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    Des Moines, IA Medical Office Space for Lease

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    West Des Moines, IA Cedar Rapids, IA Ankeny, IA
    9 results
    High Visibility Retail/Office Space
    $15 SF/Yr
    6,650 SF

    High Visibility Retail/Office Space

    6201 Southeast 14th Street, Des Moines, IA 50320

    Retail or medical office space in a high-traffic location.

    • Highly visible retail space at a major intersection.
    • Ideal for retail, medical office, or service occupiers.
    • Convenient internal access to Olive Garden/Raising Cane’s/Dollar Tree.
    • Located on Des Moines’ Southside.
    • Pylon signage available along SE 14th Street.
    Updated: Mar 25
    View details
    Medical Suite in Des Moines
    $18 SF/Yr
    2,247 SF

    Medical Suite in Des Moines

    1215-1415 Pleasant St, Des Moines, IA

    Medical suite for lease within Methodist Medical Center Campus.

    • Located on the Methodist Medical Center Campus
    • Onsite parking provided by an adjacent parking ramp
    • Ideal location for healthcare professionals
    • 2,247 USF available in Suite 102
    • Suite 102 is on the first floor
    Updated: Oct 22, 2025
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    Des Moines Medical Office Space
    $22 SF/Yr
    7,572 SF

    Des Moines Medical Office Space

    Medical office space in Des Moines' major medical corridor.

    330 Laurel Street, Des Moines, IA 50314
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    Fleur Drive Retail/Medical Space
    $15 SF/Yr
    2,275 SF

    Fleur Drive Retail/Medical Space

    Well-maintained retail or medical space in a high-traffic area.

    4214 Fleur Dr, Des Moines, IA
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    Renovated Office Building in Sherman Hills
    $22 SF/Yr
    2,217 SF

    Renovated Office Building in Sherman Hills

    Historically renovated office building suitable for office or medical use.

    800 19th St, Des Moines, IA
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    Medical Office Space Available
    Contact for pricing
    9,608 SF

    Medical Office Space Available

    Medical office building with on-site parking in high-traffic area.

    1530 E Euclid Ave, Des Moines, IA 50313
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    Medical Surgery Center For Lease
    Contact for pricing
    24,000 SF

    Medical Surgery Center For Lease

    Class A medical surgery center adjacent to Mercy One Medical Center.

    450 Laurel St, Des Moines, IA 50314
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    Medical Surgery Center for Lease
    Contact for pricing
    24,000 SF

    Medical Surgery Center for Lease

    Class A medical surgery center space available for lease.

    450 Laurel St, Des Moines, IA 50314
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    Des Moines Office Space Available
    Contact for pricing
    2,000 SF

    Des Moines Office Space Available

    Office space available for lease in Des Moines, Iowa.

    4919 Douglas Ave, Des Moines, IA 50310
    View details
    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 9 Active listings in Des Moines, IA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Turnkey Medical Space in Clive
    Contact for pricing
    2,753 SF

    Turnkey Medical Space in Clive

    Move-in ready medical space in a growing healthcare corridor.

    1601 NW 114th St, Clive, IA 50325
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    Turnkey Medical Space in Clive
    $17 SF/Yr
    2,463 SF

    Turnkey Medical Space in Clive

    Move-in ready medical space in a growing healthcare corridor.

    1601 NW 114th St, Clive, IA
    View details
    Medical Office Space Available
    $15 SF/Yr
    1,413 SF

    Medical Office Space Available

    Ready-to-use medical suite with ample parking and prime location.

    1031 Office Park Rd, West Des Moines, IA 50265
    View details
    Office/Medical Suites For Rent
    Contact for pricing
    5,073 SF

    Office/Medical Suites For Rent

    Office and medical suites available in West Des Moines, Iowa.

    1031 Office Park Rd, West Des Moines, IA 50265
    View details

    Explore Similar Spaces for Sale in Des Moines, IA

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Des Moines Office Building For Sale
    $389,000
    2,152 SF

    Des Moines Office Building For Sale

    Two-story office building near Des Moines VA Medical Center.

    3811 38th St., Des Moines, IA 50310
    View details
    Former Dentist Office with Space
    Contact for pricing
    7,260 SF

    Former Dentist Office with Space

    First and second floor office spaces available for lease.

    4919 Douglas Avenue, Des Moines, IA 50310
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    Medical Office Near Mercy Campus
    $460,000

    Medical Office Near Mercy Campus

    Medical office space for sale near Mercy Medical Campus.

    303 University Avenue, Des Moines, IA 50314
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    Medical Office Building For Sale
    $460,000
    3,623 SF

    Medical Office Building For Sale

    Single-story medical office building with University Avenue frontage.

    303 University Avenue, Des Moines, IA 50314
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    Luxury Mixed-Use Community in Des Moines
    Contact for pricing
    16,901 SF

    Luxury Mixed-Use Community in Des Moines

    42-unit mixed-use property with apartments, townhomes, and medical office.

    4362 Hickman Road, Des Moines, IA 50310
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Highway 72 Corner Lot
    $6,500/Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details
    Grand Junction Commercial Land Opportunity
    $17,728/Mo

    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
    View details
    Grand Junction Commercial Land Lease
    $9,656/Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details
    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details

    Des Moines, IA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Des Moines, IA with 9 listings featured on our commercial real estate exchange. The current inventory includes 20,961 square feet of properties with an estimated lease value of $92 SF/Yr.

    Estimated lease rates for Medical Office Space in Des Moines, IA begin at $15 SF/Yr, with an average of $18 SF/Yr and extend to $22 SF/Yr.
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    Most Searched ZIP Codes in Des Moines, IA

    • 50314
    • 50310
    • 50313
    • 50320

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