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    South San Francisco, CA Commercial Real Estate for Lease

    82 results
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    CA, South San Francisco - Spaces Oyster Point
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    CA, South San Francisco - Spaces Oyster Point

    Discover many ways to work your way in Twin Towers

    611 Gateway Blvd, South San Francisco, CA 94080
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    Prime Retail Space in California
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    Prime Retail Space in California

    200 Airport Blvd, South San Francisco, CA 94080

    Exceptional retail leasing opportunity in a vibrant South San Francisco location.

    • Prime location in South San Francisco's bustling business district.
    • Excellent visibility and high exposure to foot traffic.
    • Ample parking available for customers.
    • Modern architecture and well‑designed, versatile spaces.
    • Proximity to major highways for convenient access.
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    South San Francisco Office/Lab Sublease
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    South San Francisco Office/Lab Sublease

    651 Gateway Blvd, South San Francisco, CA 94080

    Full floor office/lab space available for sublease through July 2029.

    • Full floor (± 22,365 RSF) divisible office/lab space available for sublease through July 2029.
    • Prominent location on Highway 101 corridor with easy access.
    • Free shuttle service to San Francisco Airport (10 minutes away).
    • Full‑building lab conversion with new laboratory infrastructure and robust MEP systems.
    • Brand new Class A exteriors, lobby, and lab warm shell core.
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    South San Francisco Flex Space
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    16,421 SF

    South San Francisco Flex Space

    Flex space with labs, vivarium, and convenient transit access.

    225 Gateway Blvd, South San Francisco, CA 94080
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    Retail Space with Ample Parking
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    1,977 SF

    Retail Space with Ample Parking

    Prime retail space with modern design and excellent visibility.

    150 Airport Blvd, South San Francisco, CA 94080
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    South San Francisco Office Space
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    South San Francisco Office Space

    13,332 SF office suite in prime location for rent.

    South San Francisco, CA 94080
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    Transit-Oriented Life Science/Tech Space
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    Transit-Oriented Life Science/Tech Space

    Class A life science and tech campus near BART and Caltrain.

    20 Phase 1, South San Francisco, CA 94080
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    South San Francisco Lab Space
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    10,709 SF

    South San Francisco Lab Space

    Lab and office flex space available for lease.

    201 Haskins Way, South San Francisco, CA 94080
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    Freestanding Industrial Building For Lease
    $15,000 / Mo

    Freestanding Industrial Building For Lease

    Freestanding building with drive-in door, easy highway access.

    320 Victory Ave, South San Francisco, CA 94080
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    South San Francisco Flex/Industrial Space
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    27,999 SF

    South San Francisco Flex/Industrial Space

    27,999 SF flex/industrial space available for lease.

    230 E Grand Ave, South San Francisco, CA 94080
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    Corner Retail and Cafe Space
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    4,893 SF

    Corner Retail and Cafe Space

    Retail and cafe spaces available in South San Francisco.

    200 Linden Ave, South San Francisco, CA 94080
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    Retail Space on Grand Avenue
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    1,166 SF

    Retail Space on Grand Avenue

    Retail space available for lease in South San Francisco.

    419 Grand Ave, South San Francisco, CA 94080
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    South San Francisco Warehouse/Office Space
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    18,772 SF

    South San Francisco Warehouse/Office Space

    Warehouse and office space available for lease in South San Francisco.

    415 E Grand Ave, South San Francisco, CA 94080
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    South San Francisco Flex Space
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    7,200 SF

    South San Francisco Flex Space

    7,200 SF flex space with office, storage, and bay views.

    390 Swift Ave, South San Francisco, CA 94080
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    South San Francisco Lab Space
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    41,077 SF

    South San Francisco Lab Space

    Equipped lab space available for lease in South San Francisco.

    951 Gateway Blvd, South San Francisco, CA 94080
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    Downtown Restaurant and Retail Space
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    3,000 SF

    Downtown Restaurant and Retail Space

    Restaurant and retail spaces available in downtown location.

    348 Grand Ave, South San Francisco, CA 94080
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    Bayfront Office Space Available
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    40,000 SF

    Bayfront Office Space Available

    Office space with bay views, restaurant, and fitness center.

    400 Oyster Point Blvd, South San Francisco, CA 94080
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    Retail Space Near CalTrain
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    3,750 SF

    Retail Space Near CalTrain

    Retail space with signage and highway access near CalTrain.

    501 S Airport Blvd, South San Francisco, CA 94080
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    Retail Space Near El Camino
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    610 SF

    Retail Space Near El Camino

    Retail space available in South San Francisco near transportation.

    988 El Camino Real, South San Francisco, CA 94080
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    South San Francisco Office Space
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    29,470 SF

    South San Francisco Office Space

    LEED Gold certified office space with excellent transportation access.

    701 Gateway Blvd, South San Francisco, CA 94080
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    Downtown Office Space Available
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    3,689 SF

    Downtown Office Space Available

    Office space in downtown core with multiple private rooms.

    301 Grand Ave, South San Francisco, CA 94080
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    Explore Similar Spaces for Sale in South San Francisco, CA

    Consider Similar Space for Sale. We found 17 Spaces in Nearby Locations matching your search parameters.

    Established Property Inspection Business For Sale
    $200,000
    1,840 SF

    Established Property Inspection Business For Sale

    Property inspection business serving South San Francisco and the Bay Area.

    461 Alta Vista Dr, South San Francisco, CA 94080
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    Downtown South San Francisco Investment
    $1,799,000

    Downtown South San Francisco Investment

    2,760 SF customizable space in thriving downtown South SF.

    20-24 Linden Ave, South San Francisco, CA 94080
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    South San Francisco Warehouse Opportunity
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    33,000 SF

    South San Francisco Warehouse Opportunity

    Value-add warehouse facility with upside potential in South San Francisco.

    1373 Lowrie Ave, South San Francisco, CA 94080
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    South San Francisco, CA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in South San Francisco, CA with 97 listings featured on our commercial real estate exchange. The current inventory includes 31,573,377,000 square feet of properties with an estimated lease value of $105 SF/Yr.

    Estimated lease rates for Commercial real estate in South San Francisco, CA begin at $2 SF/Yr, with an average of $15 SF/Yr and extend to $26 SF/Yr.
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    Browse Commercial real estate for Lease Near South San Francisco, CA

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