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    Middlesex County, MA Commercial Real Estate for Sale

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    Boston, MA Worcester, MA Springfield, MA
    632 results
    Mixed-Use Property in Lowell, MA
    $750,000
    3,774 SF

    Mixed-Use Property in Lowell, MA

    525 Chelmsford St, Lowell, MA 01851

    Mixed-use property with commercial space and residential unit.

    • Mixed‑use property featuring commercial space and a large residential unit.
    • Two retail storefronts boast high street visibility and traffic on Chelmsford Street.
    • Off‑street parking for 10+ vehicles plus a carport.
    • Spacious 4‑5 bedroom residential unit with a flexible floor plan.
    • Unfinished 2nd floor offers expansion potential for commercial space.
    Updated: Dec 7, 2025
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    Hudson Development Opportunity: 15+ Acres
    $594,900
    15.39 Acres

    Hudson Development Opportunity: 15+ Acres

    Washington Street, Hudson, MA 01749

    15.39 acres in Hudson, near major retailers, convenient highway access.

    • Prime 15.39‑acre development opportunity in MetroWest.
    • Convenient access to I‑495 and I‑290 via Route 85 Connector.
    • Located behind established Pub 99 retail node.
    • Surrounded by major retailers including Walmart, CVS, Walgreens, and Stop & Shop.
    • Access via recorded 50‑foot Right‑of‑Way from Washington Street.
    Updated: May 15
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    Somerville Mixed-Use Building For Sale
    $1,699,000
    3,115 SF

    Somerville Mixed-Use Building For Sale

    Mixed-use building with residential and commercial units in Somerville.

    148 Pearl, Somerville, MA 02145
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    Spacious Office Condo in Medford
    $694,000
    3,000 SF

    Spacious Office Condo in Medford

    Expansive professional office condo in a high-visibility Medford location.

    92 High Street #T31, Medford, MA 2155
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    Groton Commercial Development Opportunity
    $825,000
    2.80 Acres

    Groton Commercial Development Opportunity

    Prime land parcel in Groton, MA, for diverse development.

    797 Boston Rd, Groton, MA 01450
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    Framingham Automotive Repair Shop For Sale
    $600,000
    4,800 SF

    Framingham Automotive Repair Shop For Sale

    Established automotive repair shop with loyal customer base and equipment.

    150 Speen Street, Framingham, MA 1701
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    Mixed-Use Building Near UMASS Lowell
    $1,300,000
    7,178 SF

    Mixed-Use Building Near UMASS Lowell

    Five-unit mixed-use building with retail space and residential units.

    169-171 Salem St, Lowell, MA 01854
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    Newton Mixed-Use Development Opportunity
    $6,250,000
    14,485 SF

    Newton Mixed-Use Development Opportunity

    Mixed-use property near transit with development potential in Newton, MA.

    823-833 Washington Street, Newton, MA 2460
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    Renovated Commercial Condo For Sale
    $425,000
    2,400 SF

    Renovated Commercial Condo For Sale

    Two-level commercial condo with flexible zoning and ample parking.

    1794 Bridge St #4, Dracut, MA 1826
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    Belmont Mixed-Use Investment Opportunity
    $995,000
    1,840 SF

    Belmont Mixed-Use Investment Opportunity

    Versatile 1,840 SF building in Belmont, MA with mixed-use potential.

    113 Belmont, Belmont, MA 2478
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    Turnkey Commercial Kitchen For Sale
    $849,000

    Turnkey Commercial Kitchen For Sale

    Well-equipped commercial kitchen suitable for various food service operations.

    39 Emerson Rd #108, Waltham, MA 2451
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    Renovated Office Building in Wakefield
    $1,695,000
    2,700 SF

    Renovated Office Building in Wakefield

    Turn-key office building with recent renovations and expansion.

    45 Albion St, Wakefield, MA 1880
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    Prime Commercial Land on Route 3A
    $500,000
    1.00 Acre

    Prime Commercial Land on Route 3A

    1.0 acre B1-zoned commercial parcel with high-visibility frontage.

    114 Middlesex Road, Tyngsborough, MA 1879
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    Spacious Medford Square Office Condo
    $749,900
    3,357 SF

    Spacious Medford Square Office Condo

    Versatile 3,357 sq ft office condo in Medford Square.

    92 High Street #T31, Medford, MA 2155
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    Renovated Commercial Space Near T-Station
    $550,000
    1,048 SF

    Renovated Commercial Space Near T-Station

    1,048 SF renovated commercial space across from Oak Grove T-station.

    1 Glenwood St 6, Malden, MA 2148
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    Waltham Medical Commercial Condo Unit
    $449,000

    Waltham Medical Commercial Condo Unit

    Medical commercial condo unit in a prime, convenient location.

    20 Hope Avenue #208, Waltham, MA 2453
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    Groton Retail, Office, Restaurant Space
    $499,000
    3,234 SF

    Groton Retail, Office, Restaurant Space

    Raw space in mixed-use complex, ready for buildout.

    134 Main St #LL, Groton, MA 1450
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    West Newton Retail Opportunity
    $2,700,000
    5,000 SF

    West Newton Retail Opportunity

    Retail asset near West Newton Cinema with redevelopment potential.

    1298-1308 Washington Street, Newton, MA 2465
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    Watertown Restaurant Opportunity For Sale
    $649,000

    Watertown Restaurant Opportunity For Sale

    Free-standing vacant restaurant with FF&E near Watertown Mall.

    71-73 Elm St, Watertown, MA 2472
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    Renovated Commercial Condo in Winchester
    $400,000

    Renovated Commercial Condo in Winchester

    Turnkey commercial condo in downtown Winchester near amenities and transportation.

    63 Shore Road #14, Winchester, MA 1890
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    Historic Building in Reading, MA
    $1,495,000
    7,041 SF

    Historic Building in Reading, MA

    7,041 SF building suitable for special purpose or redevelopment.

    32 Lowell St, Reading, MA 1867
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    Renovated Commercial Space Near T-Station
    $550,000
    1,048 SF

    Renovated Commercial Space Near T-Station

    1,048 SF renovated commercial space across from Oak Grove T-station.

    1 Glenwood St #6, Malden, MA 2148
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    Medical Office Condo For Sale
    $529,000

    Medical Office Condo For Sale

    Medical office condominium for sale in a convenient location.

    20 Hope Avenue #207, Waltham, MA 2453
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    Inman Square Retail Opportunity
    $2,950,000
    3,820 SF

    Inman Square Retail Opportunity

    Prime Somerville/Cambridge location with two retail units and parking.

    70 Beacon, Somerville, MA 2143
    View details

    Middlesex County, MA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 5000+ commercial real estate for sale in Middlesex County, MA, showcased through 632 active listings on our real estate platform. These investment opportunities span a total of 2,146,039 square feet of properties for sale, with an estimated market value of $545,815,791.

    Sale prices for business properties in Middlesex County, MA start at $60,000, averaging $1,901,797, and reaching up to $9,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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