Grimes, IA Commercial Real Estate for Lease

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Johnston, IA Urbandale, IA Clive, IA Granger, IA Des Moines, IA Waukee, IA Elkhart, IA West Des Moines, IA
31 properties
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Flex R&D Space at Business Park
Updated: Jul 16
Flex R&D Space at Business Park

3060 SE Grimes Blvd, Grimes, IA 50111

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3,850 sqft
Flex R&D space available for lease in Gateway Business Park
Available square footage: 3,850 SF
Located at 3060 SE Grimes Blvd, Grimes, Iowa 50111
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Grimes Warehouse Space Available
Updated: Nov 22, 2025
Grimes Warehouse Space Available

2800 Southeast Destination Drive, Grimes, IA 50111

$12.50 SF/Yr
13,500 sqft
13,500 sq ft warehouse space
For lease
Located in Grimes
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Brand-New Flex Industrial Bays
Brand-New Flex Industrial Bays

1305 SE 25th St, Grimes, IA 50111

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12,800 sqft

Five standalone bays offer private entrances, drive-in doors, and dedicated outdoor storage for trailers and equipment.

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Grimes Flex/Industrial Space Available
Grimes Flex/Industrial Space Available

1405 Southeast 28th Street, Grimes, IA 50111

$12.50 SF/Yr
16,400 sqft

16,400 SF flex/industrial space for lease in Grimes, Iowa.

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New Retail Center in Grimes
New Retail Center in Grimes

825 NE Gateway Dr., Grimes, IA 50111

$22 SF/Yr

New retail strip center near high-traffic area and entertainment district.

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Industrial Warehouse with Office
Industrial Warehouse with Office

2800 SE Enterprise Dr, Grimes, IA 50111

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64,984 sqft

Warehouse includes 10 dock doors, 15'–25' clear height, and fenced outdoor storage alongside about 4,000 SF of office space.

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Grimes Warehouse Space Available
Grimes Warehouse Space Available

200 SE 37th Street, Grimes, IA 50111

$6.05 SF/Yr
25,000 sqft

25,000 sq ft warehouse space for lease.

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Grimes Flex Space For Lease
Grimes Flex Space For Lease

2800 SE Enterprise Dr, Grimes, IA 50111

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64,984 sqft

Flex space available for lease with fenced outdoor storage.

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Industrial Logistics Center For Lease
Industrial Logistics Center For Lease

3901 SE Park Dr, Grimes, IA 50111

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179,732 sqft

270,192 SF industrial space available for lease.

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Grimes Flex/Industrial Space Available
Grimes Flex/Industrial Space Available

3430 Southeast Destination Drive, Grimes, IA 50111

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2,500 sqft

2,500 SF flex/industrial space for lease in Grimes, Iowa.

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Brand-New Flexible Retail/Office Suites
Brand-New Flexible Retail/Office Suites

1220 NE Station Xing, Grimes, IA 50111

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Newly constructed suites with flexible sizes, ample parking, and easy access from Highway 141 for retail, office, medical, and service uses.

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Retail and Service Corridor Space
Retail and Service Corridor Space

1890 SE Destination Dr, Grimes, IA 50111

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Retail or service-oriented tenants can benefit from visibility and direct access to Highway 141.

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Industrial Warehouse with Outdoor Storage
Industrial Warehouse with Outdoor Storage

1101 Southeast 37th Street, Grimes, IA 50111

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Functional industrial building offers space for warehousing, light manufacturing, and service operations plus outdoor storage.

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Modern Office Space Available
Modern Office Space Available

255 Southwest Brookside Drive, Grimes, IA 50111

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Contemporary office space in a growing Des Moines community.

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Grimes Industrial Space For Lease
Grimes Industrial Space For Lease

1300 SE Little Beaver Dr, Grimes, IA

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20,000 sqft

20,000 SF industrial space available in Grimes, Iowa.

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Warehouse with Office and Yard
Warehouse with Office and Yard

1915 SE 41st St, Grimes, IA 50111

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Well-maintained warehouse with 4,655 SF of office, 2 drive-in doors, 14-foot clear height, and a fenced yard.

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Grimes Warehouse with Outdoor Storage
Grimes Warehouse with Outdoor Storage

3000 SE Enterprise Dr, Grimes, IA

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7,550 sqft

7,550 SF warehouse with fenced outdoor storage available for lease.

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Light Industrial Warehouse Facility
Light Industrial Warehouse Facility

501 SW 37th St, Grimes, IA 50111

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100,000 sqft

Newly built 2023 warehouse offers 30-foot clear height with six dock doors and one drive-in door.

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Retail Space in Grimes Center
Retail Space in Grimes Center

270 W 1st St, Grimes, IA 50111

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1,440 sqft

1,440 SF retail space in a community retail center.

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Flex Building in Grimes, Iowa
Flex Building in Grimes, Iowa

3800 SE Beisser Dr, Grimes, IA 50111

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9,375 sqft

Flex building with suites available for rent in Grimes, Iowa.

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Warehouse with High Ceiling
Warehouse with High Ceiling

4201 S James St, Grimes, IA 50111

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Warehouse with 32-foot ceilings and excellent transportation access.

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Retail Building in Hope District
Retail Building in Hope District

1101 E 1st St, Grimes, IA 50111

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20,054 sqft

20,054 sqft retail building at the entrance of Hope District.

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Commercial Space For Lease
Commercial Space For Lease

4201 S James St. Suite 240, Grimes, IA 50111

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Commercial space available for lease in Grimes, Iowa.

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Retail/Flex Space at Busy Intersection
Retail/Flex Space at Busy Intersection

3505 SE Grimes Blvd, Grimes, IA 50111

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10,000 sqft

Up to 10,000 sq. ft. of retail/flex space available with visibility from Highway 141.

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Grimes, IA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Grimes, IA with 31 listings featured on our commercial real estate exchange. The current inventory includes 54,900 square feet of properties with an estimated lease value of $31.05 SF/Yr.

Estimated lease rates for Commercial real estate in Grimes, IA begin at $6.05 SF/Yr, with an average of $10.35 SF/Yr and extend to $12.50 SF/Yr.
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