Des Moines, IA Medical Office Space for Rent & Lease

Updated: Jun 23

Medical Office Building with Parking

1530 East Euclid Avenue, Des Moines, IA 50313

$15 SF/Yr

9,608 sqft 1.07 AC lot

Well‑maintained medical office building with up to 9,608 SF total space
1.074‑acre lot with on‑site parking for office and medical use
Includes private exam rooms and offices
Dedicated lab space plus storage areas
Available monument signage

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Updated: Jul 17

Medical Office Building

2459 East Euclid Avenue, Des Moines, IA 50317

$20 SF/Yr

6,240 sqft 0.53 AC lot

Well‑maintained medical office building with up to 6,240 SF of total space
0.53‑acre lot with on‑site parking
Space offers versatile options for medical use or standard office use

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West Mall Inline Retail Spaces

1111 East Army Post Road, Des Moines, IA 50315

$17.50 SF/Yr

15,665 sqft

Flexible inline retail space in a redeveloped mixed-use center, including a 45,000 SF former theatre building.

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Des Moines Medical Office Space

330 Laurel Street, Des Moines, IA 50314

$22 SF/Yr

7,572 sqft

Medical office space in Des Moines' major medical corridor.

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Grand Avenue Office and Clinic

3200 Grand Avenue, Des Moines, IA 50312

$22 SF/Yr

152,854 sqft

First-class office and clinic space with parking ramp.

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Medical Office Space

4520 Merle Hay Rd, Des Moines, IA 50310

$18 SF/Yr

Veterinary clinic space is available for lease at this Des Moines commercial property.

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Medical Office Space for Lease

850 Dickman Rd, Des Moines, IA 50315

Contact for pricing

22,572 sqft

Medical office space is available for lease at 850 Dickman Rd in Des Moines, IA.

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Renovated Office Building in Sherman Hills

800 19th Street, Des Moines, IA 50314

$22 SF/Yr

Historically renovated office building suitable for office or medical use.

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Medical Surgery Center for Lease

450 Laurel St, Des Moines, IA 50314

Contact for pricing

24,000 sqft

Class A medical surgery center space available for lease.

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Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 9 Active listings in Des Moines, IA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Turnkey Medical Office Suite

5731 Greendale Rd, Johnston, IA 50131

$18 SF/Yr

1,890 sqft

Freestanding suite with four sectioned offices, private restroom, and kitchenette inside a well-maintained Johnston office building.

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Johnston Office Space For Lease

6105 Northwest 86th Street, Johnston, IA 50131

$20 SF/Yr

4,259 sqft 1.93 AC lot

Medical/Professional office space available in Johnston, Iowa.

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Medical Office Space Available

1031 Office Park Rd, West Des Moines, IA 50265

Contact for pricing

1,413 sqft 8.21 AC lot

Ready-to-use medical suite with ample parking and prime location.

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Medical Office Suite

1300 50th St, West Des Moines, IA 50266

Contact for pricing

1,850 sqft

Built-out office suite includes six offices, reception, break room, and a private restroom.

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Similar Spaces for Sale in Des Moines, IA

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Animal Medical Office

4520 Merle Hay Rd, Des Moines, IA 50310

$625,000

2,250 sqft 0.48 AC lot

Existing veterinary clinic within a Highway Commercial District property in Des Moines.

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Freestanding Medical Office Building

3310 East Euclid Avenue, Des Moines, IA 50317

Contact for pricing

5,388 sqft 1.30 AC lot

Clinical buildout includes waiting, consultation, surgical, nursing, and recovery areas.

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Former Dentist Office with Space

4919 Douglas Avenue, Des Moines, IA 50310

Contact for pricing

7,260 sqft 1.46 AC lot

First and second floor office spaces available for lease.

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Office Condo with Underground Parking

300 Walnut St, Des Moines, IA 50309

Contact for pricing

1,467 sqft

Office condo with reception, multiple private offices, and direct skywalk access plus heated underground parking.

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Medical Office Near Mercy Campus

303 University Avenue, Des Moines, IA 50314

$460,000

Medical office space for sale near Mercy Medical Campus.

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Medical Office with Exam Rooms

1201 Pennsylvania Ave, Des Moines, IA 50316

Contact for pricing

Well-maintained medical office with dedicated clinical, administrative, imaging, and conference areas.

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Des Moines, IA Medical Office Space Lease Rates & Market Statistics

Browse 9 Medical Office Space listings for lease in Des Moines, IA on Realmo, a commercial real estate marketplace serving the Des Moines area. The current inventory totals 238,511 square feet of properties.

Medical Office Space lease rates in Des Moines range from $15 SF/Yr at the entry level to $22 SF/Yr at the top of the market, averaging $19.50 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $19.50 SF/Yr, the local average runs 12% above Iowa's state average of $17.33 SF/Yr.

Des Moines accounts for 38% of the 24 medical office space listings currently available across Polk County, where nearby markets include West Des Moines and Johnston. Medical Office Space listings make up 10% of the 89 Office Spaces currently for lease in Des Moines, with asking rates averaging $19.50 SF/Yr — 29% above the citywide Office Spaces average of $15.12 SF/Yr. Tenants comparing options may also consider Office Units (45 listings) and Office buildings (36 listings) elsewhere in the Des Moines market.