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Des Moines, IA Office Spaces for Lease

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Urbandale, IA Windsor Heights, IA Pleasant Hill, IA West Des Moines, IA Ankeny, IA Clive, IA Johnston, IA Elkhart, IA
86 properties
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Fully Serviced Workspace Options at IA, Des Moines - Grand Ave. Contact us today to book a tour!
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Flexible Workspace Solutions at Hub Tower. Contact us today to book a tour!
Updated: Feb 19
Flexible Workspace Solutions at Hub Tower. Contact us today to book a tour!

699 Walnut St, Unit 400, Des Moines, IA 50309

16 available spaces from 11 to 2,087 sqft
$109-$7,950/Mo per office
Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
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Flex Space with High Ceilings
Updated: Sep 2
Flex Space with High Ceilings

1536 E Army Post Rd, Des Moines, IA 50320

$7 SF/Yr
14,198 sqft
14,198 square feet of customizable flex space
Supports office or industrial use
High ceilings and expansive floor plan
Ample parking available
Access to major transportation routes
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Creative Loft Office Space
Creative Loft Office Space

506 3rd Street, Des Moines, IA 50309

$12 SF/Yr
4,836 sqft

Third-floor office suite in a 1916 brick building with loft/creative design and on-site parking.

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Historic Second-Floor Office Units
Historic Second-Floor Office Units

319 7th Street, Des Moines, IA 50309

$14 SF/Yr
6,000 sqft

Office space in a mixed-use historic building with sidewalk access and covered parking availability.

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Medical Office Building with Parking
Medical Office Building with Parking

1530 East Euclid Avenue, Des Moines, IA 50313

$15 SF/Yr
9,608 sqft 1.07 AC lot

Well-maintained medical office building with private exam rooms, lab space, and on-site parking for medical or office use.

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Medical Office Building
Medical Office Building

2459 East Euclid Avenue, Des Moines, IA 50317

$20 SF/Yr
6,240 sqft 0.53 AC lot

Well-maintained medical office building with on-site parking and space available up to 6,240 square feet.

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West Mall Inline Retail Spaces
West Mall Inline Retail Spaces

1111 East Army Post Road, Des Moines, IA 50315

$17.50 SF/Yr
15,665 sqft

Flexible inline retail space in a redeveloped mixed-use center, including a 45,000 SF former theatre building.

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Flex Space with Office Area
Flex Space with Office Area

1800 Dixon St, Des Moines, IA 50316

$8 SF/Yr
7,200 sqft

Flexible warehouse and office configuration with interstate access and ample parking.

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Two-Story Office Building For Sale
Two-Story Office Building For Sale

3161 Southeast 22nd Street, Des Moines, IA 50320

$16 SF/Yr
1,872 sqft

1,872 SF office building with partially finished basement.

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Des Moines Office Space Available
Des Moines Office Space Available

601 East Locust Street, Des Moines, IA 50309

$22 SF/Yr
2,844 sqft

Office space for rent with convenient parking and highway access.

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Office Space Near Sculpture Park
Office Space Near Sculpture Park

1300 Walnut Street, Des Moines, IA 50309

$12 SF/Yr
6,401 sqft

Office space for rent near downtown Des Moines attractions.

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Industrial Space with Dock Doors
Industrial Space with Dock Doors

10400 Hickman Road, Des Moines, IA 50325

$6 SF/Yr
20,000 sqft

20,000 SF industrial space with office and dock doors.

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Historic Office Building in Des Moines
Historic Office Building in Des Moines

1420 Locust Street, Des Moines, IA 50309

$17 SF/Yr
7,689 sqft

Two-story office building with unique architecture and high-end finishes.

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Historic Office Units
Historic Office Units

301 East Court Avenue, Des Moines, IA 50309

$13.50 SF/Yr
26,585 sqft

Flexible office and studio units occupy a mixed-use property with convenient interstate access.

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Office Space Near Krause Gateway
Office Space Near Krause Gateway

1533 Linden Street, Des Moines, IA 50309

$12 SF/Yr
2,700 sqft

Office space for lease in a convenient location.

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Downtown Des Moines Office Space
Downtown Des Moines Office Space

500 Southwest 7th Street, Des Moines, IA 50309

$19.25 SF/Yr
14,360 sqft

Three-story office building in vibrant Riverpoint district with parking.

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Des Moines Office Space Available
Des Moines Office Space Available

2501 Grand Ave, Des Moines, IA 50312

$12 SF/Yr
2,646 sqft

Office units for rent in Des Moines, Iowa.

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Retail/Office Space in Mixed-Use Building
Retail/Office Space in Mixed-Use Building

210 Southwest 11th Street, Des Moines, IA 50309

$18 SF/Yr
4,539 sqft

Trendy retail or office space in a modern urban neighborhood.

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Creative Space with Exterior Signage
Creative Space with Exterior Signage

516 3rd Street, Des Moines, IA 50309

Contact for pricing
5,795 sqft

Historic commercial space offers onsite parking, building signage, and convenient access to I-235.

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Office Building Near Recreation
Office Building Near Recreation

3161 SE 22nd St, Des Moines, IA 50320

Contact for pricing
3,096 sqft

Office property with RX1 zoning and recently replaced furnace, air conditioning, and water heater systems.

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East Village Contemporary Office Space
East Village Contemporary Office Space

505 East Grand Avenue, Des Moines, IA 50309

$14 SF/Yr
10,401 sqft

Modern 10,401 SF office in vibrant urban environment.

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Office Space with Skywalk Parking
Office Space with Skywalk Parking

665 Grand Ave, Des Moines, IA 50309

Contact for pricing
6,664 sqft

Lease opportunity includes furniture, building signage potential, and parking reached through a connected skywalk.

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Flex Space with Office and Warehouse
Flex Space with Office and Warehouse

1427 E Pleasant View Dr, Des Moines, IA 50320

Contact for pricing
7,300 sqft 1.52 AC lot

Commercial property offers a flexible office-and-warehouse configuration across five parcels.

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Stratford Commons Office Park Space
Stratford Commons Office Park Space

12035 University Ave., Des Moines, IA 50325

$20.50 SF/Yr
12,645 sqft

Office space with private entrance, granite floors, and cherry woodwork.

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Des Moines, IA Office Spaces Lease Rates & Market Statistics

Browse 86 Office Spaces for lease in Des Moines, IA on Realmo, a commercial real estate marketplace serving the Des Moines area. The current inventory totals 1,290,875 square feet of properties — an average of ~15,000 SF per listing.

Office Spaces lease rates in Des Moines range from $6 SF/Yr at the entry level to $23.50 SF/Yr at the top of the market, averaging $15.16 SF/Yr. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $15.16 SF/Yr, the local average runs 19% below Iowa's state average of $18.72 SF/Yr.

Des Moines accounts for 43% of the 202 office spaces currently available across Polk County, where nearby markets include West Des Moines and Urbandale. By space type, the market includes 45 office units, 33 office buildings and 9 creative space listings — creative space options typically offer the lowest entry point, while office buildings command the highest rates.

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