Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Mixed-Use
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Des Moines, IA Mixed-use Properties for Sale

    Notify Me
    List
    Map
    Dubuque, IA Ankeny, IA Cedar Rapids, IA
    Historic Mixed-Use Property For Sale
    $225,000
    3,550 SF

    Historic Mixed-Use Property For Sale

    3516 SW 9th Street, Des Moines, IA 50315

    Unique mixed-use property with commercial space and residential apartments.

    • Strong cash flow potential from fully leased commercial and residential units.
    • New roof (2019) and HVAC systems (2025) provide peace of mind.
    • High‑visibility commercial space on a high‑traffic corridor (17,000+ vehicles per day).
    • Two spacious 2‑bedroom apartments with large living rooms and open kitchens.
    • Unique historic property with character, formerly a fire station and library.
    Updated: Jan 8
    View details
    Des Moines Land Opportunity
    $149,950
    2.49 Acres

    Des Moines Land Opportunity

    2009-2013 Martin Luther King Jr Parkway, Des Moines, IA 50314

    2.49-acre parcel with potential for high-density residential conversion.

    • Massive potential for RH (High Density Residential) conversion.
    • Ideal for row houses, townhouses, or bi‑attached homes.
    • 2.49‑acre parcel offers a rare blank canvas.
    • Quiet residential pocket just 5 minutes from the Downtown core.
    • Rear‑alley access, perfect for a live‑work setup or commercial storefronts.
    Updated: Jan 22
    View details
    Mixed-Use Property Near Grandview University
    $286,000
    3,683 SF

    Mixed-Use Property Near Grandview University

    High-visibility mixed-use property in a primary commercial corridor.

    3001 E 14th St, Des Moines, IA 50316
    View details
    Historic Court Avenue Building For Sale
    Contact for pricing
    36,000 SF

    Historic Court Avenue Building For Sale

    Historic building in the Court Avenue district available for sale.

    216 Court Ave, Des Moines, IA 50309
    View details
    Luxury Mixed-Use Community in Des Moines
    Contact for pricing
    16,901 SF

    Luxury Mixed-Use Community in Des Moines

    42-unit mixed-use property with apartments, townhomes, and medical office.

    4362 Hickman Road, Des Moines, IA 50310
    View details
    Based on your search, we've compiled 866 Potential Opportunities for your consideration. Besides 5 Active listings in Des Moines, IA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 853 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mixed-Use Development For Sale
    $3,417,227
    12,486 SF

    Mixed-Use Development For Sale

    20,400 SF mixed-use property with retail, office, and apartments.

    7040 NE 14th St, Ankeny, IA
    View details
    Retail, Multifamily, Office, Mixed Use
    $3,417,227
    6,358 SF

    Retail, Multifamily, Office, Mixed Use

    Mixed-use properties · 6,358 SF

    7040 NE 14th St, Ankeny, IA 50023
    View details
    Prime Commercial Development Site
    $718,740
    10,000 SF

    Prime Commercial Development Site

    1.10 acre commercial site with high visibility in Grimes, Iowa.

    3505 SE Grimes Blvd, Grimes, IA 50111
    View details
    Highway Commercial Land Available
    Contact for pricing

    Highway Commercial Land Available

    Highway commercial land near major retailers and residential developments.

    NE Corner of HWY 141 & HWY 44, Grimes, IA 50111
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Des Moines Development Opportunity
    $240,000

    Des Moines Development Opportunity

    Prime development opportunity near downtown and medical facilities.

    2515 24th St, Des Moines, IA 50310
    View details
    Des Moines Land For Sale
    Contact for pricing
    0.15 Acres

    Des Moines Land For Sale

    6,500 sq ft lot in Des Moines, Iowa.

    3107 2nd Avenue, Des Moines, IA 50313
    View details
    Des Moines Development Opportunity
    $300,000

    Des Moines Development Opportunity

    1.92 acres of land suitable for various development projects.

    3101 SE 22nd St, Des Moines, IA 50320
    View details
    Des Moines Development Opportunity
    $300,000
    1.92 Acres

    Des Moines Development Opportunity

    1.92 acres of land zoned RX1 in Des Moines.

    3101 SE 22nd Street, Des Moines, IA 50320
    View details

    Explore Off-Market Properties in Des Moines, IA

    Consider similar Off-Market properties in Des Moines, IA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    5109 17th St

    5109 17th St

    OFFICE/RESIDENTIAL (MIXED USE) • 16,900 SF
    Value Estimation
    $2,565,000
    5109 17th St, Des Moines, IA 50313-2116
    View details
    607 Euclid Ave

    607 Euclid Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 2,160 SF
    Value Estimation by Request
    607 Euclid Ave, Des Moines, IA 50313-4556
    View details
    1515 Euclid Ave

    1515 Euclid Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 65,620 SF
    Value Estimation
    $5,495,000
    1515 Euclid Ave, Des Moines, IA 50313-4760
    View details
    3504 9th St

    3504 9th St

    OFFICE/RESIDENTIAL (MIXED USE) • 8,307 SF
    Value Estimation by Request
    3504 9th St, Des Moines, IA 50315-3131
    View details
    1910 Ingersoll Ave

    1910 Ingersoll Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 12,146 SF
    Value Estimation
    $945,000
    1910 Ingersoll Ave, Des Moines, IA 50309
    View details
    2203 Grand Ave

    2203 Grand Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 10,563 SF
    Value Estimation
    $995,000
    2203 Grand Ave, Des Moines, IA 50312-5305
    View details
    2319 Bell Ave

    2319 Bell Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 15,554 SF
    Value Estimation
    $1,020,000
    2319 Bell Ave, Des Moines, IA 50321-1114
    View details
    1751 Guthrie Ave

    1751 Guthrie Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 25,200 SF
    Value Estimation
    $1,835,000
    1751 Guthrie Ave, Des Moines, IA 50316-2135
    View details
    207 9th St

    207 9th St

    OFFICE/RESIDENTIAL (MIXED USE) • 54,368 SF
    Value Estimation by Request
    207 9th St, Des Moines, IA 50309-3601
    View details
    1233 25th St

    1233 25th St

    OFFICE/RESIDENTIAL (MIXED USE) • 18,534 SF
    Value Estimation by Request
    1233 25th St, Des Moines, IA 50311
    View details
    1220 24th St

    1220 24th St

    OFFICE/RESIDENTIAL (MIXED USE) • 5,046 SF
    Value Estimation by Request
    1220 24th St, Des Moines, IA 50317
    View details
    535 Army Post Rd

    535 Army Post Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 8,304 SF
    Value Estimation
    $1,135,000
    535 Army Post Rd, Des Moines, IA 50315-5981
    View details
    1525 Vermont St

    1525 Vermont St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,800 SF
    Value Estimation by Request
    1525 Vermont St, Des Moines, IA 50314-3523
    View details
    505 Sheridan Ave

    505 Sheridan Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 12,449 SF
    Value Estimation
    $1,330,000
    505 Sheridan Ave, Des Moines, IA 50313
    View details
    5085 17th St

    5085 17th St

    OFFICE/RESIDENTIAL (MIXED USE) • 81,882 SF
    Value Estimation
    $4,665,000
    5085 17th St, Des Moines, IA 50313-2114
    View details
    4215 Hubbell Ave

    4215 Hubbell Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 2,000 SF
    Value Estimation by Request
    4215 Hubbell Ave, Des Moines, IA 50317-4507
    View details
    2301 Frst Ave

    2301 Frst Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 1,695 SF
    Value Estimation by Request
    2301 Frst Ave, Des Moines, IA 50311-3113
    View details
    204 12th St

    204 12th St

    OFFICE/RESIDENTIAL (MIXED USE) • 39,885 SF
    Value Estimation
    $2,400,000
    204 12th St, Des Moines, IA 50391-5001
    View details
    4900 Franklin Ave

    4900 Franklin Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 3,234 SF
    Value Estimation by Request
    4900 Franklin Ave, Des Moines, IA 50310-1901
    View details

    Des Moines, IA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 858 mixed-use properties for sale in Des Moines, IA, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 24,341,650 square feet of properties for sale, with an estimated market value of $340,349,950.

    Sale prices for multi use buildings in Des Moines, IA start at $60,000, averaging $590,885, and reaching up to $10,605,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Mixed-use properties for Sale Near Des Moines, IA

    Popular Searches in Des Moines, IA

    Popular Categories

    Most Searched ZIP Codes in Des Moines, IA

    • 50309
    • 50310
    • 50314
    • 50315
    • 50316

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!