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    Des Moines, IA Medical Office Space for Sale

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    Ankeny, IA Dubuque, IA Cedar Rapids, IA
    Des Moines Office Building For Sale
    $389,000
    2,152 SF

    Des Moines Office Building For Sale

    3811 38th St., Des Moines, IA 50310

    Two-story office building near Des Moines VA Medical Center.

    • Excellent visibility and convenient access due to its location near Douglas Avenue.
    • Well‑located near the Des Moines VA Medical Center.
    • On‑site parking for 12+ cars.
    • RX1 Mixed Use District zoning allows for flexible usage.
    • Full‑size kitchen and 3/4 bathroom on the main level.
    Updated: Nov 21, 2025
    View details
    Former Dentist Office with Space
    Contact for pricing
    7,260 SF

    Former Dentist Office with Space

    4919 Douglas Avenue, Des Moines, IA 50310

    First and second floor office spaces available for lease.

    • Large first‑floor space: Nearly 2000 sqft, suitable for various uses.
    • Additional second‑floor space: 550 sqft with 3 office rooms.
    • Two second‑floor offices include private restrooms.
    • Ample Parking
    • MX1 Zoning
    Updated: Jan 27
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    Medical Office Near Mercy Campus
    $460,000

    Medical Office Near Mercy Campus

    Medical office space for sale near Mercy Medical Campus.

    303 University Avenue, Des Moines, IA 50314
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    Medical Office Building For Sale
    $460,000
    3,623 SF

    Medical Office Building For Sale

    Single-story medical office building with University Avenue frontage.

    303 University Avenue, Des Moines, IA 50314
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    Luxury Mixed-Use Community in Des Moines
    Contact for pricing
    16,901 SF

    Luxury Mixed-Use Community in Des Moines

    42-unit mixed-use property with apartments, townhomes, and medical office.

    4362 Hickman Road, Des Moines, IA 50310
    View details
    Based on your search, we've compiled 110 Potential Opportunities for your consideration. Besides 5 Active listings in Des Moines, IA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 97 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Former Dental Office with Theater
    $1,500,000
    5,114 SF

    Former Dental Office with Theater

    Versatile Urbandale property with unique features and expansion potential.

    8501 Plum Dr, Urbandale, IA
    View details
    New Construction Office Building
    Contact for pricing
    9,847 SF

    New Construction Office Building

    Single-story building in Vintage Business Park, ideal for office tenants.

    1930 SW Magazine Rd, Ankeny, IA
    View details
    Standalone Office Building For Sale
    Contact for pricing
    3,960 SF

    Standalone Office Building For Sale

    3,960 SF office building with quick Interstate 35 access.

    6901 Hickman Rd, Urbandale, IA
    View details
    Ankeny Boulevard Medical/Professional Office
    Contact for pricing
    3,825 SF

    Ankeny Boulevard Medical/Professional Office

    Former physical therapy clinic suitable for medical or professional services.

    2675 N Ankeny Blvd, Ankeny, IA
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Nebraska City
    $295,000
    80,046 SF

    Commercial Land in Nebraska City

    1.84 acre commercial land suitable for various development projects.

    17-8-14 LOT C-2 ARBOR VILLAGE ADDITION, Nebraska City, NE 68410
    View details
    Highway Frontage Commercial Land Parcel
    $75,000
    2.90 Acres

    Highway Frontage Commercial Land Parcel

    2.9 acre commercial land parcel with highway frontage.

    Xxx State Highway 56, Le Roy, MN 55951
    View details
    Dubuque Commercial Development Site
    $600,000
    2.93 Acres

    Dubuque Commercial Development Site

    Prime commercial land with high visibility and highway frontage.

    6501 Boulder Brook Court, Dubuque, IA 52003
    View details
    Mankato Commercial Land For Sale
    $165,000
    1.08 Acres

    Mankato Commercial Land For Sale

    Accessible 1.08-acre lot suitable for various business types.

    1763 Bassett Drive, Mankato, MN 56001
    View details

    Explore Off-Market Properties in Des Moines, IA

    Consider similar Off-Market properties in Des Moines, IA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1330 2nd Ave

    1330 2nd Ave

    MEDICAL BUILDING • 2,394 SF
    Value Estimation by Request
    1330 2nd Ave, Des Moines, IA 50314-3401
    View details
    2505 Wedgewood Rd

    2505 Wedgewood Rd

    MEDICAL BUILDING • 2,640 SF
    Value Estimation by Request
    2505 Wedgewood Rd, Des Moines, IA 50317-6027
    View details
    1201 Pennsylvania Ave

    1201 Pennsylvania Ave

    MEDICAL BUILDING • 6,626 SF
    Value Estimation
    $4,630,000
    1201 Pennsylvania Ave, Des Moines, IA 50316-2339
    View details
    619 Euclid Ave

    619 Euclid Ave

    MEDICAL BUILDING • 2,276 SF
    Value Estimation by Request
    619 Euclid Ave, Des Moines, IA 50313-4111
    View details
    2525 Euclid Ave

    2525 Euclid Ave

    MEDICAL BUILDING • 7,687 SF
    Value Estimation by Request
    2525 Euclid Ave, Des Moines, IA 50317-6045
    View details
    4401 9th St

    4401 9th St

    MEDICAL BUILDING • 4,374 SF
    Value Estimation by Request
    4401 9th St, Des Moines, IA 50315-3909
    View details
    2940 Ingersoll Ave

    2940 Ingersoll Ave

    MEDICAL BUILDING • 5,332 SF
    Value Estimation
    $805,000
    2940 Ingersoll Ave, Des Moines, IA 50312-4015
    View details
    850 Dickman Rd

    850 Dickman Rd

    MEDICAL BUILDING • 25,764 SF
    Value Estimation
    $8,420,000
    850 Dickman Rd, Des Moines, IA 50315
    View details
    717 Lyon St

    717 Lyon St

    MEDICAL BUILDING • 14,380 SF
    Value Estimation
    $2,610,000
    717 Lyon St, Des Moines, IA 50309-5458
    View details
    3836 Beaver Ave

    3836 Beaver Ave

    MEDICAL BUILDING • 2,413 SF
    Value Estimation by Request
    3836 Beaver Ave, Des Moines, IA 50310-3633
    View details
    4919 Douglas Ave

    4919 Douglas Ave

    MEDICAL BUILDING • 8,460 SF
    Value Estimation by Request
    4919 Douglas Ave, Des Moines, IA 50310-2775
    View details
    621 Euclid Ave

    621 Euclid Ave

    MEDICAL BUILDING • 3,438 SF
    Value Estimation by Request
    621 Euclid Ave, Des Moines, IA 50313-4111
    View details
    4730 9th St

    4730 9th St

    MEDICAL BUILDING • 4,160 SF
    Value Estimation by Request
    4730 9th St, Des Moines, IA 50315-3973
    View details
    95 University Ave

    95 University Ave

    MEDICAL BUILDING • 39,672 SF
    Value Estimation
    $2,925,000
    95 University Ave, Des Moines, IA 50314-3120
    View details
    600 Euclid Ave

    600 Euclid Ave

    MEDICAL BUILDING • 2,880 SF
    Value Estimation by Request
    600 Euclid Ave, Des Moines, IA 50313-4557
    View details
    4020 Merle Hay Rd

    4020 Merle Hay Rd

    MEDICAL BUILDING • 12,987 SF
    Value Estimation
    $6,010,000
    4020 Merle Hay Rd, Des Moines, IA 50310-1310
    View details
    1540 High St, Unit 203

    1540 High St, Unit 203

    MEDICAL BUILDING • 13,864 SF
    Value Estimation
    $1,190,000
    1540 High St, Des Moines, IA 50309-3106
    View details
    4119 9th St

    4119 9th St

    MEDICAL BUILDING • 4,405 SF
    Value Estimation
    $985,000
    4119 9th St, Des Moines, IA 50315-3466
    View details
    7481 Us Hwy 69

    7481 Us Hwy 69

    MEDICAL BUILDING • 12,697 SF
    Value Estimation by Request
    7481 Us Hwy 69, Des Moines, IA 50320
    View details

    Des Moines, IA Medical Office Space Investment Opportunities Market Analysis

    Explore 102 medical office space for sale in Des Moines, IA, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 5,775 square feet of properties for sale, with an estimated market value of $849,000.

    Sale prices for medical spaces in Des Moines, IA start at $389,000, averaging $424,500, and reaching up to $460,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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