Des Moines, IA Commercial Real Estate for Lease

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196 properties
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Corner Commercial Land
Corner Commercial Land

1500-1506 E Grand Ave, Des Moines, IA 50316

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0.34 AC lot

The site carries NPC (Neighborhood Pedestrian Commercial District) zoning.

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Office Unit with Capitol Views
Office Unit with Capitol Views

400 E Court Ave, Des Moines, IA 50309

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885 sqft

Workspace in Des Moines’ East Village includes on-site parking and access to outdoor seating areas.

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Commercial Land For Lease
Commercial Land For Lease

1350 Martin Luther King Jr Pkwy, Des Moines, IA 50309

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10.95 AC lot

Commercial land site in a lake and downtown recreation area with utilities already in place and traffic count of 15,000 vpd.

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Based on your search, we've compiled 393 Potential Opportunities for your consideration. Besides 196 Active listings in Des Moines, IA, we suggest exploring alternatives. Consider Similar 193 Spaces for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Office Space on Hickman Road
Office Space on Hickman Road

7900 Hickman Road, Windsor Heights, IA 50324

$12.50 SF/Yr
2,344 sqft

Office space for rent with excellent location and amenities.

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Medical Office Space Available
Medical Office Space Available

7180 Hickman Rd, Windsor Heights, IA 50324

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2,930 sqft

Former orthodontics office with operatories, lab, and private offices.

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Office Units at The Square
Office Units at The Square

4440-4456 128th St, Urbandale, IA 50323

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3,600 sqft

Commercial office space situated off Meredith and NW 128th Street in Urbandale.

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Flex Space With Dock Access
Flex Space With Dock Access

4601-4749 121st Street, Urbandale, IA 50323

Contact for pricing

Business park space accommodates office, showroom, and warehouse functions with interstate access and abundant natural light.

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Similar Spaces for Sale in Des Moines, IA

Consider Similar Space for Sale. We found 193 Spaces matching your search parameters.

Veterinary Medical Center
Veterinary Medical Center

3451 Hubbell Ave, Des Moines, IA 50317

$985,000
4,000 sqft

Freestanding veterinary care facility with an NN lease structure and a five-year renewal option.

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Standalone One-Story Office Building
Standalone One-Story Office Building

2721 SW 30th St, Des Moines, IA 50321

$590,000
3,868 sqft 0.63 AC lot

Flexible professional layout with private offices, conference space, kitchen, and multiple restrooms.

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Historic Court Avenue Retail Opportunity
Historic Court Avenue Retail Opportunity

310 Court Ave, Des Moines, IA 50309

$1,350,000
7,999 sqft

Prime retail/restaurant space in Des Moines' historic Court District.

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Heavy Industrial Warehouse with Office
Heavy Industrial Warehouse with Office

4485 Northeast 22nd Street, Des Moines, IA 50313

$2,150,000
10,500 sqft 4.65 AC lot

Warehouse with heavy industrial zoning, finished office space, and multiple loading doors for practical industrial operations.

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Office Building with Finished Basement
Office Building with Finished Basement

4001 Ingersoll Avenue, Des Moines, IA 50312

$576,036
4,372 sqft

Mid-century office property with a brick-and-concrete exterior, finished lower level, and on-site parking.

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Animal Medical Office
Animal Medical Office

4520 Merle Hay Rd, Des Moines, IA 50310

$625,000
2,250 sqft 0.48 AC lot

Existing veterinary clinic within a Highway Commercial District property in Des Moines.

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Mixed-Use Property with Two Buildings
Mixed-Use Property with Two Buildings

2312 Forest Avenue, Des Moines, IA 50311

$200,000
7,238 sqft 0.26 AC lot

Two structures combine commercial space with residential redevelopment areas.

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Commercial Land Redevelopment Site
Commercial Land Redevelopment Site

310 SE 7th St, Des Moines, IA 50309

$2,680,000
2 sqft

Surrounding properties include retail, multifamily, industrial, and office uses.

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Industrial Flex Building with Crane
Industrial Flex Building with Crane

700 New York Avenue, Des Moines, IA 50313

$4,200,000
36,430 sqft 2.06 AC lot

Renovated commercial facility with docks, drive-in access, crane system, and secured outdoor storage.

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Four-Bay Auto Shop
Four-Bay Auto Shop

2603 Douglas Avenue, Des Moines, IA 50310

$700,000
0.73 AC lot

A customer reception area, office, kitchenette, and restroom complement the service-bay layout.

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Warehouse Condominium with Mezzanine Office
Warehouse Condominium with Mezzanine Office

7640 SW 22nd Street 105 & 106, Des Moines, IA 50312

$595,000
3,000 sqft

Climate-controlled industrial condominium with specialized equipment, dual electrical service, restrooms, and a break room.

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Office Suite with Skywalk Access
Office Suite with Skywalk Access

300 East Walnut Street, Des Moines, IA 50309

$129,000
1,467 sqft

3,500 SF suite offers private offices, a conference room, and a reception area with skywalk connectivity.

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Office Building with 2025 Roof HVAC
Office Building with 2025 Roof HVAC

2301 Rittenhouse Street, Des Moines, IA 50321

$3,275,000
29,408 sqft

Recent roof and HVAC replacement in 2025 support this office building near the Fleur Drive corridor.

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Retail Property in Capitol East
Retail Property in Capitol East

521 East 14th Street, Des Moines, IA 50316

$569,124
3,168 sqft

Retail space with high visibility in Capitol East neighborhood.

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Freestanding Retail Building
Freestanding Retail Building

3400 East 25th Street, Des Moines, IA 50317

$384,024
1,018 sqft 1.70 AC lot

Standalone retail property positioned on a 1.7-acre parcel in Des Moines.

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Retail Property in Des Moines
Retail Property in Des Moines

6200 Southeast 14th Street, Des Moines, IA 50320

$3,150,000
14,560 sqft

Single-tenant retail property operating as a Walgreens.

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Des Moines Office Building For Sale
Des Moines Office Building For Sale

2620 Fleur Dr, Des Moines, IA 50321

$800,000
4,500 sqft

Office building with 10,816 square feet available for sale.

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Des Moines Redevelopment Opportunity
Des Moines Redevelopment Opportunity

115 7th Street, Des Moines, IA 50309

$700,000
1,291 sqft

Building for sale or redevelopment in downtown Des Moines.

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Des Moines Industrial Investment Property
Des Moines Industrial Investment Property

1631 2nd Ave, Des Moines, IA 50314

$1,400,000
9,409 sqft

Fully occupied industrial property with long-term tenant in Des Moines.

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Office Units with Retail Space
Office Units with Retail Space

6307 Hickman Road, Des Moines, IA 50322

$211,213
2,880 sqft

Office and retail space is positioned along Hickman Road near Interstate 80/35 access.

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Industrial Warehouse and Shop Buildings
Industrial Warehouse and Shop Buildings

6212 NE 14th Street, Des Moines, IA 50313

$2,000,000
7.99 AC lot

Two industrial buildings combine warehouse, office, and shop space on a large LI-zoned parcel.

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