Medical Center

Port St Lucie, FL Medical Centers for Sale

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Eustis, FL Saint Cloud, FL Jensen Beach, FL Port Saint Lucie, FL Vero Beach, FL Cocoa, FL Stuart, FL Palm City, FL
Freestanding Medical Office Building
Updated: Aug 3
Freestanding Medical Office Building

Port St Lucie, FL

$3,300,000
11,187 sqft 1.02 AC lot
Freestanding medical office building with five medical suites
Delivered vacant with a fully built‑out professional interior
49 on‑site parking spaces
1.02‑acre property directly adjacent to HCA Florida St. Lucie Hospital
8 out of 10 AC units replaced within the last 5 years
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Freestanding Medical Office Building
Updated: Oct 27, 2025
Freestanding Medical Office Building

1900 Nebraska Avenue, Fort Pierce, FL 34950

$625,000
2,100 sqft
2,100‑square‑foot freestanding medical office building
Three exam rooms and four bathrooms, including a doctor’s bath with shower
Two offices, reception area, workstations, storage, and separate break areas
Nine parking spaces plus circular patient drop‑off driveway
Private physician carport at 1900 Nebraska Avenue
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Turn-Key Medical Office Suite
Turn-Key Medical Office Suite

2506 Acorn Street Unit A-b, Fort Pierce, FL 34947

Contact for pricing
1,800 sqft

Renovated medical/professional suite with five exam rooms, private offices, and two bathrooms plus a large on-site parking lot.

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See what stands out in St. Lucie County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

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Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 3 Active listings in Port St Lucie, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 10 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Medical Office Center with Lab
Medical Office Center with Lab

15 E E Hibiscus Boulevard, Melbourne, FL 32901

Contact for pricing
7,560 sqft

High-finish medical office center with flexible suite configurations and shared lobby access for smaller spaces.

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Medical Office Complex Near AdventHealth
Medical Office Complex Near AdventHealth

6801 US 27 Highway N, Sebring, FL 33870

$5,000,000
44,280 sqft 4.23 AC lot

Single-story healthcare property with flexible suites, assigned parking, and B2 zoning.

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Renovated Medical Office Building
Renovated Medical Office Building

1532 North Harbor City Blvd, Melbourne, FL 32935

Contact for pricing
3,200 sqft

Predominantly medical space with direct US-1 frontage, fully renovated in 2020, and delivered vacant at closing.

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Medical Office Complex Near AdventHealth
Medical Office Complex Near AdventHealth

6801 US HIGHWAY 27 N, Sebring, FL 33870

Contact for pricing

Existing suites and central air support continued medical office use in an established healthcare corridor.

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Off-Market Properties in Port St Lucie, FL

Consider similar Off-Market properties in Port St Lucie, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

544 University Blvd Ste, Unit 101
MEDICAL BUILDING

544 University Blvd Ste, Port St Lucie, FL 34986-2283

Unit 101
Estimated value:
$215,000
891 sqft 0.02 AC lot
View details
540 University Blvd Ste, Unit 105
MEDICAL BUILDING

540 University Blvd Ste, Port St Lucie, FL 34986-2280

Unit 105
Estimated value:
$220,000
968 sqft 0.02 AC lot
View details
542 University Blvd Ste, Unit 101
MEDICAL BUILDING

542 University Blvd Ste, Port St Lucie, FL 34986-2282

Unit 101
Estimated value:
$265,000
2,419 sqft 0.06 AC lot
View details
542 University Blvd Ste, Unit 102
MEDICAL BUILDING

542 University Blvd Ste, Port St Lucie, FL 34986-2282

Unit 102
Estimated value:
$450,000
2,419 sqft 0.06 AC lot
View details
546 University Blvd Ste, Unit 204
MEDICAL BUILDING

546 University Blvd Ste, Port St Lucie, FL 34986-2286

Unit 204
Estimated value:
$215,000
1,764 sqft 0.02 AC lot
View details
546 University Blvd Ste, Unit 203
MEDICAL BUILDING

546 University Blvd Ste, Port St Lucie, FL 34986-2286

Unit 203
Estimated value:
$215,000
1,701 sqft 0.02 AC lot
View details
546 University Blvd Ste, Unit 202
MEDICAL BUILDING

546 University Blvd Ste, Port St Lucie, FL 34986-2286

Unit 202
Estimated value:
$215,000
1,536 sqft 0.02 AC lot
View details
546 University Blvd Ste, Unit 201
MEDICAL BUILDING

546 University Blvd Ste, Port St Lucie, FL 34986-2286

Unit 201
Estimated value:
$225,000
1,782 sqft 0.02 AC lot
View details
546 University Blvd Ste, Unit 104
MEDICAL BUILDING

546 University Blvd Ste, Port St Lucie, FL 34986-2286

Unit 104
Estimated value:
$225,000
1,860 sqft 0.02 AC lot
View details
546 University Blvd Ste, Unit 102
MEDICAL BUILDING

546 University Blvd Ste, Port St Lucie, FL 34986-2286

Unit 102
Estimated value:
$180,000
1,612 sqft 0.02 AC lot
View details

Port St Lucie, FL Medical Centers Market Trends and Statistics

Explore 13 medical centers for sale in Port St Lucie, FL, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 15,087 square feet of properties for sale, with an estimated market value of $3,925,000.

Sale prices for medical buildings in Port St Lucie, FL start at $625,000, averaging $1,962,500, and reaching up to $3,300,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Spa & wellness properties 5
Assisted living facilities 2
Medical centers 2
Medical space 2

Demographics Overview

Population 239K
Population Growth (5Y) +29.5%
Median Household Income $76,114
College Educated 29.0%

Listings Trend

New vs delisted commercial listings in St. Lucie County

New Delisted

Total CRE Inventory on Market (SF)

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