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    Des Moines, IA Commercial Real Estate for Sale

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    Dubuque, IA Ankeny, IA Cedar Rapids, IA
    215 results
    Automotive Shop in Des Moines
    $315,000
    0.16 Acres

    Automotive Shop in Des Moines

    1501 6th Avenue, Des Moines, IA 50314

    Fully functioning automotive shop in high-traffic Des Moines location.

    • Optimal location with high daily traffic for HIGH EXPOSURE
    • Fully functioning automotive shop
    • Car lift INCLUDED with the property
    • Potential to convert to a different business
    • Building constructed with durable brick and block materials
    Updated: Nov 10, 2025
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    Des Moines Development Opportunity
    $300,000
    1.92 Acres

    Des Moines Development Opportunity

    3101 SE 22nd Street, Des Moines, IA 50320

    1.92 acres of land zoned RX1 in Des Moines.

    • 1.92 acre development opportunity
    • Zoned RX1, suitable for townhomes, commercial/residential mix, or multi‑family
    • Build‑to‑suit option available
    • Sewer and electric available at the street for easy connection
    • Located on DM SE side
    Updated: Dec 5, 2025
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    Historic Mixed-Use Property For Sale
    $225,000
    3,550 SF

    Historic Mixed-Use Property For Sale

    Unique mixed-use property with commercial space and residential apartments.

    3516 SW 9th Street, Des Moines, IA 50315
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    Des Moines Duplex: Investment Opportunity
    $195,000
    1,282 SF

    Des Moines Duplex: Investment Opportunity

    Charming Des Moines duplex, ideal for investors or homeowners.

    1442 34th Street, Des Moines, IA 50311
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    Commercial Land Near DSM Airport
    $499,000
    1.42 Acres

    Commercial Land Near DSM Airport

    Ideal commercial location across from Des Moines Airport.

    2501 Mckinley Avenue, Des Moines, IA 50321
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    Des Moines Retail Property For Sale
    $1,600,000
    1.09 Acres

    Des Moines Retail Property For Sale

    Retail property available for sale in Des Moines, Iowa.

    606 E Army Post Road, Des Moines, IA 50315
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    Ocean-View Development Land in Ostional
    $2,000,000

    Ocean-View Development Land in Ostional

    19.84-acre development land with ocean views, subdivided into 20 lots.

    Des Moines, 50309
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    Productive Farmland Near Des Moines
    Contact for pricing
    231.09 Acres

    Productive Farmland Near Des Moines

    231-acre farm with high CSR2 rating and highway access.

    Hartford Avenue, Des Moines, IA 50320
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    Retail Center in Beaverdale Neighborhood
    $915,000
    8,600 SF

    Retail Center in Beaverdale Neighborhood

    Established retail center in Des Moines' desirable Beaverdale neighborhood.

    3708 Beaver Avenue, Des Moines, IA 50310
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    Des Moines Flex/Industrial Building
    $675,000
    8,112 SF

    Des Moines Flex/Industrial Building

    Well-maintained flex building with warehouse and office space for sale.

    1429 2nd Avenue, Des Moines, IA 50314
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    Des Moines Land Opportunity
    $149,950
    2.49 Acres

    Des Moines Land Opportunity

    2.49-acre parcel with potential for high-density residential conversion.

    2009-2013 Martin Luther King Jr Parkway, Des Moines, IA 50314
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    Luxury Villas Near Costa Rica Beach
    $799,000
    2,691 SF

    Luxury Villas Near Costa Rica Beach

    Boutique villas, walk to beach, income potential.

    Des Moines, 50308
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    Two-Story Office Building For Sale
    $300,000
    1,872 SF

    Two-Story Office Building For Sale

    1,872 SF office building with partially finished basement.

    3161 Southeast 22nd Street, Des Moines, IA 50320
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    Retail Space in Harding Hills
    $975,000
    12,220 SF

    Retail Space in Harding Hills

    Junior anchor space available for sale or lease.

    3430 Martin Luther King Jr Pkwy, Des Moines, IA
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    Profitable ATV Tour Business Opportunity
    $200,000

    Profitable ATV Tour Business Opportunity

    Turnkey ATV tour business for sale in Tamarindo, Costa Rica.

    Des Moines, 50309
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    Des Moines Commercial Corridor Property
    $550,000

    Des Moines Commercial Corridor Property

    Well-maintained property in accessible commercial corridor, ideal for various businesses.

    3508 Delaware Ave, Des Moines, IA 50313
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    Retail Property in Capitol East
    $725,000
    3,168 SF

    Retail Property in Capitol East

    Retail space with high visibility in Capitol East neighborhood.

    521 East 14th Street, Des Moines, IA 50316
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    Turnkey Bank in Thriving District
    $1,700,000
    5,000 SF

    Turnkey Bank in Thriving District

    Spacious bank building with redevelopment potential in a walkable neighborhood.

    2805 Beaver Ave |, Des Moines, IA 50310
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    Versatile Des Moines Commercial Building
    $2,133,600
    17,780 SF

    Versatile Des Moines Commercial Building

    17,780 SF building with office, shop, and warehouse space.

    1536 E Army Post Rd, Des Moines, IA 50320
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    Des Moines Office Building For Sale
    $389,000
    2,152 SF

    Des Moines Office Building For Sale

    Two-story office building near Des Moines VA Medical Center.

    3811 38th St., Des Moines, IA 50310
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    Des Moines Commercial Development Land
    $300,000

    Des Moines Commercial Development Land

    Commercial development land for sale in Des Moines, Iowa.

    1475 Hart Avenue, Des Moines, IA 50320
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    Freestanding Retail Building For Sale
    $750,000

    Freestanding Retail Building For Sale

    Freestanding retail building in a mixed-use neighborhood.

    4931 Douglas Ave, Des Moines, IA 50310
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    Downtown Des Moines Office Condo
    $146,700
    1,467 SF

    Downtown Des Moines Office Condo

    Office condo with parking in the heart of Des Moines.

    300 East Walnut Street, Des Moines, IA 50309
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    Des Moines Commercial Corridor Property
    $600,000
    2,507 SF

    Des Moines Commercial Corridor Property

    Well-maintained property in accessible commercial corridor with high visibility.

    3508 Delaware Ave, Des Moines, IA 50313
    View details

    Des Moines, IA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 5000+ commercial real estate for sale in Des Moines, IA, showcased through 215 active listings on our real estate platform. These investment opportunities span a total of 4,127,689 square feet of properties for sale, with an estimated market value of $21,160,220.

    Sale prices for business properties in Des Moines, IA start at $149,950, averaging $1,410,681, and reaching up to $5,890,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Commercial real estate for Sale Near Des Moines, IA

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    Most Searched ZIP Codes in Des Moines, IA

    • 50309
    • 50310
    • 50313
    • 50321
    • 50314
    • 50317
    • 50320
    • 50315
    • 50316
    • 50312
    • 50322

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