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    Port St Lucie, FL Healthcare Properties for Sale

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    Free-Standing Medical Office Building
    Updated: Oct 27, 2025
    Free-Standing Medical Office Building

    1900 Nebraska Avenue, Fort Pierce, FL 34950

    $625,000
    2,100 sqft
    2,100 sq ft free‑standing medical office building
    3 exam rooms plus offices, reception office, workstations, and storage
    4 bathrooms including a full bath with shower in the doctor’s office; waiting room and employee/doctor break rooms
    9 parking spaces with a circle driveway patient drop‑off and a private carport for the doctor
    Central heating and central A/C; A/C replaced 12/28/21
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    This listing looks promising.

    Here's a quick look at some key insights for

    1900 Nebraska Avenue, Fort Pierce, FL 34950

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    • Est. Cap Rate

      4.6%
      NOI ÷ price

    • Est. NOI

      $28K
      Annual

    • Price @ 7% Cap

      $406K
      Suggested

    • Property Type

      Medical Building
      Built 1983
    View Property Analytics
    Turnkey Hair Salon Opportunity
    Updated: May 18
    Turnkey Hair Salon Opportunity

    Port St Lucie, FL

    $35,000
    1,000 sqft
    Turn‑key, fully equipped hair salon; ready for immediate operation.
    Established business with a strong client base and high income potential.
    Prime location off US1 with high visibility and traffic.
    Includes 4 hair dresser stations, manicure/pedicure stations, and ample equipment.
    Separate private room suitable for facials, massage, waxing, or make‑up.
    View details
    Free-Standing Medical Office Building
    Free-Standing Medical Office Building

    2624 S Us Highway 1, Fort Pierce, FL 34982

    $990,000
    8,000 sqft 0.50 AC lot

    Free-standing concrete block medical office with reception, waiting area, and eight exam rooms, updated and newly roofed.

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    Assisted Living Home with Pool
    Assisted Living Home with Pool

    2150 SW Imperial Street, Port St Lucie, FL 34987

    $635,000
    2,864 sqft

    Custom-built CBS pool home operating as a proven home care assisted living business with fenced yard and screened patio.

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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Assisted Living Home for Six
    Assisted Living Home for Six

    2749 SE Eagle Drive, Port St Lucie, FL 34984

    $685,000
    3,135 sqft

    Single-family home operating as an assisted living facility with capacity for six patients and three currently enrolled.

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    Turn-Key Medical Office Suite
    Turn-Key Medical Office Suite

    2506 Acorn Street Unit A-b, Fort Pierce, FL 34947

    Contact for pricing
    1,800 sqft

    Renovated medical/professional suite with five exam rooms, private offices, and two bathrooms plus a large on-site parking lot.

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    Beauty Salon with Expansion Opportunity
    Beauty Salon with Expansion Opportunity

    5022 Turnpike Feeder Road, Fort Pierce, FL 34951

    Contact for pricing
    1,536 sqft 15,000.00 AC lot

    Established beauty salon featuring 12 stations and two massage rooms in an 18-year-old CBS building.

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    Turn-Key Hair Salon Opportunity
    Turn-Key Hair Salon Opportunity

    Port St Lucie, FL 34952

    Contact for pricing
    1,000 sqft

    Well-furnished, fully equipped salon setup with multiple stations, plumbing-ready manicure and pedicure, and a private treatment room.

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    Medical Surgical Center For Sale
    Medical Surgical Center For Sale

    1811 S 25th Street, Fort Pierce, FL 34947

    Contact for pricing
    8,128 sqft 1.35 AC lot

    Licensed and operational surgical center near HCA Florida Lawnwood.

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    Restored Wellness Bungalow
    Restored Wellness Bungalow

    208 Avenue E, Fort Pierce, FL 34950

    Contact for pricing

    Restored 1920 bungalow with restored interior systems, salt cave treatment area, and multiple licensed wellness treatment rooms.

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    Spa & Wellness Business Opportunity
    Spa & Wellness Business Opportunity

    8001-7991 S Us Highway 1, Port St Lucie, FL 34952

    $60,000

    For sale spa and wellness property with an ongoing city application to add a beauty salon.

    View details
    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 11 Active listings in Port St Lucie, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 11 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Medical Office Suite with Signage
    Medical Office Suite with Signage

    3755 7th Ter 303 Suite B, Vero Beach, FL 32960

    Contact for pricing
    1,231 sqft

    Move-in-ready suite with seven flexible rooms, private restroom, and premium finishes, positioned in Vero’s medical district.

    View details
    Leased Medical Rehabilitation Center
    Leased Medical Rehabilitation Center

    3405 NW Federal Highway, Jensen Beach, FL 34957

    $3,000,000
    2.94 AC lot

    Fully leased medical and community-service center on 2.937 acres in Jensen Beach, with two tenants month-to-month.

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    Leased Medical Office Center
    Leased Medical Office Center

    3403 NW Federal Hwy, Jensen Beach, FL 34957

    Contact for pricing
    2.94 AC lot

    100% leased medical mix with five in-place tenants, including urgent care and physical therapy.

    View details
    Medical Office Building with Parking
    Medical Office Building with Parking

    3660 20th St, Vero Beach, FL 32960

    Contact for pricing

    Concrete block medical facility can be divided into two private-access spaces with 25+ parking spots along a high-traffic road.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Vero Beach Commercial Land
    Prime Vero Beach Commercial Land

    6420 US Hwy 1, Vero Beach, FL 32967

    $2,849,000
    380,000 sqft 8.75 AC lot

    8.75 acres with frontage on US #1 and Old Dixie Hwy.

    View details
    Melbourne Land Parcel For Sale
    Melbourne Land Parcel For Sale

    107 Silver Palm Avenue, Melbourne, FL 32901

    Contact for pricing
    1.25 AC lot

    1.25-acre parcel in Melbourne, Florida, near medical complexes.

    View details
    B1 Zoned Commercial Land Parcel
    B1 Zoned Commercial Land Parcel

    731 COUNTY ROAD 29, Lake Placid, FL 33852

    Contact for pricing
    0.20 AC lot

    Small commercial land parcel in B1 zoning, permitting a range of retail, personal service, medical, and certain institutional uses.

    View details
    Land Near Bethesda Hospital East
    Land Near Bethesda Hospital East

    220 SW 23rd Ave, Boynton Beach, FL 33435

    $2,500,000

    Showcase parcel near hospital, potential for various developments.

    View details

    Off-Market Properties in Port St Lucie, FL

    Consider similar Off-Market properties in Port St Lucie, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    544 University Blvd Ste, Unit 101
    MEDICAL BUILDING

    544 University Blvd Ste, Port St Lucie, FL 34986-2283

    Unit 101
    Value Estimation by Request
    891 sqft 0.02 AC lot
    View details
    7300 Oleander Ave
    HOMES (RETIRED, NURSING)

    7300 Oleander Ave, Port St Lucie, FL 34952-8221

    $1,395,000
    Estimated value
    64,445 sqft 27.60 AC lot
    View details
    540 University Blvd Ste, Unit 105
    MEDICAL BUILDING

    540 University Blvd Ste, Port St Lucie, FL 34986-2280

    Unit 105
    Value Estimation by Request
    968 sqft 0.02 AC lot
    View details
    542 University Blvd Ste, Unit 101
    MEDICAL BUILDING

    542 University Blvd Ste, Port St Lucie, FL 34986-2282

    Unit 101
    Value Estimation by Request
    2,419 sqft 0.06 AC lot
    View details
    542 University Blvd Ste, Unit 102
    MEDICAL BUILDING

    542 University Blvd Ste, Port St Lucie, FL 34986-2282

    Unit 102
    Value Estimation by Request
    2,419 sqft 0.06 AC lot
    View details
    546 University Blvd Ste, Unit 204
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 204
    Value Estimation by Request
    1,764 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 203
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 203
    Value Estimation by Request
    1,701 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 202
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 202
    Value Estimation by Request
    1,536 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 201
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 201
    Value Estimation by Request
    1,782 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 104
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 104
    Value Estimation by Request
    1,860 sqft 0.02 AC lot
    View details
    546 University Blvd Ste, Unit 102
    MEDICAL BUILDING

    546 University Blvd Ste, Port St Lucie, FL 34986-2286

    Unit 102
    Value Estimation by Request
    1,612 sqft 0.02 AC lot
    View details

    Port St Lucie, FL Healthcare Properties Market Trends and Statistics

    Explore 22 healthcare properties for sale in Port St Lucie, FL, showcased through 11 active listings on our real estate platform. These investment opportunities span a total of 29,563 square feet of properties for sale, with an estimated market value of $3,030,000.

    Sale prices for medical real estate in Port St Lucie, FL start at $35,000, averaging $505,000, and reaching up to $990,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Spa & wellness properties 6
    Assisted living facilities 2
    Medical space 2
    Medical centers 1

    Demographics Overview

    Population 239K
    Population Growth (5Y) +29.5%
    Median Household Income $76,114
    College Educated 29.0%

    High-Yield Neighborhoods for Investment

    Identify Port St Lucie submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    Port Saint Lucie - 34953 $98.3K
    Port Saint Lucie - 34952 $342.5K

    Listings Trend

    New vs delisted commercial listings in St. Lucie County

    New Delisted

    Total CRE Inventory on Market (SF)

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    Most Searched ZIP Codes in Port St Lucie, FL

    • 34947
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    • 34952
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