Grimes, IA Commercial real estate for Rent & Lease

IA, West Des Moines - West Lakes Parkway

$129-$3,657/Mo

(972) 764-8885

IA, West Des Moines - West Lakes Parkway

Discover many ways to work your way in IA, West Des Moines - West Lakes Parkway

1601 Lakes Pkwy, West Des Moines, IA 50266

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IA, West Des Moines - One Corporate Place

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(972) 764-8885

IA, West Des Moines - One Corporate Place

Workspaces, services and support to help you work better in UT, Clearfield - 1412 Legend Hills Dr

1501 42Nd St, West Des Moines, IA 50266

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$22 SF/Yr

New Retail Center in Grimes

825 NE Gateway Dr., Grimes, IA 50111

New retail strip center near high-traffic area and entertainment district.

Located off heavily trafficked HWY 141.
Located just east of GrimesPlex, a new 50‑acre multi‑sport complex estimated to draw 1.5 million visitors per year.
Part of Hope District, a 200‑acre multi‑use entertainment district under construction.
New construction (built in 2022).
Located in Grimes, IA.

Updated: Mar 6

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$15 SF/Yr

2,101 SF

Retail Space on Highway 141

3600 SE Crossroads Dr, Grimes, IA

2,101 SF retail space for lease on Hwy 141.

High Traffic Count: See your business thrive with 40,000 cars passing by daily.
Convenient Location: Located on Hwy 141, just north of the I‑35 Grimes exit.
Rapidly Growing Community.
Retail Space: 2,101 SF available.
Co‑Tenants: Join Rolling Wok & Pho, El Huapango Mexican, and Grimes Liquor Shop.

Updated: Sep 8, 2025

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$12 SF/Yr

16,400 SF

Grimes Flex/Industrial Space Available

16,400 SF flex/industrial space for lease in Grimes, Iowa.

1405 Southeast 28th Street, Grimes, IA 50111

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3,264 SF

Grimes Flex Space Available

3,264 SF flex space for lease in Grimes.

3560 SW Brookside Dr, Grimes, IA 50111

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$6 SF/Yr

25,000 SF

Grimes Warehouse Space Available

25,000 sq ft warehouse space for lease.

200 SE 37th Street, Grimes, IA 50111

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$5 SF/Yr

New Industrial Warehouse Space Available

Modern warehouse space built in 2023 with 30-foot clearance.

501 SW 37th Street, Grimes, IA 50111

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64,984 SF

Grimes Flex Space For Lease

Flex space available for lease with fenced outdoor storage.

2800 SE Enterprise Dr, Grimes, IA 50111

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179,732 SF

Industrial Logistics Center For Lease

270,192 SF industrial space available for lease.

3901 SE Park Dr, Grimes, IA 50111

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$6 SF/Yr

20,000 SF

Grimes Industrial Space For Lease

20,000 SF industrial space available in Grimes, Iowa.

1300 SE Little Beaver Dr, Grimes, IA

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$8 SF/Yr

7,550 SF

Grimes Warehouse with Outdoor Storage

7,550 SF warehouse with fenced outdoor storage available for lease.

3000 SE Enterprise Dr, Grimes, IA

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Modern Office Space Available

Contemporary office space in a growing Des Moines community.

255 Southwest Brookside Drive, Grimes, IA 50111

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Brand-New Flexible Retail/Office Suites

Newly constructed suites with flexible sizes, ample parking, and easy access from Highway 141 for retail, office, medical, and service uses.

1220 NE Station Xing, Grimes, IA 50111

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2,500 SF

Grimes Flex/Industrial Space Available

2,500 SF flex/industrial space for lease in Grimes, Iowa.

3430 Southeast Destination Drive, Grimes, IA 50111

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$12 SF/Yr

5,000 SF

Grimes Industrial Space with Mezzanine

5,000 SF industrial space with mezzanine storage for rent.

3101 SE Destination Dr, Grimes, IA

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$18 SF/Yr

1,200 SF

Office Space with Private Offices

Office space featuring private offices, conference room, and break room.

309 SE Main St, Grimes, IA

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Land Adjacent to Hy-Vee

Land for rent adjacent to Hy-Vee in Grimes, Iowa.

360 NE Gateway Dr, Grimes, IA

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135,000 SF

Grimes Warehouse Space Available

135,000 square foot warehouse space for lease in Grimes.

1200 SE 19th St, Grimes, IA

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$6 SF/Yr

Warehouse with High Ceiling

Warehouse with 32-foot ceilings and excellent transportation access.

4201 S James St, Grimes, IA 50111

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105,000 SF

Industrial Space Available for Lease

105,000 SF industrial space available for lease in Grimes, Iowa.

4201 S James St, Grimes, IA 50111

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$22 SF/Yr

New Retail Center in Grimes

New retail strip center near high-traffic area and entertainment district.

825 NE Gateway Dr, Grimes, IA 50111

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1,440 SF

Retail Space in Grimes Center

1,440 SF retail space in a community retail center.

270 W 1st St, Grimes, IA 50111

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Commercial Space For Lease

Commercial space available for lease in Grimes, Iowa.

4201 S James St. Suite 240, Grimes, IA 50111

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Grimes, IA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Grimes, IA with 32 listings featured on our commercial real estate exchange. The current inventory includes 77,251 square feet of properties with an estimated lease value of $78 SF/Yr.

Estimated lease rates for Commercial real estate in Grimes, IA begin at $6 SF/Yr, with an average of $11 SF/Yr and extend to $18 SF/Yr.