Des Moines, IA Commercial Real Estate for Lease

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Retail Space in Des Moines
Retail Space in Des Moines

5101 SE 14th St, Des Moines, IA 50320

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243,000 sqft

Outparcel available in a high-traffic shopping center.

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Premier Downtown Des Moines Office
Premier Downtown Des Moines Office

801 Grand Ave, Des Moines, IA 50309

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Premier office building in the heart of Downtown Des Moines.

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Based on your search, we've compiled 484 Potential Opportunities for your consideration. Besides 242 Active listings in Des Moines, IA, we suggest exploring alternatives. Consider Similar 238 Spaces for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Office Space on Hickman Road
Office Space on Hickman Road

7900 Hickman Road, Windsor Heights, IA 50324

$12.50 SF/Yr
14,000 sqft

Office space for rent with excellent location and amenities.

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Office End Cap with Reception
Office End Cap with Reception

3881-3921 121st St, Urbandale, IA 50323

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1,653 sqft

End cap office suite features reception, bullpen workspace, conference room, two private offices, and kitchenette.

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Medical Office Space Available
Medical Office Space Available

7180 Hickman Road, Windsor Heights, IA 50324

$9 SF/Yr

Former orthodontics office with operatories, lab, and private offices.

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Class A Flex Space Available
Class A Flex Space Available

4651 121st St, Urbandale, IA 50323

Contact for pricing
215,000 sqft

215,000 SF Class A flex space in Urbandale, Iowa.

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Similar Spaces for Sale in Des Moines, IA

Consider Similar Space for Sale. We found 238 Spaces matching your search parameters.

Standalone One-Story Office Building
Standalone One-Story Office Building

2721 SW 30th St, Des Moines, IA 50321

$590,000
3,868 sqft 0.63 AC lot

Flexible professional layout with private offices, conference space, kitchen, and multiple restrooms.

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Heavy Industrial Warehouse with Office
Heavy Industrial Warehouse with Office

4485 Northeast 22nd Street, Des Moines, IA 50313

$2,150,000
10,500 sqft 4.65 AC lot

Warehouse with heavy industrial zoning, finished office space, and multiple loading doors for practical industrial operations.

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Mixed-Use Flex Space with Warehouse
Mixed-Use Flex Space with Warehouse

2401 Hickman Road, Des Moines, IA 50310

$1,335,000
15,547 sqft

Mixed-use commercial space combines warehouse, garage, office, training, breakroom, and bathroom areas.

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Office Building with Finished Basement
Office Building with Finished Basement

4001 Ingersoll Avenue, Des Moines, IA 50312

$576,036
4,372 sqft

Mid-century office property with a brick-and-concrete exterior, finished lower level, and on-site parking.

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Automotive Property With Attached Shop
Automotive Property With Attached Shop

4106 14th, Des Moines, IA 50313

$749,000
2,568 sqft

Finished office, gated access, and a surfaced lot support automotive uses.

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Animal Medical Office
Animal Medical Office

4520 Merle Hay Rd, Des Moines, IA 50310

$625,000
2,250 sqft 0.48 AC lot

Existing veterinary clinic within a Highway Commercial District property in Des Moines.

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Turnkey Bank in Thriving District
Turnkey Bank in Thriving District

2805 Beaver Ave |, Des Moines, IA 50310

$1,510,000
5,000 sqft 0.85 AC lot

Spacious bank building with redevelopment potential in a walkable neighborhood.

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Day Care Center with Martial Arts Studio
Day Care Center with Martial Arts Studio

606 E Army Post Rd, Des Moines, IA 50315

$1,600,000
16,160 sqft

Established child care and martial arts operations occupy a well-maintained commercial facility with six AC units and furnaces.

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Industrial Flex Building with Crane
Industrial Flex Building with Crane

700 New York Avenue, Des Moines, IA 50313

$4,200,000
36,430 sqft 2.06 AC lot

Renovated commercial facility with docks, drive-in access, crane system, and secured outdoor storage.

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Church and Community Facility
Church and Community Facility

3023 29th Street, Des Moines, IA 50317

$474,900
4,282 sqft

Adaptable civic-use building with a large gathering room, separate restrooms, and dedicated on-site parking.

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Flex Space with Warehouse
Flex Space with Warehouse

2401 Hickman Road, Des Moines, IA 50310

$1,335,000
1.86 AC lot

Mixed-use commercial facility combining warehouse, office, training, breakroom, garage, and restroom areas.

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Office Building with 2025 Roof HVAC
Office Building with 2025 Roof HVAC

2301 Rittenhouse Street, Des Moines, IA 50321

$3,275,000
29,408 sqft

Recent roof and HVAC replacement in 2025 support this office building near the Fleur Drive corridor.

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Retail Property in Capitol East
Retail Property in Capitol East

521 East 14th Street, Des Moines, IA 50316

$725,000
3,168 sqft

Retail space with high visibility in Capitol East neighborhood.

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Freestanding Retail Building
Freestanding Retail Building

3400 East 25th Street, Des Moines, IA 50317

$384,024
1,018 sqft 1.70 AC lot

Standalone retail property positioned on a 1.7-acre parcel in Des Moines.

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Drive-Through Restaurant with Kitchen Equipment
Drive-Through Restaurant with Kitchen Equipment

5405 Douglas Ave, Des Moines, IA 50310

$699,990
2,354 sqft

Existing food-service improvements support restaurant, coffee, or specialty retail use along the Douglas Avenue corridor.

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Retail Property in Des Moines
Retail Property in Des Moines

6200 Southeast 14th Street, Des Moines, IA 50320

$3,150,000
14,560 sqft

Single-tenant retail property operating as a Walgreens.

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Renovated Storefront Property
Renovated Storefront Property

6007 Southwest 9th Street, Des Moines, IA 50315

$345,000
2,595 sqft 0.55 AC lot

Single-story commercial building with RX1 zoning and improvements completed in 2022.

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Freestanding Storefront Building
Freestanding Storefront Building

Des Moines, IA 50312

$650,000
1,890 sqft

Single-tenant retail asset with MX2 zoning and an occupied lease.

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Des Moines Industrial Investment Property
Des Moines Industrial Investment Property

1631 2nd Ave, Des Moines, IA 50314

$1,400,000
9,409 sqft

Fully occupied industrial property with long-term tenant in Des Moines.

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Office Units with Retail Space
Office Units with Retail Space

6307 Hickman Road, Des Moines, IA 50322

$211,213
2,880 sqft

Office and retail space is positioned along Hickman Road near Interstate 80/35 access.

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Development Site on East 14th
Development Site on East 14th

3810 East 14th Street, Des Moines, IA 50313

$529,000
1 sqft 1.36 AC lot

1.364 acres for office, retail, or multi-family development.

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Des Moines Office Building For Sale
Des Moines Office Building For Sale

2100 Fleur Drive, Des Moines, IA 50321

$2,900,000
29,289 sqft

Professional office space with great views and easy airport access.

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