADA access and over 40 parking spaces.

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    Retail Space with Display Windows
    Retail Space with Display Windows

    158 Main St, Northampton, MA 01060

    $4,000/Mo
    2,400 sqft

    White-box storefront with basement storage, climate control, and the option to divide the space between two compatible businesses.

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    Contemporary Office Unit
    Contemporary Office Unit

    318 Newton St Unit 2, South Hadley, MA 01075

    $700/Mo
    500 sqft

    Updated interior with flexible office or service-oriented layout opposite a local high school.

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    Renovated Lower-Level Office Suite
    Renovated Lower-Level Office Suite

    41 Main St B1, Northampton, MA 01062

    $1,500/Mo
    1,300 sqft

    Renovated general business office with private offices, conference room, and kitchenette; utilities and dumpster use paid by tenant.

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    Turnkey Office Space
    Turnkey Office Space

    32 Industrial Dr E, Northampton, MA 01060

    $17 SF/Yr
    7,000 sqft

    Turnkey second-floor office space with shared conference rooms, kitchen/break room, and ample parking included.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    7 N Pleasant Street 2c, Amherst, MA 01002

    $2,700/Mo
    1,050 sqft

    Four private offices and a generous reception area create a practical professional setting.

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    Industrial Warehouse with Overhead Door
    Industrial Warehouse with Overhead Door

    6 Industrial Pkwy, Easthampton, MA 01027

    $7 SF/Yr
    10,700 sqft

    10,700 SF industrial building includes 22-foot clear height, radiant heat, air conditioning, and a single overhead bay door.

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    Open-Plan Storefront Space
    Open-Plan Storefront Space

    32 Union St., Easthampton, MA 01027

    $18 SF/Yr
    8,515 sqft

    Vacant commercial space with street-facing windows, on-site parking, and zoning designated DB.

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    Retail Takeout Space with Windows
    Retail Takeout Space with Windows

    D-22 West St, West Hatfield, MA

    $750/Mo
    300 sqft

    Compact retail space includes two front-facing service windows, a private restroom, and ample customer parking.

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    Accessible Office Unit
    Accessible Office Unit

    101-10-123 Union St, Easthampton, MA 01027

    $450/Mo
    145 sqft

    Lease includes utilities, Wi-Fi, parking, and use of shared conference and kitchenette areas.

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    Downtown Office Suite
    Downtown Office Suite

    48 N Pleasant Street # 301, Amherst, MA 01002

    $5,770/Mo
    2,473 sqft

    Office suite with reception, private offices, conference room, kitchenette, and open bullpen; utilities included.

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    Retail/Office Suite
    Retail/Office Suite

    131 Main St # 106-107, Hatfield, MA 01038

    $1,400/Mo
    1,000 sqft

    Flexible 1,000 SF suite available March 1, 2026 with on-site parking at 131 Main St.

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    Main Street Commercial Spaces Available
    Main Street Commercial Spaces Available

    78 Main St, Northampton, MA 01060

    $20 SF/Yr
    2,638 sqft

    Commercial spaces for rent on Main Street, Northampton, MA.

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    Office Unit with Elevator Access
    Office Unit with Elevator Access

    3-100 Main St, Northampton, MA

    $5,000/Mo
    2,500 sqft

    Third-floor office space offers private rooms, meeting space, a kitchenette, restrooms, and flexible open workspace.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    7 N Pleasant Street # 2c, Amherst, MA 01002

    $2,700/Mo
    1,050 sqft

    Four private offices, reception space, restrooms, and elevator-accessible entry support a professional workplace layout.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    234236-241 King St, Northampton, MA 01060

    $1,975/Mo
    900 sqft

    Second-floor suite with three private offices, conference room, waiting area, and private restroom for office tenants.

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    First-Floor Office Unit
    First-Floor Office Unit

    30 Boltwood Walk # 2, Amherst, MA 01002

    $600/Mo
    145 sqft

    Office suite with shared business amenities and accessible restroom facilities.

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    Florence Office Space For Rent
    Florence Office Space For Rent

    41 Main St B2, Northampton, MA 01062

    $750/Mo
    900 sqft

    900 SF office space in central Florence.

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    Charming Office Space in Northampton
    Charming Office Space in Northampton

    46 Main St Front, Northampton, MA 01060

    $650/Mo
    419 sqft

    Unique office space with exposed brick, high ceilings, and natural light.

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    Lower Level Office Suite
    Lower Level Office Suite

    B2-41 Main St, Northampton, MA

    $750/Mo
    900 sqft

    Lower level suite with three private offices and open workspace, zoned General Business.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    2c-7 N Pleasant St, Amherst, MA 01002

    $2,700/Mo
    1,050 sqft

    Second-floor office suite with a front lobby, waiting/reception area, and four private offices in an accessible building.

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    Renovated Office Suite with Kitchenette
    Renovated Office Suite with Kitchenette

    B1-41 Main St, Northampton, MA

    $1,500/Mo
    1,300 sqft

    Lower-level office suite offers four private offices, conference space, open workspace, and a kitchenette.

    View details

    Hampshire County, MA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Hampshire County, MA with 121 listings featured on our commercial real estate exchange. The current inventory includes 794,474 square feet of properties with an estimated lease value of $1,973.

    Estimated lease rates for Commercial real estate in Hampshire County, MA begin at $7 SF/Yr, with an average of $26.31 SF/Yr and extend to $150 SF/Yr.
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