Grimes, IA Commercial real estate for Rent & Lease

Updated: Nov 22, 2025

Grimes Flex/Industrial Space Available

3430 Southeast Destination Drive, Grimes, IA 50111

$10.50 SF/Yr

2,500 sqft

2,500 SF flex/industrial space
Located in Grimes, Iowa

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Updated: Nov 24, 2025

Grimes Industrial Space For Lease

1300 SE Little Beaver Dr, Grimes, IA 50111

$6.75 SF/Yr

20,000 sqft

Premier business park with I‑80/I‑35 access
Benefit from a warehouse with 24' clear height
Lease Rate: $6.75/SF NNN
Equipped with an ESFR Sprinkler system
Features 2 docks and 1 drive‑in door

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Grimes Flex/Industrial Space Available

1405 Southeast 28th Street, Grimes, IA 50111

$12.50 SF/Yr

16,400 sqft

16,400 SF flex/industrial space for lease in Grimes, Iowa.

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New Retail Center in Grimes

825 NE Gateway Dr., Grimes, IA 50111

$22 SF/Yr

New retail strip center near high-traffic area and entertainment district.

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Retail Space in Grimes Center

270 W 1st St, Grimes, IA 50111

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1,440 sqft

1,440 SF retail space in a community retail center.

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Grimes Warehouse Space Available

200 SE 37th Street, Grimes, IA 50111

$6.05 SF/Yr

25,000 sqft

25,000 sq ft warehouse space for lease.

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Endcap Retail Space

204 W 1st Street, Grimes, IA 50111

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Flexible commercial layout with outdoor display space and signage opportunities.

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Flex-Industrial Building with Showroom

3400 SE Crossroads Dr, Grimes, IA 50111

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20,000 sqft

Built in 2022, this flex-industrial building includes office, showroom, and warehouse space near busy Highway 141.

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Grimes Warehouse with Outdoor Storage

3000 SE Enterprise Dr, Grimes, IA

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7,550 sqft 2.41 AC lot

7,550 SF warehouse with fenced outdoor storage available for lease.

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Light Industrial Warehouse Facility

501 SW 37th St, Grimes, IA 50111

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100,000 sqft

Newly built 2023 warehouse offers 30-foot clear height with six dock doors and one drive-in door.

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Warehouse and Office Space Available

4405 SE Beisser Dr, Grimes, IA 50111

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40,000 sqft

5,000 SF warehouse with office and outdoor storage.

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Commercial Space For Lease

4201 S James St, Grimes, IA 50111

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105,000 sqft

Commercial space available for lease in Grimes, Iowa.

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Retail Building in Hope District

1101 E 1st St, Grimes, IA 50111

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4,488 sqft

20,054 sqft retail building at the entrance of Hope District.

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Retail/Flex Space at Busy Intersection

3505 SE Grimes Blvd, Grimes, IA 50111

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10,000 sqft

Up to 10,000 sq. ft. of retail/flex space available with visibility from Highway 141.

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Retail Space Available for Lease

1881 SE Princeton Dr, Grimes, IA 50111

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11,000 sqft 1.55 AC lot

Retail spaces ranging from 1,500 to 11,000 square feet.

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Prime Land Near HyVee

1200 E 1st St, Grimes, IA

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0.75 AC lot

0.750 acres of commercial land in rapidly growing community.

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Corner Land in Grimes, Iowa

S James Street & SW 19th Street, Grimes, IA 50111

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Corner commercial land available for rent in Grimes, Iowa.

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Based on your search, we've compiled 45 Potential Opportunities for your consideration. Besides 17 Active listings in Grimes, IA, we suggest exploring alternatives. Similar 28 Properties for Sales.

Similar Spaces for Sale in Grimes, IA

Consider Similar Space for Sale. We found 28 Spaces matching your search parameters.

Prime Commercial Development Site

3505 Se Grimes Blvd, Grimes, IA 50111

$716,775

10,000 sqft 1.10 AC lot

1.10 acre commercial site with high visibility in Grimes, Iowa.

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Grimes Industrial Land For Sale

3605 Southeast Gateway Drive, Grimes, IA 50111

$1,672,710

2 sqft 2.56 AC lot

2.56 AC lot near Highway 141 corridor in Grimes.

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C-2 Commercial Land

1651 SE 3rd Street, Grimes, IA 50111

$2,073,962

3.70 AC lot

The site carries C-2 zoning and is near a multi-use sports complex in Grimes.

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New Retail Center in Grimes