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    Port St Lucie, FL Healthcare Properties for Sale

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    11 properties
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    Freestanding Medical Office Building
    Updated: Aug 3
    Freestanding Medical Office Building

    Port St Lucie, FL

    $3,300,000
    11,187 sqft 1.02 AC lot
    Freestanding medical office building with five medical suites
    Delivered vacant with a fully built‑out professional interior
    49 on‑site parking spaces
    1.02‑acre property directly adjacent to HCA Florida St. Lucie Hospital
    8 out of 10 AC units replaced within the last 5 years
    View details
    Freestanding Medical Office Building
    Updated: Oct 27, 2025
    Freestanding Medical Office Building

    1900 Nebraska Avenue, Fort Pierce, FL 34950

    $625,000
    2,100 sqft
    2,100‑square‑foot freestanding medical office building
    Three exam rooms and four bathrooms, including a doctor’s bath with shower
    Two offices, reception area, workstations, storage, and separate break areas
    Nine parking spaces plus circular patient drop‑off driveway
    Private physician carport at 1900 Nebraska Avenue
    View details
    Equipped Spa & Wellness Property
    Equipped Spa & Wellness Property

    Port St Lucie, FL

    $35,000
    1,000 sqft

    Operating salon space includes specialized stations, plumbing, furnishings, and a private treatment room.

    View details
    See what stands out in St. Lucie County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

    Cap Rate available after sign in
    NOI available after sign in
    Local Demand available after sign in
    Assisted Living Home with Pool
    Assisted Living Home with Pool

    2150 SW Imperial St, Port St Lucie, FL 34987

    $635,000
    2,864 sqft

    Custom-built CBS pool home operating as a proven home care assisted living business with fenced yard and screened patio.

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    Spa and Wellness Property with Salon
    Spa and Wellness Property with Salon

    5022 Turnpike Feeder Road, Fort Pierce, FL

    $485,000

    Existing salon improvements include massage rooms, security cameras, and a sound system.

    View details
    Assisted Living Home for Six
    Assisted Living Home for Six

    2749 SE Eagle Dr, Port St Lucie, FL 34984

    $685,000
    3,135 sqft

    Single-family home operating as an assisted living facility with capacity for six patients and three currently enrolled.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Turn-Key Medical Office Suite
    Turn-Key Medical Office Suite

    2506 Acorn Street Unit A-b, Fort Pierce, FL 34947

    Contact for pricing
    1,800 sqft

    Renovated medical/professional suite with five exam rooms, private offices, and two bathrooms plus a large on-site parking lot.

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    Turn-Key Hair Salon Opportunity
    Turn-Key Hair Salon Opportunity

    6969 Hancock Dr, Port St Lucie, FL 34952

    $35,000
    1,000 sqft

    Well-furnished, fully equipped salon setup with multiple stations, plumbing-ready manicure and pedicure, and a private treatment room.

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    Beauty Salon with Expansion Opportunity
    Beauty Salon with Expansion Opportunity

    5022 Turnpike Feeder Road, Fort Pierce, FL 34951

    $485,000
    15,000.00 AC lot

    Established beauty salon featuring 12 stations and two massage rooms in an 18-year-old CBS building.

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    Turn-Key Medical Office Suite
    Turn-Key Medical Office Suite

    A-b-2506 Acorn St, Fort Pierce, FL 34947

    Contact for pricing

    Newly renovated medical suite with five exam rooms, private offices, and a large dedicated parking lot.

    View details
    Spa & Wellness Business Opportunity
    Spa & Wellness Business Opportunity

    8001-7991 S Us Highway 1, Port St Lucie, FL 34952

    $60,000

    For sale spa and wellness property with an ongoing city application to add a beauty salon.

    View details
    Based on your search, we've compiled 27 Potential Opportunities for your consideration. Besides 11 Active listings in Port St Lucie, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 11 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Leased Medical Office Building
    Leased Medical Office Building

    3405 NW Federal Highway, Jensen Beach, FL 34957

    $3,000,000
    2.94 AC lot

    Two month-to-month leases provide flexibility within an occupied professional office property.

    View details
    Medical Office Suite with Private Rooms
    Medical Office Suite with Private Rooms

    C-2-829 18th St, Vero Beach, FL 32960

    $557,500

    Flexible layout includes treatment, consultation, storage, and restroom areas for professional medical or administrative operations.

    View details
    Residential Buildings Portfolio Sale-Leaseback
    Residential Buildings Portfolio Sale-Leaseback

    1606 Highland Ave, Vero Beach, FL 32960

    Contact for pricing
    9,616 sqft

    Nine residential buildings totaling 9,616 SF with long-term lease.

    View details
    Leased Medical Office Center
    Leased Medical Office Center

    3403 NW Federal Hwy, Jensen Beach, FL 34957

    Contact for pricing
    2.94 AC lot

    100% leased medical mix with five in-place tenants, including urgent care and physical therapy.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land at Hard Corner
    Commercial Land at Hard Corner

    6420 US Hwy 1, Vero Beach, FL 32967

    $2,849,000
    380,000 sqft 8.75 AC lot

    Commercial land with frontage on US #1 and Old Dixie Hwy, positioned near new residential development.

    View details

    Off-Market Properties in Port St Lucie, FL

    Consider similar Off-Market properties in Port St Lucie, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    544 University Blvd Ste, Unit 101
    MEDICAL BUILDING

    544 University Blvd Ste, Port St Lucie, FL 34986-2283

    Unit 101
    Estimated value:
    $215,000
    891 sqft 0.02 AC lot
    View details
    7300 Oleander Ave
    HOMES (RETIRED, NURSING)

    7300 Oleander Ave, Port St Lucie, FL 34952-8221

    Estimated value:
    $1,395,000
    64,445 sqft 27.60 AC lot
    View details
    540 University Blvd Ste, Unit 105
    MEDICAL BUILDING

    540 University Blvd Ste, Port St Lucie, FL 34986-2280

    Unit 105
    Estimated value:
    $220,000
    968 sqft 0.02 AC lot
    View details
    542 University Blvd Ste, Unit 101
    MEDICAL BUILDING

    542 University Blvd Ste, Port St Lucie, FL 34986-2282

    Unit 101
    Estimated value:
    $265,000
    2,419 sqft 0.06 AC lot
    View details
    542 University Blvd Ste, Unit 102
    MEDICAL BUILDING

    542 University Blvd Ste, Port St Lucie, FL 34986-2282

    Unit 102
    Estimated value:
    $450,000
    2,419 sqft 0.06 AC lot
    View details
    546 University Blvd Ste, Unit 204
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 204
    Estimated value:
    $215,000
    1,764 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 203
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 203
    Estimated value:
    $215,000
    1,701 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 202
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 202
    Estimated value:
    $215,000
    1,536 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 201
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 201
    Estimated value:
    $225,000
    1,782 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 104
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 104
    Estimated value:
    $225,000
    1,860 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 102
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 102
    Estimated value:
    $180,000
    1,612 sqft 0.02 AC lot
    View details

    Port St Lucie, FL Healthcare Properties Market Trends and Statistics

    Explore 22 healthcare properties for sale in Port St Lucie, FL, showcased through 11 active listings on our real estate platform. These investment opportunities span a total of 23,086 square feet of properties for sale, with an estimated market value of $6,345,000.

    Sale prices for medical real estate in Port St Lucie, FL start at $35,000, averaging $705,000, and reaching up to $3,300,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Spa & wellness properties 5
    Assisted living facilities 2
    Medical centers 2
    Medical space 2

    Demographics Overview

    Population 239K
    Population Growth (5Y) +29.5%
    Median Household Income $76,114
    College Educated 29.0%

    High-Yield Neighborhoods for Investment

    Identify Port St Lucie submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    Port Saint Lucie - 34952 $47.5K
    Port Saint Lucie - 34987 $635K
    Port Saint Lucie - 34984 $685K

    Listings Trend

    New vs delisted commercial listings in St. Lucie County

    New Delisted

    Total CRE Inventory on Market (SF)

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    Browse Healthcare properties for Sale Near Port St Lucie, FL

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    Most Searched ZIP Codes in Port St Lucie, FL

    • 34947
    • 34952
    • 34950
    • 34951
    • 34984
    • 34987

    Featured Port St Lucie Real Estate Agencies

    Realmo connects you with licensed Port St Lucie CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Atlantic Shores Realty Executives
    201 SW Port St Lucie Blvd, Suite 104 Fort Pierce, FL 34984
    Phone: 17722282111
    www.asrefl.com
    Keller Williams Realty of Port St Lucie
    9700 Reserve Boulevard Fort Pierce, FL 34986
    Phone: 17722365700
    Management Specialists
    2355 SE Seafury Lane Fort Pierce, FL 34952
    Phone: 17723809011
    www.mgtspec.com

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