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    Port St Lucie, FL
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    Port St Lucie, FL Commercial Real Estate for Lease

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    Port Saint Lucie, FL Vero Beach, FL Jensen Beach, FL
    166 listings
    Renaissance Financial
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    Quincy Professional Plaza
    $2,200/Mo
    Quincy Professional Plaza

    medical, dentist, insurance, retail

    1803 S 25Th St, Unit Suite 5, Fort Pierce, FL 34947

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    Retail Space for Lease
    $4,476/Mo
    1,700 SF
    Retail Space for Lease

    Port St Lucie, FL 34986

    A retail space available for lease in Port St. Lucie, suited to businesses compatible with General Commercial zoning.
    • Built in 2007 with concrete construction materials
    • Central heating and central air conditioning
    • Flat roof
    • Carpet flooring throughout
    • Parking includes guest parking
    Updated: May 28
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    Move-in Ready Medical Office Condo
    $3,352/Mo
    1,734 SF
    Move-in Ready Medical Office Condo

    1801 S 23rd Street, Fort Pierce, FL 34950

    Medical office condo for lease near Lawnwood Medical Center.
    • Move‑in ready medical office condo near Lawnwood Medical Center.
    • Equipped with 4 exam rooms, large waiting/reception area, private doctor's office, lab/prep area, break room, and 2 bathrooms.
    • Ideal for a pediatrician, previously used as a pediatrics office.
    • Lease terms: Modified gross lease at $23 per sq ft, tenant pays rent, utilities, and increases in taxes/condo fees; escalating monthly rent for years 1‑3, CPI increases for years 4 & 5.
    • Recently installed new 200 amp 3 phase break panel.
    Updated: Apr 28
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    Medical Building Near St. Lucie Hospital
    $22 SF/Yr
    11,187 SF
    Medical Building Near St. Lucie Hospital

    Turnkey medical building in St. Lucie Medical Park.

    Port St Lucie, FL 34952

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    Fort Pierce Freestanding Office Space
    $6,000/Mo
    4,805 SF
    Fort Pierce Freestanding Office Space

    Freestanding office space in Fort Pierce, ideal for diverse businesses.

    706 N 7th Street, Fort Pierce, FL 34950

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    Turnkey Medical Office Suite
    $48,000 SF/Yr
    1,911 SF
    Turnkey Medical Office Suite

    Fully renovated suite includes exam rooms, private office, and a rear entrance for staff convenience.

    Port St Lucie, FL 34986

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    Versatile Facility in Fort Pierce
    $5,000/Mo
    4,028 SF
    Versatile Facility in Fort Pierce

    4,028 SF building suitable for various uses.

    2525 S 25th Street, Fort Pierce, FL 34981

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    Remodeled Commercial Building with Parking
    $4,500/Mo
    2,000 SF
    Remodeled Commercial Building with Parking

    Freestanding 2,000 sq ft building with parking in Fort Pierce.

    3801 Okeechobee Road, Fort Pierce, FL 34947

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    Private Entrance Professional Office Suite
    $2,667/Mo
    3,930 SF
    Private Entrance Professional Office Suite

    Professional office suite with dedicated entry, reception area, private bath, new central A/C, and five assigned parking spaces.

    501 SW, Port St Lucie, FL 34953

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    Landmark Office Building in Fort Pierce
    $17 SF/Yr
    5,400 SF
    Landmark Office Building in Fort Pierce

    5,400 sq ft office space available for lease.

    2222 Colonial Road, Fort Pierce, FL 34950

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    Fort Pierce Commercial Rental Space
    $18 SF/Yr
    2,400 SF
    Fort Pierce Commercial Rental Space

    2,400 SF commercial space with office and warehouse.

    405 Angle Road, Fort Pierce, FL 34947

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    Retail Space in Swan Plaza
    $2,500/Mo
    3,258 SF
    Retail Space in Swan Plaza

    In-line retail space in a high-traffic commercial plaza.

    Port St Lucie, FL 34983

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    Port St. Lucie Executive Suite
    $1,527/Mo
    833 SF
    Port St. Lucie Executive Suite

    Executive office suite in Port St. Lucie medical corridor.

    Port St Lucie, FL 34952

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    Flexible Co-working Space For Rent
    $3,000/Mo
    Flexible Co-working Space For Rent

    Co-working space in St. Lucie West, flexible terms.

    Port St Lucie, FL 34986

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    Updated Office Space in Marina
    $1,000/Mo
    8,385 SF
    Updated Office Space in Marina

    Recently updated office space in Fort Pierce's Harbortown Marina.

    2010 Harbortown W, Fort Pierce, FL 34946

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    Lake Whitney Business Park
    $19 SF/Yr
    Lake Whitney Business Park

    FOR LEASE 1776 Square Feet Warehouse with Office in St. Lucie West

    482 NW Lake Whitney Pl, Port St Lucie, FL 34986

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    Class A Office Suite Available
    $2,287/Mo
    940 SF
    Class A Office Suite Available

    Professional office suite with private offices and open space.

    Port St Lucie, FL 34952

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    Office with Marina View
    $1,500/Mo
    Office with Marina View

    Office space for rent with marina view and parking.

    2010 Harbortown Drive, Fort Pierce, FL 34946

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    Versatile Facility for Lease
    $5,000/Mo
    4,028 SF
    Versatile Facility for Lease

    4,028 SF building ideal for school or office use.

    2525 S 25th St, Fort Pierce, FL 34981

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    New Flexspace Warehouse Near Airport
    $21 SF/Yr
    88,400 SF
    New Flexspace Warehouse Near Airport

    Newly constructed flexspace warehouse with high ceilings and modern amenities.

    6509 St Lucie Boulevard, Fort Pierce, FL 34946

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    Retail Space in Swan Plaza
    $2,500/Mo
    1,000 SF
    Retail Space in Swan Plaza

    Retail space with high visibility in a thriving commercial plaza.

    Port St Lucie, FL 34983

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    Retail Space in Historic Downtown
    $12 SF/Yr
    10,000 SF
    Retail Space in Historic Downtown

    Retail spaces available in historic downtown Fort Pierce.

    2nd Street, Fort Pierce, FL 34950

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    Remodeled Commercial Building with Parking
    $4,500/Mo
    2,000 SF
    Remodeled Commercial Building with Parking

    Freestanding 2,000 SF building with parking in Fort Pierce.

    3801 Okeechobee Rd, Fort Pierce, FL 34947

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    Port St Lucie, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Port St Lucie, FL with 166 listings featured on our commercial real estate exchange. The current inventory includes 700,654 square feet of properties with an estimated lease value of $49,672.

    Estimated lease rates for Commercial real estate in Port St Lucie, FL begin at $1.43 SF/Yr, with an average of $628 /Mo and extend to $48,000.
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